Heart 6-phosphofructo-2-kinase activation by insulin requires PKB (protein kinase B), but not SGK3 (serum- and glucocorticoid-induced protein kinase 3)

Biochemical Journal

Volumn 431, Issue 2, 2010, Pages 267-275

  Mouton, Véronique ^a   Toussaint, Louise ^a,b   Vertommen, Didier ^a   Gueuning, Marie Agnès ^a   Maisin, Liliane ^a   Havaux, Xavier ^c   Sanchez Canedo, Cossette ^c   Bertrand, Luc ^c   Dequiedt, Franck ^b   Hemmings, Brian A ^d   Hue, Louis ^a   Rider, Mark H ^a  

^a DE DUVE INSTITUTE   (Belgium)

^b Cellular and Molecular Biology Unit   (Belgium)

^c UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^d FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

Author keywords

6 phosphofructo 2 kinase (PFK 2); Glycolysis; Protein kinase B (PKB); Serum and glucocorticoid induced protein kinase 3 (SGK3); Small interfering RNA (siRNA)

Indexed keywords

6-PHOSPHOFRUCTO-2-KINASE (PFK-2); GLYCOLYSIS; INDUCED PROTEINS; PROTEIN KINASE B (PKB); SMALL INTERFERING RNA (SIRNA);

BODY FLUIDS; CHEMICAL ACTIVATION; HEART; INSULIN; PATHOLOGY; PHOSPHORYLATION; RNA; VIRUSES;

PROTEINS;

6 PHOSPHOFRUCTOSE 2 KINASE; INSULIN; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PHOSPHOTRANSFERASE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; SERUM AND GLUCOCORTICOID REGULATED KINASE 3; UNCLASSIFIED DRUG; 6 PHOSPHOFRUCTO 2 KINASE; PROTEIN KINASE INHIBITOR; PYRUVATE DEHYDROGENASE (ACETYL TRANSFERRING) KINASE; PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE; SGK3 PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HEART MUSCLE CELL; HEART PERFUSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; ANIMAL; ANTIBODY SPECIFICITY; BINDING SITE; CATTLE; CELL LINE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; HEART MUSCLE; MALE; METABOLISM; MUTATION; TRANSGENIC MOUSE; WISTAR RAT;

MUS; MUS MUSCULUS; RATTUS; SIMIAN VIRUS 40;

ANIMALS; BINDING SITES; CATTLE; CELL LINE; ENZYME ACTIVATION; HUMANS; INSULIN; MALE; MICE; MICE, TRANSGENIC; MUTATION; MYOCARDIUM; MYOCYTES, CARDIAC; ORGAN SPECIFICITY; PHOSPHOFRUCTOKINASE-2; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; SUBSTRATE SPECIFICITY;

EID: 77957921916     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20101089     Document Type: Article

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