2,2′,4,4′-Tetrachlorobiphenyl upregulates cyclooxygenase-2 in HL-60 cells via p38 mitogen-activated protein kinase and NF-κB

Toxicology and Applied Pharmacology

Volumn 221, Issue 3, 2007, Pages 285-294

  Bezdecny, Steven A ^a   Karmaus, Peer ^a   Roth, Robert A ^a   Ganey, Patricia E ^a  

^a National Food Safety and Toxicology Center   (United States)

Author keywords

Cyclooxygenase 2; HL 60; NF B; p38; Polychlorinated biphenyl

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2,2',4,4' TETRACHLOROBIPHENYL; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 HYDROXY 2,2,6,6 TETRAMETHYLPIPERIDIN 1 OXYL; ARACHIDONIC ACID; BROMOENOL LACTONE; CYCLOOXYGENASE 2; DACTINOMYCIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PHOSPHOLIPASE A2; PIPERIDINE DERIVATIVE; POLYCHLORINATED BIPHENYL DERIVATIVE; SCAVENGER; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE; UNCLASSIFIED DRUG; 2,4,2',4'-TETRACHLOROBIPHENYL; ENZYME INHIBITOR; POLYCHLORINATED BIPHENYL;

ARTICLE; CELL STRAIN HL 60; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; EXPOSURE; GENE EXPRESSION REGULATION; GENE INDUCTION; HUMAN; HUMAN CELL; NEUTROPHIL; SIGNAL TRANSDUCTION; UPREGULATION; ANALYSIS OF VARIANCE; CELL LINE; DRUG EFFECT; ENZYMOLOGY; GENETICS; GRANULOCYTE PRECURSOR; METABOLISM; NONPARAMETRIC TEST; POLLUTANT; TRANSACTIVATION;

ANALYSIS OF VARIANCE; ARACHIDONIC ACID; CELL LINE; CYCLOOXYGENASE 2; ENVIRONMENTAL POLLUTANTS; ENZYME INHIBITORS; GRANULOCYTE PRECURSOR CELLS; HUMANS; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; POLYCHLORINATED BIPHENYLS; RNA, MESSENGER; SIGNAL TRANSDUCTION; STATISTICS, NONPARAMETRIC; SUPEROXIDES; TRANS-ACTIVATION (GENETICS); UP-REGULATION;

EID: 34249780822     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.03.019     Document Type: Article

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