Androgen Modulation of Coregulator Expression in Prostate Cancer Cells

Molecular Endocrinology

Volumn 23, Issue 4, 2009, Pages 572-583

  Heemers, Hannelore V ^a   Regan, Kevin M ^a   Schmidt, Lucy J ^a   Anderson, S Keith ^a   Ballman, Karla V ^a   Tindall, Donald J ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; PROTEIN P300; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FHL2; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION;

ANDROGENS; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; TRANSCRIPTION FACTORS;

EID: 64749107759     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2008-0363     Document Type: Article

References (43)

1. Grossmann ME, Huang H, Tindall DJ 2001 Androgen receptor signaling in androgen-refractory prostate cancer. J Natl Cancer Inst 93:1687-1697
2. Litvinov IV, De Marzo AM, Isaacs JT 2003 Is the Achilles' heel for prostate cancer therapy a gain of function in androgen receptor signaling? J Clin Endocrinol Metab 88:2972-2982
3. Debes JD, Tindall DJ 2004 Mechanisms of androgen-refractory prostate cancer. N Engl J Med 351:1488-1490
4. Balk SP, Knudsen KE 2008 AR, the cell cycle, and prostate cancer. Nucl Recept Signal 6:e001
5. MiyamotoH,Messing EM, ChangC 2004 Androgen deprivation therapy for prostate cancer: current status and future prospects. Prostate 61:332-353
6. Roy-BurmanP,Tindall DJ, Robins DM, Greenberg NM, Hendrix MJ, Mohla S, Getzenberg RH, Isaacs JT, Pienta KJ 2005 Androgens and prostate cancer: are the descriptors valid? Cancer Biol Ther 4:4-5
7. Mohler JL 2008 Castration-recurrent prostate cancer is not androgen-independent. Adv Exp Med Biol 617:223-234
8. Heinlein CA, Chang C 2002 Androgen receptor (AR) coregulators: an overview. Endocr Rev 23:175-200
9. Heemers HV, Tindall DJ 2007 Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex. Endocr Rev 28:778-808
10. Wang Q, Li W, Liu XS, Carroll JS, Jänne OA, Keeton EK, Chinnaiyan AM, Pienta KJ, Brown M 2007 A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth. Mol Cell 27: 380-392
11. Bolton EC, So AY, Chaivorapol C, Ha CM, Li H, Yamamoto KR 2007 Celland gene-specific regulation of primary target genes by the androgen receptor. Genes Dev 21:2005-2017
12. Massie CE, Adryan B, Barbosa-Morais NL, Lynch AG, Tran MG, Neal DE, Mills IG 2007 New androgen receptor genomic targets show an interaction with the ETS1 transcription factor. EMBO Rep 8:871-878
13. Heemers HV, Tindall DJ 2005 Androgen receptor coregulatory proteins as potential therapeutic targets in the treatment of prostate cancer. Curr Cancer Ther Rev 1:175-186
14. Chmelar R, Buchanan G, Need EF, Tilley W, Greenberg NM 2007 Androgen receptor coregulators and their involvement in the development and progression of prostate cancer. Int J Cancer 120:719-733
15. Agoulnik IU, Weigel NL 2008 Androgen receptor coactivators and prostate cancer. Adv Exp Med Biol 617:245-255
16. Heemers HV, Sebo TJ, Debes JD, Regan KM, Raclaw KA, Murphy LM, Hobisch A, Culig Z, Tindall DJ 2007 Androgen deprivation increases p300 expression in prostate cancer cells. Cancer Res 67:3422-3430
17. Heemers HV, Regan KM, Dehm SM, Tindall DJ 2007 Androgen induction of the androgen receptor coactivator four and a half LIM domain protein-2: evidence for a role for serum response factor in prostate cancer. Cancer Res 67:10592-10599
18. Fan JB, Yeakley JM, Bibikova M, Chudin E, Wickham E, Chen J, Doucet D, Rigault P, Zhang B, Shen R, McBride C, Li HR, Fu XD, Oliphant A, Barker DL, Chee MS 2004 A versatile assay for high-throughput gene expression profiling on universal array matrices. Genome Res 14:878-885
19. BibikovaM,TalantovD,Chudin E,Yeakley JM, ChenJ, Doucet D,Wickham E, Atkins D, Barker D, Chee M, Wang Y, Fan JB 2004 Quantitative gene expression profiling in formalin-fixed, paraffin-embedded tissues using universal bead arrays. Am J Pathol 165:1799-1807
20. Waghray A, Feroze F, Schober MS, Yao F, Wood C, Puravs E, Krause M, Hanash S, Chen YQ 2001 Identification of androgen-regulated genes in the prostate cancer cell line LNCaP by serial analysis of gene expression and proteomic analysis. Proteomics 1:1327-1338
21. DePrimo SE, Diehn M, Nelson JB, Reiter RE, Matese J, Fero M, Tibshirani R, Brown PO, Brooks JD 2002 Transcriptional programs activated by exposure of human prostate cancer cells to androgen. Genome Biol 3:RE- SEARCH0032
22. Nelson PS, Clegg N, Arnold H, Ferguson C, Bonham M, White J, Hood L,Lin B 2002 The program of androgen-responsive genes in neoplastic prostate epithelium. Proc Natl Acad Sci USA 99:11890-11895
23. Clegg N, Eroglu B, Ferguson C, Arnold H, Moorman A, Nelson PS 2002 Digital expression profiles of the prostate androgen-response program. J Steroid Biochem Mol Biol 80:13-23
24. Segawa T, Nau ME, Xu LL, Chilukuri RN, Makarem M, Zhang W, Petrovics G, Sesterhenn IA, McLeod DG, Moul JW, Vahey M, Srivastava S 2002 Androgen-induced expression of endoplasmic reticulum (ER) stress response genes in prostate cancer cells. Oncogene 21:8749-8758
25. Dehm SM, Tindall DJ 2006 Molecular regulation of androgen action in prostate cancer. J Cell Biochem 99:333-344
26. Velasco AM, Gillis KA, Li Y, Brown EL, Sadler TM, Achilleos M, Greenberger LM, Frost P, Bai W, Zhang Y 2004 Identification and validation of novel androgen-regulated genes in prostate cancer. Endocrinology 145:3913- 3924
27. Cleutjens KB, van Eekelen CC, van der Korput HA, Brinkmann AO, Trapman J 1996 Two androgen response regions cooperate in steroid hormone regulated activity of the prostate-specific antigen promoter. J Biol Chem 271:6379-6388
28. Cleutjens KB, van der Korput HA, van Eekelen CC, van Rooij HC, Faber PW, Trapman J 1997 An androgen response element in a far upstream enhancer region is essential for high, androgen-regulated activity of the prostate-specific antigen promoter. Mol Endocrinol 11:148-161
29. Mitchell SH, Murtha PE, Zhang S, Zhu W, Young CY 2000 An androgen response element mediates LNCaP cell dependent androgen induction of the hK2 gene. Mol Cell Endocrinol 168:89-99
30. Heemers H, Verrijdt G, Organe S, Claessens F, Heyns W, Verhoeven G, Swinnen JV 2004 Identification of an androgen response element in intron 8 of the sterol regulatory element-binding protein cleavage-activating protein gene allowing direct regulation by the androgen receptor. J Biol Chem 279: 30880-30887
31. He ML, Jiang AL, Zhang PJ, Hu XY, Liu ZF, Yuan HQ, Zhang JY 2005 Identification of androgen-responsive element ARE and Sp1 element in the maspin promoter. Chin J Physiol 48:160-166
32. Agoulnik IU, Vaid A, Nakka M, Alvarado M, Bingman III WE, Erdem H, Frolov A, Smith CL, Ayala GE, Ittmann MM, Weigel NL 2006 Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer. Cancer Res 66:10594-10602
33. Chen PH, Tsao YP, Wang CC, Chen SL 2008 Nuclear receptor interaction protein, a coactivator of androgen receptors (AR), is regulated by ARand Sp1 to feed forward and activate its own gene expression through AR protein stability. Nucleic Acids Res 36:51-66
34. Murillo H, Huang H, Schmidt LJ, Smith DI, Tindall DJ 2001 Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state. Endocrinology 142:4795-4805
35. Comuzzi B, Nemes C, Schmidt S, Jasarevic Z, Lodde M, Pycha A, Bartsch G, Offner F, Culig Z, Hobisch A 2004 The androgen receptor co-activator CBP is up-regulated following androgen withdrawal and is highly expressed in advanced prostate cancer. J Pathol 204:159-166
36. Wu RC, Qin J, Yi P, Wong J, Tsai SY, Tsai MJ, O'Malley BW 2004 Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Mol Cell 15:937-949
37. Marshall TW, Link KA, Petre-Draviam CE, Knudsen KE 2003 Differential requirement of SWI/SNF for androgen receptor activity. J Biol Chem 278: 30605-30613
38. Gregory CW, He B, Johnson RT, Ford OH, Mohler JL, French FS, Wilson EM 2001 A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy. Cancer Res 61:4315- 4319
39. XueY, Canman JC, Lee CS, Nie Z,Yang D, Moreno GT, Young MK, Salmon ED, WangW 2000 The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes. Proc Natl Acad Sci USA 97:13015-13020
40. Ballman KV, Grill DE, Oberg AL, Therneau TM 2004 Faster cyclic loess: normalizing RNA arrays via linear models. Bioinformatics 20:2778 - 2786
41. Smyth GK 2004 Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 3:Article 3
42. Smyth GK 2005 Limma: linear models for microarray data. In: Gentleman R, Carey V, Dudoit S, Irizarry R, Huber W, eds. Bioinformatics and computational biology solutions using R and Bioconductor. New York: Springer; 397-420
43. Benjamini Y, Hochberg Y 1995 Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B 57:289-300