메뉴 건너뛰기




Volumn 10, Issue 6, 2010, Pages 613-619

Glucocorticoid receptor cofactors as therapeutic targets

Author keywords

[No Author keywords available]

Indexed keywords

ANTIANDROGEN; BETA CATENIN; BICOID; BRCA1 PROTEIN; GENE PRODUCT; GLUCOCORTICOID RECEPTOR; HOX PROTEIN; INTERLEUKIN 1BETA; MIFEPRISTONE; PROSTATE SPECIFIC ANTIGEN; PROTEIN B2M; PROTEIN NKX3 1; PROTEIN PP1 ALPHA; PROTEIN SKA2; SMALL INTERFERING RNA; THYROID RECEPTOR BETA 2; UNCLASSIFIED DRUG;

EID: 78149495249     PISSN: 14714892     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coph.2010.08.001     Document Type: Review
Times cited : (31)

References (60)
  • 1
    • 0021365332 scopus 로고
    • Glucocorticoid-receptor complexes in rat thymus cells. Rapid kinetic behavior and a cyclic model
    • Munck A., Holbrook N.J. Glucocorticoid-receptor complexes in rat thymus cells. Rapid kinetic behavior and a cyclic model. J Biol Chem 1984, 259:820-831.
    • (1984) J Biol Chem , vol.259 , pp. 820-831
    • Munck, A.1    Holbrook, N.J.2
  • 2
    • 33646153793 scopus 로고    scopus 로고
    • How much is enough? Modulation of dose-response curve for steroid receptor-regulated gene expression by changing concentrations of transcription factor
    • Simons S.S. How much is enough? Modulation of dose-response curve for steroid receptor-regulated gene expression by changing concentrations of transcription factor. Curr Top Med Chem 2006, 6:271-285.
    • (2006) Curr Top Med Chem , vol.6 , pp. 271-285
    • Simons, S.S.1
  • 3
    • 48949093044 scopus 로고    scopus 로고
    • What goes on behind closed doors: physiological versus pharmacological steroid hormone actions
    • Simons S.S. What goes on behind closed doors: physiological versus pharmacological steroid hormone actions. Bioessays 2008, 30:744-756.
    • (2008) Bioessays , vol.30 , pp. 744-756
    • Simons, S.S.1
  • 4
    • 0029643780 scopus 로고
    • Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid
    • Renaud J.-P., Rochel N., Ruff M., Vivat V., Chambon P., Gronemeyer H., Moras D. Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid. Nature 1995, 378:681-689.
    • (1995) Nature , vol.378 , pp. 681-689
    • Renaud, J.-P.1    Rochel, N.2    Ruff, M.3    Vivat, V.4    Chambon, P.5    Gronemeyer, H.6    Moras, D.7
  • 5
    • 21744435965 scopus 로고    scopus 로고
    • Controlling nuclear receptors: the circular logic of cofactor cycles
    • Perissi V., Rosenfeld M.G. Controlling nuclear receptors: the circular logic of cofactor cycles. Nat Rev Mol Cell Biol 2005, 6:542-554.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 542-554
    • Perissi, V.1    Rosenfeld, M.G.2
  • 7
    • 54549083372 scopus 로고    scopus 로고
    • Blocking estrogen signaling after the hormone: pyrimidine-core inhibitors of estrogen receptor-coactivator binding
    • Parent A.A., Gunther J.R., Katzenellenbogen J.A. Blocking estrogen signaling after the hormone: pyrimidine-core inhibitors of estrogen receptor-coactivator binding. J Med Chem 2008, 51:6512-6530.
    • (2008) J Med Chem , vol.51 , pp. 6512-6530
    • Parent, A.A.1    Gunther, J.R.2    Katzenellenbogen, J.A.3
  • 8
    • 67649909039 scopus 로고    scopus 로고
    • Improvement of pharmacological properties of irreversible thyroid receptor coactivator binding inhibitors
    • Hwang J.Y., Arnold L.A., Zhu F., Kosinski A., Mangano T.J., Setola V., Roth B.L., Guy R.K. Improvement of pharmacological properties of irreversible thyroid receptor coactivator binding inhibitors. J Med Chem 2009, 52:3892-3901.
    • (2009) J Med Chem , vol.52 , pp. 3892-3901
    • Hwang, J.Y.1    Arnold, L.A.2    Zhu, F.3    Kosinski, A.4    Mangano, T.J.5    Setola, V.6    Roth, B.L.7    Guy, R.K.8
  • 9
    • 34547731515 scopus 로고    scopus 로고
    • Nuclear receptor coregulators and human disease
    • Lonard D.M., Lanz R.B., O'Malley B.W. Nuclear receptor coregulators and human disease. Endocr Rev 2007, 28:575-587.
    • (2007) Endocr Rev , vol.28 , pp. 575-587
    • Lonard, D.M.1    Lanz, R.B.2    O'Malley, B.W.3
  • 10
    • 3242784885 scopus 로고    scopus 로고
    • Mechanism of the nuclear receptor molecular switch
    • Nagy L., Schwabe J.W. Mechanism of the nuclear receptor molecular switch. Trends Biochem Sci 2004, 29:317-324.
    • (2004) Trends Biochem Sci , vol.29 , pp. 317-324
    • Nagy, L.1    Schwabe, J.W.2
  • 11
    • 33744792310 scopus 로고    scopus 로고
    • Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response
    • Rosenfeld M.G., Lunyak V.V., Glass C.K. Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. Genes Dev 2006, 20:1405-1428.
    • (2006) Genes Dev , vol.20 , pp. 1405-1428
    • Rosenfeld, M.G.1    Lunyak, V.V.2    Glass, C.K.3
  • 12
    • 33746030006 scopus 로고    scopus 로고
    • Effects of acetylation, polymerase phosphorylation, and DNA unwinding in glucocorticoid receptor transactivation
    • Kim Y., Sun Y., Chow C., Pommier Y.G., Simons S.S. Effects of acetylation, polymerase phosphorylation, and DNA unwinding in glucocorticoid receptor transactivation. J Steroid Biochem Mol Biol 2006, 100:3-17.
    • (2006) J Steroid Biochem Mol Biol , vol.100 , pp. 3-17
    • Kim, Y.1    Sun, Y.2    Chow, C.3    Pommier, Y.G.4    Simons, S.S.5
  • 13
    • 0033347396 scopus 로고    scopus 로고
    • Opposing effects of corepressor and coactivators in determining the dose-response curve of agonists, and residual agonist activity of antagonists, for glucocorticoid receptor regulated gene expression
    • Szapary D., Huang Y., Simons S.S. Opposing effects of corepressor and coactivators in determining the dose-response curve of agonists, and residual agonist activity of antagonists, for glucocorticoid receptor regulated gene expression. Mol Endocrinol 1999, 13:2108-2121.
    • (1999) Mol Endocrinol , vol.13 , pp. 2108-2121
    • Szapary, D.1    Huang, Y.2    Simons, S.S.3
  • 15
    • 13544275104 scopus 로고    scopus 로고
    • Glucocorticoid receptor ligand binding domain is sufficient for the modulation of glucocorticoid induction properties by homologous receptors, coactivator transcription intermediary factor 2, and Ubc9
    • Cho S., Kagan B.L., Blackford J.A., Szapary D., Simons S.S. Glucocorticoid receptor ligand binding domain is sufficient for the modulation of glucocorticoid induction properties by homologous receptors, coactivator transcription intermediary factor 2, and Ubc9. Mol Endocrinol 2005, 19:290-311.
    • (2005) Mol Endocrinol , vol.19 , pp. 290-311
    • Cho, S.1    Kagan, B.L.2    Blackford, J.A.3    Szapary, D.4    Simons, S.S.5
  • 16
    • 34548252291 scopus 로고    scopus 로고
    • Nuclear receptor coregulators: judges, juries, and executioners of cellular regulation
    • Lonard D.M., O'Malley B.W. Nuclear receptor coregulators: judges, juries, and executioners of cellular regulation. Mol Cell 2007, 27:691-700.
    • (2007) Mol Cell , vol.27 , pp. 691-700
    • Lonard, D.M.1    O'Malley, B.W.2
  • 17
    • 34447099234 scopus 로고    scopus 로고
    • Probing the limits to positional information
    • Gregor T., Tank D.W., Wieschaus E.F., Bialek W. Probing the limits to positional information. Cell 2007, 130:153-164.
    • (2007) Cell , vol.130 , pp. 153-164
    • Gregor, T.1    Tank, D.W.2    Wieschaus, E.F.3    Bialek, W.4
  • 18
    • 34547220308 scopus 로고    scopus 로고
    • Developmental biology: a ten per cent solution
    • Reinitz J. Developmental biology: a ten per cent solution. Nature 2007, 448:420-421.
    • (2007) Nature , vol.448 , pp. 420-421
    • Reinitz, J.1
  • 19
    • 0034460335 scopus 로고    scopus 로고
    • Mice with an increased glucocorticoid receptor gene dosage show enhanced resistance to stress and endotoxic shock
    • Reichardt H.M., Umland T., Bauer A., Kretz O., Schutz G. Mice with an increased glucocorticoid receptor gene dosage show enhanced resistance to stress and endotoxic shock. Mol Cell Biol 2000, 20:9009-9017.
    • (2000) Mol Cell Biol , vol.20 , pp. 9009-9017
    • Reichardt, H.M.1    Umland, T.2    Bauer, A.3    Kretz, O.4    Schutz, G.5
  • 20
    • 70349305108 scopus 로고    scopus 로고
    • Modulation of glucocorticoid receptor induction properties by cofactors in peripheral blood mononuclear cells
    • Luo M., Simons S.S. Modulation of glucocorticoid receptor induction properties by cofactors in peripheral blood mononuclear cells. Hum Immunol 2009, 70:785-789.
    • (2009) Hum Immunol , vol.70 , pp. 785-789
    • Luo, M.1    Simons, S.S.2
  • 22
    • 1842530978 scopus 로고    scopus 로고
    • Differential requirement for steroidogenic factor-1 gene dosage in adrenal development versus endocrine function
    • Bland M.L., Fowkes R.C., Ingraham H.A. Differential requirement for steroidogenic factor-1 gene dosage in adrenal development versus endocrine function. Mol Endocrinol 2004, 18:941-952.
    • (2004) Mol Endocrinol , vol.18 , pp. 941-952
    • Bland, M.L.1    Fowkes, R.C.2    Ingraham, H.A.3
  • 23
    • 0035816687 scopus 로고    scopus 로고
    • Transactivation specificity of glucocorticoid vs. progesterone receptors: role of functionally different interactions of transcription factors with amino- and carboxyl-terminal receptor domains
    • Song L.-N., Huse B., Rusconi S., Simons S.S. Transactivation specificity of glucocorticoid vs. progesterone receptors: role of functionally different interactions of transcription factors with amino- and carboxyl-terminal receptor domains. J Biol Chem 2001, 276:24806-24816.
    • (2001) J Biol Chem , vol.276 , pp. 24806-24816
    • Song, L.-N.1    Huse, B.2    Rusconi, S.3    Simons, S.S.4
  • 24
    • 39149118308 scopus 로고    scopus 로고
    • Differential modulation of glucocorticoid and progesterone receptor transactivation
    • Szapary D., Song L.-N., He Y., Simons S.S. Differential modulation of glucocorticoid and progesterone receptor transactivation. Mol Cell Endocrinol 2008, 283:114-126.
    • (2008) Mol Cell Endocrinol , vol.283 , pp. 114-126
    • Szapary, D.1    Song, L.-N.2    He, Y.3    Simons, S.S.4
  • 25
    • 77950682598 scopus 로고    scopus 로고
    • STAMP alters the growth of transformed and ovarian cancer cells
    • He Y., Blackford J.A., Kohn E.C., Simons S.S. STAMP alters the growth of transformed and ovarian cancer cells. BMC Cancer 2010, 10:128.
    • (2010) BMC Cancer , vol.10 , pp. 128
    • He, Y.1    Blackford, J.A.2    Kohn, E.C.3    Simons, S.S.4
  • 26
    • 2542486258 scopus 로고    scopus 로고
    • Equilibrium interactions of corepressors and coactivators modulate the properties of agonist and antagonist complexes of glucocorticoid receptors
    • Wang Q., Blackford J.A., Song L.-N., Huang Y., Simons S.S. Equilibrium interactions of corepressors and coactivators modulate the properties of agonist and antagonist complexes of glucocorticoid receptors. Mol Endocrinol 2004, 18:1376-1395.
    • (2004) Mol Endocrinol , vol.18 , pp. 1376-1395
    • Wang, Q.1    Blackford, J.A.2    Song, L.-N.3    Huang, Y.4    Simons, S.S.5
  • 27
    • 58949097528 scopus 로고    scopus 로고
    • Ligand-selective transactivation and transrepression via the glucocorticoid receptor: role of cofactor interaction
    • Ronacher K., Hadley K., Avenant C., Stubsrud E., Simons S.S., Louw A., Hapgood J.P. Ligand-selective transactivation and transrepression via the glucocorticoid receptor: role of cofactor interaction. Mol Cell Endocrinol 2009, 299:219-231.
    • (2009) Mol Cell Endocrinol , vol.299 , pp. 219-231
    • Ronacher, K.1    Hadley, K.2    Avenant, C.3    Stubsrud, E.4    Simons, S.S.5    Louw, A.6    Hapgood, J.P.7
  • 28
    • 33748121414 scopus 로고    scopus 로고
    • Nuclear compartmentalization of N-CoR and its interactions with steroid receptors
    • Wu Y., Kawate H., Ohnaka K., Nawata H., Takayanagi R. Nuclear compartmentalization of N-CoR and its interactions with steroid receptors. Mol Cell Biol 2006, 26:6633-6655.
    • (2006) Mol Cell Biol , vol.26 , pp. 6633-6655
    • Wu, Y.1    Kawate, H.2    Ohnaka, K.3    Nawata, H.4    Takayanagi, R.5
  • 29
    • 33746507785 scopus 로고    scopus 로고
    • The corepressors silencing mediator of retinoid and thyroid hormone receptor and nuclear receptor corepressor are involved in agonist- and antagonist-regulated transcription by androgen receptor
    • Yoon H.G., Wong J. The corepressors silencing mediator of retinoid and thyroid hormone receptor and nuclear receptor corepressor are involved in agonist- and antagonist-regulated transcription by androgen receptor. Mol Endocrinol 2006, 20:1048-1060.
    • (2006) Mol Endocrinol , vol.20 , pp. 1048-1060
    • Yoon, H.G.1    Wong, J.2
  • 30
    • 73649133638 scopus 로고    scopus 로고
    • G protein pathway suppressor 2 (GPS2) is a transcriptional corepressor important for estrogen receptor alpha-mediated transcriptional regulation
    • Cheng X., Kao H.Y. G protein pathway suppressor 2 (GPS2) is a transcriptional corepressor important for estrogen receptor alpha-mediated transcriptional regulation. J Biol Chem 2009, 284:36395-36404.
    • (2009) J Biol Chem , vol.284 , pp. 36395-36404
    • Cheng, X.1    Kao, H.Y.2
  • 31
    • 34447305765 scopus 로고    scopus 로고
    • Amino-terminal domain of TIF2 is involved in competing for corepressor binding to glucocorticoid and progesterone receptors
    • Wang D., Wang Q., Awasthi S., Simons S.S. Amino-terminal domain of TIF2 is involved in competing for corepressor binding to glucocorticoid and progesterone receptors. Biochemistry 2007, 48:8036-8049.
    • (2007) Biochemistry , vol.48 , pp. 8036-8049
    • Wang, D.1    Wang, Q.2    Awasthi, S.3    Simons, S.S.4
  • 33
    • 27844519279 scopus 로고    scopus 로고
    • Interaction of beta-catenin and TIF2/GRIP1 in transcriptional activation by the androgen receptor
    • Song L.N., Gelmann E.P. Interaction of beta-catenin and TIF2/GRIP1 in transcriptional activation by the androgen receptor. J Biol Chem 2005, 280:37853-37867.
    • (2005) J Biol Chem , vol.280 , pp. 37853-37867
    • Song, L.N.1    Gelmann, E.P.2
  • 34
    • 73249149751 scopus 로고    scopus 로고
    • HDAC6 regulates androgen receptor hypersensitivity and nuclear localization via modulating Hsp90 acetylation in castration-resistant prostate cancer
    • Ai J., Wang Y., Dar J.A., Liu J., Liu L., Nelson J.B., Wang Z. HDAC6 regulates androgen receptor hypersensitivity and nuclear localization via modulating Hsp90 acetylation in castration-resistant prostate cancer. Mol Endocrinol 2009, 23:1963-1972.
    • (2009) Mol Endocrinol , vol.23 , pp. 1963-1972
    • Ai, J.1    Wang, Y.2    Dar, J.A.3    Liu, J.4    Liu, L.5    Nelson, J.B.6    Wang, Z.7
  • 35
    • 54849420674 scopus 로고    scopus 로고
    • The F-domain of estrogen receptor-alpha inhibits ligand induced receptor dimerization
    • Yang J., Singleton D.W., Shaughnessy E.A., Khan S.A. The F-domain of estrogen receptor-alpha inhibits ligand induced receptor dimerization. Mol Cell Endocrinol 2008, 295:94-100.
    • (2008) Mol Cell Endocrinol , vol.295 , pp. 94-100
    • Yang, J.1    Singleton, D.W.2    Shaughnessy, E.A.3    Khan, S.A.4
  • 38
    • 70350450946 scopus 로고    scopus 로고
    • FoxA1 binding directs chromatin structure and the functional response of a glucocorticoid receptor-regulated promoter
    • Belikov S., Astrand C., Wrange O. FoxA1 binding directs chromatin structure and the functional response of a glucocorticoid receptor-regulated promoter. Mol Cell Biol 2009, 29:5413-5425.
    • (2009) Mol Cell Biol , vol.29 , pp. 5413-5425
    • Belikov, S.1    Astrand, C.2    Wrange, O.3
  • 39
    • 31344446119 scopus 로고    scopus 로고
    • Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression
    • Ito K., Yamamura S., Essilfie-Quaye S., Cosio B., Ito M., Barnes P.J., Adcock I.M. Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression. J Exp Med 2006, 203:7-13.
    • (2006) J Exp Med , vol.203 , pp. 7-13
    • Ito, K.1    Yamamura, S.2    Essilfie-Quaye, S.3    Cosio, B.4    Ito, M.5    Barnes, P.J.6    Adcock, I.M.7
  • 40
    • 66149124844 scopus 로고    scopus 로고
    • Mechanisms underlying the control of progesterone receptor transcriptional activity by SUMOylation
    • Abdel-Hafiz H., Dudevoir M.L., Horwitz K.B. Mechanisms underlying the control of progesterone receptor transcriptional activity by SUMOylation. J Biol Chem 2009, 284:9099-9108.
    • (2009) J Biol Chem , vol.284 , pp. 9099-9108
    • Abdel-Hafiz, H.1    Dudevoir, M.L.2    Horwitz, K.B.3
  • 41
    • 33847058518 scopus 로고    scopus 로고
    • Linkage of progestin and epidermal growth factor signaling: phosphorylation of progesterone receptors mediates transcriptional hypersensitivity and increased ligand-independent breast cancer cell growth
    • Daniel A.R., Qiu M., Faivre E.J., Ostrander J.H., Skildum A., Lange C.A. Linkage of progestin and epidermal growth factor signaling: phosphorylation of progesterone receptors mediates transcriptional hypersensitivity and increased ligand-independent breast cancer cell growth. Steroids 2007, 72:188-201.
    • (2007) Steroids , vol.72 , pp. 188-201
    • Daniel, A.R.1    Qiu, M.2    Faivre, E.J.3    Ostrander, J.H.4    Skildum, A.5    Lange, C.A.6
  • 42
    • 38049013817 scopus 로고    scopus 로고
    • CR6-interacting factor 1 represses the transactivation of androgen receptor by direct interaction
    • Suh J.H., Shong M., Choi H.S., Lee K. CR6-interacting factor 1 represses the transactivation of androgen receptor by direct interaction. Mol Endocrinol 2008, 22:33-46.
    • (2008) Mol Endocrinol , vol.22 , pp. 33-46
    • Suh, J.H.1    Shong, M.2    Choi, H.S.3    Lee, K.4
  • 43
    • 58849127943 scopus 로고    scopus 로고
    • FoxO1 mediates PTEN suppression of androgen receptor N- and C-terminal interactions and coactivator recruitment
    • Ma Q., Fu W., Li P., Nicosia S.V., Jenster G., Zhang X., Bai W. FoxO1 mediates PTEN suppression of androgen receptor N- and C-terminal interactions and coactivator recruitment. Mol Endocrinol 2009, 23:213-225.
    • (2009) Mol Endocrinol , vol.23 , pp. 213-225
    • Ma, Q.1    Fu, W.2    Li, P.3    Nicosia, S.V.4    Jenster, G.5    Zhang, X.6    Bai, W.7
  • 44
    • 67651176090 scopus 로고    scopus 로고
    • Molecular characterization of SMILE as a novel corepressor of nuclear receptors
    • Xie Y.B., Nedumaran B., Choi H.S. Molecular characterization of SMILE as a novel corepressor of nuclear receptors. Nucleic Acids Res 2009, 37:4100-4115.
    • (2009) Nucleic Acids Res , vol.37 , pp. 4100-4115
    • Xie, Y.B.1    Nedumaran, B.2    Choi, H.S.3
  • 45
    • 0034081880 scopus 로고    scopus 로고
    • Response element and coactivator-mediated conformational change of the vitamin D(3) receptor permits sensitive interaction with agonists
    • Herdick M., Bury Y., Quack M., Uskokovic M.R., Polly P., Carlberg C. Response element and coactivator-mediated conformational change of the vitamin D(3) receptor permits sensitive interaction with agonists. Mol Pharmacol 2000, 57:1206-1217.
    • (2000) Mol Pharmacol , vol.57 , pp. 1206-1217
    • Herdick, M.1    Bury, Y.2    Quack, M.3    Uskokovic, M.R.4    Polly, P.5    Carlberg, C.6
  • 46
    • 22344443370 scopus 로고    scopus 로고
    • Pituitary resistance to thyroid hormone syndrome is associated with T3 receptor mutants that selectively impair beta2 isoform function
    • Wan W., Farboud B., Privalsky M.L. Pituitary resistance to thyroid hormone syndrome is associated with T3 receptor mutants that selectively impair beta2 isoform function. Mol Endocrinol 2005, 19:1529-1542.
    • (2005) Mol Endocrinol , vol.19 , pp. 1529-1542
    • Wan, W.1    Farboud, B.2    Privalsky, M.L.3
  • 47
    • 2442478144 scopus 로고    scopus 로고
    • PML-RARA-RXR oligomers mediate retinoid and rexinoid/cAMP cross-talk in acute promyelocytic leukemia cell differentiation
    • Kamashev D., Vitoux D., De The H. PML-RARA-RXR oligomers mediate retinoid and rexinoid/cAMP cross-talk in acute promyelocytic leukemia cell differentiation. J Exp Med 2004, 199:1163-1174.
    • (2004) J Exp Med , vol.199 , pp. 1163-1174
    • Kamashev, D.1    Vitoux, D.2    De The, H.3
  • 48
    • 70350036005 scopus 로고    scopus 로고
    • Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1
    • Chen S., Kesler C.T., Paschal B.M., Balk S.P. Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1. J Biol Chem 2009, 284:25576-25584.
    • (2009) J Biol Chem , vol.284 , pp. 25576-25584
    • Chen, S.1    Kesler, C.T.2    Paschal, B.M.3    Balk, S.P.4
  • 52
    • 76749108107 scopus 로고    scopus 로고
    • FKBP51 promotes assembly of the Hsp90 chaperone complex and regulates androgen receptor signaling in prostate cancer cells
    • Ni L., Yang C.S., Gioeli D., Frierson H., Toft D.O., Paschal B.M. FKBP51 promotes assembly of the Hsp90 chaperone complex and regulates androgen receptor signaling in prostate cancer cells. Mol Cell Biol 2010, 30:1243-1253.
    • (2010) Mol Cell Biol , vol.30 , pp. 1243-1253
    • Ni, L.1    Yang, C.S.2    Gioeli, D.3    Frierson, H.4    Toft, D.O.5    Paschal, B.M.6
  • 53
    • 33745070996 scopus 로고    scopus 로고
    • Flanking sequence composition differentially affects the binding and functional characteristics of glucocorticoid receptor homo- and heterodimers
    • Morin B., Nichols L.A., Holland L.J. Flanking sequence composition differentially affects the binding and functional characteristics of glucocorticoid receptor homo- and heterodimers. Biochemistry 2006, 45:7299-7306.
    • (2006) Biochemistry , vol.45 , pp. 7299-7306
    • Morin, B.1    Nichols, L.A.2    Holland, L.J.3
  • 54
    • 65249167505 scopus 로고    scopus 로고
    • DNA binding site sequence directs glucocorticoid receptor structure and activity
    • Meijsing S.H., Pufall M.A., So A.Y., Bates D.L., Chen L., Yamamoto K.R. DNA binding site sequence directs glucocorticoid receptor structure and activity. Science 2009, 324:407-410.
    • (2009) Science , vol.324 , pp. 407-410
    • Meijsing, S.H.1    Pufall, M.A.2    So, A.Y.3    Bates, D.L.4    Chen, L.5    Yamamoto, K.R.6
  • 55
    • 77449099481 scopus 로고    scopus 로고
    • Glucocorticoid regulation of mouse and human dual specificity phosphatase 1 (DUSP1) genes: unusual cis-acting elements and unexpected evolutionary divergence
    • Tchen C.R., Martins J.R., Paktiawal N., Perelli R., Saklatvala J., Clark A.R. Glucocorticoid regulation of mouse and human dual specificity phosphatase 1 (DUSP1) genes: unusual cis-acting elements and unexpected evolutionary divergence. J Biol Chem 2010, 285:2642-2652.
    • (2010) J Biol Chem , vol.285 , pp. 2642-2652
    • Tchen, C.R.1    Martins, J.R.2    Paktiawal, N.3    Perelli, R.4    Saklatvala, J.5    Clark, A.R.6
  • 56
    • 0030477196 scopus 로고    scopus 로고
    • Steroid receptor transcriptional synergy is potentiated by disruption of the DNA-binding domain dimer interface
    • Liu W., Wang J., Yu G., Pearce D. Steroid receptor transcriptional synergy is potentiated by disruption of the DNA-binding domain dimer interface. Mol Endocrinol 1996, 10:1399-1406.
    • (1996) Mol Endocrinol , vol.10 , pp. 1399-1406
    • Liu, W.1    Wang, J.2    Yu, G.3    Pearce, D.4
  • 57
    • 33847792712 scopus 로고    scopus 로고
    • Thermodynamic analysis of progesterone receptor-promoter interactions reveals a molecular model for isoform-specific function
    • Connaghan-Jones K.D., Heneghan A.F., Miura M.T., Bain D.L. Thermodynamic analysis of progesterone receptor-promoter interactions reveals a molecular model for isoform-specific function. Proc Natl Acad Sci U S A 2007, 104:2187-2192.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 2187-2192
    • Connaghan-Jones, K.D.1    Heneghan, A.F.2    Miura, M.T.3    Bain, D.L.4
  • 59
    • 33846912187 scopus 로고    scopus 로고
    • STAMP: a novel predicted factor assisting TIF2 actions in glucocorticoid receptor-mediated induction and repression
    • He Y., Simons S.S. STAMP: a novel predicted factor assisting TIF2 actions in glucocorticoid receptor-mediated induction and repression. Mol Cell Biol 2007, 27:1467-1485.
    • (2007) Mol Cell Biol , vol.27 , pp. 1467-1485
    • He, Y.1    Simons, S.S.2
  • 60
    • 47649127453 scopus 로고    scopus 로고
    • Mutations of glucocorticoid receptor differentially affect AF2 domain activity in a steroid-selective manner to alter the potency and efficacy of gene induction and repression
    • Tao Y.-G., Xu Y., Xu H.E., Simons S.S. Mutations of glucocorticoid receptor differentially affect AF2 domain activity in a steroid-selective manner to alter the potency and efficacy of gene induction and repression. Biochemistry 2008, 47:7648-7662.
    • (2008) Biochemistry , vol.47 , pp. 7648-7662
    • Tao, Y.-G.1    Xu, Y.2    Xu, H.E.3    Simons, S.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.