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Volumn 113, Issue SUPPL. 3, 2006, Pages 118-135

The use of high-dimensional biology (genomics, transcriptomics, proteomics, and metabolomics) to understand the preterm parturition syndrome

Author keywords

Analytical tools; Genetics; High throughput; Omics; Predisposing factors; Preterm birth; Preterm labour; Systems biology

Indexed keywords

ANTIBIOTIC AGENT; ANTIOXIDANT; ARYLDIALKYLPHOSPHATASE 1; BETAINE; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CD14 ANTIGEN; CHOLINE; CYANOCOBALAMIN; FAS ANTIGEN; FOLIC ACID; GELATINASE B; HEAT SHOCK PROTEIN 47; HEAT SHOCK PROTEIN 70; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; MESSENGER RNA; NEUTROPHIL COLLAGENASE; STEROID; TRANSFORMING GROWTH FACTOR BETA1; TRICHOSTATIN A; TUMOR NECROSIS FACTOR ALPHA;

EID: 33845567710     PISSN: 14700328     EISSN: 14710528     Source Type: Journal    
DOI: 10.1111/j.1471-0528.2006.01150.x     Document Type: Review
Times cited : (174)

References (204)
  • 1
    • 33745588546 scopus 로고    scopus 로고
    • The limits of reductionism in medicine: Could systems biology offer an alternative?
    • Ahn AC, Tewari M, Poon CS, Phillips RS. The limits of reductionism in medicine: could systems biology offer an alternative? PLoS Med 2006;3:e208.
    • (2006) PLoS Med , vol.3
    • Ahn, A.C.1    Tewari, M.2    Poon, C.S.3    Phillips, R.S.4
  • 2
    • 17644365470 scopus 로고    scopus 로고
    • The end of "naive reductionism": Rise of systems biology or renaissance of physiology?
    • Strange K. The end of "naive reductionism": rise of systems biology or renaissance of physiology? Am J Physiol Cell Physiol 2005;288:C968-74.
    • (2005) Am J Physiol Cell Physiol , vol.288
    • Strange, K.1
  • 3
    • 0033951108 scopus 로고    scopus 로고
    • Designer science and the "omic" revolution
    • Evans GA. Designer science and the "omic" revolution. Nat Biotechnol 2000;18:127.
    • (2000) Nat Biotechnol , vol.18 , pp. 127
    • Evans, G.A.1
  • 4
    • 0037974525 scopus 로고    scopus 로고
    • Application of microarray technology in environmental and comparative physiology
    • Gracey AY, Cossins AR. Application of microarray technology in environmental and comparative physiology. Annu Rev Physiol 2003;65:231-59.
    • (2003) Annu Rev Physiol , vol.65 , pp. 231-259
    • Gracey, A.Y.1    Cossins, A.R.2
  • 5
    • 4444371602 scopus 로고    scopus 로고
    • Towards sound epistemological foundations of statistical methods for HDB
    • Mehta T, Tanik M, Allison DB. Towards sound epistemological foundations of statistical methods for HDB. Nat Genet 2004;36:943-7.
    • (2004) Nat Genet , vol.36 , pp. 943-947
    • Mehta, T.1    Tanik, M.2    Allison, D.B.3
  • 7
    • 0032561082 scopus 로고    scopus 로고
    • Fishing expeditions
    • Weinstein JN. Fishing expeditions. Science 1998;282:628-9.
    • (1998) Science , vol.282 , pp. 628-629
    • Weinstein, J.N.1
  • 8
    • 0036667384 scopus 로고    scopus 로고
    • 'Omic' and hypothesis-driven research in the molecular pharmacology of cancer
    • Weinstein JN. 'Omic' and hypothesis-driven research in the molecular pharmacology of cancer. Curr Opin Pharmacol 2002;2:361-5.
    • (2002) Curr Opin Pharmacol , vol.2 , pp. 361-365
    • Weinstein, J.N.1
  • 9
    • 16644403439 scopus 로고    scopus 로고
    • Are histochemistry and cytochemistry 'Omics'?
    • Coulton G. Are histochemistry and cytochemistry 'Omics'? J Mol Histol 2004;35:603-13.
    • (2004) J Mol Histol , vol.35 , pp. 603-613
    • Coulton, G.1
  • 10
    • 0036941857 scopus 로고    scopus 로고
    • Looking beyond the details: A rise in system-oriented approaches in genetics andmolecular biology
    • Kitano H. Looking beyond the details: a rise in system-oriented approaches in genetics andmolecular biology. Curr Genet 2002;41:1-10.
    • (2002) Curr Genet , vol.41 , pp. 1-10
    • Kitano, H.1
  • 11
    • 0036500993 scopus 로고    scopus 로고
    • Systems biology: A brief overview
    • Kitano H. Systems biology: a brief overview. Science 2002;295:1662-4.
    • (2002) Science , vol.295 , pp. 1662-1664
    • Kitano, H.1
  • 12
    • 0037866424 scopus 로고    scopus 로고
    • Leroy Hood expounds the principles, practice and future of systems biology
    • Hood L. Leroy Hood expounds the principles, practice and future of systems biology. Drug Discov Today 2003;8:436-8.
    • (2003) Drug Discov Today , vol.8 , pp. 436-438
    • Hood, L.1
  • 13
    • 0037288767 scopus 로고    scopus 로고
    • Systems biology: Integrating technology, biology, and computation
    • Hood L. Systems biology: integrating technology, biology, and computation. Mech Ageing Dev 2003;124:9-16.
    • (2003) Mech Ageing Dev , vol.124 , pp. 9-16
    • Hood, L.1
  • 14
    • 7444253428 scopus 로고    scopus 로고
    • Systems biology and new technologies enable predictive and preventative medicine
    • Hood L, Heath JR, Phelps ME, Lin B. Systems biology and new technologies enable predictive and preventative medicine. Science 2004;306:640-3.
    • (2004) Science , vol.306 , pp. 640-643
    • Hood, L.1    Heath, J.R.2    Phelps, M.E.3    Lin, B.4
  • 16
    • 0035860972 scopus 로고    scopus 로고
    • Genetics moves into the medical mainstream
    • Collins FS, Guttmacher AE. Genetics moves into the medical mainstream. JAMA 2001;286:2322-4.
    • (2001) JAMA , vol.286 , pp. 2322-2324
    • Collins, F.S.1    Guttmacher, A.E.2
  • 17
    • 0035169803 scopus 로고    scopus 로고
    • Revealing the shared inheritance of all humankind
    • The Human Genome Project
    • Collins FS, Mansoura MK. The Human Genome Project. Revealing the shared inheritance of all humankind. Cancer 2001;91:221-5.
    • (2001) Cancer , vol.91 , pp. 221-225
    • Collins, F.S.1    Mansoura, M.K.2
  • 18
    • 0035575568 scopus 로고    scopus 로고
    • Personalized medicine: Revolutionizing drug discovery and patient care
    • Ginsburg GS, McCarthy JJ. Personalized medicine: revolutionizing drug discovery and patient care. Trends Biotechnol 2001;19:491-6.
    • (2001) Trends Biotechnol , vol.19 , pp. 491-496
    • Ginsburg, G.S.1    McCarthy, J.J.2
  • 19
    • 0035861038 scopus 로고    scopus 로고
    • The anatomy of the human genome: A neo-Vesalian basis for medicine in the 21st century
    • McKusick VA. The anatomy of the human genome: a neo-Vesalian basis for medicine in the 21st century. JAMA 2001;286:2289-95.
    • (2001) JAMA , vol.286 , pp. 2289-2295
    • McKusick, V.A.1
  • 20
    • 0035861004 scopus 로고    scopus 로고
    • Implications of the human genome for understanding human biology and medicine
    • Subramanian G, Adams MD, Venter JC, Broder S. Implications of the human genome for understanding human biology and medicine. JAMA 2001;286:2296-307.
    • (2001) JAMA , vol.286 , pp. 2296-2307
    • Subramanian, G.1    Adams, M.D.2    Venter, J.C.3    Broder, S.4
  • 21
    • 0028834721 scopus 로고
    • Maternal ingestion of ortho-aminoacetophenone during gestation affects intake by offspring
    • Nolte DL, Mason JR. Maternal ingestion of ortho-aminoacetophenone during gestation affects intake by offspring. Physiol Behav 1995;58:925-8.
    • (1995) Physiol Behav , vol.58 , pp. 925-928
    • Nolte, D.L.1    Mason, J.R.2
  • 23
    • 0032104760 scopus 로고    scopus 로고
    • Comparative studies on the initiation of labor
    • Nathanielsz PW. Comparative studies on the initiation of labor. Eur J Obstet Gynecol Reprod Biol 1998;78:127-32.
    • (1998) Eur J Obstet Gynecol Reprod Biol , vol.78 , pp. 127-132
    • Nathanielsz, P.W.1
  • 24
    • 0024193393 scopus 로고
    • Urinary concentrations of ovarian steroid hormone metabolites and bioactive follicle-stimulating hormone in killer whales (Orcinus orchus) during ovarian cycles and pregnancy
    • Walker LA, Cornell L, Dahl KD, Czekala NM, Dargen CM, Joseph B, et al. Urinary concentrations of ovarian steroid hormone metabolites and bioactive follicle-stimulating hormone in killer whales (Orcinus orchus) during ovarian cycles and pregnancy. Biol Reprod 1988;39:1013-20.
    • (1988) Biol Reprod , vol.39 , pp. 1013-1020
    • Walker, L.A.1    Cornell, L.2    Dahl, K.D.3    Czekala, N.M.4    Dargen, C.M.5    Joseph, B.6
  • 25
    • 27844600660 scopus 로고    scopus 로고
    • Placentation in the African elephant, Loxodonta africana. IV. Growth and function of the fetal gonads
    • Allen WR, Mathias S, Ford M. Placentation in the African elephant, Loxodonta africana. IV. Growth and function of the fetal gonads. Reproduction 2005;130:713-20.
    • (2005) Reproduction , vol.130 , pp. 713-720
    • Allen, W.R.1    Mathias, S.2    Ford, M.3
  • 26
    • 0036119436 scopus 로고    scopus 로고
    • Influence of maternal size on placental, fetal and postnatal growth in the horse. I. Development in utero
    • Allen WR, Wilsher S, Turnbull C, Stewart F, Ousey J, Rossdale PD, et al. Influence of maternal size on placental, fetal and postnatal growth in the horse. I. Development in utero. Reproduction 2002;123:445-53.
    • (2002) Reproduction , vol.123 , pp. 445-453
    • Allen, W.R.1    Wilsher, S.2    Turnbull, C.3    Stewart, F.4    Ousey, J.5    Rossdale, P.D.6
  • 28
    • 0036238274 scopus 로고    scopus 로고
    • Pregnancy and the Ehlers-Danlos syndrome: A retrospective study in a Dutch population
    • Lind J, Wallenburg HC. Pregnancy and the Ehlers-Danlos syndrome: a retrospective study in a Dutch population. Acta Obstet Gynecol Scand 2002;81:293-300.
    • (2002) Acta Obstet Gynecol Scand , vol.81 , pp. 293-300
    • Lind, J.1    Wallenburg, H.C.2
  • 30
    • 20344369286 scopus 로고    scopus 로고
    • The genetic contribution towards preterm delivery
    • Adams KM, Eschenbach DA. The genetic contribution towards preterm delivery. Semin Fetal Neonatal Med 2004;9:445-52.
    • (2004) Semin Fetal Neonatal Med , vol.9 , pp. 445-452
    • Adams, K.M.1    Eschenbach, D.A.2
  • 31
    • 14644394892 scopus 로고    scopus 로고
    • Current understanding of genetic factors in preterm birth
    • Varner MW, Esplin MS. Current understanding of genetic factors in preterm birth. BJOG 2005;112(Suppl 1):28-31.
    • (2005) BJOG , vol.112 , Issue.SUPPL. 1 , pp. 28-31
    • Varner, M.W.1    Esplin, M.S.2
  • 32
    • 0029810052 scopus 로고    scopus 로고
    • Preterm delivery and perinatal death among black and white infants in a Chicago-area perinatal registry
    • Schieve LA, Handler A. Preterm delivery and perinatal death among black and white infants in a Chicago-area perinatal registry. Obstet Gynecol 1996;88:356-63.
    • (1996) Obstet Gynecol , vol.88 , pp. 356-363
    • Schieve, L.A.1    Handler, A.2
  • 33
    • 0036380973 scopus 로고    scopus 로고
    • Prediction of preterm premature rupture of membranes by transvaginal ultrasound features and risk factors in a high-risk population
    • Odibo AO, Talucci M, Berghella V. Prediction of preterm premature rupture of membranes by transvaginal ultrasound features and risk factors in a high-risk population. Ultrasound Obstet Gynecol 2002;20:245-51.
    • (2002) Ultrasound Obstet Gynecol , vol.20 , pp. 245-251
    • Odibo, A.O.1    Talucci, M.2    Berghella, V.3
  • 34
    • 0036854210 scopus 로고    scopus 로고
    • The design, execution, and interpretation of genetic association studies to decipher complex diseases
    • Romero R, Kuivaniemi H, Tromp G, Olson J. The design, execution, and interpretation of genetic association studies to decipher complex diseases. Am J Obstet Gynecol 2002;187:1299-312.
    • (2002) Am J Obstet Gynecol , vol.187 , pp. 1299-1312
    • Romero, R.1    Kuivaniemi, H.2    Tromp, G.3    Olson, J.4
  • 36
    • 0031921309 scopus 로고    scopus 로고
    • Familial patterns in birth characteristics: Impact on individual and population risks
    • Winkvist A, Mogren I, Hogberg U. Familial patterns in birth characteristics: impact on individual and population risks. Int J Epidemiol 1998;27:248-54.
    • (1998) Int J Epidemiol , vol.27 , pp. 248-254
    • Winkvist, A.1    Mogren, I.2    Hogberg, U.3
  • 37
    • 0034018471 scopus 로고    scopus 로고
    • Genetic influence on birthweight and gestational length determined by studies in offspring of twins
    • Clausson B, Lichtenstein P, Cnattingius S. Genetic influence on birthweight and gestational length determined by studies in offspring of twins. BJOG 2000;107:375-81.
    • (2000) BJOG , vol.107 , pp. 375-381
    • Clausson, B.1    Lichtenstein, P.2    Cnattingius, S.3
  • 38
    • 0033916562 scopus 로고    scopus 로고
    • Genetic influences on premature parturition in an Australian twin sample
    • Treloar SA, Macones GA, Mitchell LE, Martin NG. Genetic influences on premature parturition in an Australian twin sample. Twin Res 2000;3:80-2.
    • (2000) Twin Res , vol.3 , pp. 80-82
    • Treloar, S.A.1    Macones, G.A.2    Mitchell, L.E.3    Martin, N.G.4
  • 42
    • 0034763963 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha promoter variant 2 (TNF2) is associated with pre-term delivery, infant mortality, and malaria morbidity in western Kenya: Asembo Bay Cohort Project IX
    • Aidoo M, McElroy PD, Kolczak MS, Terlouw DJ, ter Kuile FO, Nahlen B, et al. Tumor necrosis factor-alpha promoter variant 2 (TNF2) is associated with pre-term delivery, infant mortality, and malaria morbidity in western Kenya: Asembo Bay Cohort Project IX. Genet Epidemiol 2001;21:201-11.
    • (2001) Genet Epidemiol , vol.21 , pp. 201-211
    • Aidoo, M.1    McElroy, P.D.2    Kolczak, M.S.3    Terlouw, D.J.4    Ter Kuile, F.O.5    Nahlen, B.6
  • 43
    • 20544441986 scopus 로고    scopus 로고
    • Risk of spontaneous pretermbirth is associated with common proinflammatory cytokine polymorphisms
    • Engel SA, Erichsen HC, Savitz DA, Thorp J, Chanock SJ, Olshan AF. Risk of spontaneous pretermbirth is associated with common proinflammatory cytokine polymorphisms. Epidemiology 2005;16:469-77.
    • (2005) Epidemiology , vol.16 , pp. 469-477
    • Engel, S.A.1    Erichsen, H.C.2    Savitz, D.A.3    Thorp, J.4    Chanock, S.J.5    Olshan, A.F.6
  • 44
    • 4344635779 scopus 로고    scopus 로고
    • Polymorphisms of the paraoxonase gene and risk of preterm delivery
    • Chen D, Hu Y, Chen C, Yang F, Fang Z, Wang L, et al. Polymorphisms of the paraoxonase gene and risk of preterm delivery. Epidemiology 2004;15:466-70.
    • (2004) Epidemiology , vol.15 , pp. 466-470
    • Chen, D.1    Hu, Y.2    Chen, C.3    Yang, F.4    Fang, Z.5    Wang, L.6
  • 45
    • 33745258365 scopus 로고    scopus 로고
    • Multilocus interactions at maternal tumor necrosis factor-alpha, tumor necrosis factor receptors, interleukin-6 and interleukin-6 receptor genes predict spontaneous preterm labor in European-American women
    • Menon R, Velez DR, Simhan H, Ryckman K, Jiang L, Thorsen P, et al. Multilocus interactions at maternal tumor necrosis factor-alpha, tumor necrosis factor receptors, interleukin-6 and interleukin-6 receptor genes predict spontaneous preterm labor in European-American women. Am J Obstet Gynecol 2006;194:1616-24.
    • (2006) Am J Obstet Gynecol , vol.194 , pp. 1616-1624
    • Menon, R.1    Velez, D.R.2    Simhan, H.3    Ryckman, K.4    Jiang, L.5    Thorsen, P.6
  • 46
    • 10044292767 scopus 로고    scopus 로고
    • Interleukins-1, -4, -6, -10, tumor necrosis factor, transforming growth factor-beta, FAS, and mannose-binding protein C gene polymorphisms in Australian women: Risk of preterm birth
    • Annells MF, Hart PH, Mullighan CG, Heatley SL, Robinson JS, Bardy P, et al. Interleukins-1, -4, -6, -10, tumor necrosis factor, transforming growth factor-beta, FAS, and mannose-binding protein C gene polymorphisms in Australian women: risk of preterm birth. Am J Obstet Gynecol 2004;191:2056-67.
    • (2004) Am J Obstet Gynecol , vol.191 , pp. 2056-2067
    • Annells, M.F.1    Hart, P.H.2    Mullighan, C.G.3    Heatley, S.L.4    Robinson, J.S.5    Bardy, P.6
  • 47
    • 33845592436 scopus 로고    scopus 로고
    • Carriage of a low-secretory phenotype C allele of the interleukin (IL)-6-174 (G/C) polymorphism is associated with preterm delivery and idiopathic preterm labour (<32 weeks)
    • (abstract)
    • Orsi NM, Logghe HL, Gopichandran N, Bottomley L, Lynch K, Levene MI, et al. Carriage of a low-secretory phenotype C allele of the interleukin (IL)-6-174 (G/C) polymorphism is associated with preterm delivery and idiopathic preterm labour (<32 weeks). J Soc Gynecol Investig 2003;2:320A (abstract).
    • (2003) J Soc Gynecol Investig , vol.2
    • Orsi, N.M.1    Logghe, H.L.2    Gopichandran, N.3    Bottomley, L.4    Lynch, K.5    Levene, M.I.6
  • 48
    • 33845564406 scopus 로고    scopus 로고
    • Carriage of the mutant high-secretory phenotype G allele of the interleukin (IL)-10-1082 (A/G) is associated with preterm delivery and premature rupture of membranes (<32 weeks)
    • (abstract)
    • Orsi NM, Logghe HL, Gopichandran N, Bottomley L, Lynch K, Levene MI, et al. Carriage of the mutant high-secretory phenotype G allele of the interleukin (IL)-10-1082 (A/G) is associated with preterm delivery and premature rupture of membranes (<32 weeks). J Soc Gynecol Investig 2003;2:318A (abstract).
    • (2003) J Soc Gynecol Investig , vol.2
    • Orsi, N.M.1    Logghe, H.L.2    Gopichandran, N.3    Bottomley, L.4    Lynch, K.5    Levene, M.I.6
  • 49
    • 33845579186 scopus 로고    scopus 로고
    • Variation in the interlukin-1beta-511 polymorphism genotype is associated with gestational length in women from the Indian sub-continent who delivered preterm
    • (abstract)
    • Greenfield PJ, Kessling AM, Lamont RF. Variation in the interlukin-1beta-511 polymorphism genotype is associated with gestational length in women from the Indian sub-continent who delivered preterm. J Soc Gynecol Investig 2003;2:320A (abstract).
    • (2003) J Soc Gynecol Investig , vol.2
    • Greenfield, P.J.1    Kessling, A.M.2    Lamont, R.F.3
  • 50
    • 33747322736 scopus 로고    scopus 로고
    • Evidence for an association between mannose-binding lectin 2 (MBL2) gene polymorphisms and pre-term birth
    • Bodamer OA, Mitterer G, Maurer W, Pollak A, Mueller MW, Schmidt WM. Evidence for an association between mannose-binding lectin 2 (MBL2) gene polymorphisms and pre-term birth. Genet Med 2006;8:518-24.
    • (2006) Genet Med , vol.8 , pp. 518-524
    • Bodamer, O.A.1    Mitterer, G.2    Maurer, W.3    Pollak, A.4    Mueller, M.W.5    Schmidt, W.M.6
  • 52
    • 0037155249 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the matrix metalloproteinase-1 (MMP-1) promoter influences amnion cell MMP-1 expression and risk for preterm premature rupture of the fetal membranes
    • Fujimoto T, Parry S, Urbanek M, Sammel M, Macones G, Kuivaniemi H, et al. A single nucleotide polymorphism in the matrix metalloproteinase-1 (MMP-1) promoter influences amnion cell MMP-1 expression and risk for preterm premature rupture of the fetal membranes. J Biol Chem 2002;277:6296-302.
    • (2002) J Biol Chem , vol.277 , pp. 6296-6302
    • Fujimoto, T.1    Parry, S.2    Urbanek, M.3    Sammel, M.4    Macones, G.5    Kuivaniemi, H.6
  • 53
    • 8444220043 scopus 로고    scopus 로고
    • Functionally significant SNP MMP8 promoter haplotypes and preterm premature rupture of membranes (PPROM)
    • Wang H, Parry S, Macones G, Sammel MD, Ferrand PE, Kuivaniemi H, et al. Functionally significant SNP MMP8 promoter haplotypes and preterm premature rupture of membranes (PPROM). Hum Mol Genet 2004;13:2659-69.
    • (2004) Hum Mol Genet , vol.13 , pp. 2659-2669
    • Wang, H.1    Parry, S.2    Macones, G.3    Sammel, M.D.4    Ferrand, P.E.5    Kuivaniemi, H.6
  • 54
    • 0036262963 scopus 로고    scopus 로고
    • A polymorphism in the matrix metalloproteinase-9 promoter is associated with increased risk of preterm premature rupture of membranes in African Americans
    • Ferrand PE, Parry S, Sammel M, Macones GA, Kuivaniemi H, Romero R, et al. A polymorphism in the matrix metalloproteinase-9 promoter is associated with increased risk of preterm premature rupture of membranes in African Americans. Mol Hum Reprod 2002;8:494-501.
    • (2002) Mol Hum Reprod , vol.8 , pp. 494-501
    • Ferrand, P.E.1    Parry, S.2    Sammel, M.3    Macones, G.A.4    Kuivaniemi, H.5    Romero, R.6
  • 55
    • 0036848445 scopus 로고    scopus 로고
    • The CARD15 2936insC mutation and TLR4 896 A>G polymorphismin African Americans and risk of pretermpremature rupture of membranes (PPROM)
    • Ferrand PE, Fujimoto T, Chennathukuzhi V, Parry S, Macones GA, Sammel M, et al. The CARD15 2936insC mutation and TLR4 896 A>G polymorphismin African Americans and risk of pretermpremature rupture of membranes (PPROM). Mol Hum Reprod 2002;8:1031-4.
    • (2002) Mol Hum Reprod , vol.8 , pp. 1031-1034
    • Ferrand, P.E.1    Fujimoto, T.2    Chennathukuzhi, V.3    Parry, S.4    Macones, G.A.5    Sammel, M.6
  • 56
    • 0010243393 scopus 로고    scopus 로고
    • Association of polymorphism within the promoter of the tumor necrosis factor alpha gene with increased risk of preterm premature rupture of the fetal membranes
    • Roberts AK, Monzon-Bordonaba F, Van Deerlin PG, Holder J, Macones GA, Morgan MA, et al. Association of polymorphism within the promoter of the tumor necrosis factor alpha gene with increased risk of preterm premature rupture of the fetal membranes. Am J Obstet Gynecol 1999;180:1297-302.
    • (1999) Am J Obstet Gynecol , vol.180 , pp. 1297-1302
    • Roberts, A.K.1    Monzon-Bordonaba, F.2    Van Deerlin, P.G.3    Holder, J.4    Macones, G.A.5    Morgan, M.A.6
  • 57
    • 7044224933 scopus 로고    scopus 로고
    • Polymorphisms in the tumor necrosis factor-alpha gene at position -308 and the inducible 70 kd heat shock protein gene at position +1267 in multifetal pregnancies and preterm premature rupture of fetal membranes
    • Kalish RB, Vardhana S, Gupta M, Perni SC, Chasen ST, Witkin SS. Polymorphisms in the tumor necrosis factor-alpha gene at position -308 and the inducible 70 kd heat shock protein gene at position +1267 in multifetal pregnancies and preterm premature rupture of fetal membranes. Am J Obstet Gynecol 2004;191:1368-74.
    • (2004) Am J Obstet Gynecol , vol.191 , pp. 1368-1374
    • Kalish, R.B.1    Vardhana, S.2    Gupta, M.3    Perni, S.C.4    Chasen, S.T.5    Witkin, S.S.6
  • 59
    • 0036077629 scopus 로고    scopus 로고
    • Polymorphism in the interleukin-1 gene complex and spontaneous preterm delivery
    • Genc MR, Gerber S, Nesin M, Witkin SS. Polymorphism in the interleukin-1 gene complex and spontaneous preterm delivery. Am J Obstet Gynecol 2002;187:157-63.
    • (2002) Am J Obstet Gynecol , vol.187 , pp. 157-163
    • Genc, M.R.1    Gerber, S.2    Nesin, M.3    Witkin, S.S.4
  • 60
    • 33646342782 scopus 로고    scopus 로고
    • Association of a maternal CD14 -159 gene polymorphism with preterm premature rupture of membranes and spontaneous preterm birth in multi-fetal pregnancies
    • Kalish RB, Vardhana S, Normand NJ, Gupta M, Witkin SS. Association of a maternal CD14 -159 gene polymorphism with preterm premature rupture of membranes and spontaneous preterm birth in multi-fetal pregnancies. J Reprod Immunol 2006;70:109-17.
    • (2006) J Reprod Immunol , vol.70 , pp. 109-117
    • Kalish, R.B.1    Vardhana, S.2    Normand, N.J.3    Gupta, M.4    Witkin, S.S.5
  • 61
    • 12844260927 scopus 로고    scopus 로고
    • A single nucleotide A>G polymorphism at position -670 in the Fas gene promoter: Relationship to preterm premature rupture of fetal membranes in multifetal pregnancies
    • Kalish RB, Nguyen DP, Vardhana S, Gupta M, Perni SC, Witkin SS. A single nucleotide A>G polymorphism at position -670 in the Fas gene promoter: relationship to preterm premature rupture of fetal membranes in multifetal pregnancies. Am J Obstet Gynecol 2005;192:208-12.
    • (2005) Am J Obstet Gynecol , vol.192 , pp. 208-212
    • Kalish, R.B.1    Nguyen, D.P.2    Vardhana, S.3    Gupta, M.4    Perni, S.C.5    Witkin, S.S.6
  • 62
    • 24644519410 scopus 로고    scopus 로고
    • Polymorphism of Fas and Fas ligand in preterm premature rupture of membranes in singleton pregnancies
    • Fuks A, Parton LA, Polavarapu S, Netta D, Strassberg S, Godi I, et al. Polymorphism of Fas and Fas ligand in preterm premature rupture of membranes in singleton pregnancies. Am J Obstet Gynecol 2005;193:1132-6.
    • (2005) Am J Obstet Gynecol , vol.193 , pp. 1132-1136
    • Fuks, A.1    Parton, L.A.2    Polavarapu, S.3    Netta, D.4    Strassberg, S.5    Godi, I.6
  • 63
    • 33748631588 scopus 로고    scopus 로고
    • A functional SNP in the promoter of the SERPINH1 gene increases risk of preterm premature rupture of membranes in African Americans
    • Wang H, Parry S, Macones G, Sammel MD, Kuivaniemi H, Tromp G, et al. A functional SNP in the promoter of the SERPINH1 gene increases risk of preterm premature rupture of membranes in African Americans. Proc Natl Acad Sci U S A 2006;103:13463-7.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 13463-13467
    • Wang, H.1    Parry, S.2    Macones, G.3    Sammel, M.D.4    Kuivaniemi, H.5    Tromp, G.6
  • 64
    • 28644438349 scopus 로고    scopus 로고
    • Genetic variation associated with preterm birth: A HuGE review
    • Crider KS, Whitehead N, Buus RM. Genetic variation associated with preterm birth: a HuGE review. Genet Med 2005;7:593-604.
    • (2005) Genet Med , vol.7 , pp. 593-604
    • Crider, K.S.1    Whitehead, N.2    Buus, R.M.3
  • 65
    • 33845598120 scopus 로고
    • Expression of matrix degrading enzymes and tissue inhibitors of metalloproteinases (TIMP) in human fetal membranes
    • Presented at. Georgia, January 23-28, Atlanta, (abstract)
    • Fortunato SJ, Menon R, Swan K, Baricos W. Expression of matrix degrading enzymes and tissue inhibitors of metalloproteinases (TIMP) in human fetal membranes. Presented at 15th annual meeting of the Society of Perinatal Obstetricians. Georgia, January 23-28, Atlanta, 1995 (abstract).
    • (1995) 15th Annual Meeting of the Society of Perinatal Obstetricians
    • Fortunato, S.J.1    Menon, R.2    Swan, K.3    Baricos, W.4
  • 66
    • 84890969929 scopus 로고    scopus 로고
    • Induction of MMP-9 and normal presence of MMP-2, TIMP-1and 2 in human fetal membranes
    • 17th annual meeting of the Society of Perinatal Obstetricians Anaheim
    • Fortunato SJ, Menon R, Lombardi S. Induction of MMP-9 and normal presence of MMP-2, TIMP-1and 2 in human fetal membranes. 17th annual meeting of the Society of Perinatal Obstetricians Anaheim. Am J Obstet Gynecol 1997;176:1.
    • (1997) Am J Obstet Gynecol , vol.176 , pp. 1
    • Fortunato, S.J.1    Menon, R.2    Lombardi, S.3
  • 67
    • 0037507321 scopus 로고    scopus 로고
    • Collagenase-3 (MMP-13) in fetal membranes and amniotic fluid during pregnancy
    • Fortunato SJ, LaFleur B, Menon R. Collagenase-3 (MMP-13) in fetal membranes and amniotic fluid during pregnancy. Am J Reprod Immunol 2003;49:120-5.
    • (2003) Am J Reprod Immunol , vol.49 , pp. 120-125
    • Fortunato, S.J.1    LaFleur, B.2    Menon, R.3
  • 68
    • 0029876294 scopus 로고    scopus 로고
    • Increased matrix metalloproteinase activity and reduced tissue inhibitor of metalloproteinases-1 levels in amniotic fluids from pregnancies complicated by premature rupture of membranes
    • Vadillo-Ortega F, Hernandez A, Gonzalez-Avila G, Bermejo L, Iwata K, Strauss JF III. Increased matrix metalloproteinase activity and reduced tissue inhibitor of metalloproteinases-1 levels in amniotic fluids from pregnancies complicated by premature rupture of membranes. Am J Obstet Gynecol 1996;174:1371-6.
    • (1996) Am J Obstet Gynecol , vol.174 , pp. 1371-1376
    • Vadillo-Ortega, F.1    Hernandez, A.2    Gonzalez-Avila, G.3    Bermejo, L.4    Iwata, K.5    Strauss III, J.F.6
  • 70
    • 0033883875 scopus 로고    scopus 로고
    • Human neutrophil collagenase (matrix metalloproteinase 8) in parturition, premature rupture of the membranes, and intrauterine infection
    • Maymon E, Romero R, Pacora P, Gomez R, Athayde N, Edwin S, et al. Human neutrophil collagenase (matrix metalloproteinase 8) in parturition, premature rupture of the membranes, and intrauterine infection. Am J Obstet Gynecol 2000;183:94-9.
    • (2000) Am J Obstet Gynecol , vol.183 , pp. 94-99
    • Maymon, E.1    Romero, R.2    Pacora, P.3    Gomez, R.4    Athayde, N.5    Edwin, S.6
  • 72
    • 7244234068 scopus 로고    scopus 로고
    • Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success
    • Hiby SE, Walker JJ, O'shaughnessy KM, Redman CW, Carrington M, Trowsdale J, et al. Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success. J Exp Med 2004;200:957-65.
    • (2004) J Exp Med , vol.200 , pp. 957-965
    • Hiby, S.E.1    Walker, J.J.2    O'Shaughnessy, K.M.3    Redman, C.W.4    Carrington, M.5    Trowsdale, J.6
  • 73
    • 26944457027 scopus 로고    scopus 로고
    • Recurrence of pre-eclampsia across generations: Exploring fetal and maternal genetic components in a population based cohort
    • Skjaerven R, Vatten LJ, Wilcox AJ, Ronning T, Irgens LM, Lie RT. Recurrence of pre-eclampsia across generations: exploring fetal and maternal genetic components in a population based cohort. BMJ 2005;331:877.
    • (2005) BMJ , vol.331 , pp. 877
    • Skjaerven, R.1    Vatten, L.J.2    Wilcox, A.J.3    Ronning, T.4    Irgens, L.M.5    Lie, R.T.6
  • 74
    • 84942947912 scopus 로고
    • Isoimmunization in pregnancy: Its possible bearing on etiology of erythroblastosis foetalis
    • Levine P, Katzin EM, Burham L. Isoimmunization in pregnancy: Its possible bearing on etiology of erythroblastosis foetalis. JAMA 1941;116:825.
    • (1941) JAMA , vol.116 , pp. 825
    • Levine, P.1    Katzin, E.M.2    Burham, L.3
  • 75
    • 0037224761 scopus 로고    scopus 로고
    • Detecting genotype combinations that increase risk for disease: Maternal-fetal genotype incompatibility test
    • Sinsheimer JS, Palmer CG, Woodward JA. Detecting genotype combinations that increase risk for disease: maternal-fetal genotype incompatibility test. Genet Epidemiol 2003;24:1-13.
    • (2003) Genet Epidemiol , vol.24 , pp. 1-13
    • Sinsheimer, J.S.1    Palmer, C.G.2    Woodward, J.A.3
  • 76
    • 33646073415 scopus 로고    scopus 로고
    • Alloimmunity to RhD in humans
    • Urbaniak SJ. Alloimmunity to RhD in humans. Transfus Clin Biol 2006;13:19-22.
    • (2006) Transfus Clin Biol , vol.13 , pp. 19-22
    • Urbaniak, S.J.1
  • 78
    • 4143069400 scopus 로고    scopus 로고
    • Analysis of the mitochondrial genome of cheetahs (Acinonyx jubatus) with neurodegenerative disease
    • Burger PA, Steinborn R, Walzer C, Petit T, Mueller M, Schwarzenberger F. Analysis of the mitochondrial genome of cheetahs (Acinonyx jubatus) with neurodegenerative disease. Gene 2004;338:111-19.
    • (2004) Gene , vol.338 , pp. 111-119
    • Burger, P.A.1    Steinborn, R.2    Walzer, C.3    Petit, T.4    Mueller, M.5    Schwarzenberger, F.6
  • 79
    • 33845577468 scopus 로고    scopus 로고
    • Genetic predisposition for preterm PROM: Results of a large candidate-gene association study of mothers and their offspring
    • (abstract)
    • Friel L, Kuivaniemi H, Gomez R, Goddard K, Nien JK, Tromp G, et al. Genetic predisposition for preterm PROM: results of a large candidate-gene association study of mothers and their offspring. Am J Obstet Gynecol 2005;6:S17 (abstract).
    • (2005) Am J Obstet Gynecol , vol.6
    • Friel, L.1    Kuivaniemi, H.2    Gomez, R.3    Goddard, K.4    Nien, J.K.5    Tromp, G.6
  • 80
    • 3442877869 scopus 로고    scopus 로고
    • A polymorphism in the promoter region of TNF and bacterial vaginosis: Preliminary evidence of gene-environment interaction in the etiology of spontaneous preterm birth
    • Macones GA, Parry S, Elkousy M, Clothier B, Ural SH, Strauss JF III. A polymorphism in the promoter region of TNF and bacterial vaginosis: preliminary evidence of gene-environment interaction in the etiology of spontaneous preterm birth. Am J Obstet Gynecol 2004;190:1504-8.
    • (2004) Am J Obstet Gynecol , vol.190 , pp. 1504-1508
    • Macones, G.A.1    Parry, S.2    Elkousy, M.3    Clothier, B.4    Ural, S.H.5    Strauss III, J.F.6
  • 81
    • 0035093939 scopus 로고    scopus 로고
    • Harvesting the fruits of the human genome
    • Harvesting the fruits of the human genome. Nat Genet 2001;27:227-8.
    • (2001) Nat Genet , vol.27 , pp. 227-228
  • 82
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap Project
    • The International HapMap Project. Nature 2003;426:789-96.
    • (2003) Nature , vol.426 , pp. 789-796
  • 83
    • 27544516082 scopus 로고    scopus 로고
    • Genome-wide definitive haplotypes determined using a collection of complete hydatidiform moles
    • Kukita Y, Miyatake K, Stokowski R, Hinds D, Higasa K, Wake N, et al. Genome-wide definitive haplotypes determined using a collection of complete hydatidiform moles. Genome Res 2005;15:1511-18.
    • (2005) Genome Res , vol.15 , pp. 1511-1518
    • Kukita, Y.1    Miyatake, K.2    Stokowski, R.3    Hinds, D.4    Higasa, K.5    Wake, N.6
  • 84
    • 0036898231 scopus 로고    scopus 로고
    • Characterizing the physical genome
    • Pollack JR, Iyer VR. Characterizing the physical genome. Nat Genet 2002;32(Suppl):515-21.
    • (2002) Nat Genet , vol.32 , Issue.SUPPL. , pp. 515-521
    • Pollack, J.R.1    Iyer, V.R.2
  • 85
    • 4544231242 scopus 로고    scopus 로고
    • Haplotype analysis and identification of genes for a complex trait: Examples from schizophrenia
    • Hennah W, Varilo T, Paunio T, Peltonen L. Haplotype analysis and identification of genes for a complex trait: examples from schizophrenia. Ann Med 2004;36:322-31.
    • (2004) Ann Med , vol.36 , pp. 322-331
    • Hennah, W.1    Varilo, T.2    Paunio, T.3    Peltonen, L.4
  • 86
    • 2642583283 scopus 로고    scopus 로고
    • Mapping complex disease loci in whole-genome association studies
    • Carlson CS, Eberle MA, Kruglyak L, Nickerson DA. Mapping complex disease loci in whole-genome association studies. Nature 2004;429:446-52.
    • (2004) Nature , vol.429 , pp. 446-452
    • Carlson, C.S.1    Eberle, M.A.2    Kruglyak, L.3    Nickerson, D.A.4
  • 87
    • 27744462212 scopus 로고    scopus 로고
    • Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk
    • Rivera A, Fisher SA, Fritsche LG, Keilhauer CN, Lichtner P, Meitinger T, et al. Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk. Hum Mol Genet 2005;14:3227-36.
    • (2005) Hum Mol Genet , vol.14 , pp. 3227-3236
    • Rivera, A.1    Fisher, S.A.2    Fritsche, L.G.3    Keilhauer, C.N.4    Lichtner, P.5    Meitinger, T.6
  • 88
    • 21044453724 scopus 로고    scopus 로고
    • A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
    • Hageman GS, Anderson DH, Johnson LV, Hancox LS, Taiber AJ, Hardisty LI, et al. A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A 2005;102:7227-32.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 7227-7232
    • Hageman, G.S.1    Anderson, D.H.2    Johnson, L.V.3    Hancox, L.S.4    Taiber, A.J.5    Hardisty, L.I.6
  • 91
    • 0016711037 scopus 로고
    • High resolution two-dimensional electrophoresis of proteins
    • O'Farrell PH. High resolution two-dimensional electrophoresis of proteins. J Biol Chem 1975;250:4007-21.
    • (1975) J Biol Chem , vol.250 , pp. 4007-4021
    • O'Farrell, P.H.1
  • 92
    • 10744231653 scopus 로고    scopus 로고
    • Identification of biologic markers of the premature rupture of fetal membranes: Proteomic approach
    • Vuadens F, Benay C, Crettaz D, Gallot D, Sapin V, Schneider P, et al. Identification of biologic markers of the premature rupture of fetal membranes: proteomic approach. Proteomics 2003;3:1521-5.
    • (2003) Proteomics , vol.3 , pp. 1521-1525
    • Vuadens, F.1    Benay, C.2    Crettaz, D.3    Gallot, D.4    Sapin, V.5    Schneider, P.6
  • 93
    • 14644398928 scopus 로고    scopus 로고
    • Proteomic analysis of preterm parturition: A novel method of identifying the patient at risk for preterm delivery
    • (abstract)
    • Buhimschi I, Christner R, Buhimschi C, Chaiworapongsa T, Romero R. Proteomic analysis of preterm parturition: a novel method of identifying the patient at risk for preterm delivery. Am J Obstet Gynecol 2002;6:S55 (abstract).
    • (2002) Am J Obstet Gynecol , vol.6
    • Buhimschi, I.1    Christner, R.2    Buhimschi, C.3    Chaiworapongsa, T.4    Romero, R.5
  • 94
    • 3242759883 scopus 로고    scopus 로고
    • Diagnosis of intra-amniotic infection by proteomic profiling and identification of novel biomarkers
    • Gravett MG, Novy MJ, Rosenfeld RG, Reddy AP, Jacob T, Turner M, et al. Diagnosis of intra-amniotic infection by proteomic profiling and identification of novel biomarkers. JAMA 2004;292:462-9.
    • (2004) JAMA , vol.292 , pp. 462-469
    • Gravett, M.G.1    Novy, M.J.2    Rosenfeld, R.G.3    Reddy, A.P.4    Jacob, T.5    Turner, M.6
  • 95
    • 29144497972 scopus 로고    scopus 로고
    • Proteomic analysis using protein chips to detect biomarkers in cervical and amniotic fluid in women with intra-amniotic inflammation
    • Ruetschi U, Rosen A, Karlsson G, Zetterberg H, Rymo L, Hagberg H, et al. Proteomic analysis using protein chips to detect biomarkers in cervical and amniotic fluid in women with intra-amniotic inflammation. J Proteome Res 2005;4:2236-42.
    • (2005) J Proteome Res , vol.4 , pp. 2236-2242
    • Ruetschi, U.1    Rosen, A.2    Karlsson, G.3    Zetterberg, H.4    Rymo, L.5    Hagberg, H.6
  • 97
    • 13844270023 scopus 로고    scopus 로고
    • Proteomic profiling of premature labor: A method to identify clinical biomarkers and mechanisms of disease
    • (abstract)
    • Romero R, Chaiworapongsa T, Gomez R, Kim YM, Edwin S, Bujold E, et al. Proteomic profiling of premature labor: a method to identify clinical biomarkers and mechanisms of disease. Am J Obstet Gynecol 2003;6(Suppl 1):S63 (abstract).
    • (2003) Am J Obstet Gynecol , vol.6 , Issue.SUPPL. 1
    • Romero, R.1    Chaiworapongsa, T.2    Gomez, R.3    Kim, Y.M.4    Edwin, S.5    Bujold, E.6
  • 98
    • 0027441704 scopus 로고
    • The diagnostic and prognostic value of amniotic fluid white blood cell count, glucose, interleukin-6, and gram stain in patients with preterm labor and intact membranes
    • Romero R, Yoon BH, Mazor M, Gomez R, Diamond MP, Kenney JS, et al. The diagnostic and prognostic value of amniotic fluid white blood cell count, glucose, interleukin-6, and gram stain in patients with preterm labor and intact membranes. Am J Obstet Gynecol 1993;169:805-16.
    • (1993) Am J Obstet Gynecol , vol.169 , pp. 805-816
    • Romero, R.1    Yoon, B.H.2    Mazor, M.3    Gomez, R.4    Diamond, M.P.5    Kenney, J.S.6
  • 99
    • 0027770942 scopus 로고
    • Amniotic fluid interleukin-6 determinations are of diagnostic and prognostic value in preterm labor
    • Romero R, Yoon BH, Kenney JS, Gomez R, Allison AC, Sehgal PB. Amniotic fluid interleukin-6 determinations are of diagnostic and prognostic value in preterm labor. Am J Reprod Immunol 1993;30:167-83.
    • (1993) Am J Reprod Immunol , vol.30 , pp. 167-183
    • Romero, R.1    Yoon, B.H.2    Kenney, J.S.3    Gomez, R.4    Allison, A.C.5    Sehgal, P.B.6
  • 100
    • 0028932937 scopus 로고
    • Amniotic fluid interleukin-6: A sensitive test for antenatal diagnosis of acute inflammatory lesions of preterm placenta and prediction of perinatal morbidity
    • Yoon BH, Romero R, Kim CJ, Jun JK, Gomez R, Choi JH, et al. Amniotic fluid interleukin-6: a sensitive test for antenatal diagnosis of acute inflammatory lesions of preterm placenta and prediction of perinatal morbidity. Am J Obstet Gynecol 1995;172:960-70.
    • (1995) Am J Obstet Gynecol , vol.172 , pp. 960-970
    • Yoon, B.H.1    Romero, R.2    Kim, C.J.3    Jun, J.K.4    Gomez, R.5    Choi, J.H.6
  • 101
    • 0030872032 scopus 로고    scopus 로고
    • Amniotic fluid inflammatory cytokines (interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha), neonatal brain white matter lesions, and cerebral palsy
    • Yoon BH, Jun JK, Romero R, Park KH, Gomez R, Choi JH, et al. Amniotic fluid inflammatory cytokines (interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha), neonatal brain white matter lesions, and cerebral palsy. Am J Obstet Gynecol 1997;177:19-26.
    • (1997) Am J Obstet Gynecol , vol.177 , pp. 19-26
    • Yoon, B.H.1    Jun, J.K.2    Romero, R.3    Park, K.H.4    Gomez, R.5    Choi, J.H.6
  • 102
    • 0030883944 scopus 로고    scopus 로고
    • High expression of tumor necrosis factor-alpha and interleukin-6 in periventricular leukomalacia
    • Yoon BH, Romero R, Kim CJ, Koo JN, Choe G, Syn HC, et al. High expression of tumor necrosis factor-alpha and interleukin-6 in periventricular leukomalacia. Am J Obstet Gynecol 1997;177:406-11.
    • (1997) Am J Obstet Gynecol , vol.177 , pp. 406-411
    • Yoon, B.H.1    Romero, R.2    Kim, C.J.3    Koo, J.N.4    Choe, G.5    Syn, H.C.6
  • 103
    • 0030694815 scopus 로고    scopus 로고
    • Amniotic fluid cytokines (interleukin-6, tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-8) and the risk for the development of bronchopulmonary dysplasia
    • Yoon BH, Romero R, Jun JK, Park KH, Park JD, Ghezzi F, et al. Amniotic fluid cytokines (interleukin-6, tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-8) and the risk for the development of bronchopulmonary dysplasia. Am J Obstet Gynecol 1997;177:825-30.
    • (1997) Am J Obstet Gynecol , vol.177 , pp. 825-830
    • Yoon, B.H.1    Romero, R.2    Jun, J.K.3    Park, K.H.4    Park, J.D.5    Ghezzi, F.6
  • 104
    • 0034037785 scopus 로고    scopus 로고
    • Fetal exposure to an intra-amniotic inflammation and the development of cerebral palsy at the age of three years
    • Yoon BH, Romero R, Park JS, Kim CJ, Kim SH, Choi JH, et al. Fetal exposure to an intra-amniotic inflammation and the development of cerebral palsy at the age of three years. Am J Obstet Gynecol 2000;182:675-81.
    • (2000) Am J Obstet Gynecol , vol.182 , pp. 675-681
    • Yoon, B.H.1    Romero, R.2    Park, J.S.3    Kim, C.J.4    Kim, S.H.5    Choi, J.H.6
  • 105
    • 33748783381 scopus 로고    scopus 로고
    • A rapid MMP-8 bedside test for the detection of intra-amniotic inflammation identifies patients at risk for imminent preterm delivery
    • Nien JK, Yoon BH, Espinoza J, Kusanovic JP, Erez O, Soto E, et al. A rapid MMP-8 bedside test for the detection of intra-amniotic inflammation identifies patients at risk for imminent preterm delivery. Am J Obstet Gynecol 2006;195:1025-30.
    • (2006) Am J Obstet Gynecol , vol.195 , pp. 1025-1030
    • Nien, J.K.1    Yoon, B.H.2    Espinoza, J.3    Kusanovic, J.P.4    Erez, O.5    Soto, E.6
  • 107
    • 0035200456 scopus 로고    scopus 로고
    • An elevated amniotic fluid matrix metalloproteinase-8 level at the time of midtrimester genetic amniocentesis is a risk factor for spontaneous preterm delivery
    • Yoon BH, Oh SY, Romero R, Shim SS, Han SY, Park JS, et al. An elevated amniotic fluid matrix metalloproteinase-8 level at the time of midtrimester genetic amniocentesis is a risk factor for spontaneous preterm delivery. Am J Obstet Gynecol 2001;185:1162-7.
    • (2001) Am J Obstet Gynecol , vol.185 , pp. 1162-1167
    • Yoon, B.H.1    Oh, S.Y.2    Romero, R.3    Shim, S.S.4    Han, S.Y.5    Park, J.S.6
  • 109
    • 0035196393 scopus 로고    scopus 로고
    • The relationship between amniotic fluid matrix metalloproteinase-8 and funisitis
    • Park JS, Romero R, Yoon BH, Moon JB, Oh SY, Han SY, et al. The relationship between amniotic fluid matrix metalloproteinase-8 and funisitis. Am J Obstet Gynecol 2001;185:1156-61.
    • (2001) Am J Obstet Gynecol , vol.185 , pp. 1156-1161
    • Park, J.S.1    Romero, R.2    Yoon, B.H.3    Moon, J.B.4    Oh, S.Y.5    Han, S.Y.6
  • 110
    • 7044265051 scopus 로고    scopus 로고
    • Clinical significance of intra-amniotic inflammation in patients with preterm premature rupture of membranes
    • Shim SS, Romero R, Hong JS, Park CW, Jun JK, Kim BI, et al. Clinical significance of intra-amniotic inflammation in patients with preterm premature rupture of membranes. Am J Obstet Gynecol 2004;191:1339-45.
    • (2004) Am J Obstet Gynecol , vol.191 , pp. 1339-1345
    • Shim, S.S.1    Romero, R.2    Hong, J.S.3    Park, C.W.4    Jun, J.K.5    Kim, B.I.6
  • 111
    • 33646086927 scopus 로고    scopus 로고
    • Metabolomics in premature labor: A novel approach to identify patients at risk for preterm delivery
    • (abstract)
    • Romero R, Gomez R, Nien JK, Yoon BH, Luo R, Beecher C, et al. Metabolomics in premature labor: a novel approach to identify patients at risk for preterm delivery. Am J Obstet Gynecol 2004;6(Suppl 1):S2 (abstract).
    • (2004) Am J Obstet Gynecol , vol.6 , Issue.SUPPL. 1
    • Romero, R.1    Gomez, R.2    Nien, J.K.3    Yoon, B.H.4    Luo, R.5    Beecher, C.6
  • 112
    • 0346992344 scopus 로고    scopus 로고
    • Point-of-care testing: An introduction
    • Gutierres SL, Welty TE. Point-of-care testing: an introduction. Ann Pharmacother 2004;38:119-25.
    • (2004) Ann Pharmacother , vol.38 , pp. 119-125
    • Gutierres, S.L.1    Welty, T.E.2
  • 114
    • 0037252535 scopus 로고    scopus 로고
    • Dexamethasone or interleukin-10 blocks interleukin-1beta-induced uterine contractions in pregnant rhesus monkeys
    • Sadowsky DW, Novy MJ, Witkin SS, Gravett MG. Dexamethasone or interleukin-10 blocks interleukin-1beta-induced uterine contractions in pregnant rhesus monkeys. Am J Obstet Gynecol 2003;188:252-63.
    • (2003) Am J Obstet Gynecol , vol.188 , pp. 252-263
    • Sadowsky, D.W.1    Novy, M.J.2    Witkin, S.S.3    Gravett, M.G.4
  • 115
    • 33748802022 scopus 로고    scopus 로고
    • Maternal N-acetylcysteine suppresses fetal inflammatory cytokine responses to maternal lipopolysaccharide
    • Beloosesky R, Gayle DA, Ross MG. Maternal N-acetylcysteine suppresses fetal inflammatory cytokine responses to maternal lipopolysaccharide. Am J Obstet Gynecol 2006;195:1053-7.
    • (2006) Am J Obstet Gynecol , vol.195 , pp. 1053-1057
    • Beloosesky, R.1    Gayle, D.A.2    Ross, M.G.3
  • 117
    • 0028806048 scopus 로고
    • Quantitative monitoring of gene expression patterns with a complementary DNA microarray
    • Schena M, Shalon D, Davis RW, Brown PO. Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 1995;270:467-70.
    • (1995) Science , vol.270 , pp. 467-470
    • Schena, M.1    Shalon, D.2    Davis, R.W.3    Brown, P.O.4
  • 121
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
    • Alizadeh AA, Eisen MB, Davis RE, Ma C, Lossos IS, Rosenwald A, et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 2000;403:503-11.
    • (2000) Nature , vol.403 , pp. 503-511
    • Alizadeh, A.A.1    Eisen, M.B.2    Davis, R.E.3    Ma, C.4    Lossos, I.S.5    Rosenwald, A.6
  • 122
    • 0030010495 scopus 로고
    • Quantitative polymerase chain reaction for determination of different oxytocin receptor mRNA expression in non-pregnant and pregnant uterine tissue
    • Helmer H, Dobianer K, Koukal T, Husslein P. Quantitative polymerase chain reaction for determination of different oxytocin receptor mRNA expression in non-pregnant and pregnant uterine tissue. Adv Exp Med Biol 1995;395:487-8.
    • (1995) Adv Exp Med Biol , vol.395 , pp. 487-488
    • Helmer, H.1    Dobianer, K.2    Koukal, T.3    Husslein, P.4
  • 123
    • 0030820358 scopus 로고    scopus 로고
    • Identification of gestationally regulated genes in rat myometrium by use of messenger ribonucleic acid differential display
    • Chien EK, Tokuyama Y, Rouard M, Phillippe M, Bell GI. Identification of gestationally regulated genes in rat myometrium by use of messenger ribonucleic acid differential display. Am J Obstet Gynecol 1997;177:645-52.
    • (1997) Am J Obstet Gynecol , vol.177 , pp. 645-652
    • Chien, E.K.1    Tokuyama, Y.2    Rouard, M.3    Phillippe, M.4    Bell, G.I.5
  • 124
    • 0033306861 scopus 로고    scopus 로고
    • The differential expression of myometrial connexin-43, cyclooxygenase-1 and -2, and Gs alpha proteins in the upper and lower segments of the human uterus during pregnancy and labor
    • Sparey C, Robson SC, Bailey J, Lyall F, Europe-Finner GN. The differential expression of myometrial connexin-43, cyclooxygenase-1 and -2, and Gs alpha proteins in the upper and lower segments of the human uterus during pregnancy and labor. J Clin Endocrinol Metab 1999;84:1705-10.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 1705-1710
    • Sparey, C.1    Robson, S.C.2    Bailey, J.3    Lyall, F.4    Europe-Finner, G.N.5
  • 125
    • 0033306864 scopus 로고    scopus 로고
    • Suppression subtractive hybridization identified a marked increase in thrombospondin-1 associated with parturition in pregnant sheep myometrium
    • Wu WX, Zhang Q, Ma XH, Unno N, Nathanielsz PW. Suppression subtractive hybridization identified a marked increase in thrombospondin-1 associated with parturition in pregnant sheep myometrium. Endocrinology 1999;140:2364-71.
    • (1999) Endocrinology , vol.140 , pp. 2364-2371
    • Wu, W.X.1    Zhang, Q.2    Ma, X.H.3    Unno, N.4    Nathanielsz, P.W.5
  • 126
    • 0033709493 scopus 로고    scopus 로고
    • Endocrine and paracrine regulation of birth at term and preterm
    • Challis JRG, Matthews SG, Gibb W, Lye SJ. Endocrine and paracrine regulation of birth at term and preterm. Endocr Rev 2000;21:514-50.
    • (2000) Endocr Rev , vol.21 , pp. 514-550
    • Challis, J.R.G.1    Matthews, S.G.2    Gibb, W.3    Lye, S.J.4
  • 127
    • 17544368384 scopus 로고    scopus 로고
    • Characterization of decorin mRNA in pregnant intrauterine tissues of the ewe and regulation by steroids
    • Wu WX, Zhang Q, Unno N, Derks JB, Nathanielsz PW. Characterization of decorin mRNA in pregnant intrauterine tissues of the ewe and regulation by steroids. Am J Physiol Cell Physiol 2000;278:C199-206.
    • (2000) Am J Physiol Cell Physiol , vol.278
    • Wu, W.X.1    Zhang, Q.2    Unno, N.3    Derks, J.B.4    Nathanielsz, P.W.5
  • 129
    • 12444308935 scopus 로고    scopus 로고
    • A functional genomic study to identify differential gene expression in the preterm and term human myometrium
    • Charpigny G, Leroy MJ, Breuiller-Fouche M, Tanfin Z, Mhaouty-Kodja S, Robin P, et al. A functional genomic study to identify differential gene expression in the preterm and term human myometrium. Biol Reprod 2003;68:2289-96.
    • (2003) Biol Reprod , vol.68 , pp. 2289-2296
    • Charpigny, G.1    Leroy, M.J.2    Breuiller-Fouche, M.3    Tanfin, Z.4    Mhaouty-Kodja, S.5    Robin, P.6
  • 131
    • 23844473548 scopus 로고    scopus 로고
    • The use of cDNA microarray to identify differentially expressed labor-associated genes within the human myometrium during labor
    • Esplin MS, Fausett MB, Peltier MR, Hamblin S, Silver RM, Branch DW, et al. The use of cDNA microarray to identify differentially expressed labor-associated genes within the human myometrium during labor. Am J Obstet Gynecol 2005;193:404-13.
    • (2005) Am J Obstet Gynecol , vol.193 , pp. 404-413
    • Esplin, M.S.1    Fausett, M.B.2    Peltier, M.R.3    Hamblin, S.4    Silver, R.M.5    Branch, D.W.6
  • 132
    • 23944518451 scopus 로고    scopus 로고
    • The transcription factor Ets-1 is expressed in human amniochorionic membranes and is up-regulated in term and preterm premature rupture of membranes
    • Michaelis SA, Okuducu AF, Sarioglu NM, von Deimling A, Dudenhausen JW. The transcription factor Ets-1 is expressed in human amniochorionic membranes and is up-regulated in term and preterm premature rupture of membranes. J Perinat Med 2005;33:314-19.
    • (2005) J Perinat Med , vol.33 , pp. 314-319
    • Michaelis, S.A.1    Okuducu, A.F.2    Sarioglu, N.M.3    Von Deimling, A.4    Dudenhausen, J.W.5
  • 133
    • 33845566932 scopus 로고    scopus 로고
    • Transcriptional regulation of labour-associated genes
    • Norman J, Greer I, editors. Cambridge, UK: Cambridge University Press
    • Lindstrom T, Loudon J, Bennett P. Transcriptional regulation of labour-associated genes. In: Norman J, Greer I, editors. Preterm Labour. Managing Risk in a Clinical Practice. Cambridge, UK: Cambridge University Press; 2005. pp. 76-108.
    • (2005) Preterm Labour. Managing Risk in a Clinical Practice , pp. 76-108
    • Lindstrom, T.1    Loudon, J.2    Bennett, P.3
  • 136
    • 27144472873 scopus 로고    scopus 로고
    • Transgene insertion on mouse chromosome 6 impairs function of the uterine cervix and causes failure of parturition
    • Word RA, Landrum CP, Timmons BC, Young SG, Mahendroo MS. Transgene insertion on mouse chromosome 6 impairs function of the uterine cervix and causes failure of parturition. Biol Reprod 2005;73:1046-56.
    • (2005) Biol Reprod , vol.73 , pp. 1046-1056
    • Word, R.A.1    Landrum, C.P.2    Timmons, B.C.3    Young, S.G.4    Mahendroo, M.S.5
  • 137
    • 85047682792 scopus 로고    scopus 로고
    • Functional genomics and proteomics in term and preterm parturition
    • Romero R, Kuivaniemi H, Tromp G. Functional genomics and proteomics in term and preterm parturition. J Clin Endocrinol Metab 2002;87:2431-4.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2431-2434
    • Romero, R.1    Kuivaniemi, H.2    Tromp, G.3
  • 139
    • 21744443814 scopus 로고    scopus 로고
    • Genomics: New technology for obstetrics
    • Wilson RD. Genomics: new technology for obstetrics. J Obstet Gynaecol Can 2005;27:63-75.
    • (2005) J Obstet Gynaecol Can , vol.27 , pp. 63-75
    • Wilson, R.D.1
  • 140
    • 33746683125 scopus 로고    scopus 로고
    • Analysis of microarray experiments of gene expression profiling
    • Tarca AL, Romero R, Draghici S. Analysis of microarray experiments of gene expression profiling. Am J Obstet Gynecol 2006;195:373-88.
    • (2006) Am J Obstet Gynecol , vol.195 , pp. 373-388
    • Tarca, A.L.1    Romero, R.2    Draghici, S.3
  • 141
    • 33746676270 scopus 로고    scopus 로고
    • High-dimensional biology in obstetrics and gynecology: Functional genomics in microarray studies
    • Romero R, Tromp G. High-dimensional biology in obstetrics and gynecology: functional genomics in microarray studies. Am J Obstet Gynecol 2006;195:360-3.
    • (2006) Am J Obstet Gynecol , vol.195 , pp. 360-363
    • Romero, R.1    Tromp, G.2
  • 142
    • 33746537117 scopus 로고    scopus 로고
    • Microarray technology in obstetrics and gynecology: A guide for clinicians
    • Ward K. Microarray technology in obstetrics and gynecology: a guide for clinicians. Am J Obstet Gynecol 2006;195:364-72.
    • (2006) Am J Obstet Gynecol , vol.195 , pp. 364-372
    • Ward, K.1
  • 143
    • 33646781909 scopus 로고    scopus 로고
    • Identification of interactive gene networks: A novel approach in gene array profiling of myometrial events during guinea pig pregnancy
    • Mason CW, Swaan PW, Weiner CP. Identification of interactive gene networks: a novel approach in gene array profiling of myometrial events during guinea pig pregnancy. Am J Obstet Gynecol 2006;194:1513-23.
    • (2006) Am J Obstet Gynecol , vol.194 , pp. 1513-1523
    • Mason, C.W.1    Swaan, P.W.2    Weiner, C.P.3
  • 144
    • 0033674306 scopus 로고    scopus 로고
    • Application of a functional genomics approach to identify differentially expressed genes in human myometrium during pregnancy and labour
    • Aguan K, Carvajal JA, Thompson LP, Weiner CP. Application of a functional genomics approach to identify differentially expressed genes in human myometrium during pregnancy and labour. Mol Hum Reprod 2000;6:1141-5.
    • (2000) Mol Hum Reprod , vol.6 , pp. 1141-1145
    • Aguan, K.1    Carvajal, J.A.2    Thompson, L.P.3    Weiner, C.P.4
  • 145
    • 0036078512 scopus 로고    scopus 로고
    • Human myometrial genes are differentially expressed in labor: A suppression subtractive hybridization study
    • Chan EC, Fraser S, Yin S, Yeo G, Kwek K, Fairclough RJ, et al. Human myometrial genes are differentially expressed in labor: a suppression subtractive hybridization study. J Clin Endocrinol Metab 2002;87:2435-41.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2435-2441
    • Chan, E.C.1    Fraser, S.2    Yin, S.3    Yeo, G.4    Kwek, K.5    Fairclough, R.J.6
  • 146
    • 7044226549 scopus 로고    scopus 로고
    • Genome-wide expression profiling of fetal membranes reveals a deficient expression of proteinase inhibitor 3 in premature rupture of membranes
    • Tromp G, Kuivaniemi H, Romero R, Chaiworapongsa T, Kim YM, Kim MR, et al. Genome-wide expression profiling of fetal membranes reveals a deficient expression of proteinase inhibitor 3 in premature rupture of membranes. Am J Obstet Gynecol 2004;191:1331-8.
    • (2004) Am J Obstet Gynecol , vol.191 , pp. 1331-1338
    • Tromp, G.1    Kuivaniemi, H.2    Romero, R.3    Chaiworapongsa, T.4    Kim, Y.M.5    Kim, M.R.6
  • 147
    • 0036774793 scopus 로고    scopus 로고
    • Neutrophil elastase and secretory leukocyte protease inhibitor in prelabor rupture of membranes, parturition and intra-amniotic infection
    • Helmig BR, Romero R, Espinoza J, Chaiworapongsa T, Bujold E, Gomez R, et al. Neutrophil elastase and secretory leukocyte protease inhibitor in prelabor rupture of membranes, parturition and intra-amniotic infection. J Matern Fetal Neonatal Med 2002;12:237-46.
    • (2002) J Matern Fetal Neonatal Med , vol.12 , pp. 237-246
    • Helmig, B.R.1    Romero, R.2    Espinoza, J.3    Chaiworapongsa, T.4    Bujold, E.5    Gomez, R.6
  • 148
    • 0032782087 scopus 로고    scopus 로고
    • Genes upregulated in human fetal membranes by infection or labor
    • Tashima LS, Millar LK, Bryant-Greenwood GD. Genes upregulated in human fetal membranes by infection or labor. Obstet Gynecol 1999;94:441-9.
    • (1999) Obstet Gynecol , vol.94 , pp. 441-449
    • Tashima, L.S.1    Millar, L.K.2    Bryant-Greenwood, G.D.3
  • 149
    • 33746479025 scopus 로고    scopus 로고
    • Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature
    • Haddad R, Tromp G, Kuivaniemi H, Chaiworapongsa T, Kim YM, Mazor M, et al. Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature. Am J Obstet Gynecol 2006;195:394. e1-24.
    • (2006) Am J Obstet Gynecol , vol.195
    • Haddad, R.1    Tromp, G.2    Kuivaniemi, H.3    Chaiworapongsa, T.4    Kim, Y.M.5    Mazor, M.6
  • 150
    • 33845575535 scopus 로고    scopus 로고
    • Inflammatory aetiology of human myometrial activation tested using directed graphs
    • Bisits AM, Smith R, Mesiano S, Yeo G, Kwek K, MacIntyre D, et al. Inflammatory aetiology of human myometrial activation tested using directed graphs. PLoS Comput Biol 2005;1:132-6.
    • (2005) PLoS Comput Biol , vol.1 , pp. 132-136
    • Bisits, A.M.1    Smith, R.2    Mesiano, S.3    Yeo, G.4    Kwek, K.5    MacIntyre, D.6
  • 151
    • 33747894504 scopus 로고    scopus 로고
    • The transcriptome of the uterine cervix before and after spontaneous term parturition
    • Hassan SS, Romero R, Haddad R, Hendler I, Khalek N, Tromp G, et al. The transcriptome of the uterine cervix before and after spontaneous term parturition. Am J Obstet Gynecol 2006;195:778-86.
    • (2006) Am J Obstet Gynecol , vol.195 , pp. 778-786
    • Hassan, S.S.1    Romero, R.2    Haddad, R.3    Hendler, I.4    Khalek, N.5    Tromp, G.6
  • 152
    • 33745632044 scopus 로고    scopus 로고
    • Labor-associated gene expression in the human uterine fundus, lower segment, and cervix
    • Bukowski R, Hankins GD, Saade GR, Anderson GD, Thornton S. Labor-associated gene expression in the human uterine fundus, lower segment, and cervix. PLoS Med 2006;3:e169.
    • (2006) PLoS Med , vol.3
    • Bukowski, R.1    Hankins, G.D.2    Saade, G.R.3    Anderson, G.D.4    Thornton, S.5
  • 153
    • 33745605526 scopus 로고    scopus 로고
    • Insights into the physiology of childbirth using transcriptomics
    • Romero R, Tarca AL, Tromp G. Insights into the physiology of childbirth using transcriptomics. PLoS Med 2006;3:e276.
    • (2006) PLoS Med , vol.3
    • Romero, R.1    Tarca, A.L.2    Tromp, G.3
  • 154
    • 0034822070 scopus 로고    scopus 로고
    • A high-throughput study of gene expression in preterm labor with a subtractive microarray approach
    • Muhle RA, Pavlidis P, Grundy WN, Hirsch E. A high-throughput study of gene expression in preterm labor with a subtractive microarray approach. Am J Obstet Gynecol 2001;185:716-24.
    • (2001) Am J Obstet Gynecol , vol.185 , pp. 716-724
    • Muhle, R.A.1    Pavlidis, P.2    Grundy, W.N.3    Hirsch, E.4
  • 155
    • 15244343466 scopus 로고    scopus 로고
    • The molecular pathophysiology of bacterially induced preterm labor: Insights from themurine model
    • Hirsch E, Wang H. The molecular pathophysiology of bacterially induced preterm labor: insights from themurine model. J Soc Gynecol Investig 2005;12:145-55.
    • (2005) J Soc Gynecol Investig , vol.12 , pp. 145-155
    • Hirsch, E.1    Wang, H.2
  • 156
    • 33748172474 scopus 로고    scopus 로고
    • Uterine transcriptomes of bacteria-induced and ovariectomy-induced preterm labor in mice are characterized by differential expression of arachidonate metabolism genes
    • Haddad R, Gould BR, Romero R, Tromp G, Farookhi R, Edwin SS, et al. Uterine transcriptomes of bacteria-induced and ovariectomy-induced preterm labor in mice are characterized by differential expression of arachidonate metabolism genes. Am J Obstet Gynecol 2006;195:822-8.
    • (2006) Am J Obstet Gynecol , vol.195 , pp. 822-828
    • Haddad, R.1    Gould, B.R.2    Romero, R.3    Tromp, G.4    Farookhi, R.5    Edwin, S.S.6
  • 157
    • 33845572552 scopus 로고    scopus 로고
    • Identification of a gene expression signature in leukocytes that predicts preterm delivery in women with threatened preterm labour
    • (abstract)
    • Pennell CE, Oldenhof AD, Perkins JE, Dunk CE, Keunen J, Tan P, et al. Identification of a gene expression signature in leukocytes that predicts preterm delivery in women with threatened preterm labour. J Soc Gynecol Investig 2006;2(Suppl):175A (abstract).
    • (2006) J Soc Gynecol Investig , vol.2 , Issue.SUPPL.
    • Pennell, C.E.1    Oldenhof, A.D.2    Perkins, J.E.3    Dunk, C.E.4    Keunen, J.5    Tan, P.6
  • 159
    • 33646380353 scopus 로고    scopus 로고
    • A bioinformatician's view of the metabolome
    • Nobeli I, Thornton JM. A bioinformatician's view of the metabolome. Bioessays 2006;28:534-45.
    • (2006) Bioessays , vol.28 , pp. 534-545
    • Nobeli, I.1    Thornton, J.M.2
  • 160
    • 29244475955 scopus 로고    scopus 로고
    • Metabolomic analysis of molecular species of phospholipids from normotensive and preeclamptic human placenta electrospray ionization mass spectrometry
    • Jain S, Jayasimhulu K, Clark JF. Metabolomic analysis of molecular species of phospholipids from normotensive and preeclamptic human placenta electrospray ionization mass spectrometry. Front Biosci 2004;9:3167-75.
    • (2004) Front Biosci , vol.9 , pp. 3167-3175
    • Jain, S.1    Jayasimhulu, K.2    Clark, J.F.3
  • 161
    • 30544454201 scopus 로고    scopus 로고
    • Metabolomics reviewed: A new "omics" platform technology for systems biology and implications for natural products research
    • Rochfort S. Metabolomics reviewed: a new "omics" platform technology for systems biology and implications for natural products research. J Nat Prod 2005;68:1813-20.
    • (2005) J Nat Prod , vol.68 , pp. 1813-1820
    • Rochfort, S.1
  • 162
    • 0038699591 scopus 로고    scopus 로고
    • High-throughput classification of yeast mutants for functional genomics using metabolic footprinting
    • Allen J, Davey HM, Broadhurst D, Heald JK, Rowland JJ, Oliver SG, et al. High-throughput classification of yeast mutants for functional genomics using metabolic footprinting. Nat Biotechnol 2003;21:692-6.
    • (2003) Nat Biotechnol , vol.21 , pp. 692-696
    • Allen, J.1    Davey, H.M.2    Broadhurst, D.3    Heald, J.K.4    Rowland, J.J.5    Oliver, S.G.6
  • 163
    • 26944471174 scopus 로고    scopus 로고
    • The next wave in metabolome analysis
    • Nielsen J, Oliver S. The next wave in metabolome analysis. Trends Biotechnol 2005;23:544-6.
    • (2005) Trends Biotechnol , vol.23 , pp. 544-546
    • Nielsen, J.1    Oliver, S.2
  • 164
    • 0035160371 scopus 로고    scopus 로고
    • A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations
    • Raamsdonk LM, Teusink B, Broadhurst D, Zhang N, Hayes A, Walsh MC, et al. A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations. Nat Biotechnol 2001;19:45-50.
    • (2001) Nat Biotechnol , vol.19 , pp. 45-50
    • Raamsdonk, L.M.1    Teusink, B.2    Broadhurst, D.3    Zhang, N.4    Hayes, A.5    Walsh, M.C.6
  • 165
    • 2442647715 scopus 로고    scopus 로고
    • Differential metabolic networks unravel the effects of silent plant phenotypes
    • Weckwerth W, Loureiro ME, Wenzel K, Fiehn O. Differential metabolic networks unravel the effects of silent plant phenotypes. Proc Natl Acad Sci U S A 2004;101:7809-14.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 7809-7814
    • Weckwerth, W.1    Loureiro, M.E.2    Wenzel, K.3    Fiehn, O.4
  • 167
    • 0031781727 scopus 로고    scopus 로고
    • Rapid identification of urinary tract infection bacteria using hyperspectral whole-organism fingerprinting and artificial neural networks
    • Goodacre R, Timmins EM, Burton R, Kaderbhai N, Woodward AM, Kell DB, et al. Rapid identification of urinary tract infection bacteria using hyperspectral whole-organism fingerprinting and artificial neural networks. Microbiology 1998;144:1157-70.
    • (1998) Microbiology , vol.144 , pp. 1157-1170
    • Goodacre, R.1    Timmins, E.M.2    Burton, R.3    Kaderbhai, N.4    Woodward, A.M.5    Kell, D.B.6
  • 168
    • 4644301892 scopus 로고    scopus 로고
    • Raman spectroscopy for whole organism and tissue profiling
    • Harrigan GG, Goodacre R, editors. Norwell, MA: Kluwer Academic Publishers
    • Clarke S, Goodacre R. Raman spectroscopy for whole organism and tissue profiling. In: Harrigan GG, Goodacre R, editors. Metabolic Pro-filing. Its Role in Biomarker Discovery and Gene Function Analysis. Norwell, MA: Kluwer Academic Publishers; 2003. pp. 95-110.
    • (2003) Metabolic Pro-filing. Its Role in Biomarker Discovery and Gene Function Analysis , pp. 95-110
    • Clarke, S.1    Goodacre, R.2
  • 169
    • 0035167680 scopus 로고    scopus 로고
    • Use of direct-infusion electrospray mass spectrometry to guide empirical development of improved conditions for expression of secondary metabolites from actinomycetes
    • Zahn JA, Higgs RE, Hilton MD. Use of direct-infusion electrospray mass spectrometry to guide empirical development of improved conditions for expression of secondary metabolites from actinomycetes. Appl Environ Microbiol 2001;67:377-86.
    • (2001) Appl Environ Microbiol , vol.67 , pp. 377-386
    • Zahn, J.A.1    Higgs, R.E.2    Hilton, M.D.3
  • 172
    • 0033569641 scopus 로고    scopus 로고
    • Epigenetics: Regulation through repression
    • Wolffe AP, Matzke MA. Epigenetics: regulation through repression. Science 1999;286:481-6.
    • (1999) Science , vol.286 , pp. 481-486
    • Wolffe, A.P.1    Matzke, M.A.2
  • 173
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
    • Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 2003;33(Suppl):245-54.
    • (2003) Nat Genet , vol.33 , Issue.SUPPL. , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 175
    • 0036733675 scopus 로고    scopus 로고
    • Chromatin modification and epigenetic reprogramming in mammalian development
    • Li E. Chromatin modification and epigenetic reprogramming in mammalian development. Nat Rev Genet 2002;3:662-73.
    • (2002) Nat Rev Genet , vol.3 , pp. 662-673
    • Li, E.1
  • 177
    • 0029126403 scopus 로고
    • DNA methylation in early development
    • Razin A, Shemer R. DNA methylation in early development. Hum Mol Genet 1995;4:1751-5.
    • (1995) Hum Mol Genet , vol.4 , pp. 1751-1755
    • Razin, A.1    Shemer, R.2
  • 178
    • 0022540321 scopus 로고
    • CpG-rich islands and the function of DNA methylation
    • Bird AP. CpG-rich islands and the function of DNA methylation. Nature 1986;321:209-13.
    • (1986) Nature , vol.321 , pp. 209-213
    • Bird, A.P.1
  • 179
    • 33646793302 scopus 로고    scopus 로고
    • Epigenetics, evolution, endocrine disruption, health, and disease
    • Crews D, McLachlan JA. Epigenetics, evolution, endocrine disruption, health, and disease. Endocrinology 2006;147:S4-10.
    • (2006) Endocrinology , vol.147
    • Crews, D.1    McLachlan, J.A.2
  • 180
    • 0347123629 scopus 로고    scopus 로고
    • Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases
    • Waterland RA, Jirtle RL. Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases. Nutrition 2004;20:63-8.
    • (2004) Nutrition , vol.20 , pp. 63-68
    • Waterland, R.A.1    Jirtle, R.L.2
  • 181
    • 0036403334 scopus 로고    scopus 로고
    • Genetic effects of methylation diets
    • Van den Veyver IB. Genetic effects of methylation diets. Annu Rev Nutr 2002;22:255-82.
    • (2002) Annu Rev Nutr , vol.22 , pp. 255-282
    • Van Den Veyver, I.B.1
  • 182
    • 0031873353 scopus 로고    scopus 로고
    • Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice
    • Wolff GL, Kodell RL, Moore SR, Cooney CA. Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice. FASEB J 1998;12:949-57.
    • (1998) FASEB J , vol.12 , pp. 949-957
    • Wolff, G.L.1    Kodell, R.L.2    Moore, S.R.3    Cooney, C.A.4
  • 185
    • 15744388471 scopus 로고    scopus 로고
    • Common dihydrofolate reductase 19-base pair deletion allele: A novel risk factor for preterm delivery
    • Johnson WG, Scholl TO, Spychala JR, Buyske S, Stenroos ES, Chen X. Common dihydrofolate reductase 19-base pair deletion allele: a novel risk factor for preterm delivery. Am J Clin Nutr 2005;81:664-8.
    • (2005) Am J Clin Nutr , vol.81 , pp. 664-668
    • Johnson, W.G.1    Scholl, T.O.2    Spychala, J.R.3    Buyske, S.4    Stenroos, E.S.5    Chen, X.6
  • 186
    • 0027258289 scopus 로고
    • Low zinc intake during pregnancy: Its association with preterm and very preterm delivery
    • Scholl TO, Hediger ML, Schall JI, Fischer RL, Khoo CS. Low zinc intake during pregnancy: its association with preterm and very preterm delivery. Am J Epidemiol 1993;137:1115-24.
    • (1993) Am J Epidemiol , vol.137 , pp. 1115-1124
    • Scholl, T.O.1    Hediger, M.L.2    Schall, J.I.3    Fischer, R.L.4    Khoo, C.S.5
  • 188
    • 0032843860 scopus 로고    scopus 로고
    • The nuclear transcription factor NF-kappaB mediates interleukin-1beta- induced expression of cyclooxygenase-2 in human myometrial cells
    • Belt AR, Baldassare JJ, Molnar M, Romero R, Hertelendy F. The nuclear transcription factor NF-kappaB mediates interleukin-1beta-induced expression of cyclooxygenase-2 in human myometrial cells. Am J Obstet Gynecol 1999;181:359-66.
    • (1999) Am J Obstet Gynecol , vol.181 , pp. 359-366
    • Belt, A.R.1    Baldassare, J.J.2    Molnar, M.3    Romero, R.4    Hertelendy, F.5
  • 189
    • 2342451864 scopus 로고    scopus 로고
    • Premature labor. Resetting pregnancy's clock
    • Wickelgren I. Premature labor. Resetting pregnancy's clock. Science 2004;304:666-8.
    • (2004) Science , vol.304 , pp. 666-668
    • Wickelgren, I.1
  • 190
    • 2442419531 scopus 로고    scopus 로고
    • Regulation of phospholipase isozymes by nuclear factor-kappaB in human gestational tissues in vitro
    • Lappas M, Permezel M, Georgiou HM, Rice GE. Regulation of phospholipase isozymes by nuclear factor-kappaB in human gestational tissues in vitro. J Clin Endocrinol Metab 2004;89:2365-72.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2365-2372
    • Lappas, M.1    Permezel, M.2    Georgiou, H.M.3    Rice, G.E.4
  • 191
    • 27844554853 scopus 로고    scopus 로고
    • The role of nuclear factor kappa B in human labour
    • Lindstrom TM, Bennett PR. The role of nuclear factor kappa B in human labour. Reproduction 2005;130:569-81.
    • (2005) Reproduction , vol.130 , pp. 569-581
    • Lindstrom, T.M.1    Bennett, P.R.2
  • 192
    • 18044377611 scopus 로고    scopus 로고
    • New insights into the molecular endocrinology of parturition
    • Mendelson CR, Condon JC. New insights into the molecular endocrinology of parturition. J Steroid Biochem Mol Biol 2005;93:113-19.
    • (2005) J Steroid Biochem Mol Biol , vol.93 , pp. 113-119
    • Mendelson, C.R.1    Condon, J.C.2
  • 193
    • 23844555532 scopus 로고    scopus 로고
    • Modulation of cytokine-induced cyclooxygenase 2 expression by PPARG ligands through NFkappaB signal disruption in human WISH and amnion cells
    • Ackerman WE, Zhang XL, Rovin BH, Kniss DA. Modulation of cytokine-induced cyclooxygenase 2 expression by PPARG ligands through NFkappaB signal disruption in human WISH and amnion cells. Biol Reprod 2005;73:527-35.
    • (2005) Biol Reprod , vol.73 , pp. 527-535
    • Ackerman, W.E.1    Zhang, X.L.2    Rovin, B.H.3    Kniss, D.A.4
  • 194
    • 21244449233 scopus 로고    scopus 로고
    • 15-Deoxy-{delta}12,14-prostaglandin j2 inhibits interleukin-1{beta}- induced nuclear factor-{kappa}b in human amnion and myometrial cells: Mechanisms and implications
    • Lindstrom TM, Bennett PR. 15-Deoxy-{delta}12,14-prostaglandin j2 inhibits interleukin-1{beta}-induced nuclear factor-{kappa}b in human amnion and myometrial cells: mechanisms and implications. J Clin Endocrinol Metab 2005;90:3534-43.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 3534-3543
    • Lindstrom, T.M.1    Bennett, P.R.2
  • 195
    • 33845582494 scopus 로고    scopus 로고
    • Upregulation of the progesterone receptor (PR)-C isoform in laboring myometrium by activation of NF-kB may contribute to the onset of labor through inhibition of PR function
    • (abstract)
    • Condon JC, Hardy DB, Mendelson CR. Upregulation of the progesterone receptor (PR)-C isoform in laboring myometrium by activation of NF-kB may contribute to the onset of labor through inhibition of PR function. J Soc Gynecol Investig 2006;2:65A (abstract).
    • (2006) J Soc Gynecol Investig , vol.2
    • Condon, J.C.1    Hardy, D.B.2    Mendelson, C.R.3
  • 196
    • 0031877467 scopus 로고    scopus 로고
    • A fetal systemic inflammatory response is followed by the spontaneous onset of preterm parturition
    • Romero R, Gomez R, Ghezzi F, Yoon BH, Mazor M, Edwin SS, et al. A fetal systemic inflammatory response is followed by the spontaneous onset of preterm parturition. Am J Obstet Gynecol 1998;179:186-93.
    • (1998) Am J Obstet Gynecol , vol.179 , pp. 186-193
    • Romero, R.1    Gomez, R.2    Ghezzi, F.3    Yoon, B.H.4    Mazor, M.5    Edwin, S.S.6
  • 198
    • 19644389279 scopus 로고    scopus 로고
    • Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation
    • Hodge DR, Peng B, Cherry JC, Hurt EM, Fox SD, Kelley JA, et al. Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation. Cancer Res 2005;65:4673-82.
    • (2005) Cancer Res , vol.65 , pp. 4673-4682
    • Hodge, D.R.1    Peng, B.2    Cherry, J.C.3    Hurt, E.M.4    Fox, S.D.5    Kelley, J.A.6
  • 199
    • 14244259066 scopus 로고    scopus 로고
    • Epigenetic silencing of the human nucleotide excision repair gene, hHR23B, in interleukin-6-responsive multiple myeloma KAS-6/1 cells
    • Peng B, Hodge DR, Thomas SB, Cherry JM, Munroe DJ, Pompeia C, et al. Epigenetic silencing of the human nucleotide excision repair gene, hHR23B, in interleukin-6-responsive multiple myeloma KAS-6/1 cells. J Biol Chem 2005;280:4182-7.
    • (2005) J Biol Chem , vol.280 , pp. 4182-4187
    • Peng, B.1    Hodge, D.R.2    Thomas, S.B.3    Cherry, J.M.4    Munroe, D.J.5    Pompeia, C.6
  • 200
    • 2442674336 scopus 로고    scopus 로고
    • Microarray analysis of epigenetic silencing of gene expression in the KAS-6/1 multiple myeloma cell line
    • Pompeia C, Hodge DR, Plass C, Wu YZ, Marquez VE, Kelley JA, et al. Microarray analysis of epigenetic silencing of gene expression in the KAS-6/1 multiple myeloma cell line. Cancer Res 2004;64:3465-73.
    • (2004) Cancer Res , vol.64 , pp. 3465-3473
    • Pompeia, C.1    Hodge, D.R.2    Plass, C.3    Wu, Y.Z.4    Marquez, V.E.5    Kelley, J.A.6
  • 201
    • 30544454697 scopus 로고    scopus 로고
    • The polycomb group protein enhancer of zeste homolog 2 (EZH 2) is an oncogene that influences myeloma cell growth and the mutant ras phenotype
    • Croonquist PA, Van NB. The polycomb group protein enhancer of zeste homolog 2 (EZH 2) is an oncogene that influences myeloma cell growth and the mutant ras phenotype. Oncogene 2005;24:6269-80.
    • (2005) Oncogene , vol.24 , pp. 6269-6280
    • Croonquist, P.A.1    Van, N.B.2
  • 203
    • 0041923549 scopus 로고    scopus 로고
    • A decline in the levels of progesterone receptor coactivators in the pregnant uterus at term may antagonize progesterone receptor function and contribute to the initiation of parturition
    • Condon JC, Jeyasuria P, Faust JM, Wilson JW, Mendelson CR. A decline in the levels of progesterone receptor coactivators in the pregnant uterus at term may antagonize progesterone receptor function and contribute to the initiation of parturition. Proc Natl Acad Sci U S A 2003;100:9518-23.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9518-9523
    • Condon, J.C.1    Jeyasuria, P.2    Faust, J.M.3    Wilson, J.W.4    Mendelson, C.R.5
  • 204
    • 30044447929 scopus 로고    scopus 로고
    • Unique suppression of prostaglandin H synthase-2 expression by inhibition of histone deacetylation, specifically in human amnion but not adjacent choriodecidua
    • Mitchell MD. Unique suppression of prostaglandin H synthase-2 expression by inhibition of histone deacetylation, specifically in human amnion but not adjacent choriodecidua. Mol Biol Cell 2006;17:549-53.
    • (2006) Mol Biol Cell , vol.17 , pp. 549-553
    • Mitchell, M.D.1


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