Changes in the Metabolic Footprint of Placental Explant-Conditioned Culture Medium Identifies Metabolic Disturbances Related to Hypoxia and Pre-Eclampsia

Placenta

Volumn 30, Issue 11, 2009, Pages 974-980

  Dunn, W B ^a   Brown, M ^a   Worton, S A ^a   Crocker, I P ^a   Broadhurst, D ^b   Horgan, R ^a,b   Kenny, L C ^b   Baker, P N ^a   Kell, D B ^a   Heazell, A E P ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Hypoxia; Metabolic footprint; Metabolomics; Oxygen tension; Placental villous explants; Pre eclampsia

Indexed keywords

CYSTAMINE; DIACYLGLYCEROL; GLUTAMIC ACID; GLUTAMINE; GLYCEROL; KYNURENINE; LEUKOTRIENE; TRYPTOPHAN;

ARTICLE; CULTURE MEDIUM; EXPLANT; FEMALE; HUMAN; HUMAN TISSUE; HYPOXIA; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETER; METABOLIC DISORDER; METABOLISM; METABOLITE; PATHOGENESIS; PLACENTA; PREECLAMPSIA; PREGNANCY; PRIORITY JOURNAL; PROSTAGLANDIN METABOLISM; SERUM; SYSTEMS BIOLOGY; TISSUE CULTURE;

ANIMALS; ANOXIA; CHROMATOGRAPHY, LIQUID; CULTURE MEDIA, CONDITIONED; FEMALE; MASS SPECTROMETRY; METABOLOMICS; PLACENTA; PRE-ECLAMPSIA; PREGNANCY;

EID: 70449099323     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.placenta.2009.08.008     Document Type: Article

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