Oncogenic Ras induces premature senescence in endothelial cells: Role of p21Cip1/Waf1

Basic Research in Cardiology

Volumn 97, Issue 2, 2002, Pages 117-124

  Spyridopoulos, Ioakim ^a   Isner, Jeffrey M ^b   Losordo, Douglas W ^b  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b ST ELIZABETH'S MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Atherosclerosis; Cell cycle; Endothelial cells; p21; Ras; Senescence

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; ONCOPROTEIN; PROTEIN P16; PROTEIN P21; PROTEIN P53; TUMOR NECROSIS FACTOR ALPHA;

ADENOVIRUS; ANIMAL CELL; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; CATTLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE PARAMETERS; CELL DEATH; CELL TRANSFORMATION; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EXPOSURE; DRUG SENSITIVITY; ENDOTHELIUM CELL; ENZYME ACTIVITY; FUNCTIONAL MORPHOLOGY; GENE OVEREXPRESSION; GROWTH INHIBITION; IN VITRO STUDY; NONHUMAN; ONCOGENE RAS; PREMATURE AGING; PROTEIN ANALYSIS; SENESCENCE; SIGNAL TRANSDUCTION; VIRUS RECOMBINANT; VIRUS REPLICATION;

ADENOVIRIDAE; ANIMALS; AORTA; APOPTOSIS; ARTERIOSCLEROSIS; CATTLE; CELL AGING; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; ENDOTHELIUM, VASCULAR; GENE EXPRESSION; PROTO-ONCOGENE PROTEINS P21(RAS);

EID: 0036118729     PISSN: 03008428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003950200001     Document Type: Article

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