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Volumn 27, Issue 20, 2008, Pages 2736-2745

Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity

Author keywords

Apoptosis; Cdh1; Cdk5; Cyclin B1; Neurons

Indexed keywords

CYCLIN B1; CYCLIN DEPENDENT KINASE 5; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; UVOMORULIN;

EID: 54349117421     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2008.195     Document Type: Article
Times cited : (102)

References (45)
  • 1
    • 0035048454 scopus 로고    scopus 로고
    • A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons
    • Almeida A, Bolaños JP (2001) A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons. J Neurochem 77: 676-690
    • (2001) J Neurochem , vol.77 , pp. 676-690
    • Almeida, A.1    Bolaños, J.P.2
  • 2
    • 24744467563 scopus 로고    scopus 로고
    • Cdh1/Hct1-APC is essential for the survival of postmitotic neurons
    • Almeida A, Bolanos JP, Moreno S (2005) Cdh1/Hct1-APC is essential for the survival of postmitotic neurons. J Neurosci 25: 8115-8121
    • (2005) J Neurosci , vol.25 , pp. 8115-8121
    • Almeida, A.1    Bolanos, J.P.2    Moreno, S.3
  • 3
    • 1342310736 scopus 로고    scopus 로고
    • Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway
    • Almeida A, Moncada S, Bolaños JP (2004) Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway. Nat Cell Biol 6: 45-51
    • (2004) Nat Cell Biol , vol.6 , pp. 45-51
    • Almeida, A.1    Moncada, S.2    Bolaños, J.P.3
  • 4
    • 1642378661 scopus 로고    scopus 로고
    • Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
    • Bashir T, Dorrello NV, Amador V, Guardavaccaro D, Pagano M (2004) Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase. Nature 428: 190-193
    • (2004) Nature , vol.428 , pp. 190-193
    • Bashir, T.1    Dorrello, N.V.2    Amador, V.3    Guardavaccaro, D.4    Pagano, M.5
  • 5
    • 1542381057 scopus 로고    scopus 로고
    • Cell cycle regulation of neuronal apoptosis in development and disease
    • Becker EBE, Bonni A (2004) Cell cycle regulation of neuronal apoptosis in development and disease. Progr Neurobiol 72: 1-25
    • (2004) Progr Neurobiol , vol.72 , pp. 1-25
    • Becker, E.B.E.1    Bonni, A.2
  • 6
    • 18244413452 scopus 로고    scopus 로고
    • APC(ste9/srw1) promotes degradation of mitotic cyclins in G(1) and is inhibited by cdc2 phosphorylation
    • Blanco MA, Sanchez-Diaz A, de Prada JM, Moreno S (2000) APC(ste9/srw1) promotes degradation of mitotic cyclins in G(1) and is inhibited by cdc2 phosphorylation. EMBO J 19: 3945-3955
    • (2000) EMBO J , vol.19 , pp. 3945-3955
    • Blanco, M.A.1    Sanchez-Diaz, A.2    de Prada, J.M.3    Moreno, S.4
  • 9
    • 0742272184 scopus 로고    scopus 로고
    • Immunohistochemical analysis of protein expression after middle cerebral artery occlusion in mice
    • Erdo F, Trapp T, Mies G, Hossmann KA (2004) Immunohistochemical analysis of protein expression after middle cerebral artery occlusion in mice. Acta Neuropathol 107: 127-136
    • (2004) Acta Neuropathol , vol.107 , pp. 127-136
    • Erdo, F.1    Trapp, T.2    Mies, G.3    Hossmann, K.A.4
  • 10
    • 0033613270 scopus 로고    scopus 로고
    • Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons
    • Gieffers C, Peters BH, Kramer ER, Dotti CG, Peters JM (1999) Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons. Proc Natl Acad Sci USA 96: 11317-11322
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 11317-11322
    • Gieffers, C.1    Peters, B.H.2    Kramer, E.R.3    Dotti, C.G.4    Peters, J.M.5
  • 11
    • 10644255687 scopus 로고    scopus 로고
    • AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test
    • Gould TD, Einat H, Bhat R, Manji HK (2004) AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test. Int J Neuropsychopharmacol 7: 387-390
    • (2004) Int J Neuropsychopharmacol , vol.7 , pp. 387-390
    • Gould, T.D.1    Einat, H.2    Bhat, R.3    Manji, H.K.4
  • 12
    • 0036095082 scopus 로고    scopus 로고
    • EF2-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC-Cdh1
    • Hsu JY, Reimann JDR, Sørensen CS, Lukas J, Jackson PK (2002) EF2-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC-Cdh1. Nat Cell Biol 4: 358-366
    • (2002) Nat Cell Biol , vol.4 , pp. 358-366
    • Hsu, J.Y.1    Reimann, J.D.R.2    Sørensen, C.S.3    Lukas, J.4    Jackson, P.K.5
  • 13
    • 0037011124 scopus 로고    scopus 로고
    • Cell cycle-dependent nuclear export of Cdh1p may contribute to the inactivation of APC/C(Cdh1)
    • Jaquenoud M, van Drogen F, Peter M (2002) Cell cycle-dependent nuclear export of Cdh1p may contribute to the inactivation of APC/C(Cdh1). EMBO J 21: 6515-6526
    • (2002) EMBO J , vol.21 , pp. 6515-6526
    • Jaquenoud, M.1    van Drogen, F.2    Peter, M.3
  • 14
    • 9244263049 scopus 로고    scopus 로고
    • The anaphase-promoting complex regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans
    • Juo P, Kaplan JM (2004) The anaphase-promoting complex regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans. Curr Biol 14: 2057-2062
    • (2004) Curr Biol , vol.14 , pp. 2057-2062
    • Juo, P.1    Kaplan, J.M.2
  • 15
    • 0031664330 scopus 로고    scopus 로고
    • Fission yeast Ste9, a homolog of Hct1/Cdh1 and Fizzy-related, is a novel negative regulator of cell cycle progression during G1-phase
    • Kitamura K, Maekawa H, Shimoda C (1998) Fission yeast Ste9, a homolog of Hct1/Cdh1 and Fizzy-related, is a novel negative regulator of cell cycle progression during G1-phase. Mol Biol Cell 9: 1065-108
    • (1998) Mol Biol Cell , vol.9 , pp. 1065-1108
    • Kitamura, K.1    Maekawa, H.2    Shimoda, C.3
  • 16
    • 0036282745 scopus 로고    scopus 로고
    • Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery
    • Konishi Y, Lehtinen M, Donovan N, Bonni A (2002) Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery. Mol Cell 9: 1005-1016
    • (2002) Mol Cell , vol.9 , pp. 1005-1016
    • Konishi, Y.1    Lehtinen, M.2    Donovan, N.3    Bonni, A.4
  • 17
    • 1142274208 scopus 로고    scopus 로고
    • Cdh1-APC controls axonal growth and patterning in the mammalian brain
    • Konishi Y, Stegmuller J, Matsuda T, Bonni S, Bonni A (2004) Cdh1-APC controls axonal growth and patterning in the mammalian brain. Science 303: 1026-1030
    • (2004) Science , vol.303 , pp. 1026-1030
    • Konishi, Y.1    Stegmuller, J.2    Matsuda, T.3    Bonni, S.4    Bonni, A.5
  • 22
    • 33947519417 scopus 로고    scopus 로고
    • Regulation and function of glycogen synthase kinase-3 isoforms in neuronal survival
    • Liang MH, Chuang DM (2007) Regulation and function of glycogen synthase kinase-3 isoforms in neuronal survival. J Biol Chem 282: 3904-3917
    • (2007) J Biol Chem , vol.282 , pp. 3904-3917
    • Liang, M.H.1    Chuang, D.M.2
  • 23
    • 0344851640 scopus 로고    scopus 로고
    • Neuronal expression of cell cycle-related proteins after brain ischaemia in man
    • Love S (2003) Neuronal expression of cell cycle-related proteins after brain ischaemia in man. Neurosci Lett 353: 29-32
    • (2003) Neurosci Lett , vol.353 , pp. 29-32
    • Love, S.1
  • 25
    • 34347351340 scopus 로고    scopus 로고
    • Aneuploidy and DNA replication in the normal human brain and Alzheimer's disease
    • Mosch B, Morawski M, Mittag A, Lenz D, Tarnok A, Arendt T (2007) Aneuploidy and DNA replication in the normal human brain and Alzheimer's disease. J Neurosci 27: 6859-6867
    • (2007) J Neurosci , vol.27 , pp. 6859-6867
    • Mosch, B.1    Morawski, M.2    Mittag, A.3    Lenz, D.4    Tarnok, A.5    Arendt, T.6
  • 27
    • 0036284778 scopus 로고    scopus 로고
    • The anaphase-promoting complex: Proteolysis in mitosis and beyond
    • Peters JM (2002) The anaphase-promoting complex: proteolysis in mitosis and beyond. Mol Cell 9: 931-943
    • (2002) Mol Cell , vol.9 , pp. 931-943
    • Peters, J.M.1
  • 29
    • 0030738748 scopus 로고    scopus 로고
    • Yeast Hct1 is a regulator of Clb2 cyclin proteolysis
    • Schwab M, Lutum AS, Seufert W (1997) Yeast Hct1 is a regulator of Clb2 cyclin proteolysis. Cell 90: 683-693
    • (1997) Cell , vol.90 , pp. 683-693
    • Schwab, M.1    Lutum, A.S.2    Seufert, W.3
  • 30
    • 0030835478 scopus 로고    scopus 로고
    • Drosophila fizzy-related down-regulates mitotic cyclins and is required for cell proliferation arrest and entry into endocycles
    • Sigrist SJ, Lehner CF (1997) Drosophila fizzy-related down-regulates mitotic cyclins and is required for cell proliferation arrest and entry into endocycles. Cell 90: 671-681
    • (1997) Cell , vol.90 , pp. 671-681
    • Sigrist, S.J.1    Lehner, C.F.2
  • 31
    • 0344668551 scopus 로고    scopus 로고
    • Securin and B-cyclin/CDK are the only essential targets of the APC
    • Thornton BR, Toczyski DP (2003) Securin and B-cyclin/CDK are the only essential targets of the APC. Nat Cell Biol 5: 1090-1094
    • (2003) Nat Cell Biol , vol.5 , pp. 1090-1094
    • Thornton, B.R.1    Toczyski, D.P.2
  • 33
    • 37349046009 scopus 로고    scopus 로고
    • Accumulation of substrates of the anaphase-promoting complex (APC) during human cytomegalovirus infection is associated with the phosphorylation of Cdh1 and the dissociation and relocalization of APC subunits
    • Tran K, Mahr JA, Choi J, Teodoro JG, Green MR, Spector DH (2008) Accumulation of substrates of the anaphase-promoting complex (APC) during human cytomegalovirus infection is associated with the phosphorylation of Cdh1 and the dissociation and relocalization of APC subunits. J Virol 82: 529-537
    • (2008) J Virol , vol.82 , pp. 529-537
    • Tran, K.1    Mahr, J.A.2    Choi, J.3    Teodoro, J.G.4    Green, M.R.5    Spector, D.H.6
  • 34
    • 8844276742 scopus 로고    scopus 로고
    • Independent regulation of synaptic size and activity by the anaphase-promoting complex
    • van Roessel DA, Elliott DA, Robinson IM, Prokop A, Brand AH (2004) Independent regulation of synaptic size and activity by the anaphase-promoting complex. Cell 119: 707-718
    • (2004) Cell , vol.119 , pp. 707-718
    • van Roessel, D.A.1    Elliott, D.A.2    Robinson, I.M.3    Prokop, A.4    Brand, A.H.5
  • 35
    • 0031006939 scopus 로고    scopus 로고
    • Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain
    • Vincent I, Jicha G, Rosado M, Dickson DW (1997) Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain. J Neurosci 17: 3588-3598
    • (1997) J Neurosci , vol.17 , pp. 3588-3598
    • Vincent, I.1    Jicha, G.2    Rosado, M.3    Dickson, D.W.4
  • 36
    • 0030693087 scopus 로고    scopus 로고
    • CDC20 and CDH1: A family of substrate-specific activators of APC-dependent proteolysis
    • Visintin R, Prinz S, Amon A (1997) CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis. Science 278: 460-463
    • (1997) Science , vol.278 , pp. 460-463
    • Visintin, R.1    Prinz, S.2    Amon, A.3
  • 37
    • 0141542665 scopus 로고    scopus 로고
    • Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors
    • Wang J, Liu S, Fu Y, Wang JH, Lu Y (2003) Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors. Nat Neurosci 6: 1039-1047
    • (2003) Nat Neurosci , vol.6 , pp. 1039-1047
    • Wang, J.1    Liu, S.2    Fu, Y.3    Wang, J.H.4    Lu, Y.5
  • 38
    • 1642399624 scopus 로고    scopus 로고
    • Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
    • Wei W, Ayad NG, Wan Y, Zhang GJ, Kirschner MW, Kaelin WG (2004) Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex. Nature 428: 194-198
    • (2004) Nature , vol.428 , pp. 194-198
    • Wei, W.1    Ayad, N.G.2    Wan, Y.3    Zhang, G.J.4    Kirschner, M.W.5    Kaelin, W.G.6
  • 39
    • 2542428253 scopus 로고    scopus 로고
    • Transient cerebral ischemia induces aberrant neuronal cell cycle re-rentry and Alzheimer's disease-like tauopathy in female rats
    • Wen Y, Yang S, Liu R, Brun-Zinkernagels AM, Koulen P, Simpkins JW (2004) Transient cerebral ischemia induces aberrant neuronal cell cycle re-rentry and Alzheimer's disease-like tauopathy in female rats. J Biol Chem 279: 22684-22692
    • (2004) J Biol Chem , vol.279 , pp. 22684-22692
    • Wen, Y.1    Yang, S.2    Liu, R.3    Brun-Zinkernagels, A.M.4    Koulen, P.5    Simpkins, J.W.6
  • 40
    • 0030725561 scopus 로고    scopus 로고
    • A WD repeat protein controls the cell cycle and differentiation by negatively regulating Cdc2/B-type cyclin complexes
    • Yamaguchi S, Murakami H, Okayama H (1997) A WD repeat protein controls the cell cycle and differentiation by negatively regulating Cdc2/B-type cyclin complexes. Mol Biol Cell 8: 2475-2786
    • (1997) Mol Biol Cell , vol.8 , pp. 2475-2786
    • Yamaguchi, S.1    Murakami, H.2    Okayama, H.3
  • 41
    • 0034254639 scopus 로고    scopus 로고
    • Fission yeast Fizzy-related protein srw1p is a G(1)-specific promoter of mitotic cyclin B degradation
    • Yamaguchi S, Okayama H, Nurse P (2000) Fission yeast Fizzy-related protein srw1p is a G(1)-specific promoter of mitotic cyclin B degradation. EMBO J 19: 3968-3977
    • (2000) EMBO J , vol.19 , pp. 3968-3977
    • Yamaguchi, S.1    Okayama, H.2    Nurse, P.3
  • 42
    • 0344241479 scopus 로고    scopus 로고
    • Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease
    • Yang Y, Mufson EJ, Herrup K (2003) Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease. J Neurosci 23: 2557-2563
    • (2003) J Neurosci , vol.23 , pp. 2557-2563
    • Yang, Y.1    Mufson, E.J.2    Herrup, K.3
  • 45
    • 0038485578 scopus 로고    scopus 로고
    • Nuclear localization of the cell cycle regulator CDH1 and its regulation by phosphorylation
    • Zhou Y, Ching YP, Chun AC, Jin DY (2003) Nuclear localization of the cell cycle regulator CDH1 and its regulation by phosphorylation. J Biol Chem 278: 12530-12536
    • (2003) J Biol Chem , vol.278 , pp. 12530-12536
    • Zhou, Y.1    Ching, Y.P.2    Chun, A.C.3    Jin, D.Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.