-
1
-
-
52149123619
-
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
-
10.1126/science.1164368, 2848990, 18772397
-
Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Kamiyama H, Jimeno A, Hong SM, Fu B, Lin MT, Calhoun ES, Kamiyama M, Walter K, Nikolskaya T, Nikolsky Y, Hartigan J, Smith DR, Hidalgo M, Leach SD, Klein AP, Jaffee EM, Goggins M, Maitra A, Iacobuzio-Donahue C, Eshleman JR, Kern SE, Hruban RH, Karchin R, Papadopoulos N, Parmigiani G, Vogelstein B, Velculescu VE, Kinzler KW. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 2008, 321:1801-1806. 10.1126/science.1164368, 2848990, 18772397.
-
(2008)
Science
, vol.321
, pp. 1801-1806
-
-
Jones, S.1
Zhang, X.2
Parsons, D.W.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
Mankoo, P.7
Carter, H.8
Kamiyama, H.9
Jimeno, A.10
Hong, S.M.11
Fu, B.12
Lin, M.T.13
Calhoun, E.S.14
Kamiyama, M.15
Walter, K.16
Nikolskaya, T.17
Nikolsky, Y.18
Hartigan, J.19
Smith, D.R.20
Hidalgo, M.21
Leach, S.D.22
Klein, A.P.23
Jaffee, E.M.24
Goggins, M.25
Maitra, A.26
Iacobuzio-Donahue, C.27
Eshleman, J.R.28
Kern, S.E.29
Hruban, R.H.30
Karchin, R.31
Papadopoulos, N.32
Parmigiani, G.33
Vogelstein, B.34
Velculescu, V.E.35
Kinzler, K.W.36
more..
-
2
-
-
65249154823
-
Androgen Receptor Roles in Spermatogenesis and Fertility: Lessons from Testicular Cell-Specific Androgen Receptor Knockout Mice
-
2662628, 19176467
-
Wang RS, Yeh S, Tzeng CR, Chang C. Androgen Receptor Roles in Spermatogenesis and Fertility: Lessons from Testicular Cell-Specific Androgen Receptor Knockout Mice. Endocr Rev 2009, 2662628, 19176467.
-
(2009)
Endocr Rev
-
-
Wang, R.S.1
Yeh, S.2
Tzeng, C.R.3
Chang, C.4
-
3
-
-
15544376261
-
Lessons in estrogen biology from knockout and transgenic animals
-
10.1146/annurev.physiol.67.040403.115914, 15709960
-
Hewitt SC, Harrell JC, Korach KS. Lessons in estrogen biology from knockout and transgenic animals. Annu Rev Physiol 2005, 67:285-308. 10.1146/annurev.physiol.67.040403.115914, 15709960.
-
(2005)
Annu Rev Physiol
, vol.67
, pp. 285-308
-
-
Hewitt, S.C.1
Harrell, J.C.2
Korach, K.S.3
-
4
-
-
0346996801
-
Progesterone involvement in breast development and tumorigenesis--as revealed by progesterone receptor "knockout" and "knockin" mouse models
-
10.1016/S0039-128X(03)00133-8, 14667968
-
Ismail PM, Amato P, Soyal SM, DeMayo FJ, Conneely OM, O'Malley BW, Lydon JP. Progesterone involvement in breast development and tumorigenesis--as revealed by progesterone receptor "knockout" and "knockin" mouse models. Steroids 2003, 68:779-787. 10.1016/S0039-128X(03)00133-8, 14667968.
-
(2003)
Steroids
, vol.68
, pp. 779-787
-
-
Ismail, P.M.1
Amato, P.2
Soyal, S.M.3
DeMayo, F.J.4
Conneely, O.M.5
O'Malley, B.W.6
Lydon, J.P.7
-
5
-
-
0031026744
-
Clinical potential of new antiestrogens
-
Gradishar WJ, Jordan VC. Clinical potential of new antiestrogens. J Clin Oncol 1997, 15:840-852.
-
(1997)
J Clin Oncol
, vol.15
, pp. 840-852
-
-
Gradishar, W.J.1
Jordan, V.C.2
-
6
-
-
42949158294
-
Current status and prospects of androgen depletion therapy for prostate cancer
-
10.1016/j.beem.2008.01.010, 18471787
-
Akaza H. Current status and prospects of androgen depletion therapy for prostate cancer. Best Pract Res Clin Endocrinol Metab 2008, 22:293-302. 10.1016/j.beem.2008.01.010, 18471787.
-
(2008)
Best Pract Res Clin Endocrinol Metab
, vol.22
, pp. 293-302
-
-
Akaza, H.1
-
7
-
-
33749442165
-
Glucocorticoid action and the development of selective glucocorticoid receptor ligands
-
full_text, 17045197
-
Cole TJ. Glucocorticoid action and the development of selective glucocorticoid receptor ligands. Biotechnol Annu Rev 2006, 12:269-300. full_text, 17045197.
-
(2006)
Biotechnol Annu Rev
, vol.12
, pp. 269-300
-
-
Cole, T.J.1
-
8
-
-
18044386374
-
RALES, EPHESUS and redox
-
10.1016/j.jsbmb.2004.12.010, 15860254
-
Funder JW. RALES, EPHESUS and redox. J Steroid Biochem Mol Biol 2005, 93:121-125. 10.1016/j.jsbmb.2004.12.010, 15860254.
-
(2005)
J Steroid Biochem Mol Biol
, vol.93
, pp. 121-125
-
-
Funder, J.W.1
-
9
-
-
33644987045
-
Effects of aldosterone on the vasculature
-
10.1161/01.HYP.0000201443.63240.a7, 16432039
-
Schiffrin EL. Effects of aldosterone on the vasculature. Hypertension 2006, 47:312-318. 10.1161/01.HYP.0000201443.63240.a7, 16432039.
-
(2006)
Hypertension
, vol.47
, pp. 312-318
-
-
Schiffrin, E.L.1
-
10
-
-
0037154974
-
Combinatorial control of gene expression by nuclear receptors and coregulators
-
10.1016/S0092-8674(02)00641-4, 11909518
-
McKenna NJ, O'Malley BW. Combinatorial control of gene expression by nuclear receptors and coregulators. Cell 2002, 108:465-474. 10.1016/S0092-8674(02)00641-4, 11909518.
-
(2002)
Cell
, vol.108
, pp. 465-474
-
-
McKenna, N.J.1
O'Malley, B.W.2
-
11
-
-
3242784885
-
Mechanism of the nuclear receptor molecular switch
-
10.1016/j.tibs.2004.04.006, 15276186
-
Nagy L, Schwabe JW. Mechanism of the nuclear receptor molecular switch. Trends Biochem Sci 2004, 29:317-324. 10.1016/j.tibs.2004.04.006, 15276186.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 317-324
-
-
Nagy, L.1
Schwabe, J.W.2
-
12
-
-
33646153793
-
How much is enough? Modulation of dose-response curve for steroid receptor-regulated gene expression by changing concentrations of transcription factor
-
10.2174/156802606776173465, 16515481
-
Simons SS. How much is enough? Modulation of dose-response curve for steroid receptor-regulated gene expression by changing concentrations of transcription factor. Current Topics in Medicinal Chemistry 2006, 6:271-285. 10.2174/156802606776173465, 16515481.
-
(2006)
Current Topics in Medicinal Chemistry
, vol.6
, pp. 271-285
-
-
Simons, S.S.1
-
13
-
-
33744792310
-
Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response
-
10.1101/gad.1424806, 16751179
-
Rosenfeld MG, Lunyak VV, Glass CK. Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. Genes Dev 2006, 20:1405-1428. 10.1101/gad.1424806, 16751179.
-
(2006)
Genes Dev
, vol.20
, pp. 1405-1428
-
-
Rosenfeld, M.G.1
Lunyak, V.V.2
Glass, C.K.3
-
14
-
-
48949093044
-
What goes on behind closed doors: physiological versus pharmacological steroid hormone actions
-
10.1002/bies.20792, 2742386, 18623071
-
Simons SS. What goes on behind closed doors: physiological versus pharmacological steroid hormone actions. Bioessays 2008, 30:744-756. 10.1002/bies.20792, 2742386, 18623071.
-
(2008)
Bioessays
, vol.30
, pp. 744-756
-
-
Simons, S.S.1
-
15
-
-
33846912187
-
STAMP: a novel predicted factor assisting TIF2 actions in glucocorticoid receptor-mediated induction and repression
-
10.1128/MCB.01360-06, 1800712, 17116691
-
He Y, Simons SS. STAMP: a novel predicted factor assisting TIF2 actions in glucocorticoid receptor-mediated induction and repression. Mol Cell Biol 2007, 27:1467-1485. 10.1128/MCB.01360-06, 1800712, 17116691.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 1467-1485
-
-
He, Y.1
Simons, S.S.2
-
16
-
-
39149118308
-
Differential modulation of glucocorticoid and progesterone receptor transactivation
-
10.1016/j.mce.2007.11.031, 2275900, 18215457
-
Szapary D, Song L-N, He Y, Simons SS. Differential modulation of glucocorticoid and progesterone receptor transactivation. Mol Cell Endocrinol 2008, 283:114-126. 10.1016/j.mce.2007.11.031, 2275900, 18215457.
-
(2008)
Mol Cell Endocrinol
, vol.283
, pp. 114-126
-
-
Szapary, D.1
Song, L.-.N.2
He, Y.3
Simons, S.S.4
-
17
-
-
48949094973
-
Modulation of transcription parameters in glucocorticoid receptor-mediated repression
-
10.1016/j.mce.2008.05.008, 2662735, 18583028
-
Sun Y, Tao Y, Kagan BL, He Y, Simons SS. Modulation of transcription parameters in glucocorticoid receptor-mediated repression. Mol Cell Endocrinol 2008, 295:59-69. 10.1016/j.mce.2008.05.008, 2662735, 18583028.
-
(2008)
Mol Cell Endocrinol
, vol.295
, pp. 59-69
-
-
Sun, Y.1
Tao, Y.2
Kagan, B.L.3
He, Y.4
Simons, S.S.5
-
18
-
-
20544457358
-
Tubulin polyglutamylase enzymes are members of the TTL domain protein family
-
10.1126/science.1113010, 15890843
-
Janke C, Rogowski K, Wloga D, Regnard C, Kajava AV, Strub JM, Temurak N, van Dijk J, Boucher D, van Dorsselaer A, Suryavanshi S, Gaertig J, Edde B. Tubulin polyglutamylase enzymes are members of the TTL domain protein family. Science 2005, 308:1758-1762. 10.1126/science.1113010, 15890843.
-
(2005)
Science
, vol.308
, pp. 1758-1762
-
-
Janke, C.1
Rogowski, K.2
Wloga, D.3
Regnard, C.4
Kajava, A.V.5
Strub, J.M.6
Temurak, N.7
van Dijk, J.8
Boucher, D.9
van Dorsselaer, A.10
Suryavanshi, S.11
Gaertig, J.12
Edde, B.13
-
19
-
-
0035114558
-
Cancer statistics, 2001
-
10.3322/canjclin.51.1.15, 11577478
-
Greenlee RT, Hill-Harmon MB, Murray T, Thun M. Cancer statistics, 2001. CA Cancer J Clin 2001, 51:15-36. 10.3322/canjclin.51.1.15, 11577478.
-
(2001)
CA Cancer J Clin
, vol.51
, pp. 15-36
-
-
Greenlee, R.T.1
Hill-Harmon, M.B.2
Murray, T.3
Thun, M.4
-
20
-
-
33846457870
-
Cancer statistics, 2007
-
10.3322/canjclin.57.1.43, 17237035
-
Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ. Cancer statistics, 2007. CA Cancer J Clin 2007, 57:43-66. 10.3322/canjclin.57.1.43, 17237035.
-
(2007)
CA Cancer J Clin
, vol.57
, pp. 43-66
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Murray, T.4
Xu, J.5
Thun, M.J.6
-
21
-
-
0034757916
-
Differentiation and growth potential of human ovarian surface epithelial cells expressing temperature-sensitive SV40 T antigen
-
10.1290/1071-2690(2001)037<0515:DAGPOH>2.0.CO;2, 11669285
-
Leung EH, Leung PC, Auersperg N. Differentiation and growth potential of human ovarian surface epithelial cells expressing temperature-sensitive SV40 T antigen. In Vitro Cell Dev Biol Anim 2001, 37:515-521. 10.1290/1071-2690(2001)037<0515:DAGPOH>2.0.CO;2, 11669285.
-
(2001)
In Vitro Cell Dev Biol Anim
, vol.37
, pp. 515-521
-
-
Leung, E.H.1
Leung, P.C.2
Auersperg, N.3
-
22
-
-
0036157392
-
Cancer statistics, 2002
-
10.3322/canjclin.52.1.23, 11814064
-
Jemal A, Thomas A, Murray T, Thun M. Cancer statistics, 2002. CA Cancer J Clin 2002, 52:23-47. 10.3322/canjclin.52.1.23, 11814064.
-
(2002)
CA Cancer J Clin
, vol.52
, pp. 23-47
-
-
Jemal, A.1
Thomas, A.2
Murray, T.3
Thun, M.4
-
23
-
-
4344707226
-
Early events in ovarian oncogenesis
-
10.1186/1477-7827-1-68, 239895, 14577833
-
Cvetkovic D. Early events in ovarian oncogenesis. Reprod Biol Endocrinol 2003, 1:68. 10.1186/1477-7827-1-68, 239895, 14577833.
-
(2003)
Reprod Biol Endocrinol
, vol.1
, pp. 68
-
-
Cvetkovic, D.1
-
24
-
-
58149489177
-
Ovarian carcinoma subtypes are different diseases: implications for biomarker studies
-
10.1371/journal.pmed.0050232, 2592352,2592352, 19053170
-
Kobel M, Kalloger SE, Boyd N, McKinney S, Mehl E, Palmer C, Leung S, Bowen NJ, Ionescu DN, Rajput A, Prentice LM, Miller D, Santos J, Swenerton K, Gilks CB, Huntsman D. Ovarian carcinoma subtypes are different diseases: implications for biomarker studies. PLoS Med 2008, 5:e232. 10.1371/journal.pmed.0050232, 2592352,2592352, 19053170.
-
(2008)
PLoS Med
, vol.5
-
-
Kobel, M.1
Kalloger, S.E.2
Boyd, N.3
McKinney, S.4
Mehl, E.5
Palmer, C.6
Leung, S.7
Bowen, N.J.8
Ionescu, D.N.9
Rajput, A.10
Prentice, L.M.11
Miller, D.12
Santos, J.13
Swenerton, K.14
Gilks, C.B.15
Huntsman, D.16
-
25
-
-
74649086620
-
Target genes suitable for silencing approaches and protein product interference in ovarian epithelial cancer
-
Malek A, Schafer R, Tchernitsa O. Target genes suitable for silencing approaches and protein product interference in ovarian epithelial cancer. Cancer Treat Rev
-
Cancer Treat Rev
-
-
Malek, A.1
Schafer, R.2
Tchernitsa, O.3
-
26
-
-
34250006413
-
Genome-wide association study identifies novel breast cancer susceptibility loci
-
10.1038/nature05887, 2714974, 17529967
-
Easton DF, Pooley KA, Dunning AM, Pharoah PD, Thompson D, Ballinger DG, Struewing JP, Morrison J, Field H, Luben R, Wareham N, Ahmed S, Healey CS, Bowman R, Meyer KB, Haiman CA, Kolonel LK, Henderson BE, Le Marchand L, Brennan P, Sangrajrang S, Gaborieau V, Odefrey F, Shen CY, Wu PE, Wang HC, Eccles D, Evans DG, Peto J, Fletcher O, Johnson N, Seal S, Stratton MR, Rahman N, Chenevix-Trench G, Bojesen SE, Nordestgaard BG, Axelsson CK, Garcia-Closas M, Brinton L, Chanock S, Lissowska J, Peplonska B, Nevanlinna H, Fagerholm R, Eerola H, Kang D, Yoo KY, Noh DY, Ahn SH, Hunter DJ, Hankinson SE, Cox DG, Hall P, Wedren S, Liu J, Low YL, Bogdanova N, Schurmann P, Dork T, Tollenaar RA, Jacobi CE, Devilee P, Klijn JG, Sigurdson AJ, Doody MM, Alexander BH, Zhang J, Cox A, Brock IW, MacPherson G, Reed MW, Couch FJ, Goode EL, Olson JE, Meijers-Heijboer H, Ouweland A, Uitterlinden A, Rivadeneira F, Milne RL, Ribas G, Gonzalez-Neira A, Benitez J, Hopper JL, McCredie M, Southey M, Giles GG, Schroen C, Justenhoven C, Brauch H, Hamann U, Ko YD, Spurdle AB, Beesley J, Chen X, Mannermaa A, Kosma VM, Kataja V, Hartikainen J, Day NE, Cox DR, Ponder BA. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 2007, 447:1087-1093. 10.1038/nature05887, 2714974, 17529967.
-
(2007)
Nature
, vol.447
, pp. 1087-1093
-
-
Easton, D.F.1
Pooley, K.A.2
Dunning, A.M.3
Pharoah, P.D.4
Thompson, D.5
Ballinger, D.G.6
Struewing, J.P.7
Morrison, J.8
Field, H.9
Luben, R.10
Wareham, N.11
Ahmed, S.12
Healey, C.S.13
Bowman, R.14
Meyer, K.B.15
Haiman, C.A.16
Kolonel, L.K.17
Henderson, B.E.18
Le Marchand, L.19
Brennan, P.20
Sangrajrang, S.21
Gaborieau, V.22
Odefrey, F.23
Shen, C.Y.24
Wu, P.E.25
Wang, H.C.26
Eccles, D.27
Evans, D.G.28
Peto, J.29
Fletcher, O.30
Johnson, N.31
Seal, S.32
Stratton, M.R.33
Rahman, N.34
Chenevix-Trench, G.35
Bojesen, S.E.36
Nordestgaard, B.G.37
Axelsson, C.K.38
Garcia-Closas, M.39
Brinton, L.40
Chanock, S.41
Lissowska, J.42
Peplonska, B.43
Nevanlinna, H.44
Fagerholm, R.45
Eerola, H.46
Kang, D.47
Yoo, K.Y.48
Noh, D.Y.49
Ahn, S.H.50
Hunter, D.J.51
Hankinson, S.E.52
Cox, D.G.53
Hall, P.54
Wedren, S.55
Liu, J.56
Low, Y.L.57
Bogdanova, N.58
Schurmann, P.59
Dork, T.60
Tollenaar, R.A.61
Jacobi, C.E.62
Devilee, P.63
Klijn, J.G.64
Sigurdson, A.J.65
Doody, M.M.66
Alexander, B.H.67
Zhang, J.68
Cox, A.69
Brock, I.W.70
MacPherson, G.71
Reed, M.W.72
Couch, F.J.73
Goode, E.L.74
Olson, J.E.75
Meijers-Heijboer, H.76
Ouweland, A.77
Uitterlinden, A.78
Rivadeneira, F.79
Milne, R.L.80
Ribas, G.81
Gonzalez-Neira, A.82
Benitez, J.83
Hopper, J.L.84
McCredie, M.85
Southey, M.86
Giles, G.G.87
Schroen, C.88
Justenhoven, C.89
Brauch, H.90
Hamann, U.91
Ko, Y.D.92
Spurdle, A.B.93
Beesley, J.94
Chen, X.95
Mannermaa, A.96
Kosma, V.M.97
Kataja, V.98
Hartikainen, J.99
more..
-
27
-
-
0033347396
-
Opposing effects of corepressor and coactivators in determining the dose-response curve of agonists, and residual agonist activity of antagonists, for glucocorticoid receptor regulated gene expression
-
10.1210/me.13.12.2108, 10598585
-
Szapary D, Huang Y, Simons SS. Opposing effects of corepressor and coactivators in determining the dose-response curve of agonists, and residual agonist activity of antagonists, for glucocorticoid receptor regulated gene expression. Mol Endocrinol 1999, 13:2108-2121. 10.1210/me.13.12.2108, 10598585.
-
(1999)
Mol Endocrinol
, vol.13
, pp. 2108-2121
-
-
Szapary, D.1
Huang, Y.2
Simons, S.S.3
-
28
-
-
0034730644
-
Evidence for a common step in three different processes for modulating the kinetic properties of glucocorticoid receptor-induced gene transcription
-
10.1074/jbc.M005418200, 10899170
-
Chen S, Sarlis NJ, Simons SS. Evidence for a common step in three different processes for modulating the kinetic properties of glucocorticoid receptor-induced gene transcription. J Biol Chem 2000, 275:30106-30117. 10.1074/jbc.M005418200, 10899170.
-
(2000)
J Biol Chem
, vol.275
, pp. 30106-30117
-
-
Chen, S.1
Sarlis, N.J.2
Simons, S.S.3
-
29
-
-
26444590484
-
Involvement of {beta}-catenin and unusual behavior of CBP and p300 in glucocorticosteroid signaling in Schwann cells
-
10.1073/pnas.0506930102, 1242324, 16186500
-
Fonte C, Grenier J, Trousson A, Chauchereau A, Lahuna O, Baulieu EE, Schumacher M, Massaad C. Involvement of {beta}-catenin and unusual behavior of CBP and p300 in glucocorticosteroid signaling in Schwann cells. Proc Natl Acad Sci USA 2005, 102:14260-14265. 10.1073/pnas.0506930102, 1242324, 16186500.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 14260-14265
-
-
Fonte, C.1
Grenier, J.2
Trousson, A.3
Chauchereau, A.4
Lahuna, O.5
Baulieu, E.E.6
Schumacher, M.7
Massaad, C.8
-
30
-
-
20744456118
-
Histone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein
-
10.1128/MCB.25.13.5552-5566.2005, 1156991, 15964811
-
Guidez F, Howell L, Isalan M, Cebrat M, Alani RM, Ivins S, Hormaeche I, McConnell MJ, Pierce S, Cole PA, Licht J, Zelent A. Histone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein. Mol Cell Biol 2005, 25:5552-5566. 10.1128/MCB.25.13.5552-5566.2005, 1156991, 15964811.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 5552-5566
-
-
Guidez, F.1
Howell, L.2
Isalan, M.3
Cebrat, M.4
Alani, R.M.5
Ivins, S.6
Hormaeche, I.7
McConnell, M.J.8
Pierce, S.9
Cole, P.A.10
Licht, J.11
Zelent, A.12
-
31
-
-
32244435093
-
Reconstitution of chromatin transcription with purified components reveals a chromatin-specific repressive activity of p300
-
10.1038/nsmb1048, 16415879
-
Santoso B, Kadonaga JT. Reconstitution of chromatin transcription with purified components reveals a chromatin-specific repressive activity of p300. Nat Struct Mol Biol 2006, 13:131-139. 10.1038/nsmb1048, 16415879.
-
(2006)
Nat Struct Mol Biol
, vol.13
, pp. 131-139
-
-
Santoso, B.1
Kadonaga, J.T.2
-
32
-
-
47649127453
-
Mutations of glucocorticoid receptor differentially affect AF2 domain activity in a steroid-selective manner to alter the potency and efficacy of gene induction and repression
-
10.1021/bi800472w, 2678802, 18578507
-
Tao Y-G, Xu Y, Xu HE, Simons SSJ. Mutations of glucocorticoid receptor differentially affect AF2 domain activity in a steroid-selective manner to alter the potency and efficacy of gene induction and repression. Biochemistry 2008, 47:7648-7662. 10.1021/bi800472w, 2678802, 18578507.
-
(2008)
Biochemistry
, vol.47
, pp. 7648-7662
-
-
Tao, Y.-.G.1
Xu, Y.2
Xu, H.E.3
Simons, S.S.J.4
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