메뉴 건너뛰기




Volumn 5, Issue 9, 2010, Pages 1-11

Phyllanthus spp. induces selective growth inhibition of PC-3 and mewo human cancer cells through modulation of cell cycle and induction of apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 7; DOXORUBICIN; ELLAGITANNIN; FLAVONOID; FLUOROURACIL; LACTATE DEHYDROGENASE; METHANOL; PHYLLANTHUS AMARUS EXTRACT; PHYLLANTHUS NIRURI EXTRACT; PHYLLANTHUS URINARIA EXTRACT; PHYLLANTHUS WATSONII EXTRACT; PLANT EXTRACT; TANNIN; UNCLASSIFIED DRUG; WATER; GROWTH INHIBITOR;

EID: 77958556051     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012644     Document Type: Article
Times cited : (80)

References (47)
  • 1
    • 33845973448 scopus 로고    scopus 로고
    • Cranberry photochemical extracts induce cell cycle arrest and apoptotsis in human MCF-7 breast cancer cells
    • Sun J, Liu RH (2005) Cranberry photochemical extracts induce cell cycle arrest and apoptotsis in human MCF-7 breast cancer cells. Cancer Lett 241: 124-134.
    • (2005) Cancer Lett , vol.241 , pp. 124-134
    • Sun, J.1    Liu, R.H.2
  • 3
    • 67650410937 scopus 로고    scopus 로고
    • American Cancer Society, Atlanta: ACS
    • American Cancer Society (2009) Cancer Facts & Figures 2009. Atlanta: ACS. Pp 19-20.
    • (2009) Cancer Facts & Figures 2009 , pp. 19-20
  • 4
    • 77958589039 scopus 로고    scopus 로고
    • Skin cancer - UK incidence statistic
    • Cancer Research UK, Available, Accessed 2010 Apr 1
    • Cancer Research UK (2010) Skin cancer - UK incidence statistic. Cancer Research UK. Available: http://info.cancerresearchuk.org/cancerstats/types/skin/incidence/. Accessed 2010 Apr 1.
    • (2010) Cancer Research UK
  • 5
    • 65149090153 scopus 로고    scopus 로고
    • Anticancer agents from medicinal plants
    • Shoeb M (2006) Anticancer agents from medicinal plants. Bangledesh J Pharmacol 1: 35-41.
    • (2006) Bangledesh J Pharmacol , vol.1 , pp. 35-41
    • Shoeb, M.1
  • 6
    • 77955684325 scopus 로고    scopus 로고
    • Andrographolide: A new plant-derived antineoplastic entity on Horizon
    • In press
    • Varma A, Padh H, Shrivastava N (2009) Andrographolide: A new plant-derived antineoplastic entity on Horizon. eCAM, In press.
    • (2009) ECAM
    • Varma, A.1    Padh, H.2    Shrivastava, N.3
  • 7
    • 23044490704 scopus 로고    scopus 로고
    • Plants as a source of anti-cancer agents
    • Cragg GM, Newman DJ (2005) Plants as a source of anti-cancer agents. J Ethnopharmacol 100: 72-79.
    • (2005) J Ethnopharmacol , vol.100 , pp. 72-79
    • Cragg, G.M.1    Newman, D.J.2
  • 9
    • 30744444426 scopus 로고
    • Hepatitis B virus and primary hepatocellular carcinoma: Treatment of HBV carriers with Phyllanthus amarus
    • Blumberg BS, Millman I, Venkeatswaran PS, Thyagarajan SP (1990) Hepatitis B virus and primary hepatocellular carcinoma: Treatment of HBV carriers with Phyllanthus amarus. Vaccine 8: S86-S92.
    • (1990) Vaccine , vol.8
    • Blumberg, B.S.1    Millman, I.2    Venkeatswaran, P.S.3    Thyagarajan, S.P.4
  • 10
    • 2642611443 scopus 로고    scopus 로고
    • Effects of an extracts from Phyllanthus niruri on hepatitis B and woodchuck hepatitis virus: In vitro and in vivo studies
    • Venkateswaran PS, Millman I, Blumberg BS (1997) Effects of an extracts from Phyllanthus niruri on hepatitis B and woodchuck hepatitis virus: in vitro and in vivo studies. Proc Natl Acad Sci 84(1): 274-278.
    • (1997) Proc Natl Acad Sci , vol.84 , Issue.1 , pp. 274-278
    • Venkateswaran, P.S.1    Millman, I.2    Blumberg, B.S.3
  • 11
    • 0030456226 scopus 로고    scopus 로고
    • Phyllanthus amarus down-regulates hepatitis B virus mRNA transcription and translation
    • Lee CD, Ott M, Thygarajan SP, Shfritz DA, Burk RD, et al. (1996) Phyllanthus amarus down-regulates hepatitis B virus mRNA transcription and translation. Eur J Clin Invest 26: 1069-1076.
    • (1996) Eur J Clin Invest , vol.26 , pp. 1069-1076
    • Lee, C.D.1    Ott, M.2    Thygarajan, S.P.3    Shfritz, D.A.4    Burk, R.D.5
  • 12
    • 0030780101 scopus 로고    scopus 로고
    • Phyllanthus amarus suppress hepatitis B virus interrupting interactions between HBV enhancer I and cellular transcription factors
    • Ott M, Thyarajan SP, Gupta S (1997) Phyllanthus amarus suppress hepatitis B virus interrupting interactions between HBV enhancer I and cellular transcription factors. Eur J Clin Invest 11: 908-915.
    • (1997) Eur J Clin Invest , vol.11 , pp. 908-915
    • Ott, M.1    Thyarajan, S.P.2    Gupta, S.3
  • 13
    • 33646388016 scopus 로고    scopus 로고
    • Antimicrobial potentially of Phyllanthus amarus against drug resistant pathogens
    • Mazumder A, Mahato A, Mazumder R (2006) Antimicrobial potentially of Phyllanthus amarus against drug resistant pathogens. Nat Prod Res 20: 323-326.
    • (2006) Nat Prod Res , vol.20 , pp. 323-326
    • Mazumder, A.1    Mahato, A.2    Mazumder, R.3
  • 14
    • 19444369324 scopus 로고    scopus 로고
    • Antibacterial screening of some Peruvian medicinal plants used in Calleria District
    • Kloucek P, Polesny Z, Svobodova B, Vlkova E, Kokoska L (2005) Antibacterial screening of some Peruvian medicinal plants used in Calleria District. J Ethnopharmacol 99: 309-312.
    • (2005) J Ethnopharmacol , vol.99 , pp. 309-312
    • Kloucek, P.1    Polesny, Z.2    Svobodova, B.3    Vlkova, E.4    Kokoska, L.5
  • 15
    • 0031061012 scopus 로고    scopus 로고
    • Mechanism of protective action of Phyllanthus niruri L. against injuries of liver cells
    • Zhou S, Xu C, Zhou N, Huang Y, Huang L, et al. (1997) Mechanism of protective action of Phyllanthus niruri L. against injuries of liver cells. Zhongguo Zhong Yao Za Zhi 22(2): 109-111.
    • (1997) Zhongguo Zhong Yao Za Zhi , vol.22 , Issue.2 , pp. 109-111
    • Zhou, S.1    Xu, C.2    Zhou, N.3    Huang, Y.4    Huang, L.5
  • 17
    • 0033026704 scopus 로고    scopus 로고
    • Effects of Emblica officinalis, Phyllanthus amarus and Picrorrhiza Kurroa on N-nitrosodiethylamine induced hepatocarcinogn-esis
    • Jeena KJ, Joy KL, Kuttan R (1999) Effects of Emblica officinalis, Phyllanthus amarus and Picrorrhiza Kurroa on N-nitrosodiethylamine induced hepatocarcinogn-esis. Cancer Lett 136: 11-16.
    • (1999) Cancer Lett , vol.136 , pp. 11-16
    • Jeena, K.J.1    Joy, K.L.2    Kuttan, R.3
  • 18
    • 0029619040 scopus 로고    scopus 로고
    • Comparative hepatoprotective activity of three Phyllanthus species, P. urinaria, P. niruri and P. simplex, on carbon tetrachloride induced liver injury in the rat
    • Prakash A, Satyan KS, Wahi SP, Sing RP (2006) Comparative hepatoprotective activity of three Phyllanthus species, P. urinaria, P. niruri and P. simplex, on carbon tetrachloride induced liver injury in the rat. Phytotherapy Res 9(8): 594-596.
    • (2006) Phytotherapy Res , vol.9 , Issue.8 , pp. 594-596
    • Prakash, A.1    Satyan, K.S.2    Wahi, S.P.3    Sing, R.P.4
  • 19
    • 33846621470 scopus 로고    scopus 로고
    • Hepatoprotection of Phyllanthus maderaspatensis against experimentally induced liver injury in rats
    • Asha VV, Sheeba MS, Suresh V, Wills PJ (2007) Hepatoprotection of Phyllanthus maderaspatensis against experimentally induced liver injury in rats. Fitoterapia 78(2): 134-141.
    • (2007) Fitoterapia , vol.78 , Issue.2 , pp. 134-141
    • Asha, V.V.1    Sheeba, M.S.2    Suresh, V.3    Wills, P.J.4
  • 20
    • 0033797891 scopus 로고    scopus 로고
    • Phyllanthus amarus extract administration increases the life span of rats with hepatocellular carcinoma
    • Rajeshkumar NV, Kuttan R (2000) Phyllanthus amarus extract administration increases the life span of rats with hepatocellular carcinoma. J Ethnopharmacol 73: 215-219.
    • (2000) J Ethnopharmacol , vol.73 , pp. 215-219
    • Rajeshkumar, N.V.1    Kuttan, R.2
  • 21
    • 27644594947 scopus 로고    scopus 로고
    • Antihyperglcemic effect and antioxidant potential of Phyllanthus niruri in streptozotocin induced diabetic rats
    • Mazunder UK, Gupta M, Rajeshwar Y (2005) Antihyperglcemic effect and antioxidant potential of Phyllanthus niruri in streptozotocin induced diabetic rats. Eur Bull Drug Res 13: 15-23.
    • (2005) Eur Bull Drug Res , vol.13 , pp. 15-23
    • Mazunder, U.K.1    Gupta, M.2    Rajeshwar, Y.3
  • 22
    • 0036332106 scopus 로고    scopus 로고
    • Hypoglycemic effect of methanol extract of Phyllanthus amarus Schum and Thonn on alloxan induced diabetes mellitus in rats and its relation with antioxidant potential
    • Raphael KR, Ajith TA, Joseph S, Kuttan R (2002) Hypoglycemic effect of methanol extract of Phyllanthus amarus Schum and Thonn on alloxan induced diabetes mellitus in rats and its relation with antioxidant potential. Ind J Exp Biol 40: 905-909.
    • (2002) Ind J Exp Biol , vol.40 , pp. 905-909
    • Raphael, K.R.1    Ajith, T.A.2    Joseph, S.3    Kuttan, R.4
  • 23
    • 1542322900 scopus 로고    scopus 로고
    • Why target apoptosis in cancer treatment?
    • Kasibhatla S, Tseng B (2003) Why target apoptosis in cancer treatment? Mol Cancer Ther 2: 573-80.
    • (2003) Mol Cancer Ther , vol.2 , pp. 573-580
    • Kasibhatla, S.1    Tseng, B.2
  • 24
    • 9244251125 scopus 로고    scopus 로고
    • Cell-cycle checkpoints and cancer
    • Kastan MB, Bartek J (2004) Cell-cycle checkpoints and cancer. Nature 432: 316-23.
    • (2004) Nature , vol.432 , pp. 316-323
    • Kastan, M.B.1    Bartek, J.2
  • 26
    • 33947726393 scopus 로고    scopus 로고
    • Anticancer effects of gallic acid isolated from Indonesian herbal medicine, Phaleria macrocarpa (Scheff.) Boerl, on human cancer cell lines
    • Faried A, Kurnia D, Faried LS, Usman N, Miyazaki T, et al. (2007) Anticancer effects of gallic acid isolated from Indonesian herbal medicine, Phaleria macrocarpa (Scheff.) Boerl, on human cancer cell lines. Int J Oncol 30: 605-613.
    • (2007) Int J Oncol , vol.30 , pp. 605-613
    • Faried, A.1    Kurnia, D.2    Faried, L.S.3    Usman, N.4    Miyazaki, T.5
  • 27
    • 24744434694 scopus 로고    scopus 로고
    • A phenolic compound, 5-caffeolquinic acid (chlorogenic acid) is a new type and strong matrix metalloproteinase-9 inhibitor: Isolation and identification from methanol extract of Euonymus alatus
    • Jin UH, Lee JY, Kang SK, Park WH, Kim JH, et al. (2005) A phenolic compound, 5-caffeolquinic acid (chlorogenic acid) is a new type and strong matrix metalloproteinase-9 inhibitor: isolation and identification from methanol extract of Euonymus alatus. Life Sci 77(22): 2760-2769.
    • (2005) Life Sci , vol.77 , Issue.22 , pp. 2760-2769
    • Jin, U.H.1    Lee, J.Y.2    Kang, S.K.3    Park, W.H.4    Kim, J.H.5
  • 28
    • 2342591291 scopus 로고    scopus 로고
    • Phyllanthus urinaria induces the Fas receptor/ligand expression and ceramide-mediated apoptotsis in HL-60 cells
    • Huang ST, Yang RC, Chen MY, Pang JHS (2004) Phyllanthus urinaria induces the Fas receptor/ligand expression and ceramide-mediated apoptotsis in HL-60 cells. Life Sci 75: 339-351.
    • (2004) Life Sci , vol.75 , pp. 339-351
    • Huang, S.T.1    Yang, R.C.2    Chen, M.Y.3    Pang, J.H.S.4
  • 29
    • 33644830944 scopus 로고    scopus 로고
    • Targeting the cell cycle: A new approach to cancer therapy
    • Schwartz GK, Shah MA (2005) Targeting the cell cycle: A new approach to cancer therapy. J Clin Oncol 23: 9408-9421.
    • (2005) J Clin Oncol , vol.23 , pp. 9408-9421
    • Schwartz, G.K.1    Shah, M.A.2
  • 30
    • 0034717309 scopus 로고    scopus 로고
    • Rapid destruction of human Cdc25A in response to DNA damage
    • Mailand N, Falck J, Lukas C, Syljuâsen RG, Welcker M, et al. (2000) Rapid destruction of human Cdc25A in response to DNA damage. Science 288(5470): 1425-1429.
    • (2000) Science , vol.288 , Issue.5470 , pp. 1425-1429
    • Mailand, N.1    Falck, J.2    Lukas, C.3    Syljuâsen, R.G.4    Welcker, M.5
  • 31
    • 0034232093 scopus 로고    scopus 로고
    • Human Cdc2A inactivation in response to S phase inhibition and its role in preventing premature mitosis
    • Molinari M, Mercurio C, Dominguez J, Goubin F, Draetta GF (2000) Human Cdc2A inactivation in response to S phase inhibition and its role in preventing premature mitosis. EMBO Reports 1: 71-79.
    • (2000) EMBO Reports , vol.1 , pp. 71-79
    • Molinari, M.1    Mercurio, C.2    Dominguez, J.3    Goubin, F.4    Draetta, G.F.5
  • 32
    • 67049162195 scopus 로고    scopus 로고
    • Erbb2 Suppresses DNA Damage-Induced Checkpoint Activation and UV-Induced Mouse Skin Tumorigenesis
    • Madson JG, Lynch DT, Svoboda J, Ophardt R, Yanagida J, et al. (2009) Erbb2 Suppresses DNA Damage-Induced Checkpoint Activation and UV-Induced Mouse Skin Tumorigenesis. Am J Pathol 174(6): 2357-2366.
    • (2009) Am J Pathol , vol.174 , Issue.6 , pp. 2357-2366
    • Madson, J.G.1    Lynch, D.T.2    Svoboda, J.3    Ophardt, R.4    Yanagida, J.5
  • 33
    • 4344650868 scopus 로고    scopus 로고
    • Telomere-based DNA damage responses: A new approach to melanoma
    • Puri N, Eller MS, Byers HR, Dykstra S, Kubera J, et al. (2004) Telomere-based DNA damage responses: A new approach to melanoma. FASEB J 18: 1373-1381.
    • (2004) FASEB J , vol.18 , pp. 1373-1381
    • Puri, N.1    Eller, M.S.2    Byers, H.R.3    Dykstra, S.4    Kubera, J.5
  • 34
    • 0034662644 scopus 로고    scopus 로고
    • P53 promotes selection for Fasmediated apoptotic resistance
    • Maecker HL, Koumenis C, Giaccia AJ (2000) P53 promotes selection for Fasmediated apoptotic resistance. Cancer Res 60: 4638-4644.
    • (2000) Cancer Res , vol.60 , pp. 4638-4644
    • Maecker, H.L.1    Koumenis, C.2    Giaccia, A.J.3
  • 35
    • 0141482040 scopus 로고    scopus 로고
    • Antisense therapy targeting MDM2 oncogene in prostate cancer: Effects on proliferation apoptosis, multiple gene expression, and chemotherapy
    • Zhang Z, Li M, Agrawal S, Zhang RW (2003) Antisense therapy targeting MDM2 oncogene in prostate cancer: Effects on proliferation apoptosis, multiple gene expression, and chemotherapy. Proc Natl Acad Sci 100(20): 11636-11641.
    • (2003) Proc Natl Acad Sci , vol.100 , Issue.20 , pp. 11636-11641
    • Zhang, Z.1    Li, M.2    Agrawal, S.3    Zhang, R.W.4
  • 36
    • 73649107966 scopus 로고    scopus 로고
    • Tanshinone IIA induces apoptosis and S phase cell cycle arrest in activated rat hepatitc stellate cells
    • Che XH, Park EJ, Zhao YZ, Kim WH, Sohn DW (2009) Tanshinone IIA induces apoptosis and S phase cell cycle arrest in activated rat hepatitc stellate cells. Basic Clin Pharmacol Toxicol 106: 30-37.
    • (2009) Basic Clin Pharmacol Toxicol , vol.106 , pp. 30-37
    • Che, X.H.1    Park, E.J.2    Zhao, Y.Z.3    Kim, W.H.4    Sohn, D.W.5
  • 37
    • 8744253746 scopus 로고    scopus 로고
    • Possible synergistic prostate cancer suppression by anatomically discrete pomegranate fractions
    • Lansky EP, Jiang W, Mo H, Bravo L, Froom P, et al. (2005) Possible synergistic prostate cancer suppression by anatomically discrete pomegranate fractions. Invest New Drugs 23: 11-20.
    • (2005) Invest New Drugs , vol.23 , pp. 11-20
    • Lansky, E.P.1    Jiang, W.2    Mo, H.3    Bravo, L.4    Froom, P.5
  • 38
    • 10344233656 scopus 로고    scopus 로고
    • Epicatechin gallate-induced expression of NAG-1 is associated with growth inhibition and apoptosis in colon cancer cells
    • Baek SJ, Kim JS, Jackson FR, Eling TE, McEntee MF, et al. (2004) Epicatechin gallate-induced expression of NAG-1 is associated with growth inhibition and apoptosis in colon cancer cells. Carcinogenesis 25(12): 2425-2432.
    • (2004) Carcinogenesis , vol.25 , Issue.12 , pp. 2425-2432
    • Baek, S.J.1    Kim, J.S.2    Jackson, F.R.3    Eling, T.E.4    McEntee, M.F.5
  • 39
    • 18144382254 scopus 로고    scopus 로고
    • Ablation of either p21 or Bax prevents p53-dependent apoptosis induced by green tea polyphenol epigallocatechin-3-gallate
    • Hastak K, Agarwal MK, Mukhtar H, Agarwal ML (2005) Ablation of either p21 or Bax prevents p53-dependent apoptosis induced by green tea polyphenol epigallocatechin-3-gallate. FASEB J 19: 789-791.
    • (2005) FASEB J , vol.19 , pp. 789-791
    • Hastak, K.1    Agarwal, M.K.2    Mukhtar, H.3    Agarwal, M.L.4
  • 40
    • 0036785525 scopus 로고    scopus 로고
    • DNA damage induces a novel p53-survivin signalling pathway regulating cell cycle and apoptosis in acute lymphoblastic leukemia cells
    • Zhou MX, Gu LB, Li FZ, Zhu YR, Woods WG, et al. (2002) DNA damage induces a novel p53-survivin signalling pathway regulating cell cycle and apoptosis in acute lymphoblastic leukemia cells. J Pharmacol Exp Therapeut 303(1): 124-131.
    • (2002) J Pharmacol Exp Therapeut , vol.303 , Issue.1 , pp. 124-131
    • Zhou, M.X.1    Gu, L.B.2    Li, F.Z.3    Zhu, Y.R.4    Woods, W.G.5
  • 41
    • 28444467028 scopus 로고    scopus 로고
    • Doxorubicin prevents endoplasmic reticulum stress-induced apoptosis
    • Kim SJ, Park KM, Kim NY, Yeom YI (2006) Doxorubicin prevents endoplasmic reticulum stress-induced apoptosis. Biochem Biophys Res Commun 339: 463-468.
    • (2006) Biochem Biophys Res Commun , vol.339 , pp. 463-468
    • Kim, S.J.1    Park, K.M.2    Kim, N.Y.3    Yeom, Y.I.4
  • 42
    • 0031691804 scopus 로고    scopus 로고
    • Histopathological evaluation of apoptosis in cancer
    • Soini Y, Pääkkö P, Lehto VP (1998) Histopathological evaluation of apoptosis in cancer. Am J Pathol 154(4): 1041-1053.
    • (1998) Am J Pathol , vol.154 , Issue.4 , pp. 1041-1053
    • Soini, Y.1    Pääkkö, P.2    Lehto, V.P.3
  • 44
    • 70349213747 scopus 로고    scopus 로고
    • Gallic acid induces apoptosisi via caspase-3 and mitochondrion-depedent pathways in vitro and suppresses lung xenograft tumor growth in vivo
    • Ji BC, Hsu WH, Yang JS, Hsia TC, Lu CC, et al. (2009) Gallic acid induces apoptosisi via caspase-3 and mitochondrion-depedent pathways in vitro and suppresses lung xenograft tumor growth in vivo. J Agric Food Chem 57(16): 7596-7604.
    • (2009) J Agric Food Chem , vol.57 , Issue.16 , pp. 7596-7604
    • Ji, B.C.1    Hsu, W.H.2    Yang, J.S.3    Hsia, T.C.4    Lu, C.C.5
  • 46
    • 0034949453 scopus 로고    scopus 로고
    • Anticancer drugs induce necrosis of human endothelial cells involving both oncosis and apoptosis
    • Mailloux A, Grenet K, Bruneel A, Bénéteau-Burnat B, Vaubourdolle M, et al. (2001) Anticancer drugs induce necrosis of human endothelial cells involving both oncosis and apoptosis. Eur J Cel Biol 80(6): 442-449.
    • (2001) Eur J Cel Biol , vol.80 , Issue.6 , pp. 442-449
    • Mailloux, A.1    Grenet, K.2    Bruneel, A.3    Bénéteau-Burnat, B.4    Vaubourdolle, M.5
  • 47
    • 0033032641 scopus 로고    scopus 로고
    • S100-Beta, melanoma-inhibiting activity, and lactate dehydrogenase discriminate progressive from nonprogressive American joint committee on cancer stage IV melanoma
    • Deichmann M, Benner A, Bock M, Jäckel A, Uhl K, et al. (1999) S100-Beta, melanoma-inhibiting activity, and lactate dehydrogenase discriminate progressive from nonprogressive American joint committee on cancer stage IV melanoma. J Clin Oncol 17(6): 1891-1896.
    • (1999) J Clin Oncol , vol.17 , Issue.6 , pp. 1891-1896
    • Deichmann, M.1    Benner, A.2    Bock, M.3    Jäckel, A.4    Uhl, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.