TCDD induced pericardial edema and relative Cox-2 expression in medaka (Oryzias Latipes) embryos

Toxicological Sciences

Volumn 118, Issue 1, 2010, Pages 213-223

  Dong, Wu ^a,b   Matsumura, Fumio ^c   Kullman, Seth W ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b HUAIHAI INSTITUTE OF TECHNOLOGY   (China)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

COX 2; Medaka; Pericardial edema; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ARACHIDONIC ACID; AROMATIC HYDROCARBON RECEPTOR; CYCLOOXYGENASE 2; CYTOCHROME P450 1A; MESSENGER RNA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIOTOXICITY; CONTROLLED STUDY; DISEASE SEVERITY; DRUG SELECTIVITY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYOTOXICITY; ENZYME INDUCTION; ENZYME INHIBITION; GENE DELETION; GENE EXPRESSION; HEART DEVELOPMENT; HEART EDEMA; ICOSANOID METABOLISM; INFLAMMATION; MORPHOGENESIS; NONHUMAN; ORYZIAS; PERICARDIAL EDEMA; PERICARDIUM; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN TRANSPORT; TRANSLATION INITIATION;

ANIMALS; ARACHIDONIC ACID; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE SILENCING; NITROBENZENES; ORYZIAS; PERICARDIAL EFFUSION; RNA, MESSENGER; SULFONAMIDES; TERATOGENS; TETRACHLORODIBENZODIOXIN;

ORYZIAS LATIPES; ORYZIINAE;

EID: 77958508831     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq254     Document Type: Article

References (59)

1. Antkiewicz, D. S., Burns, C. G., Carney, S. A., Peterson, R. E., and Heideman, W. (2005). Heart malformation is an early response to TCDD in embryonic zebrafish. Toxicol. Sci. 84, 368-377.
2. Antkiewicz, D. S., Peterson, R. E., and Heideman, W. (2006). Blocking expression of AHR2 and ARNT1 in zebrafish larvae protects against cardiac toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Sci. 94, 175-182.
3. Aragon, A. C., Kopf, P. G., Campen, M. J., Huwe, J. K., and Walker, M. K. (2008). In utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: effects on fetal and adult cardiac gene expression and adult cardiac and renal morphology. Toxicol. Sci. 101, 321-330.
4. Arzuaga, X., Reiterer, G., Majkova, Z., Kilgore, M. W., Toborek, M., and Hennig, B. (2007). PPARalpha ligands reduce PCB-induced endothelial activation: possible interactions in inflammation and atherosclerosis. Cardiovasc. Toxicol. 7, 264-272.
5. Auman, H. J., Coleman, H., Riley, H. E., Olale, F., Tsai, H. J., and Yelon, D. (2007). Functional modulation of cardiac form through regionally confined cell shape changes. PLoS Biol. 5, e53.
6. Auman, H. J., and Yelon, D. (2004). Vertebrate organogenesis: getting the heart into shape. Curr. Biol. 14, R152-R153.
7. Bezdecny, S. A., Karmaus, P., Roth, R. A., and Ganey, P. E. (2007). 2,2',4,4'- Tetrachlorobiphenyl upregulates cyclooxygenase-2 in HL-60 cells via p38 mitogen-activated protein kinase and NF-kappaB. Toxicol. Appl. Pharmacol. 221, 285-294.
8. Bezdecny, S. A., Roth, R. A., and Ganey, P. E. (2005). Effects of 2,2',4,4'-tetrachlorobiphenyl on granulocytic HL-60 cell function and expression of cyclooxygenase-2. Toxicol. Sci. 84, 328-334.
9. Carney, M. W., Erwin, K., Hardman, R., Yuen, B., Volz, D. C., Hinton, D. E., and Kullman, S. W. (2008). Differential developmental toxicity of naphthoic acid isomers in medaka (Oryzias latipes) embryos. Mar. Pollut. Bull. 57, 255-266.
10. Carney, S. A., Chen, J., Burns, C. G., Xiong, K. M., Peterson, R. E., and Heideman, W. (2006a). Aryl hydrocarbon receptor activation produces heartspecific transcriptional and toxic responses in developing zebrafish. Mol. Pharmacol. 70, 549-561.
11. Carney, S. A., Prasch, A. L., Heideman, W., and Peterson, R. E. (2006b). Understanding dioxin developmental toxicity using the zebrafish model. Birth. Defects Res. A. Clin. Mol. Teratol. 76, 7-18.
12. Chang, H., Hanawa, H., Liu, H., Yoshida, T., Hayashi, M., Watanabe, R., Abe, S., Toba, K., Yoshida, K., Elnaggar, R., et al. (2006). Hydrodynamicbased delivery of an interleukin-22-Ig fusion gene ameliorates experimental autoimmune myocarditis in rats. J. Immunol. 177, 3635-3643.
13. Chen, C. M., and Cooper, K. R. (1999). Developmental toxicity and EROD induction in the Japanese medaka (Oryzias latipes) treated with dioxin congeners. Bull. Environ. Contam. Toxicol. 63, 423-429.
14. Degner, S. C., Papoutsis, A. J., Selmin, O., and Romagnolo, D. F. (2009). Targeting of aryl hydrocarbon receptor-mediated activation of cyclooxygenase-2 expression by the indole-3-carbinol metabolite 3,3'-diindolylmethane in breast cancer cells. J. Nutr. 139, 26-32.
15. Dong, B., and Matsumura, F. (2008). Roles of cytosolic phospholipase A2 and Src kinase in the early action of 2,3,7,8-tetrachlorodibenzo-p-dioxin through a nongenomic pathway in MCF10A cells. Mol. Pharmacol. 74, 255-263.
16. Dong, B., and Matsumura, F. (2009). The conversion of rapid TCCD nongenomic signals to persistent inflammatory effects via select protein kinases in MCF10A cells. Mol. Endocrinol. 23, 549-558.
17. Dong, B., Nishimura, N., Vogel, C. F., Tohyama, C., and Matsumura, F. (2010). TCDD-induced cyclooxygenase-2 expression is mediated by the nongenomic pathway in mouse MMDD1 macula densa cells and kidneys. Biochem. Pharmacol. 79, 487-497.
18. Grabher, C., Cliffe, A., Miura, K., Hayflick, J., Pepperkok, R., Rorth, P., and Wittbrodt, J. (2007). Birth and life of tissue macrophages and their migration in embryogenesis and inflammation in medaka. J. Leukoc. Biol. 81, 263-271.
19. Grimes, A. C., Erwin, K. N., Stadt, H. A., Hunter, G. L., Gefroh, H. A., Tsai, H. J., and Kirby, M. L. (2008). PCB126 exposure disrupts zebrafish ventricular and branchial but not early neural crest development. Toxicol. Sci. 106, 193-205.
20. Han, E. H., Kim, J. Y., Kim, H. K., Hwang, Y. P., and Jeong, H. G. (2008). o, p'-DDT induces cyclooxygenase-2 gene expression in murine macrophages: role of AP-1 and CRE promoter elements and PI3-kinase/Akt/MAPK signaling pathways. Toxicol. Appl. Pharmacol. 233, 333-342.
21. He, Q., Harding, P., and LaPointe, M. C. (2010). PKA, Rap1, ERK1/2, and p90RSK mediate PGE2 and EP4 signaling in neonatal ventricular myocytes. Am. J. Physiol. Heart. Circ. Physiol. 298, H136-H143.
22. Hinton, R. B., Jr., Martin, L. J., Tabangin, M. E., Mazwi, M. L., Cripe, L. H., and Benson, D. W. (2007). Hypoplastic left heart syndrome is heritable. J. Am. Coll. Cardiol. 50, 1590-1595.
23. Hornung, M. W., Spitsbergen, J. M., and Peterson, R. E. (1999). 2,3,7,8-Tetrachlorodibenzo-p-dioxin alters cardiovascular and craniofacial development and function in sac fry of rainbow trout (Oncorhynchus mykiss). Toxicol. Sci. 47, 40-51.
24. Huang, C. C., Chen, P. C., Huang, C. W., and Yu, J. (2007). Aristolochic acid induces heart failure in zebrafish embryos that is mediated by inflammation. Toxicol. Sci. 100, 486-494.
25. Ishikawa, T. O., and Herschman, H. R. (2007). Two inducible, functional cyclooxygenase-2 genes are present in the rainbow trout genome. J. Cell. Biochem. 102, 1486-1492.
26. Ivnitski, I., Elmaoued, R., and Walker, M. K. (2001). 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) inhibition of coronary development is preceded by a decrease in myocyte proliferation and an increase in cardiac apoptosis. Teratology 64, 201-212.
27. Iwamatsu, T. (2004). Stages of normal development in the medaka Oryzias latipes. Mech. Dev. 121, 605-618.
28. Jenkins, C. M., Cedars, A., and Gross, R. W. (2009). Eicosanoid signalling pathways in the heart. Cardiovasc. Res. 82, 240-249.
29. Kim, S. H., Kim, Y. H., Shin, K. J., Oh, Y. S., Lee, C. S., Kang, K. O., Ryu, S. H., and Suh, P. G. (2005). 2,2',4,6,6'-Pentachlorobiphenyl-induced apoptosis is limited by cyclooxygenase-2 induction. Toxicol. Sci. 83, 397-404.
30. Kopf, P. G., and Walker, M. K. (2009). Overview of developmental heart defects by dioxins, PCBs, and pesticides. J. Environ. Sci. Health. C. Environ. Carcinog. Ecotoxicol. Rev. 27, 276-285.
31. Kwon, O., Lee, E., Moon, T. C., Jung, H., Lin, C. X., Nam, K. S., Baek, S. H., Min, H. K., and Chang, H. W. (2002). Expression of cyclooxygenase-2 and pro-inflammatory cytokines induced by 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) in human mast cells requires NF-kappa B activation. Biol. Pharm. Bull. 25, 1165-1168.
32. Lam, S. H., Chua, H. L., Gong, Z., Lam, T. J., and Sin, Y. M. (2004). Development and maturation of the immune system in zebrafish, Danio rerio: a gene expression profiling, in situ hybridization and immunological study. Dev. Comp. Immunol. 28, 9-28.
33. Li, W., and Matsumura, F. (2008). Significance of the nongenomic, inflammatory pathway in mediating the toxic action of TCDD to induce rapid and long-term cellular responses in 3T3-L1 adipocytes. Biochemistry 47, 13997-14008.
34. Livak, K. J., and Schmittgen, T. D. (2001). Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 4, 402-408.
35. Loftin, C. D., Tiano, H. F., and Langenbach, R. (2002). Phenotypes of the COX-deficient mice indicate physiological and pathophysiological roles for COX-1 and COX-2. Prostaglandins Other Lipid. Mediat. 68-69, 177-185.
36. Matsumura, F. (2009). The significance of the nongenomic pathway in mediating inflammatory signaling of the dioxin-activated Ah receptor to cause toxic effects. Biochem. Pharmacol. 77, 608-626.
37. Mehta, V., Peterson, R. E., and Heideman, W. (2008). 2,3,7,8-Tetrachlorodibenzo-p-dioxin exposure prevents cardiac valve formation in developing zebrafish. Toxicol. Sci. 104, 303-311.
38. Nishimura, N., Matsumura, F., Vogel, C. F., Nishimura, H., Yonemoto, J., Yoshioka, W., and Tohyama, C. (2008). Critical role of cyclooxygenase-2 activation in pathogenesis of hydronephrosis caused by lactational exposure of mice to dioxin. Toxicol. Appl. Pharmacol. 231, 374-383.
39. Prasch, A. L., Tanguay, R. L., Mehta, V., Heideman, W., and Peterson, R. E. (2006). Identification of zebrafish ARNT1 homologs: 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in the developing zebrafish requires ARNT1. Mol. Pharmacol. 69, 776-787.
40. Prasch, A. L., Teraoka, H., Carney, S. A., Dong, W., Hiraga, T., Stegeman, J. J., Heideman, W., and Peterson, R. E. (2003). Aryl hydrocarbon receptor 2 mediates 2,3,7,8-tetrachlorodibenzo-p-dioxin developmental toxicity in zebrafish. Toxicol. Sci. 76, 138-150.
41. Puga, A., Hoffer, A., Zhou, S., Bohm, J. M., Leikauf, G. D., and Shertzer, H. G. (1997). Sustained increase in intracellular free calcium and activation of cyclooxygenase-2 expression in mouse hepatoma cells treated with dioxin. Biochem. Pharmacol. 54, 1287-1296.
42. Scherz, P. J., Huisken, J., Sahai-Hernandez, P., and Stainier, D. Y. (2008). High-speed imaging of developing heart valves reveals interplay of morphogenesis and function. Development 135, 1179-1187.
43. Sciullo, E. M., Dong, B., Vogel, C. F., and Matsumura, F. (2009). Characterization of the pattern of the nongenomic signaling pathway through which TCDD-induces early inflammatory responses in U937 human macrophages. Chemosphere 74, 1531-1537.
44. Sedmera, D., Hu, N., Weiss, K. M., Keller, B. B., Denslow, S., and Thompson, R. P. (2002). Cellular changes in experimental left heart hypoplasia. Anat. Rec. 267, 137-145.
45. Sirois, J., and Richards, J. S. (1993). Transcriptional regulation of the rat prostaglandin endoperoxide synthase 2 gene in granulosa cells. Evidence for the role of a cis-acting C/EBP beta promoterelement. J. Biol. Chem. 268, 21931-21938.
46. Smith, W. L., DeWitt, D. L., and Garavito, R. M. (2000). Cyclooxygenases: structural, cellular, and molecular biology. Annu. Rev. Biochem. 69, 145-182.
47. Streicher, J. M., and Wang, Y. (2008). The role of COX-2 in heart pathology. Cardiovasc. Hematol. Agents Med. Chem. 6, 69-79.
48. Suzuki, J., Ogawa, M., Futamatsu, H., Kosuge, H., Tanaka, H., and Isobe, M. (2006). A cyclooxygenase-2 inhibitor alters Th1/Th2 cytokine balance and suppresses autoimmune myocarditis in rats. J. Mol. Cell. Cardiol. 40, 688-695.
49. Taneda, Y., Konno, S., Makino, S., Morioka, M., Fukuda, K., Imai, Y., Kudo, A., and Kawakami, A. (2010). Epigenetic control of cardiomyocyte production in response toa stress duringthe medaka heart development. Dev.Biol. 340,30-40.
50. Teraoka, H., Kubota, A., Dong, W., Kawai, Y., Yamazaki, K., Mori, C., Harada, Y., Peterson, R. E., and Hiraga, T. (2009). Role of the cyclooxygenase 2-thromboxane pathway in 2,3,7,8-tetrachlorodibenzop-dioxin-induced decrease in mesencephalic vein blood flow in the zebrafish embryo. Toxicol. Appl. Pharmacol. 234, 33-40.
51. Teraoka, H., Kubota, A., Kawai, Y., and Hiraga, T. (2008). Prostanoid signaling mediates circulation failure caused by TCDD in developing zebrafish. In Interdisciplinary Studies on Environmental Chemistry-Biological Responses to Chemical Pollutants (Y. Murakami, K. Nakayama, S. -I. Kitamura, H. Iwata and S. Tanabe, Eds.), pp. 61-80. TERRAPUB, Tokyo, Japan.
52. Vane, J. R., Bakhle, Y. S., and Botting, R. M. (1998). Cyclooxygenases 1 and 2. Annu. Rev. Pharmacol. Toxicol. 38, 97-120.
53. Vogel, C. F., Sciullo, E., and Matsumura, F. (2004). Activation of inflammatory mediators and potential role of ah-receptor ligands in foam cell formation. Cardiovasc. Toxicol. 4, 363-373.
54. Volz, D. C., Bencic, D. C., Hinton, D. E., Law, J. M., and Kullman, S. W. (2005). 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces organ-specific differential gene expression in Japanese medaka (Oryzias latipes). Toxicol. Sci. 85, 572-584.
55. Walker, M. K., and Catron, T. F. (2000). Characterization of cardiotoxicity induced by 2,3,7, 8-tetrachlorodibenzo-p-dioxin and related chemicals during early chick embryo development. Toxicol. Appl. Pharmacol. 167, 210-221.
56. Wong, P. S., Vogel, C. F., Kokosinski, K., and Matsumura, F. (2010). Aryl hydrocarbon receptor activation in NCI-H441 cells and C57BL/6 mice: possible mechanisms for lung dysfunction. Am. J. Respir. Cell. Mol. Biol. 42, 210-217.
57. Yang, F., and Bleich, D. (2004). Transcriptional regulation of cyclooxygenase-2 gene in pancreatic beta-cells. J. Biol. Chem. 279, 35403-35411.
58. Zidar, N., Dolenc-Strazar, Z., Jeruc, J., Jerse, M., Balazic, J., Gartner, U., Jermol, U., Zupanc, T., and Stajer, D. (2007). Expression of cyclooxygenase-1 and cyclooxygenase-2 in the normal human heart and in myocardial infarction. Cardiovasc. Pathol. 16, 300-304.
59. Zidar, N., Odar, K., Glavac, D., Jerse, M., Zupanc, T., and Stajer, D. (2008). Cyclooxygenase in normal human tissues-is COX-1 really a constitutive isoform, and COX-2 an inducible isoform? J. Cell. Mol. Med. 13, 3753-3763.