메뉴 건너뛰기




Volumn 204, Issue 1, 2005, Pages 18-26

Implications of oxidative stress and hepatic cytokine (TNF-α and IL-6) response in the pathogenesis of hepatic collagenesis in chronic arsenic toxicity

Author keywords

Arsenic; Hepatotoxicity; Oxystress; Proinflammatory cytokines

Indexed keywords

ARSENIC; CARBONYL DERIVATIVE; CATALASE; COLLAGEN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; INTERLEUKIN 6; THIOL DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

EID: 15444369928     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.taap.2004.08.010     Document Type: Article
Times cited : (121)

References (69)
  • 2
    • 0008517022 scopus 로고    scopus 로고
    • Enzymatic methylation of arsenic species and other new approaches to arsenic toxicity
    • H.V. Aposhian Enzymatic methylation of arsenic species and other new approaches to arsenic toxicity Annu. Rev. Pharmacol. Toxicol. 37 1997 397 419
    • (1997) Annu. Rev. Pharmacol. Toxicol. , vol.37 , pp. 397-419
    • Aposhian, H.V.1
  • 3
    • 0000858399 scopus 로고
    • Online photooxidation for the determination of organoarsenic compounds by AAS with continuous arsine generation
    • R. Atallah, and D.A. Kalman Online photooxidation for the determination of organoarsenic compounds by AAS with continuous arsine generation Talanta 38 1991 167 173
    • (1991) Talanta , vol.38 , pp. 167-173
    • Atallah, R.1    Kalman, D.A.2
  • 4
    • 0027397539 scopus 로고
    • TNF-alpha and TGF-beta1 stimulate fibronectin synthesis and the transdifferentiation of fat storing cells in the rat liver into myofibroblast
    • M.G. Bachem, K.M. Shell, R. Melchior, J. Kroof, and A.M. Gressner TNF-alpha and TGF-beta1 stimulate fibronectin synthesis and the transdifferentiation of fat storing cells in the rat liver into myofibroblast Virchows Arch. B: Cell Pathol. 63 1993 123 130
    • (1993) Virchows Arch. B: Cell Pathol. , vol.63 , pp. 123-130
    • Bachem, M.G.1    Shell, K.M.2    Melchior, R.3    Kroof, J.4    Gressner, A.M.5
  • 5
    • 0025157647 scopus 로고
    • The pathology of hepatic iron overload: A free radical mediated process
    • B.R. Bacon, and R.S. Britton The pathology of hepatic iron overload: a free radical mediated process Hepatology 11 1990 127 137
    • (1990) Hepatology , vol.11 , pp. 127-137
    • Bacon, B.R.1    Britton, R.S.2
  • 7
    • 0018852264 scopus 로고
    • NADPH driven lipid peroxidation in rat liver nuclei and nuclear membranes
    • M.B. Baird, L.S. Birnbaum, and G.T. Sfeier NADPH driven lipid peroxidation in rat liver nuclei and nuclear membranes Arch. Biochem. Biophys. 200 1980 108 115
    • (1980) Arch. Biochem. Biophys. , vol.200 , pp. 108-115
    • Baird, M.B.1    Birnbaum, L.S.2    Sfeier, G.T.3
  • 8
    • 0013923654 scopus 로고
    • Estimation and identification of thiols in rat spleen after cysteine or glutathione treatment relevant to protection nitrogen mustards
    • C.R. Ball Estimation and identification of thiols in rat spleen after cysteine or glutathione treatment relevant to protection nitrogen mustards Biochem. Pharmacol. 15 1966 809 816
    • (1966) Biochem. Pharmacol. , vol.15 , pp. 809-816
    • Ball, C.R.1
  • 9
    • 0028311733 scopus 로고
    • Glutathione mercaptides as transport forms of metals
    • N. Ballatori Glutathione mercaptides as transport forms of metals Adv. Pharmacol. 27 1994 271 298
    • (1994) Adv. Pharmacol. , vol.27 , pp. 271-298
    • Ballatori, N.1
  • 10
    • 41049100518 scopus 로고
    • A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase
    • R.F. Beers, and I.W. Sizer A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase J. Biol. Chem. 195 1952 133
    • (1952) J. Biol. Chem. , vol.195 , pp. 133
    • Beers, R.F.1    Sizer, I.W.2
  • 13
    • 0018776894 scopus 로고
    • Hydroperoxide metabolism in mammalian organs
    • B. Chance, H. Sies, and A. Boveris Hydroperoxide metabolism in mammalian organs Physiol. Rev. 59 1979 527 605
    • (1979) Physiol. Rev. , vol.59 , pp. 527-605
    • Chance, B.1    Sies, H.2    Boveris, A.3
  • 14
    • 0025988358 scopus 로고
    • Cytoprotective effect of reduced glutathione in arsenical induced endothelial cell injury
    • W.C. Chang, S.H. Chen, H.L. Wu, G.Y. Shi, S.I. Murota, and I. Morita Cytoprotective effect of reduced glutathione in arsenical induced endothelial cell injury Toxicology 69 1991 101 110
    • (1991) Toxicology , vol.69 , pp. 101-110
    • Chang, W.C.1    Chen, S.H.2    Wu, H.L.3    Shi, G.Y.4    Murota, S.I.5    Morita, I.6
  • 15
    • 0024468325 scopus 로고
    • Stimulation of collagen gene expression by ascorbic acid in cultured human fibroblast. a role for lipid peroxidation
    • M. Chojkier, K. Houghum, and D.A. Brenner Stimulation of collagen gene expression by ascorbic acid in cultured human fibroblast. A role for lipid peroxidation J. Biol. Chem. 264 1989 16957 16962
    • (1989) J. Biol. Chem. , vol.264 , pp. 16957-16962
    • Chojkier, M.1    Houghum, K.2    Brenner, D.A.3
  • 16
    • 0035012528 scopus 로고    scopus 로고
    • In vitro effect of arsenical compounds on glutathione related enzymes
    • S. Chouchane, and T.S. Elizabeth In vitro effect of arsenical compounds on glutathione related enzymes Chem. Res. Toxicol. 14 2001 517 522
    • (2001) Chem. Res. Toxicol. , vol.14 , pp. 517-522
    • Chouchane, S.1    Elizabeth, T.S.2
  • 17
    • 0018356047 scopus 로고
    • Chronic arsenic oral intoxication as a possible etiological factor in idiopathic portal hypertension (non-cirrhotic portal fibrosis) in India
    • D.V. Datta, S.K. Mitra, P.N. Chuttani, and R.N. Chakraborti Chronic arsenic oral intoxication as a possible etiological factor in idiopathic portal hypertension (non-cirrhotic portal fibrosis) in India Gut 20 1979 378 384
    • (1979) Gut , vol.20 , pp. 378-384
    • Datta, D.V.1    Mitra, S.K.2    Chuttani, P.N.3    Chakraborti, R.N.4
  • 18
    • 0021671419 scopus 로고
    • Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes
    • D. DiMonte, D. Ross, G. Bellemo, L. Eklow, and S. Orrenius Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes Arch. Biochem. Biophys. 235 2 1984 334 342
    • (1984) Arch. Biochem. Biophys. , vol.235 , Issue.2 , pp. 334-342
    • Dimonte, D.1    Ross, D.2    Bellemo, G.3    Eklow, L.4    Orrenius, S.5
  • 19
    • 6544247909 scopus 로고
    • Fowler's solution as an etiologic agent in cirrhosis
    • M. Franklin, W.B. Bean, and R.C. Handin Fowler's solution as an etiologic agent in cirrhosis Am. J. Med. Sci. 219 1950 589 595
    • (1950) Am. J. Med. Sci. , vol.219 , pp. 589-595
    • Franklin, M.1    Bean, W.B.2    Handin, R.C.3
  • 20
    • 0030198889 scopus 로고    scopus 로고
    • Oxidation of circulating proteins in alcoholics: Role of acetaldehyde and xanthine oxidase
    • I. Grattagliano, G. Vendemiale, C. Sabba, P. Buonamico, and E. Altomare Oxidation of circulating proteins in alcoholics: role of acetaldehyde and xanthine oxidase J. Hepatol. 25 1996 28 36
    • (1996) J. Hepatol. , vol.25 , pp. 28-36
    • Grattagliano, I.1    Vendemiale, G.2    Sabba, C.3    Buonamico, P.4    Altomare, E.5
  • 21
    • 0026341256 scopus 로고
    • Characterization of fat storing cell lines derived from normal and cirrhotic livers. Differences in the productions of IL-6
    • P. Greenwel, M. Scwartz, M. Rosas, and S. Peyrol Characterization of fat storing cell lines derived from normal and cirrhotic livers. Differences in the productions of IL-6 Lab. Invest. 65 1991 644 653
    • (1991) Lab. Invest. , vol.65 , pp. 644-653
    • Greenwel, P.1    Scwartz, M.2    Rosas, M.3    Peyrol, S.4
  • 25
    • 0025862412 scopus 로고
    • Glutathione dependent biliary excretion of arsenic
    • A. Gyurasics, F. Varga, and Z. Gregus Glutathione dependent biliary excretion of arsenic Biochem. Pharmacol. 42 1991 465 468
    • (1991) Biochem. Pharmacol. , vol.42 , pp. 465-468
    • Gyurasics, A.1    Varga, F.2    Gregus, Z.3
  • 26
    • 0028068186 scopus 로고
    • Free radicals, antioxidants, and human diseases: Curiosity, cause or consequence?
    • B. Halliwell Free radicals, antioxidants, and human diseases: curiosity, cause or consequence? Lancet 344 1994 721 724
    • (1994) Lancet , vol.344 , pp. 721-724
    • Halliwell, B.1
  • 27
    • 0037011992 scopus 로고    scopus 로고
    • Elevated IL-6 during ethanol consumption acts as a potential endogenous protective cytokine against ethanol induced apoptosis in the liver: Involvement of induction of Bcl-2 and Bcl-x(L) proteins
    • F. Hong, W.H. Kim, Z. Tian, B. Jaruga, E. Ishac, X. Shen, and B. Gao Elevated IL-6 during ethanol consumption acts as a potential endogenous protective cytokine against ethanol induced apoptosis in the liver: involvement of induction of Bcl-2 and Bcl-x(L) proteins Oncogene 21 1 2002 32 43 (Jan. 3)
    • (2002) Oncogene , vol.21 , Issue.1 , pp. 32-43
    • Hong, F.1    Kim, W.H.2    Tian, Z.3    Jaruga, B.4    Ishac, E.5    Shen, X.6    Gao, B.7
  • 29
    • 0019214591 scopus 로고
    • Study on chronic toxicity of arsenic trioxide in rats with special reference to the liver damage
    • N. Ishinishi, M. Tomita, and A. Hisanga Study on chronic toxicity of arsenic trioxide in rats with special reference to the liver damage Fukuoka Acta Med. 71 1980 27 34
    • (1980) Fukuoka Acta Med. , vol.71 , pp. 27-34
    • Ishinishi, N.1    Tomita, M.2    Hisanga, A.3
  • 30
    • 0032571852 scopus 로고    scopus 로고
    • Enhancement of expression of stress proteins by agents that lower the levels of glutathione in cells
    • H. Ito, K. Okamoto, and K. Kato Enhancement of expression of stress proteins by agents that lower the levels of glutathione in cells Biochim. Biophys. Acta 29 1397(2) 1998 223 230
    • (1998) Biochim. Biophys. Acta , vol.1397 , Issue.2 , pp. 223-230
    • Ito, H.1    Okamoto, K.2    Kato, K.3
  • 31
    • 0033637264 scopus 로고    scopus 로고
    • Enhanced hepatic lipid peroxidation in patients with primary biliary cirrhosis
    • K. Kawamura, Y. Kobayashi, and E. Kageyama Enhanced hepatic lipid peroxidation in patients with primary biliary cirrhosis Am. J. Gastroenterol. 95 2000 3596
    • (2000) Am. J. Gastroenterol. , vol.95 , pp. 3596
    • Kawamura, K.1    Kobayashi, Y.2    Kageyama, E.3
  • 32
    • 0026784413 scopus 로고
    • Differential expression of keratan sulphate proteoglycans fibromodulin, lumican and aggrecan in normal and fibrotic rat liver
    • N.B. Krull, and A.M. Gressner Differential expression of keratan sulphate proteoglycans fibromodulin, lumican and aggrecan in normal and fibrotic rat liver FEBS Lett. 312 1 1992 47 52 (Nov. 2)
    • (1992) FEBS Lett. , vol.312 , Issue.1 , pp. 47-52
    • Krull, N.B.1    Gressner, A.M.2
  • 33
    • 0024312236 scopus 로고
    • Elevation of Glutathione levels and glutathione-transferase activity in arsenic resistant Chinese hamster ovary cells
    • T.C. Lee, M.L. Wei, W.J. Chang, I.C. Ho, J.F. Lo, K.Y. Jan, and H. Huang Elevation of Glutathione levels and glutathione-transferase activity in arsenic resistant Chinese hamster ovary cells In Vitro Cell. Div. Biol. 25 1989 442 448
    • (1989) In Vitro Cell. Div. Biol. , vol.25 , pp. 442-448
    • Lee, T.C.1    Wei, M.L.2    Chang, W.J.3    Ho, I.C.4    Lo, J.F.5    Jan, K.Y.6    Huang, H.7
  • 34
    • 0028838193 scopus 로고
    • Activation of HSC by TGF-alpha and collagen type I is mediated by oxidative stress through c-myb expression
    • K.S. Lee, M. Buck, K. Houglum, and M. Chojkier Activation of HSC by TGF-alpha and collagen type I is mediated by oxidative stress through c-myb expression J. Clin. Invest. 96 1995 2461 2468
    • (1995) J. Clin. Invest. , vol.96 , pp. 2461-2468
    • Lee, K.S.1    Buck, M.2    Houglum, K.3    Chojkier, M.4
  • 35
    • 0018841962 scopus 로고
    • Carcinogenecity, teratogenecity and mutagenecity of arsenic
    • A. Leonard, and R.R. Lauwerys Carcinogenecity, teratogenecity and mutagenecity of arsenic Mutat. Res 75 1 1980 49 62
    • (1980) Mutat. Res , vol.75 , Issue.1 , pp. 49-62
    • Leonard, A.1    Lauwerys, R.R.2
  • 36
    • 0025102226 scopus 로고
    • Determination of carbonyl content in oxidatively modified proteins
    • R. Levine, D. Garland, and C.N. Oliver Determination of carbonyl content in oxidatively modified proteins Methods Enzymol. 186 1990 464 478
    • (1990) Methods Enzymol. , vol.186 , pp. 464-478
    • Levine, R.1    Garland, D.2    Oliver, C.N.3
  • 37
    • 0019946708 scopus 로고
    • Autoradiographic studies on the distribution of arsenic in mice and hamster administered 74As-arsenite or arsenate
    • A. Lindgren, M. Vahter, and L. Dencker Autoradiographic studies on the distribution of arsenic in mice and hamster administered 74As-arsenite or arsenate Acta Pharmacol. Toxicol. 51 1982 253 265
    • (1982) Acta Pharmacol. Toxicol. , vol.51 , pp. 253-265
    • Lindgren, A.1    Vahter, M.2    Dencker, L.3
  • 39
    • 0021252057 scopus 로고
    • The effect of methyl transferase inhibition on the metabolism of (74As) arsenite in mice and rabbits
    • E. Marafante, and M. Vahter The effect of methyl transferase inhibition on the metabolism of (74As) arsenite in mice and rabbits Chem. Biol. Interact. 50 1984 49 57
    • (1984) Chem. Biol. Interact. , vol.50 , pp. 49-57
    • Marafante, E.1    Vahter, M.2
  • 40
    • 0023357951 scopus 로고
    • Effects of low dietary intake of methionine, choline or proteins on the biotransformation of arsenite in the rabbit
    • E. Marafante, and M. Vahter Effects of low dietary intake of methionine, choline or proteins on the biotransformation of arsenite in the rabbit Toxicol. Lett. 37 1987 41 46
    • (1987) Toxicol. Lett. , vol.37 , pp. 41-46
    • Marafante, E.1    Vahter, M.2
  • 41
    • 0024516970 scopus 로고
    • Differential effects of IL-1 alpha, TNF-alpha, TGF-beta1 on cell proliferation and collagen formation by cultured fat storing cells
    • M. Matsuoka, N.T. Pham, and H. Tsukamoto Differential effects of IL-1 alpha, TNF-alpha, TGF-beta1 on cell proliferation and collagen formation by cultured fat storing cells Liver 9 1989 71 78
    • (1989) Liver , vol.9 , pp. 71-78
    • Matsuoka, M.1    Pham, N.T.2    Tsukamoto, H.3
  • 42
    • 0024587645 scopus 로고
    • Increased tumor necrosis factor production by monocytes in alcoholic hepatitis
    • C.J. McClain, and D.A. Cohen Increased tumor necrosis factor production by monocytes in alcoholic hepatitis Hepatology 9 3 1989 349 351
    • (1989) Hepatology , vol.9 , Issue.3 , pp. 349-351
    • McClain, C.J.1    Cohen, D.A.2
  • 43
    • 0025171323 scopus 로고
    • Arsenic and noncirrhotic portal hypertension-A report of eight cases
    • F. Nevens, S.W. Van, R. Sciot, V. Desmet, and I.D. Groote Arsenic and noncirrhotic portal hypertension-A report of eight cases J. Hepatol. 11 1990 80 85
    • (1990) J. Hepatol. , vol.11 , pp. 80-85
    • Nevens, F.1    Van, S.W.2    Sciot, R.3    Desmet, V.4    Groote, I.D.5
  • 44
    • 0029125812 scopus 로고
    • Sequential acetaldehyde production, lipid peroxidation and fibrogenesis in a micropig model of alcohol induced liver disease
    • O. Niemela, S. Parkkila, H.S. Yla, J. Villaneuva, B. Ruetner, and C.H. Halsted Sequential acetaldehyde production, lipid peroxidation and fibrogenesis in a micropig model of alcohol induced liver disease Hepatology 22 1995 1208 1214
    • (1995) Hepatology , vol.22 , pp. 1208-1214
    • Niemela, O.1    Parkkila, S.2    Yla, H.S.3    Villaneuva, J.4    Ruetner, B.5    Halsted, C.H.6
  • 45
    • 0033134774 scopus 로고    scopus 로고
    • Hepatic lipid peroxidation in hereditary hemochromatosis and alcoholic liver injury
    • O. Niemela, S. Parkkila, and R.S. Britton Hepatic lipid peroxidation in hereditary hemochromatosis and alcoholic liver injury J. Lab. Clin. Med. 133 1999 451
    • (1999) J. Lab. Clin. Med. , vol.133 , pp. 451
    • Niemela, O.1    Parkkila, S.2    Britton, R.S.3
  • 46
    • 0028351241 scopus 로고
    • Glutathione plays different roles in the induction of the cytotoxic effects of inorganic and organic arsenic compounds in cultured BALB/c 3T3 cells
    • T. Ochi, T. Kaise, and Y. Oyabhta Glutathione plays different roles in the induction of the cytotoxic effects of inorganic and organic arsenic compounds in cultured BALB/c 3T3 cells Experientia 50 2 1994 115 120
    • (1994) Experientia , vol.50 , Issue.2 , pp. 115-120
    • Ochi, T.1    Kaise, T.2    Oyabhta, Y.3
  • 47
    • 0014108436 scopus 로고
    • Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase
    • D.E. Paglia, and W.N. Valentine Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase J. Lab. Clin. Med. 70 1967 158 169
    • (1967) J. Lab. Clin. Med. , vol.70 , pp. 158-169
    • Paglia, D.E.1    Valentine, W.N.2
  • 48
  • 49
    • 0030585347 scopus 로고    scopus 로고
    • Induction of procollagen type I gene expression and synthesis in human hepatic stellate cells by 4-hydroxy 2, 3-nonenal and other 4-hydroxy-2, 3-alkenals is related to their molecular structure
    • M. Parola, M. Pinzani, and A. Casini Induction of procollagen type I gene expression and synthesis in human hepatic stellate cells by 4-hydroxy 2, 3-nonenal and other 4-hydroxy-2, 3-alkenals is related to their molecular structure Biochem. Biophys. Res. Commun. 222 1996 261
    • (1996) Biochem. Biophys. Res. Commun. , vol.222 , pp. 261
    • Parola, M.1    Pinzani, M.2    Casini, A.3
  • 50
    • 0032937658 scopus 로고    scopus 로고
    • Treatment with glutathione precursor decreases cytokine activity
    • L.R. Pena, D.B. Hill, and C.J. McClain Treatment with glutathione precursor decreases cytokine activity J. Parenter. Enteral Nutr. 23 1 1999 1 6
    • (1999) J. Parenter. Enteral Nutr. , vol.23 , Issue.1 , pp. 1-6
    • Pena, L.R.1    Hill, D.B.2    McClain, C.J.3
  • 51
  • 52
    • 0023440684 scopus 로고
    • The role of lipid peroxidation in liver damage
    • G. Poli, E. Albano, and M.U. Dianzani The role of lipid peroxidation in liver damage Chem. Phys. Lipids 45 1987 117 142
    • (1987) Chem. Phys. Lipids , vol.45 , pp. 117-142
    • Poli, G.1    Albano, E.2    Dianzani, M.U.3
  • 53
    • 0036142543 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha, but not Fas, mediates hepatocellular apoptosis in the murine ischemic liver
    • H. Rudiger, and P.A. Clavien Tumor necrosis factor alpha, but not Fas, mediates hepatocellular apoptosis in the murine ischemic liver Gastroenterology 122 2002 202 210
    • (2002) Gastroenterology , vol.122 , pp. 202-210
    • Rudiger, H.1    Clavien, P.A.2
  • 55
    • 0032965134 scopus 로고    scopus 로고
    • Hepatic fibrogenesis using chronic arsenic ingestion: Studies in a murine model
    • S.K. Sarin, G. Sharma, S. Banerjee, R. Sathayat, and V. Malhotra Hepatic fibrogenesis using chronic arsenic ingestion: studies in a murine model Ind. J. Exp. Biol. 37 1999 147 151
    • (1999) Ind. J. Exp. Biol. , vol.37 , pp. 147-151
    • Sarin, S.K.1    Sharma, G.2    Banerjee, S.3    Sathayat, R.4    Malhotra, V.5
  • 57
    • 0025088859 scopus 로고
    • Oxidant injury to hepatic mitochondrial lipids in rats with dietary copper overload. Modification by vitamin e deficiency
    • R.J. Sokol, M. Devereaux, G.W. Mierau, K.M. Hambidge, and R.H. Shikes Oxidant injury to hepatic mitochondrial lipids in rats with dietary copper overload. Modification by vitamin E deficiency Gastroenterology 99 4 1990 (Oct) 1061 1071
    • (1990) Gastroenterology , vol.99 , Issue.4 , pp. 1061-1071
    • Sokol, R.J.1    Devereaux, M.2    Mierau, G.W.3    Hambidge, K.M.4    Shikes, R.H.5
  • 58
    • 0021359934 scopus 로고
    • The search for a solution to senile cataracts. Proctor lecture
    • A. Spector The search for a solution to senile cataracts. Proctor lecture Invest. Opthalmol. Visual Sci. 25 1984 130 146
    • (1984) Invest. Opthalmol. Visual Sci. , vol.25 , pp. 130-146
    • Spector, A.1
  • 61
    • 24844459981 scopus 로고
    • Effects of sulfhydryl reagents on peroxidation in microsomes
    • H.G. Utley, F. Bernheim, and P. Hochstein Effects of sulfhydryl reagents on peroxidation in microsomes Arch. Biochem. Biophys. 118 1967 29
    • (1967) Arch. Biochem. Biophys. , vol.118 , pp. 29
    • Utley, H.G.1    Bernheim, F.2    Hochstein, P.3
  • 62
    • 0031912463 scopus 로고    scopus 로고
    • Ethanol induced changes of intracellular thiol compartmentation and protein redox status in the liver: Effect of tauroursodeoxycholate
    • G. Vendemiale, I. Grattagliano, A. Signorile, and E. Altomere Ethanol induced changes of intracellular thiol compartmentation and protein redox status in the liver: effect of tauroursodeoxycholate J. Hepatol. 28 1 1998 46 53
    • (1998) J. Hepatol. , vol.28 , Issue.1 , pp. 46-53
    • Vendemiale, G.1    Grattagliano, I.2    Signorile, A.3    Altomere, E.4
  • 63
    • 0006229140 scopus 로고    scopus 로고
    • Hepatic metabolism of xenobiotics in humans
    • D. Zakim T.D. Boyer 4th ed. Saunders
    • D.A. Vessey Hepatic metabolism of xenobiotics in humans D. Zakim T.D. Boyer Hepatology-A text book of liver disease 4th ed. 2002 Saunders
    • (2002) Hepatology-A Text Book of Liver Disease
    • Vessey, D.A.1
  • 64
    • 0001166643 scopus 로고    scopus 로고
    • The carcinogenecity of arsenic
    • L.W. Chang
    • Z. Wang, and T.G. Rossman The carcinogenecity of arsenic L.W. Chang Toxicology of Metals 1996 219 227
    • (1996) Toxicology of Metals , pp. 219-227
    • Wang, Z.1    Rossman, T.G.2
  • 65
    • 0025054976 scopus 로고
    • Ito cell gene expression and collagen regulation
    • F.R. Weiner, M.A. Giambrone, and MJ. Czaja Ito cell gene expression and collagen regulation Hepatology 11 1990 111 117
    • (1990) Hepatology , vol.11 , pp. 111-117
    • Weiner, F.R.1    Giambrone, M.A.2    Czaja, M.J.3
  • 67
  • 68
    • 0025274032 scopus 로고
    • Induction of DNA damage by dimethylarsine, a metabolite of inorganic arsenic, is for the major part likely due to its peroxyl radical
    • K. Yamanaka, M. Hoshino, M. Okamoto, R. Sawamura, A. Hasegawa, and S. Okuda Induction of DNA damage by dimethylarsine, a metabolite of inorganic arsenic, is for the major part likely due to its peroxyl radical Biochem. Biophys. Res. Commun. 168 1990 58 64
    • (1990) Biochem. Biophys. Res. Commun. , vol.168 , pp. 58-64
    • Yamanaka, K.1    Hoshino, M.2    Okamoto, M.3    Sawamura, R.4    Hasegawa, A.5    Okuda, S.6
  • 69
    • 0025995994 scopus 로고
    • Ethanol induced changes in hepatic free radical defense mechanisms and fatty acid composition in the miniature pig
    • C.S. Zindenberg, K.L. Olin, and J. Villarweva Ethanol induced changes in hepatic free radical defense mechanisms and fatty acid composition in the miniature pig Hepatology 13 1991 1185
    • (1991) Hepatology , vol.13 , pp. 1185
    • Zindenberg, C.S.1    Olin, K.L.2    Villarweva, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.