-
1
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander E.S., Linton L.M., Birren B., Nusbaum C., Zody M.C., Baldwin J., Devon K., Dewar K., Doyle M., FitzHugh W., Funke R., Gage D., Harris K., Heaford A., Howland J., Kann L., Lehoczky J., LeVine R., McEwan P., McKernan K., Meldrim J., Mesirov J.P., Miranda C., Morris W., Naylor J., Raymond C., Rosetti M., Santos R., Sheridan A., Sougnez C., Stange-Thomann N., Stojanovic N., Subramanian A., Wyman D., Rogers J., Sulston J., Ainscough R., Beck S., Bentley D., Burton J., Clee C., Carter N., Coulson A., Deadman R., Deloukas P., Dunham A., Dunham I., Durbin R., French L., Grafham D., Gregory S., Hubbard T., Humphray S., Hunt A., Jones M., Lloyd C., McMurray A., Matthews L., Mercer S., Milne S., Mullikin J.C., Mungall A., Plumb R., Ross M., Shownkeen R., Sims S., Waterston R.H., Wilson R.K., Hillier L.W., McPherson J.D., Marra M.A., Mardis E.R., Fulton L.A., Chinwalla A.T., Pepin K.H., Gish W.R., Chissoe S.L., Wendl M.C., Delehaunty K.D., Miner T.L., Delehaunty A., Kramer J.B., Cook L.L., Fulton R.S., Johnson D.L., Minx P.J., Clifton S.W., Hawkins T., Branscomb E., Predki P., Richardson P., Wenning S., Slezak T., Doggett N., Cheng J.F., Olsen A., Lucas S., Elkin C., Uberbacher E., Frazier M., Gibbs R.A., Muzny D.M., Scherer S.E., Bouck J.B., Sodergren E.J., Worley K.C., Rives C.M., Gorrell J.H., Metzker M.L., Naylor S.L., Kucherlapati R.S., Nelson D.L., Weinstock G.M., Sakaki Y., Fujiyama A., Hattori M., Yada T., Toyoda A., Itoh T., Kawagoe C., Watanabe H., Totoki Y., Taylor T., Weissenbach J., Heilig R., Saurin W., Artiguenave F., Brottier P., Bruls T., Pelletier E., Robert C., Wincker P., Smith D.R., Doucette-Stamm L., Rubenfield M., Weinstock K., Lee H.M., Dubois J., Rosenthal A., Platzer M., Nyakatura G., Taudien S., Rump A., Yang H., Yu J., Wang J., Huang G., Gu J., Hood L., Rowen L., Madan A., Qin S., Davis R.W., Federspiel N.A., Abola A.P., Proctor M.J., Myers R.M., Schmutz J., Dickson M., Grimwood J., Cox D.R., Olson M.V., Kaul R., Shimizu N., Kawasaki K., Minoshima S., Evans G.A., Athanasiou M., Schultz R., Roe B.A., Chen F., Pan H., Ramser J., Lehrach H., Reinhardt R., McCombie W.R., de la Bastide M., Dedhia N., Blocker H., Hornischer K., Nordsiek G., Agarwala R., Aravind L., Bailey J.A., Bateman A., Batzoglou S., Birney E., Bork P., Brown D.G., Burge C.B., Cerutti L., Chen H.C., Church D., Clamp M., Copley R.R., Doerks T., Eddy S.R., Eichler E.E., Furey T.S., Galagan J., Gilbert J.G., Harmon C., Hayashizaki Y., Haussler D., Hermjakob H., Hokamp K., Jang W., Johnson L.S., Jones T.A., Kasif S., Kaspryzk A., Kennedy S., Kent W.J., Kitts P., Koonin E.V., Korf I., Kulp D., Lancet D., Lowe T.M., McLysaght A., Mikkelsen T., Moran J.V., Mulder N., Pollara V.J., Ponting C.P., Schuler G., Schultz J., Slater G., Smit A.F., Stupka E., Szustakowski J., Thierry-Mieg D., Thierry-Mieg J., Wagner L., Wallis J., Wheeler R., Williams A., Wolf Y.I., Wolfe K.H., Yang S.P., Yeh R.F., Collins F., Guyer M.S., Peterson J., Felsenfeld A., Wetterstrand K.A., Patrinos A., Morgan M.J., de Jong P., Catanese J.J., Osoegawa K., Shizuya H., Choi S., Chen Y.J. Initial sequencing and analysis of the human genome. Nature 2001, 409:860-921.
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
Nusbaum, C.4
Zody, M.C.5
Baldwin, J.6
Devon, K.7
Dewar, K.8
Doyle, M.9
FitzHugh, W.10
Funke, R.11
Gage, D.12
Harris, K.13
Heaford, A.14
Howland, J.15
Kann, L.16
Lehoczky, J.17
LeVine, R.18
McEwan, P.19
McKernan, K.20
Meldrim, J.21
Mesirov, J.P.22
Miranda, C.23
Morris, W.24
Naylor, J.25
Raymond, C.26
Rosetti, M.27
Santos, R.28
Sheridan, A.29
Sougnez, C.30
Stange-Thomann, N.31
Stojanovic, N.32
Subramanian, A.33
Wyman, D.34
Rogers, J.35
Sulston, J.36
Ainscough, R.37
Beck, S.38
Bentley, D.39
Burton, J.40
Clee, C.41
Carter, N.42
Coulson, A.43
Deadman, R.44
Deloukas, P.45
Dunham, A.46
Dunham, I.47
Durbin, R.48
French, L.49
Grafham, D.50
Gregory, S.51
Hubbard, T.52
Humphray, S.53
Hunt, A.54
Jones, M.55
Lloyd, C.56
McMurray, A.57
Matthews, L.58
Mercer, S.59
Milne, S.60
Mullikin, J.C.61
Mungall, A.62
Plumb, R.63
Ross, M.64
Shownkeen, R.65
Sims, S.66
Waterston, R.H.67
Wilson, R.K.68
Hillier, L.W.69
McPherson, J.D.70
Marra, M.A.71
Mardis, E.R.72
Fulton, L.A.73
Chinwalla, A.T.74
Pepin, K.H.75
Gish, W.R.76
Chissoe, S.L.77
Wendl, M.C.78
Delehaunty, K.D.79
Miner, T.L.80
Delehaunty, A.81
Kramer, J.B.82
Cook, L.L.83
Fulton, R.S.84
Johnson, D.L.85
Minx, P.J.86
Clifton, S.W.87
Hawkins, T.88
Branscomb, E.89
Predki, P.90
Richardson, P.91
Wenning, S.92
Slezak, T.93
Doggett, N.94
Cheng, J.F.95
Olsen, A.96
Lucas, S.97
Elkin, C.98
Uberbacher, E.99
more..
-
2
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird A. DNA methylation patterns and epigenetic memory. Genes Dev. 2002, 16:6-21.
-
(2002)
Genes Dev.
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
3
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones P.A., Baylin S.B. The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 2002, 3:415-428.
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
4
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
Herman J.G., Baylin S.B. Gene silencing in cancer in association with promoter hypermethylation. N. Engl. J. Med. 2003, 349:2042-2054.
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
5
-
-
0022540321
-
CpG-rich islands and the function of DNA methylation
-
Bird A.P. CpG-rich islands and the function of DNA methylation. Nature 1986, 321:209-213.
-
(1986)
Nature
, vol.321
, pp. 209-213
-
-
Bird, A.P.1
-
6
-
-
0034625064
-
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a
-
Ramsahoye B.H., Biniszkiewicz D., Lyko F., Clark V., Bird A.P., Jaenisch R. Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:5237-5242.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 5237-5242
-
-
Ramsahoye, B.H.1
Biniszkiewicz, D.2
Lyko, F.3
Clark, V.4
Bird, A.P.5
Jaenisch, R.6
-
7
-
-
0025299347
-
The expected equilibrium of the CpG dinucleotide in vertebrate genomes under a mutation model
-
Sved J., Bird A. The expected equilibrium of the CpG dinucleotide in vertebrate genomes under a mutation model. Proc. Natl. Acad. Sci. U. S. A. 1990, 87:4692-4696.
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 4692-4696
-
-
Sved, J.1
Bird, A.2
-
8
-
-
0034780410
-
Reduced rates of gene loss, gene silencing, and gene mutation in Dnmt1-deficient embryonic stem cells
-
Chan M.F., van Amerongen R., Nijjar T., Cuppen E., Jones P.A., Laird P.W. Reduced rates of gene loss, gene silencing, and gene mutation in Dnmt1-deficient embryonic stem cells. Mol. Cell. Biol. 2001, 21:7587-7600.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 7587-7600
-
-
Chan, M.F.1
van Amerongen, R.2
Nijjar, T.3
Cuppen, E.4
Jones, P.A.5
Laird, P.W.6
-
10
-
-
0037133565
-
Comprehensive analysis of CpG islands in human chromosomes 21 and 22
-
Takai D., Jones P.A. Comprehensive analysis of CpG islands in human chromosomes 21 and 22. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:3740-3745.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 3740-3745
-
-
Takai, D.1
Jones, P.A.2
-
11
-
-
15744401773
-
Eukaryotic cytosine methyltransferases
-
Goll M.G., Bestor T.H. Eukaryotic cytosine methyltransferases. Annu. Rev. Biochem. 2005, 74:481-514.
-
(2005)
Annu. Rev. Biochem.
, vol.74
, pp. 481-514
-
-
Goll, M.G.1
Bestor, T.H.2
-
12
-
-
0030840954
-
Cytosine methylation and the ecology of intragenomic parasites
-
Yoder J.A., Walsh C.P., Bestor T.H. Cytosine methylation and the ecology of intragenomic parasites. Trends Genet. 1997, 13:335-340.
-
(1997)
Trends Genet.
, vol.13
, pp. 335-340
-
-
Yoder, J.A.1
Walsh, C.P.2
Bestor, T.H.3
-
13
-
-
0242584454
-
Chromosomal instability and tumors promoted by DNA hypomethylation
-
Eden A., Gaudet F., Waghmare A., Jaenisch R. Chromosomal instability and tumors promoted by DNA hypomethylation. Science 2003, 300:455.
-
(2003)
Science
, vol.300
, pp. 455
-
-
Eden, A.1
Gaudet, F.2
Waghmare, A.3
Jaenisch, R.4
-
14
-
-
33749037187
-
Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers
-
Rodriguez J., Frigola J., Vendrell E., Risques R.A., Fraga M.F., Morales C., Moreno V., Esteller M., Capella G., Ribas M., Peinado M.A. Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers. Cancer Res. 2006, 66:8462-9468.
-
(2006)
Cancer Res.
, vol.66
, pp. 8462-9468
-
-
Rodriguez, J.1
Frigola, J.2
Vendrell, E.3
Risques, R.A.4
Fraga, M.F.5
Morales, C.6
Moreno, V.7
Esteller, M.8
Capella, G.9
Ribas, M.10
Peinado, M.A.11
-
15
-
-
0024673303
-
CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation
-
Iguchi-Ariga S.M., Schaffner W. CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation. Genes Dev. 1989, 3:612-619.
-
(1989)
Genes Dev.
, vol.3
, pp. 612-619
-
-
Iguchi-Ariga, S.M.1
Schaffner, W.2
-
17
-
-
0032574977
-
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
-
Nan X., Ng H.H., Johnson C.A., Laherty C.D., Turner B.M., Eisenman R.N., Bird A. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 1998, 393:386-389.
-
(1998)
Nature
, vol.393
, pp. 386-389
-
-
Nan, X.1
Ng, H.H.2
Johnson, C.A.3
Laherty, C.D.4
Turner, B.M.5
Eisenman, R.N.6
Bird, A.7
-
18
-
-
0033601073
-
Methylation-induced repression-belts, braces, and chromatin
-
Bird A.P., Wolffe A.P. Methylation-induced repression-belts, braces, and chromatin. Cell 1999, 99:451-454.
-
(1999)
Cell
, vol.99
, pp. 451-454
-
-
Bird, A.P.1
Wolffe, A.P.2
-
19
-
-
32044455298
-
Large-scale structure of genomic methylation patterns
-
Rollins R.A, Haghighi F., Edwards J.R., Das R., Zhang M.Q., Ju J., Bestor T.H. Large-scale structure of genomic methylation patterns. Genome Res. 2006, 16:157-163.
-
(2006)
Genome Res.
, vol.16
, pp. 157-163
-
-
Rollins, R.A.1
Haghighi, F.2
Edwards, J.R.3
Das, R.4
Zhang, M.Q.5
Ju, J.6
Bestor, T.H.7
-
20
-
-
0032401808
-
Aging and DNA methylation in colorectal mucosa and cancer
-
Ahuja N., Li Q., Mohan A.L., Baylin S.B., Issa J.P. Aging and DNA methylation in colorectal mucosa and cancer. Cancer Res. 1998, 58:5489-5494.
-
(1998)
Cancer Res.
, vol.58
, pp. 5489-5494
-
-
Ahuja, N.1
Li, Q.2
Mohan, A.L.3
Baylin, S.B.4
Issa, J.P.5
-
21
-
-
0028001087
-
Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon
-
Issa J.P., Ottaviano Y.L., Celano P., Hamilton S.R., Davidson N.E., Baylin S.B. Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon. Nat. Genet. 1994, 7:536-540.
-
(1994)
Nat. Genet.
, vol.7
, pp. 536-540
-
-
Issa, J.P.1
Ottaviano, Y.L.2
Celano, P.3
Hamilton, S.R.4
Davidson, N.E.5
Baylin, S.B.6
-
22
-
-
0024802174
-
Age-related methylation changes in DNA may reflect the proliferative potential of organs
-
Hoal-van Helden E.G., van Helden P.D. Age-related methylation changes in DNA may reflect the proliferative potential of organs. Mutat. Res. 1989, 219:263-266.
-
(1989)
Mutat. Res.
, vol.219
, pp. 263-266
-
-
Hoal-van Helden, E.G.1
van Helden, P.D.2
-
23
-
-
0021101229
-
The 5-methylcytosine content of DNA from human tumors
-
Gama-Sosa M.A., Slagel V.A., Trewyn R.W., Oxenhandler R., Kuo K.C., Gehrke C.W., Ehrlich M. The 5-methylcytosine content of DNA from human tumors. Nucleic Acids Res. 1983, 11:6883-6894.
-
(1983)
Nucleic Acids Res.
, vol.11
, pp. 6883-6894
-
-
Gama-Sosa, M.A.1
Slagel, V.A.2
Trewyn, R.W.3
Oxenhandler, R.4
Kuo, K.C.5
Gehrke, C.W.6
Ehrlich, M.7
-
24
-
-
0032960181
-
Cancer epigenetics comes of age
-
Jones P.A., Laird P.W. Cancer epigenetics comes of age. Nat. Genet. 1999, 21:163-167.
-
(1999)
Nat. Genet.
, vol.21
, pp. 163-167
-
-
Jones, P.A.1
Laird, P.W.2
-
25
-
-
0020699979
-
Hypomethylation distinguishes genes of some human cancers from their normal counterparts
-
Feinberg A.P., Vogelstein B. Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 1983, 301:89-92.
-
(1983)
Nature
, vol.301
, pp. 89-92
-
-
Feinberg, A.P.1
Vogelstein, B.2
-
26
-
-
0018776724
-
5-Methylcytosine content of nuclear DNA during chemical hepatocarcinogenesis and in carcinomas which result
-
Lapeyre J.N., Becker F.F. 5-Methylcytosine content of nuclear DNA during chemical hepatocarcinogenesis and in carcinomas which result. Biochem. Biophys. Res. Commun. 1979, 87:698-705.
-
(1979)
Biochem. Biophys. Res. Commun.
, vol.87
, pp. 698-705
-
-
Lapeyre, J.N.1
Becker, F.F.2
-
27
-
-
29244490041
-
Analysis of repetitive element DNA methylation by MethyLight
-
Print 2005
-
Weisenberger D.J., Campan M., Long T.I., Kim M., Woods C., Fiala E., Ehrlich M., Laird P.W. Analysis of repetitive element DNA methylation by MethyLight. Nucleic Acids Res. 2005, 33:6823-6836. Print 2005.
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 6823-6836
-
-
Weisenberger, D.J.1
Campan, M.2
Long, T.I.3
Kim, M.4
Woods, C.5
Fiala, E.6
Ehrlich, M.7
Laird, P.W.8
-
28
-
-
0031816567
-
Hypomethylation of pericentromeric DNA in breast adenocarcinomas
-
Narayan A., Ji W., Zhang X.Y., Marrogi A., Graff J.R., Baylin S.B., Ehrlich M. Hypomethylation of pericentromeric DNA in breast adenocarcinomas. Int. J. Cancer 1998, 77:833-838.
-
(1998)
Int. J. Cancer
, vol.77
, pp. 833-838
-
-
Narayan, A.1
Ji, W.2
Zhang, X.Y.3
Marrogi, A.4
Graff, J.R.5
Baylin, S.B.6
Ehrlich, M.7
-
29
-
-
0024365892
-
Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma
-
Greger V., Passarge E., Hopping W., Messmer E., Horsthemke B. Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma. Hum. Genet. 1989, 83:155-158.
-
(1989)
Hum. Genet.
, vol.83
, pp. 155-158
-
-
Greger, V.1
Passarge, E.2
Hopping, W.3
Messmer, E.4
Horsthemke, B.5
-
30
-
-
0028072991
-
Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma
-
Herman J.G., Latif F., Weng Y., Lerman M.I., Zbar B., Liu S., Samid D., Duan D.S., Gnarra J.R., Linehan W.M., et al. Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. Proc. Natl. Acad. Sci. U. S. A. 1994, 91:9700-9704.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 9700-9704
-
-
Herman, J.G.1
Latif, F.2
Weng, Y.3
Lerman, M.I.4
Zbar, B.5
Liu, S.6
Samid, D.7
Duan, D.S.8
Gnarra, J.R.9
Linehan, W.M.10
-
31
-
-
0028845142
-
Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
-
Herman J.G., Merlo A., Mao L., Lapidus R.G., Issa J.P., Davidson N.E., Sidransky D., Baylin S.B. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res. 1995, 55:4525-4530.
-
(1995)
Cancer Res.
, vol.55
, pp. 4525-4530
-
-
Herman, J.G.1
Merlo, A.2
Mao, L.3
Lapidus, R.G.4
Issa, J.P.5
Davidson, N.E.6
Sidransky, D.7
Baylin, S.B.8
-
32
-
-
0034662626
-
Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer
-
Esteller M., Sparks A., Toyota M., Sanchez-Cespedes M., Capella G., Peinado M.A., Gonzalez S., Tarafa G., Sidransky D., Meltzer S.J., Baylin S.B., Herman J.G. Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer. Cancer Res. 2000, 60:4366-4371.
-
(2000)
Cancer Res.
, vol.60
, pp. 4366-4371
-
-
Esteller, M.1
Sparks, A.2
Toyota, M.3
Sanchez-Cespedes, M.4
Capella, G.5
Peinado, M.A.6
Gonzalez, S.7
Tarafa, G.8
Sidransky, D.9
Meltzer, S.J.10
Baylin, S.B.11
Herman, J.G.12
-
33
-
-
33847763576
-
Genetic unmasking of an epigenetically silenced microRNA in human cancer cells
-
Lujambio A., Ropero S., Ballestar E., Fraga M.F., Cerrato C., Setien F., Casado S., Suarez-Gauthier A., Sanchez-Cespedes M., Git A., Spiteri I., Das P.P., Caldas C., Miska E., Esteller M. Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Res. 2007, 67:1424-1429.
-
(2007)
Cancer Res.
, vol.67
, pp. 1424-1429
-
-
Lujambio, A.1
Ropero, S.2
Ballestar, E.3
Fraga, M.F.4
Cerrato, C.5
Setien, F.6
Casado, S.7
Suarez-Gauthier, A.8
Sanchez-Cespedes, M.9
Git, A.10
Spiteri, I.11
Das, P.P.12
Caldas, C.13
Miska, E.14
Esteller, M.15
-
34
-
-
0023748414
-
Genetic alterations during colorectal-tumor development
-
Vogelstein B., Fearon E.R., Hamilton S.R., Kern S.E., Preisinger A.C., Leppert M., Nakamura Y., White R., Smits A.M., Bos J.L. Genetic alterations during colorectal-tumor development. N. Engl. J. Med. 1988, 319:525-532.
-
(1988)
N. Engl. J. Med.
, vol.319
, pp. 525-532
-
-
Vogelstein, B.1
Fearon, E.R.2
Hamilton, S.R.3
Kern, S.E.4
Preisinger, A.C.5
Leppert, M.6
Nakamura, Y.7
White, R.8
Smits, A.M.9
Bos, J.L.10
-
35
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler K.W., Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996, 87:159-170.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
36
-
-
0036753290
-
DNA methylation: a profile of methods and applications
-
634, 636-649
-
Fraga M.F., Esteller M. DNA methylation: a profile of methods and applications. Biotechniques 2002, 33:632. 634, 636-649.
-
(2002)
Biotechniques
, vol.33
, pp. 632
-
-
Fraga, M.F.1
Esteller, M.2
-
37
-
-
33947315736
-
Cancer epigenomics: DNA methylomes and histone-modification maps
-
Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat. Rev. Genet. 2007, 8:286-298.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 286-298
-
-
Esteller, M.1
-
38
-
-
34047095827
-
The human promoter methylome
-
Zilberman D. The human promoter methylome. Nat. Genet. 2007, 39:442-443.
-
(2007)
Nat. Genet.
, vol.39
, pp. 442-443
-
-
Zilberman, D.1
-
39
-
-
0021055250
-
Quantitative determination of 5-methylcytosine in DNA by reverse-phase high-performance liquid chromatography
-
Eick D., Fritz H.J., Doerfler W. Quantitative determination of 5-methylcytosine in DNA by reverse-phase high-performance liquid chromatography. Anal. Biochem. 1983, 135:165-171.
-
(1983)
Anal. Biochem.
, vol.135
, pp. 165-171
-
-
Eick, D.1
Fritz, H.J.2
Doerfler, W.3
-
40
-
-
0023583617
-
Determination of 5-methylcytosine by acid hydrolysis of DNA with hydrofluoric acid
-
Catania J., Keenan B.C., Margison G.P., Fairweather D.S. Determination of 5-methylcytosine by acid hydrolysis of DNA with hydrofluoric acid. Anal. Biochem. 1987, 167:347-351.
-
(1987)
Anal. Biochem.
, vol.167
, pp. 347-351
-
-
Catania, J.1
Keenan, B.C.2
Margison, G.P.3
Fairweather, D.S.4
-
41
-
-
0020489781
-
Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells
-
Ehrlich M., Gama-Sosa M.A., Huang L.H., Midgett R.M., Kuo K.C., McCune R.A., Gehrke C. Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells. Nucleic Acids Res. 1982, 10:2709-2721.
-
(1982)
Nucleic Acids Res.
, vol.10
, pp. 2709-2721
-
-
Ehrlich, M.1
Gama-Sosa, M.A.2
Huang, L.H.3
Midgett, R.M.4
Kuo, K.C.5
McCune, R.A.6
Gehrke, C.7
-
42
-
-
0033817101
-
Rapid quantification of DNA methylation by high performance capillary electrophoresis
-
Fraga M.F., Rodriguez R., Canal M.J. Rapid quantification of DNA methylation by high performance capillary electrophoresis. Electrophoresis 2000, 21:2990-2994.
-
(2000)
Electrophoresis
, vol.21
, pp. 2990-2994
-
-
Fraga, M.F.1
Rodriguez, R.2
Canal, M.J.3
-
43
-
-
0018370141
-
Direct detection of methylated cytosine in DNA by use of the restriction enzyme MspI
-
Cedar H., Solage A., Glaser G., Razin A. Direct detection of methylated cytosine in DNA by use of the restriction enzyme MspI. Nucleic Acids Res. 1979, 6:2125-2132.
-
(1979)
Nucleic Acids Res.
, vol.6
, pp. 2125-2132
-
-
Cedar, H.1
Solage, A.2
Glaser, G.3
Razin, A.4
-
44
-
-
0023442124
-
Gene reactivation: a tool for the isolation of mammalian DNA methylation mutants
-
Gounari F., Banks G.R., Khazaie K., Jeggo P.A., Holliday R. Gene reactivation: a tool for the isolation of mammalian DNA methylation mutants. Genes Dev. 1987, 1:899-912.
-
(1987)
Genes Dev.
, vol.1
, pp. 899-912
-
-
Gounari, F.1
Banks, G.R.2
Khazaie, K.3
Jeggo, P.A.4
Holliday, R.5
-
45
-
-
0029848618
-
The methylation pattern of a cytosine DNA-methyltransferase gene in Arabidopsis thaliana plants
-
Kutueva L.I., Ashapkin V.V., Vanyushin B.F. The methylation pattern of a cytosine DNA-methyltransferase gene in Arabidopsis thaliana plants. Biochem. Mol. Biol. Int. 1996, 40:347-353.
-
(1996)
Biochem. Mol. Biol. Int.
, vol.40
, pp. 347-353
-
-
Kutueva, L.I.1
Ashapkin, V.V.2
Vanyushin, B.F.3
-
46
-
-
0026546877
-
A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands
-
Frommer M., McDonald L.E., Millar D.S., Collis C.M., Watt F., Grigg G.W., Molloy P.L., Paul C.L. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc. Natl. Acad. Sci. U. S. A. 1992, 89:1827-1831.
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 1827-1831
-
-
Frommer, M.1
McDonald, L.E.2
Millar, D.S.3
Collis, C.M.4
Watt, F.5
Grigg, G.W.6
Molloy, P.L.7
Paul, C.L.8
-
47
-
-
0028096611
-
High sensitivity mapping of methylated cytosines
-
Clark S.J., Harrison J., Paul C.L., Frommer M. High sensitivity mapping of methylated cytosines. Nucleic Acids Res. 1994, 22:2990-2997.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 2990-2997
-
-
Clark, S.J.1
Harrison, J.2
Paul, C.L.3
Frommer, M.4
-
48
-
-
0008708115
-
Deamination of cytosine derivatives by bisulfite. Mechanism of the reaction
-
Shapiro R., DiFate V., Welcher M. Deamination of cytosine derivatives by bisulfite. Mechanism of the reaction. J. Am. Chem. Soc. 1974, 96:906-912.
-
(1974)
J. Am. Chem. Soc.
, vol.96
, pp. 906-912
-
-
Shapiro, R.1
DiFate, V.2
Welcher, M.3
-
49
-
-
0031024587
-
Active mammalian replication origins are associated with a high-density cluster of mCpG dinucleotides
-
Rein T., Zorbas H., DePamphilis M.L. Active mammalian replication origins are associated with a high-density cluster of mCpG dinucleotides. Mol. Cell. Biol. 1997, 17:416-426.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 416-426
-
-
Rein, T.1
Zorbas, H.2
DePamphilis, M.L.3
-
50
-
-
34547528183
-
DNA methylation: bisulphite modification and analysis
-
Clark S.J., Statham A., Stirzaker C., Molloy P.L., Frommer M. DNA methylation: bisulphite modification and analysis. Nat. Protoc. 2006, 1:2353-2364.
-
(2006)
Nat. Protoc.
, vol.1
, pp. 2353-2364
-
-
Clark, S.J.1
Statham, A.2
Stirzaker, C.3
Molloy, P.L.4
Frommer, M.5
-
51
-
-
0032540905
-
A sequencing method based on real-time pyrophosphate
-
Ronaghi M., Uhlen M., Nyren P. A sequencing method based on real-time pyrophosphate. Science 1998, 281:363, 365.
-
(1998)
Science
, vol.281
, pp. 363
-
-
Ronaghi, M.1
Uhlen, M.2
Nyren, P.3
-
52
-
-
0036962761
-
Evaluation of a potential epigenetic biomarker by quantitative methyl-single nucleotide polymorphism analysis
-
Uhlmann K., Brinckmann A., Toliat M.R., Ritter H., Nurnberg P. Evaluation of a potential epigenetic biomarker by quantitative methyl-single nucleotide polymorphism analysis. Electrophoresis 2002, 23:4072-4079.
-
(2002)
Electrophoresis
, vol.23
, pp. 4072-4079
-
-
Uhlmann, K.1
Brinckmann, A.2
Toliat, M.R.3
Ritter, H.4
Nurnberg, P.5
-
53
-
-
0029843950
-
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands
-
Herman J.G., Graff J.R., Myohanen S., Nelkin B.D., Baylin S.B. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:9821-9826.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
54
-
-
0034654669
-
MethyLight: a high-throughput assay to measure DNA methylation
-
Eads C.A., Danenberg K.D., Kawakami K., Saltz L.B., Blake C., Shibata D., Danenberg P.V., Laird P.W. MethyLight: a high-throughput assay to measure DNA methylation. Nucleic Acids Res. 2000, 28:E32.
-
(2000)
Nucleic Acids Res.
, vol.28
-
-
Eads, C.A.1
Danenberg, K.D.2
Kawakami, K.3
Saltz, L.B.4
Blake, C.5
Shibata, D.6
Danenberg, P.V.7
Laird, P.W.8
-
55
-
-
24044468413
-
Headloop suppression PCR and its application to selective amplification of methylated DNA sequences
-
Rand K.N., Ho T., Qu W., Mitchell S.M., White R., Clark S.J., Molloy P.L. Headloop suppression PCR and its application to selective amplification of methylated DNA sequences. Nucleic Acids Res. 2005, 33:e127.
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Rand, K.N.1
Ho, T.2
Qu, W.3
Mitchell, S.M.4
White, R.5
Clark, S.J.6
Molloy, P.L.7
-
56
-
-
0034949862
-
In-tube DNA methylation profiling by fluorescence melting curve analysis
-
Worm J., Aggerholm A., Guldberg P. In-tube DNA methylation profiling by fluorescence melting curve analysis. Clin. Chem. 2001, 47:1183-1189.
-
(2001)
Clin. Chem.
, vol.47
, pp. 1183-1189
-
-
Worm, J.1
Aggerholm, A.2
Guldberg, P.3
-
57
-
-
0030825309
-
COBRA: a sensitive and quantitative DNA methylation assay
-
Xiong Z., Laird P.W. COBRA: a sensitive and quantitative DNA methylation assay. Nucleic Acids Res. 1997, 25:2532-2534.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 2532-2534
-
-
Xiong, Z.1
Laird, P.W.2
-
58
-
-
27644548948
-
Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry
-
Ehrich M., Nelson M.R., Stanssens P., Zabeau M., Liloglou T., Xinarianos G., Cantor C.R., Field J.K., van den Boom D. Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:15785-15790.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 15785-15790
-
-
Ehrich, M.1
Nelson, M.R.2
Stanssens, P.3
Zabeau, M.4
Liloglou, T.5
Xinarianos, G.6
Cantor, C.R.7
Field, J.K.8
van den Boom, D.9
-
59
-
-
16544362680
-
Rapid analysis of CpG methylation patterns using RNase T1 cleavage and MALDI-TOF
-
Schatz P., Dietrich D., Schuster M. Rapid analysis of CpG methylation patterns using RNase T1 cleavage and MALDI-TOF. Nucleic Acids Res. 2004, 32:e167.
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Schatz, P.1
Dietrich, D.2
Schuster, M.3
-
60
-
-
2342529185
-
DNA analysis by MALDI-TOF mass spectrometry
-
Gut I.G. DNA analysis by MALDI-TOF mass spectrometry. Hum. Mutat. 2004, 23:437-441.
-
(2004)
Hum. Mutat.
, vol.23
, pp. 437-441
-
-
Gut, I.G.1
-
61
-
-
0026052179
-
A genomic scanning method for higher organisms using restriction sites as landmarks
-
Hatada I., Hayashizaki Y., Hirotsune S., Komatsubara H., Mukai T. A genomic scanning method for higher organisms using restriction sites as landmarks. Proc. Natl. Acad. Sci. U. S. A. 1991, 88:9523-9527.
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, pp. 9523-9527
-
-
Hatada, I.1
Hayashizaki, Y.2
Hirotsune, S.3
Komatsubara, H.4
Mukai, T.5
-
62
-
-
0033563165
-
Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification
-
Toyota M., Ho C., Ahuja N., Jair K.W., Li Q., Ohe-Toyota M., Baylin S.B., Issa J.P. Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification. Cancer Res. 1999, 59:2307-2312.
-
(1999)
Cancer Res.
, vol.59
, pp. 2307-2312
-
-
Toyota, M.1
Ho, C.2
Ahuja, N.3
Jair, K.W.4
Li, Q.5
Ohe-Toyota, M.6
Baylin, S.B.7
Issa, J.P.8
-
63
-
-
0027468779
-
Cloning the differences between two complex genomes
-
Lisitsyn N., Wigler M. Cloning the differences between two complex genomes. Science 1993, 259:946-951.
-
(1993)
Science
, vol.259
, pp. 946-951
-
-
Lisitsyn, N.1
Wigler, M.2
-
64
-
-
34948830291
-
High-throughput methylation profiling by MCA coupled to CpG island microarray
-
Estecio M.R., Yan P.S., Ibrahim A.E., Tellez C.S., Shen L., Huang T.H., Issa J.P. High-throughput methylation profiling by MCA coupled to CpG island microarray. Genome Res. 2007, 17:1529-1536.
-
(2007)
Genome Res.
, vol.17
, pp. 1529-1536
-
-
Estecio, M.R.1
Yan, P.S.2
Ibrahim, A.E.3
Tellez, C.S.4
Shen, L.5
Huang, T.H.6
Issa, J.P.7
-
65
-
-
18844465619
-
Methylome profiling of cancer cells by amplification of inter-methylated sites (AIMS)
-
Frigola J., Ribas M., Risques R.A., Peinado M.A. Methylome profiling of cancer cells by amplification of inter-methylated sites (AIMS). Nucleic Acids Res. 2002, 30:e28.
-
(2002)
Nucleic Acids Res.
, vol.30
-
-
Frigola, J.1
Ribas, M.2
Risques, R.A.3
Peinado, M.A.4
-
66
-
-
39449103319
-
Genome-wide tracking of unmethylated DNA Alu repeats in normal and cancer cells
-
Rodriguez J., Vives L., Jorda M., Morales C., Munoz M., Vendrell E., Peinado M.A. Genome-wide tracking of unmethylated DNA Alu repeats in normal and cancer cells. Nucleic Acids Res. 2008, 36:770-784.
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 770-784
-
-
Rodriguez, J.1
Vives, L.2
Jorda, M.3
Morales, C.4
Munoz, M.5
Vendrell, E.6
Peinado, M.A.7
-
67
-
-
0028340280
-
Purification of CpG islands using a methylated DNA binding column
-
Cross S.H., Charlton J.A., Nan X., Bird A.P. Purification of CpG islands using a methylated DNA binding column. Nat. Genet. 1994, 6:236-244.
-
(1994)
Nat. Genet.
, vol.6
, pp. 236-244
-
-
Cross, S.H.1
Charlton, J.A.2
Nan, X.3
Bird, A.P.4
-
68
-
-
0033020727
-
Isolation of DNA fragments associated with methylated CpG islands in human adenocarcinomas of the lung using a methylated DNA binding column and denaturing gradient gel electrophoresis
-
Shiraishi M., Chuu Y.H., Sekiya T. Isolation of DNA fragments associated with methylated CpG islands in human adenocarcinomas of the lung using a methylated DNA binding column and denaturing gradient gel electrophoresis. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:2913-2918.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 2913-2918
-
-
Shiraishi, M.1
Chuu, Y.H.2
Sekiya, T.3
-
69
-
-
0033047813
-
Methylation profiling of CpG islands in human breast cancer cells
-
Huang T.H., Perry M.R., Laux D.E. Methylation profiling of CpG islands in human breast cancer cells. Hum. Mol. Genet. 1999, 8:459-470.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 459-470
-
-
Huang, T.H.1
Perry, M.R.2
Laux, D.E.3
-
70
-
-
0034051419
-
CpG island arrays: an application toward deciphering epigenetic signatures of breast cancer
-
Yan P.S., Perry M.R., Laux D.E., Asare A.L., Caldwell C.W., Huang T.H. CpG island arrays: an application toward deciphering epigenetic signatures of breast cancer. Clin. Cancer Res. 2000, 6:1432-1438.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 1432-1438
-
-
Yan, P.S.1
Perry, M.R.2
Laux, D.E.3
Asare, A.L.4
Caldwell, C.W.5
Huang, T.H.6
-
71
-
-
10044243603
-
Epigenomic changes during leukemia cell differentiation: analysis of histone acetylation and cytosine methylation using CpG island microarrays
-
Nouzova M., Holtan N., Oshiro M.M., Isett R.B., Munoz-Rodriguez J.L., List A.F., Narro M.L., Miller S.J., Merchant N.C., Futscher B.W. Epigenomic changes during leukemia cell differentiation: analysis of histone acetylation and cytosine methylation using CpG island microarrays. J. Pharmacol. Exp. Ther. 2004, 311:968-981.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.311
, pp. 968-981
-
-
Nouzova, M.1
Holtan, N.2
Oshiro, M.M.3
Isett, R.B.4
Munoz-Rodriguez, J.L.5
List, A.F.6
Narro, M.L.7
Miller, S.J.8
Merchant, N.C.9
Futscher, B.W.10
-
72
-
-
0036144883
-
Methylation-specific oligonucleotide microarray: a new potential for high-throughput methylation analysis
-
Gitan R.S., Shi H., Chen C.M., Yan P.S., Huang T.H. Methylation-specific oligonucleotide microarray: a new potential for high-throughput methylation analysis. Genome Res. 2002, 12:158-164.
-
(2002)
Genome Res.
, vol.12
, pp. 158-164
-
-
Gitan, R.S.1
Shi, H.2
Chen, C.M.3
Yan, P.S.4
Huang, T.H.5
-
73
-
-
33749032436
-
A profile of methyl-CpG binding domain protein occupancy of hypermethylated promoter CpG islands of tumor suppressor genes in human cancer
-
Lopez-Serra L., Ballestar E., Fraga M.F., Alaminos M., Setien F., Esteller M. A profile of methyl-CpG binding domain protein occupancy of hypermethylated promoter CpG islands of tumor suppressor genes in human cancer. Cancer Res. 2006, 66:8342-8346.
-
(2006)
Cancer Res.
, vol.66
, pp. 8342-8346
-
-
Lopez-Serra, L.1
Ballestar, E.2
Fraga, M.F.3
Alaminos, M.4
Setien, F.5
Esteller, M.6
-
74
-
-
0348134871
-
Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer
-
Ballestar E., Paz M.F., Valle L., Wei S., Fraga M.F., Espada J., Cigudosa J.C., Huang T.H., Esteller M. Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer. EMBO J. 2003, 22:6335-6345.
-
(2003)
EMBO J.
, vol.22
, pp. 6335-6345
-
-
Ballestar, E.1
Paz, M.F.2
Valle, L.3
Wei, S.4
Fraga, M.F.5
Espada, J.6
Cigudosa, J.C.7
Huang, T.H.8
Esteller, M.9
-
75
-
-
23044514626
-
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
-
Weber M., Davies J.J., Wittig D., Oakeley E.J., Haase M., Lam W.L., Schubeler D. Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nat. Genet. 2005, 37:853-862.
-
(2005)
Nat. Genet.
, vol.37
, pp. 853-862
-
-
Weber, M.1
Davies, J.J.2
Wittig, D.3
Oakeley, E.J.4
Haase, M.5
Lam, W.L.6
Schubeler, D.7
-
76
-
-
0036613250
-
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
-
Suzuki H., Gabrielson E., Chen W., Anbazhagan R., van Engeland M., Weijenberg M.P., Herman J.G., Baylin S.B. A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. Nat. Genet. 2002, 31:141-149.
-
(2002)
Nat. Genet.
, vol.31
, pp. 141-149
-
-
Suzuki, H.1
Gabrielson, E.2
Chen, W.3
Anbazhagan, R.4
van Engeland, M.5
Weijenberg, M.P.6
Herman, J.G.7
Baylin, S.B.8
-
77
-
-
33750953227
-
Whole-genome re-sequencing
-
Bentley D.R. Whole-genome re-sequencing. Curr. Opin. Genet. Dev. 2006, 16:545-552.
-
(2006)
Curr. Opin. Genet. Dev.
, vol.16
, pp. 545-552
-
-
Bentley, D.R.1
-
78
-
-
24044455869
-
Genome sequencing in microfabricated high-density picolitre reactors
-
Margulies M., Egholm M., Altman W.E., Attiya S., Bader J.S., Bemben L.A., Berka J., Braverman M.S., Chen Y.J., Chen Z., Dewell S.B., Du L., Fierro J.M., Gomes X.V., Godwin B.C., He W., Helgesen S., Ho C.H., Irzyk G.P., Jando S.C., Alenquer M.L., Jarvie T.P., Jirage K.B., Kim J.B., Knight J.R., Lanza J.R., Leamon J.H., Lefkowitz S.M., Lei M., Li J., Lohman K.L., Lu H., Makhijani V.B., McDade K.E., McKenna M.P., Myers E.W., Nickerson E., Nobile J.R., Plant R., Puc B.P., Ronan M.T., Roth G.T., Sarkis G.J., Simons J.F., Simpson J.W., Srinivasan M., Tartaro K.R., Tomasz A., Vogt K.A., Volkmer G.A., Wang S.H., Wang Y., Weiner M.P., Yu P., Begley R.F., Rothberg J.M. Genome sequencing in microfabricated high-density picolitre reactors. Nature 2005, 437:376-380.
-
(2005)
Nature
, vol.437
, pp. 376-380
-
-
Margulies, M.1
Egholm, M.2
Altman, W.E.3
Attiya, S.4
Bader, J.S.5
Bemben, L.A.6
Berka, J.7
Braverman, M.S.8
Chen, Y.J.9
Chen, Z.10
Dewell, S.B.11
Du, L.12
Fierro, J.M.13
Gomes, X.V.14
Godwin, B.C.15
He, W.16
Helgesen, S.17
Ho, C.H.18
Irzyk, G.P.19
Jando, S.C.20
Alenquer, M.L.21
Jarvie, T.P.22
Jirage, K.B.23
Kim, J.B.24
Knight, J.R.25
Lanza, J.R.26
Leamon, J.H.27
Lefkowitz, S.M.28
Lei, M.29
Li, J.30
Lohman, K.L.31
Lu, H.32
Makhijani, V.B.33
McDade, K.E.34
McKenna, M.P.35
Myers, E.W.36
Nickerson, E.37
Nobile, J.R.38
Plant, R.39
Puc, B.P.40
Ronan, M.T.41
Roth, G.T.42
Sarkis, G.J.43
Simons, J.F.44
Simpson, J.W.45
Srinivasan, M.46
Tartaro, K.R.47
Tomasz, A.48
Vogt, K.A.49
Volkmer, G.A.50
Wang, S.H.51
Wang, Y.52
Weiner, M.P.53
Yu, P.54
Begley, R.F.55
Rothberg, J.M.56
more..
-
79
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister R., Pelizzola M., Dowen R.H., Hawkins R.D., Hon G., Tonti-Filippini J., Nery J.R., Lee L., Ye Z., Ngo Q.M., Edsall L., Antosiewicz-Bourget J., Stewart R., Ruotti V., Millar A.H., Thomson J.A., Ren B., Ecker J.R. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 2009, 462:315-322.
-
(2009)
Nature
, vol.462
, pp. 315-322
-
-
Lister, R.1
Pelizzola, M.2
Dowen, R.H.3
Hawkins, R.D.4
Hon, G.5
Tonti-Filippini, J.6
Nery, J.R.7
Lee, L.8
Ye, Z.9
Ngo, Q.M.10
Edsall, L.11
Antosiewicz-Bourget, J.12
Stewart, R.13
Ruotti, V.14
Millar, A.H.15
Thomson, J.A.16
Ren, B.17
Ecker, J.R.18
-
80
-
-
77649267695
-
-
Dynamic changes in the human methylome during differentiation, Genome Res. 20 (2010) 320-331
-
L. Laurent, E. Wong, G. Li, T. Huynh, A. Tsirigos, C.T. Ong, H.M. Low, K.W. Kin Sung, I. Rigoutsos, J. Loring, C.L. Wei, Dynamic changes in the human methylome during differentiation, Genome Res. 20 (2010) 320-331.
-
(2010)
-
-
Laurent, L.1
Wong, E.2
Li, G.3
Huynh, T.4
Tsirigos, A.5
Ong, C.T.6
Low, H.M.7
Kin Sung, K.W.8
Rigoutsos, I.9
Loring, J.10
Wei, C.L.11
-
81
-
-
38049073696
-
Massively parallel bisulphite pyrosequencing reveals the molecular complexity of breast cancer-associated cytosine-methylation patterns obtained from tissue and serum DNA
-
Korshunova Y., Maloney R.K., Lakey N., Citek R.W., Bacher B., Budiman A., Ordway J.M., McCombie W.R., Leon J., Jeddeloh J.A., McPherson J.D. Massively parallel bisulphite pyrosequencing reveals the molecular complexity of breast cancer-associated cytosine-methylation patterns obtained from tissue and serum DNA. Genome Res. 2008, 18:19-29.
-
(2008)
Genome Res.
, vol.18
, pp. 19-29
-
-
Korshunova, Y.1
Maloney, R.K.2
Lakey, N.3
Citek, R.W.4
Bacher, B.5
Budiman, A.6
Ordway, J.M.7
McCombie, W.R.8
Leon, J.9
Jeddeloh, J.A.10
McPherson, J.D.11
-
82
-
-
58549110052
-
Genome-wide high throughput analysis of DNA methylation in eukaryotes
-
Pomraning K.R., Smith K.M., Freitag M. Genome-wide high throughput analysis of DNA methylation in eukaryotes. Methods 2008.
-
(2008)
Methods
-
-
Pomraning, K.R.1
Smith, K.M.2
Freitag, M.3
-
83
-
-
46949098742
-
A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis
-
Down T.A., Rakyan V.K., Turner D.J., Flicek P., Li H., Kulesha E., Graf S., Johnson N., Herrero J., Tomazou E.M., Thorne N.P., Backdahl L., Herberth M., Howe K.L., Jackson D.K., Miretti M.M., Marioni J.C., Birney E., Hubbard T.J., Durbin R., Tavare S., Beck S. A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis. Nat. Biotechnol. 2008, 26:779-785.
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 779-785
-
-
Down, T.A.1
Rakyan, V.K.2
Turner, D.J.3
Flicek, P.4
Li, H.5
Kulesha, E.6
Graf, S.7
Johnson, N.8
Herrero, J.9
Tomazou, E.M.10
Thorne, N.P.11
Backdahl, L.12
Herberth, M.13
Howe, K.L.14
Jackson, D.K.15
Miretti, M.M.16
Marioni, J.C.17
Birney, E.18
Hubbard, T.J.19
Durbin, R.20
Tavare, S.21
Beck, S.22
more..
-
84
-
-
0343621494
-
Aberrant CpG-island methylation has non-random and tumour-type-specific patterns
-
Costello J.F., Fruhwald M.C., Smiraglia D.J., Rush L.J., Robertson G.P., Gao X., Wright F.A., Feramisco J.D., Peltomaki P., Lang J.C., Schuller D.E., Yu L., Bloomfield C.D., Caligiuri M.A., Yates A., Nishikawa R., Su Huang H., Petrelli N.J., Zhang X., O'Dorisio M.S., Held W.A., Cavenee W.K., Plass C. Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat. Genet. 2000, 24:132-138.
-
(2000)
Nat. Genet.
, vol.24
, pp. 132-138
-
-
Costello, J.F.1
Fruhwald, M.C.2
Smiraglia, D.J.3
Rush, L.J.4
Robertson, G.P.5
Gao, X.6
Wright, F.A.7
Feramisco, J.D.8
Peltomaki, P.9
Lang, J.C.10
Schuller, D.E.11
Yu, L.12
Bloomfield, C.D.13
Caligiuri, M.A.14
Yates, A.15
Nishikawa, R.16
Su Huang, H.17
Petrelli, N.J.18
Zhang, X.19
O'Dorisio, M.S.20
Held, W.A.21
Cavenee, W.K.22
Plass, C.23
more..
-
85
-
-
0035870248
-
A gene hypermethylation profile of human cancer
-
Esteller M., Corn P.G., Baylin S.B., Herman J.G. A gene hypermethylation profile of human cancer. Cancer Res. 2001, 61:3225-3229.
-
(2001)
Cancer Res.
, vol.61
, pp. 3225-3229
-
-
Esteller, M.1
Corn, P.G.2
Baylin, S.B.3
Herman, J.G.4
-
86
-
-
19244370208
-
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis
-
Esteller M., Toyota M., Sanchez-Cespedes M., Capella G., Peinado M.A., Watkins D.N., Issa J.P., Sidransky D., Baylin S.B., Herman J.G. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis. Cancer Res. 2000, 60:2368-2371.
-
(2000)
Cancer Res.
, vol.60
, pp. 2368-2371
-
-
Esteller, M.1
Toyota, M.2
Sanchez-Cespedes, M.3
Capella, G.4
Peinado, M.A.5
Watkins, D.N.6
Issa, J.P.7
Sidransky, D.8
Baylin, S.B.9
Herman, J.G.10
-
87
-
-
0031017268
-
Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines
-
Kane M.F., Loda M., Gaida G.M., Lipman J., Mishra R., Goldman H., Jessup J.M., Kolodner R. Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res. 1997, 57:808-811.
-
(1997)
Cancer Res.
, vol.57
, pp. 808-811
-
-
Kane, M.F.1
Loda, M.2
Gaida, G.M.3
Lipman, J.4
Mishra, R.5
Goldman, H.6
Jessup, J.M.7
Kolodner, R.8
-
88
-
-
0032468051
-
Hypomethylation of the metastasis-associated S100A4 gene correlates with gene activation in human colon adenocarcinoma cell lines
-
Nakamura N., Takenaga K. Hypomethylation of the metastasis-associated S100A4 gene correlates with gene activation in human colon adenocarcinoma cell lines. Clin. Exp. Metastasis 1998, 16:471-479.
-
(1998)
Clin. Exp. Metastasis
, vol.16
, pp. 471-479
-
-
Nakamura, N.1
Takenaga, K.2
-
89
-
-
12744271900
-
Differential DNA hypermethylation and hypomethylation signatures in colorectal cancer
-
Frigola J., Sole X., Paz M.F., Moreno V., Esteller M., Capella G., Peinado M.A. Differential DNA hypermethylation and hypomethylation signatures in colorectal cancer. Hum. Mol. Genet. 2005, 14:319-326.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 319-326
-
-
Frigola, J.1
Sole, X.2
Paz, M.F.3
Moreno, V.4
Esteller, M.5
Capella, G.6
Peinado, M.A.7
-
90
-
-
57349138824
-
A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer
-
Ogino S., Nosho K., Kirkner G.J., Kawasaki T., Chan A.T., Schernhammer E.S., Giovannucci E.L., Fuchs C.S. A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer. J. Natl. Cancer Inst. 2008, 100:1734-1738.
-
(2008)
J. Natl. Cancer Inst.
, vol.100
, pp. 1734-1738
-
-
Ogino, S.1
Nosho, K.2
Kirkner, G.J.3
Kawasaki, T.4
Chan, A.T.5
Schernhammer, E.S.6
Giovannucci, E.L.7
Fuchs, C.S.8
-
91
-
-
0034326238
-
Predicting lung cancer by detecting aberrant promoter methylation in sputum
-
Palmisano W.A., Divine K.K., Saccomanno G., Gilliland F.D., Baylin S.B., Herman J.G., Belinsky S.A. Predicting lung cancer by detecting aberrant promoter methylation in sputum. Cancer Res. 2000, 60:5954-5958.
-
(2000)
Cancer Res.
, vol.60
, pp. 5954-5958
-
-
Palmisano, W.A.1
Divine, K.K.2
Saccomanno, G.3
Gilliland, F.D.4
Baylin, S.B.5
Herman, J.G.6
Belinsky, S.A.7
-
92
-
-
0034808413
-
Molecular detection of prostate cancer in urine by GSTP1 hypermethylation
-
Cairns P., Esteller M., Herman J.G., Schoenberg M., Jeronimo C., Sanchez-Cespedes M., Chow N.H., Grasso M., Wu L., Westra W.B., Sidransky D. Molecular detection of prostate cancer in urine by GSTP1 hypermethylation. Clin. Cancer Res. 2001, 7:2727-2730.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 2727-2730
-
-
Cairns, P.1
Esteller, M.2
Herman, J.G.3
Schoenberg, M.4
Jeronimo, C.5
Sanchez-Cespedes, M.6
Chow, N.H.7
Grasso, M.8
Wu, L.9
Westra, W.B.10
Sidransky, D.11
-
93
-
-
0037068358
-
Reactivating the expression of methylation silenced genes in human cancer
-
Karpf A.R., Jones D.A. Reactivating the expression of methylation silenced genes in human cancer. Oncogene 2002, 21:5496-5503.
-
(2002)
Oncogene
, vol.21
, pp. 5496-5503
-
-
Karpf, A.R.1
Jones, D.A.2
-
94
-
-
37549066863
-
Discovery of epigenetically silenced genes by methylated DNA immunoprecipitation in colon cancer cells
-
Jacinto F.V., Ballestar E., Ropero S., Esteller M. Discovery of epigenetically silenced genes by methylated DNA immunoprecipitation in colon cancer cells. Cancer Res. 2007, 67:11481-11486.
-
(2007)
Cancer Res.
, vol.67
, pp. 11481-11486
-
-
Jacinto, F.V.1
Ballestar, E.2
Ropero, S.3
Esteller, M.4
-
95
-
-
27744570398
-
Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy
-
Frigola J., Muñoz M., Clark S.J., Moreno V., Capella G., Peinado M.A. Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy. Oncogene 2005, 24:7320-7326.
-
(2005)
Oncogene
, vol.24
, pp. 7320-7326
-
-
Frigola, J.1
Muñoz, M.2
Clark, S.J.3
Moreno, V.4
Capella, G.5
Peinado, M.A.6
-
96
-
-
0034626988
-
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
-
Esteller M., Garcia-Foncillas J., Andion E., Goodman S.N., Hidalgo O.F., Vanaclocha V., Baylin S.B., Herman J.G. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N. Engl. J. Med. 2000, 343:1350-1354.
-
(2000)
N. Engl. J. Med.
, vol.343
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
Goodman, S.N.4
Hidalgo, O.F.5
Vanaclocha, V.6
Baylin, S.B.7
Herman, J.G.8
-
97
-
-
0028333951
-
Ubiquitous and tenacious methylation of the CpG site in codon 248 of the p53 gene may explain its frequent appearance as a mutational hot spot in human cancer
-
Magewu A.N., Jones P.A. Ubiquitous and tenacious methylation of the CpG site in codon 248 of the p53 gene may explain its frequent appearance as a mutational hot spot in human cancer. Mol. Cell. Biol. 1994, 14:4225-4232.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 4225-4232
-
-
Magewu, A.N.1
Jones, P.A.2
-
98
-
-
0036152815
-
Detection of aberrant p16 methylation in the serum of colorectal cancer patients
-
Zou H.Z., Yu B.M., Wang Z.W., Sun J.Y., Cang H., Gao F., Li D.H., Zhao R., Feng G.G., Yi J. Detection of aberrant p16 methylation in the serum of colorectal cancer patients. Clin. Cancer Res. 2002, 8:188-191.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 188-191
-
-
Zou, H.Z.1
Yu, B.M.2
Wang, Z.W.3
Sun, J.Y.4
Cang, H.5
Gao, F.6
Li, D.H.7
Zhao, R.8
Feng, G.G.9
Yi, J.10
-
99
-
-
67349175004
-
Long-range epigenetic silencing at 2q14.2 affects most human colorectal cancers and may have application as a non-invasive biomarker of disease
-
Mayor R., Casadome L., Azuara D., Moreno V., Clark S.J., Capella G., Peinado M.A. Long-range epigenetic silencing at 2q14.2 affects most human colorectal cancers and may have application as a non-invasive biomarker of disease. Br. J. Cancer 2009, 100:1534-1539.
-
(2009)
Br. J. Cancer
, vol.100
, pp. 1534-1539
-
-
Mayor, R.1
Casadome, L.2
Azuara, D.3
Moreno, V.4
Clark, S.J.5
Capella, G.6
Peinado, M.A.7
-
100
-
-
0035863495
-
K-ras and p16 aberrations confer poor prognosis in human colorectal cancer
-
Esteller M., Gonzalez S., Risques R.A., Marcuello E., Mangues R., Germa J.R., Herman J.G., Capella G., Peinado M.A. K-ras and p16 aberrations confer poor prognosis in human colorectal cancer. J. Clin. Oncol. 2001, 19:299-304.
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 299-304
-
-
Esteller, M.1
Gonzalez, S.2
Risques, R.A.3
Marcuello, E.4
Mangues, R.5
Germa, J.R.6
Herman, J.G.7
Capella, G.8
Peinado, M.A.9
-
101
-
-
0037055554
-
Detection of free-circulating tumor-associated DNA in plasma of colorectal cancer patients and its association with prognosis
-
Lecomte T., Berger A., Zinzindohoue F., Micard S., Landi B., Blons H., Beaune P., Cugnenc P.H., Laurent-Puig P. Detection of free-circulating tumor-associated DNA in plasma of colorectal cancer patients and its association with prognosis. Int. J. Cancer 2002, 100:542-548.
-
(2002)
Int. J. Cancer
, vol.100
, pp. 542-548
-
-
Lecomte, T.1
Berger, A.2
Zinzindohoue, F.3
Micard, S.4
Landi, B.5
Blons, H.6
Beaune, P.7
Cugnenc, P.H.8
Laurent-Puig, P.9
-
102
-
-
9344244741
-
Epigenetic inactivation of ID4 in colorectal carcinomas correlates with poor differentiation and unfavorable prognosis
-
Umetani N., Takeuchi H., Fujimoto A., Shinozaki M., Bilchik A.J., Hoon D.S. Epigenetic inactivation of ID4 in colorectal carcinomas correlates with poor differentiation and unfavorable prognosis. Clin. Cancer Res. 2004, 10:7475-7483.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 7475-7483
-
-
Umetani, N.1
Takeuchi, H.2
Fujimoto, A.3
Shinozaki, M.4
Bilchik, A.J.5
Hoon, D.S.6
-
103
-
-
36749025213
-
Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer
-
Shen L., Toyota M., Kondo Y., Lin E., Zhang L., Guo Y., Hernandez N.S., Chen X., Ahmed S., Konishi K., Hamilton S.R., Issa J.P. Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:18654-18659.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 18654-18659
-
-
Shen, L.1
Toyota, M.2
Kondo, Y.3
Lin, E.4
Zhang, L.5
Guo, Y.6
Hernandez, N.S.7
Chen, X.8
Ahmed, S.9
Konishi, K.10
Hamilton, S.R.11
Issa, J.P.12
-
104
-
-
0033985151
-
Hypermethylation-associated inactivation of p14(ARF) is independent of p16(INK4a) methylation and p53 mutational status
-
Esteller M., Tortola S., Toyota M., Capella G., Peinado M.A., Baylin S.B., Herman J.G. Hypermethylation-associated inactivation of p14(ARF) is independent of p16(INK4a) methylation and p53 mutational status. Cancer Res. 2000, 60:129-133.
-
(2000)
Cancer Res.
, vol.60
, pp. 129-133
-
-
Esteller, M.1
Tortola, S.2
Toyota, M.3
Capella, G.4
Peinado, M.A.5
Baylin, S.B.6
Herman, J.G.7
-
105
-
-
48849098718
-
Expression of the hMLH1 gene is a possible predictor for the clinical response to 5-fluorouracil after a surgical resection in colorectal cancer
-
Ide T., Kitajima Y., Ohtaka K., Mitsuno M., Nakafusa Y., Miyazaki K. Expression of the hMLH1 gene is a possible predictor for the clinical response to 5-fluorouracil after a surgical resection in colorectal cancer. Oncol. Rep. 2008, 19:1571-1576.
-
(2008)
Oncol. Rep.
, vol.19
, pp. 1571-1576
-
-
Ide, T.1
Kitajima, Y.2
Ohtaka, K.3
Mitsuno, M.4
Nakafusa, Y.5
Miyazaki, K.6
-
106
-
-
0029762815
-
DNA repair: enzymatic mechanisms and relevance to drug response
-
Chaney S.G., Sancar A. DNA repair: enzymatic mechanisms and relevance to drug response. J. Natl. Cancer Inst. 1996, 88:1346-1360.
-
(1996)
J. Natl. Cancer Inst.
, vol.88
, pp. 1346-1360
-
-
Chaney, S.G.1
Sancar, A.2
-
107
-
-
0033955906
-
A defect in a single allele of the Mlh1 gene causes dissociation of the killing and tumorigenic actions of an alkylating carcinogen in methyltransferase-deficient mice
-
Kawate H., Itoh R., Sakumi K., Nakabeppu Y., Tsuzuki T., Ide F., Ishikawa T., Noda T., Nawata H., Sekiguchi M. A defect in a single allele of the Mlh1 gene causes dissociation of the killing and tumorigenic actions of an alkylating carcinogen in methyltransferase-deficient mice. Carcinogenesis 2000, 21:301-305.
-
(2000)
Carcinogenesis
, vol.21
, pp. 301-305
-
-
Kawate, H.1
Itoh, R.2
Sakumi, K.3
Nakabeppu, Y.4
Tsuzuki, T.5
Ide, F.6
Ishikawa, T.7
Noda, T.8
Nawata, H.9
Sekiguchi, M.10
-
108
-
-
0033894117
-
Aberrant methylation of the cyclooxygenase 2 CpG island in colorectal tumors
-
Toyota M., Shen L., Ohe-Toyota M., Hamilton S.R., Sinicrope F.A., Issa J.P. Aberrant methylation of the cyclooxygenase 2 CpG island in colorectal tumors. Cancer Res. 2000, 60:4044-4048.
-
(2000)
Cancer Res.
, vol.60
, pp. 4044-4048
-
-
Toyota, M.1
Shen, L.2
Ohe-Toyota, M.3
Hamilton, S.R.4
Sinicrope, F.A.5
Issa, J.P.6
-
109
-
-
17744418769
-
The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
-
Steinbach G., Lynch P.M., Phillips R.K., Wallace M.H., Hawk E., Gordon G.B., Wakabayashi N., Saunders B., Shen Y., Fujimura T., Su L.K., Levin B. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N. Engl. J. Med. 2000, 342:1946-1952.
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 1946-1952
-
-
Steinbach, G.1
Lynch, P.M.2
Phillips, R.K.3
Wallace, M.H.4
Hawk, E.5
Gordon, G.B.6
Wakabayashi, N.7
Saunders, B.8
Shen, Y.9
Fujimura, T.10
Su, L.K.11
Levin, B.12
-
110
-
-
0036314920
-
Quantitative methylation analysis using methylation-sensitive single-nucleotide primer extension (Ms-SNuPE)
-
Gonzalgo M.L, Jones P.A. Quantitative methylation analysis using methylation-sensitive single-nucleotide primer extension (Ms-SNuPE). Methods 2002, 27:128-133.
-
(2002)
Methods
, vol.27
, pp. 128-133
-
-
Gonzalgo, M.L.1
Jones, P.A.2
-
111
-
-
0032836903
-
Methylation-sensitive, single-strand conformation analysis (MS-SSCA): a rapid method to screen for and analyze methylation
-
Bianco T., Hussey D., Dobrovic A. Methylation-sensitive, single-strand conformation analysis (MS-SSCA): a rapid method to screen for and analyze methylation. Hum. Mutat. 1999, 14:289-293.
-
(1999)
Hum. Mutat.
, vol.14
, pp. 289-293
-
-
Bianco, T.1
Hussey, D.2
Dobrovic, A.3
-
112
-
-
0031050736
-
Identification and characterization of differentially methylated regions of genomic DNA by methylation-sensitive arbitrarily primed PCR
-
Gonzalgo M.L, Liang G., Spruck C.H., Zingg J.M., Rideout W.M., Jones P.A. Identification and characterization of differentially methylated regions of genomic DNA by methylation-sensitive arbitrarily primed PCR. Cancer Res. 1997, 57:594-599.
-
(1997)
Cancer Res.
, vol.57
, pp. 594-599
-
-
Gonzalgo, M.L.1
Liang, G.2
Spruck, C.H.3
Zingg, J.M.4
Rideout, W.M.5
Jones, P.A.6
-
113
-
-
58149395035
-
Bivalent domains enforce transcriptional memory of DNA methylated genes in cancer cells
-
Rodriguez J., Muñoz M., Vives L., Frangou C.G., Groudine M., Peinado M.A. Bivalent domains enforce transcriptional memory of DNA methylated genes in cancer cells. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:19809-19814.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 19809-19814
-
-
Rodriguez, J.1
Muñoz, M.2
Vives, L.3
Frangou, C.G.4
Groudine, M.5
Peinado, M.A.6
-
114
-
-
0038153876
-
SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers
-
Li H., Myeroff L., Smiraglia D., Romero M.F., Pretlow T.P., Kasturi L., Lutterbaugh J., Rerko R.M., Casey G., Issa J.P., Willis J., Willson J.K., Plass C., Markowitz S.D. SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:8412-8417.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 8412-8417
-
-
Li, H.1
Myeroff, L.2
Smiraglia, D.3
Romero, M.F.4
Pretlow, T.P.5
Kasturi, L.6
Lutterbaugh, J.7
Rerko, R.M.8
Casey, G.9
Issa, J.P.10
Willis, J.11
Willson, J.K.12
Plass, C.13
Markowitz, S.D.14
-
115
-
-
0034282986
-
The gene for a novel transmembrane protein containing epidermal growth factor and follistatin domains is frequently hypermethylated in human tumor cells
-
Liang G., Robertson K.D., Talmadge C., Sumegi J., Jones P.A. The gene for a novel transmembrane protein containing epidermal growth factor and follistatin domains is frequently hypermethylated in human tumor cells. Cancer Res. 2000, 60:4907-4912.
-
(2000)
Cancer Res.
, vol.60
, pp. 4907-4912
-
-
Liang, G.1
Robertson, K.D.2
Talmadge, C.3
Sumegi, J.4
Jones, P.A.5
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