Targeting the polyamine transport system with benzazepine- and azepine-polyamine conjugates

Journal of Medicinal Chemistry

Volumn 53, Issue 21, 2010, Pages 7647-7663

  Tomasi, Sophie ^a   Renault, Jacques ^a   Martin, Bénédicte ^a   Duhieu, Stephane ^a   Cerec, Virginie ^a   Le Roch, Myriam ^a   Uriac, Philippe ^a   Delcros, Jean Guy ^a  

^a UNIVERSITÉ EUROPÉENNE DE BRETAGNE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

3,3' DIAMINODIPROPYLAMINE; AMIDINE; AZEPINE DERIVATIVE; BENZAZEPINE DERIVATIVE; ETHER DERIVATIVE; IMINOETHER DERIVATIVE; LACTAM; N 1 (4,5 DIHYDRO 3H 1 BENZAZEPIN 2 YL) 6,7 DIHYDROXYSPERMINE; N 1 (4,5 DIHYDRO 3H 1 BENZAZEPIN 2 YL) NORSPERMINE; N 1 (4,5 DIHYDRO 3H 1 BENZAZEPIN 2 YL) OCTANE 1,8 DIAMINE; N 1 (4,5 DIHYDRO 3H 1 BENZAZEPIN 2 YL) PUTRESCINE; N 1 (4,5 DIHYDRO 3H 1 BENZAZEPIN 2 YL) SPERMIDINE; N 1 (4,5 DIHYDRO 3H 1 BENZAZEPIN 2 YL) SPERMINE; N 1 (4,5 DIHYDRO 3H AZEPIN 2 YL) AZANONANE 1,9 DIAMINE; N 1 (4,5 DIHYDRO 3H AZEPIN 2 YL) NORSPERMIDINE; N 1 (4,5 DIHYDRO 3H AZEPIN 2 YL) OCTANE 1,8 DIAMINE; N 1 (4,5 DIHYDRO 3H AZEPIN 2 YL) SPERMIDINE; N 1 (4,5 DIHYDRO 3H AZEPIN 2 YL) SPERMINE; N 1 (7 AMINO 4,5 DIHYDRO 3H 1 BENZAZEPIN 2 YL) SPERMINE; N 1 (7 BROMO 4,5 DIHYDRO 3H 1 BENZAZEPIN 2 YL) SPERMINE; N 1 (7 METHOXY 4,5 DIHYDRO 3H 1 BENZAZEPIN 2 YL) SPERMINE; N 1 (7 NITRO 4,5 DIHYDRO 3H 1 BENZAZEPIN 2 YL) SPERMINE; N 8 (4,5 DIHYDRO 3H AZEPIN 2 YL) SPERMIDINE; N1 (4,5 DIHYDRO 3H 1 BENZAZEPIN 2 YL) HOMOSPERMINE; NITROBENZAZEPINE; PUTRESCINE; SPERMIDINE; SPERMINE; THIOLACTAM; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOSTASIS; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG SELECTIVITY; DRUG SYNTHESIS; DRUG TRANSPORT; NONHUMAN; NUCLEAR MEDICINE; POLYAMINE SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; AZEPINES; BENZAZEPINES; BIOLOGICAL TRANSPORT; CELL PROLIFERATION; CHO CELLS; CRICETINAE; CRICETULUS; DRUG SCREENING ASSAYS, ANTITUMOR; LEUKEMIA L1210; POLYAMINES; SPERMIDINE; SPERMINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78149242572     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm1007648     Document Type: Article

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