o,p′-DDT induces cyclooxygenase-2 gene expression in murine macrophages: Role of AP-1 and CRE promoter elements and PI3-kinase/Akt/MAPK signaling pathways

Toxicology and Applied Pharmacology

Volumn 233, Issue 2, 2008, Pages 333-342

  Han, Eun Hee ^a   Kim, Ji Young ^a   Kim, Hyung Kyun ^a   Hwang, Yong Pil ^a   Jeong, Hye Gwang ^a  

^a Chosun University   (South Korea)

Author keywords

AP 1; COX 2; CRE; Mitogen activated protein kinases; o,p DDT

Indexed keywords

BETA ACTIN; CHLORPHENOTANE; CYCLOOXYGENASE 2; DNA AFFINITY PROTEIN BINDING ASSAY; ENDOCRINE DISRUPTOR; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN E2; PROTEIN KINASE B; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; 1,1,1 TRICHLORO 2 (2 CHLOROPHENYL) 2 (4 CHLOROPHENYL)ETHANE; CARCINOGEN; CREB1 PROTEIN, MOUSE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA BINDING PROTEIN; INSECTICIDE; O,P'-DDT;

ANIMAL CELL; ARTICLE; ASSAY; BINDING SITE; CARCINOGENESIS; CARCINOGENICITY; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; ENZYME ACTIVATION; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE INDUCTION; GENETIC TRANSFECTION; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; PROMOTER REGION; PROSTAGLANDIN SYNTHESIS; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL LINE; DOSE RESPONSE; DRUG EFFECT; GENE EXPRESSION REGULATION; METABOLISM;

MURINAE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CARCINOGENS; CELL LINE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLOOXYGENASE 2; DDT; DINOPROSTONE; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INSECTICIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; TRANSFECTION;

EID: 56049125234     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2008.09.003     Document Type: Article

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