-
1
-
-
12144288066
-
A twist code determines the onset of osteoblast differentiation
-
Bialek P, Kern B, Yang X, Schrock M, Sosic D, Hong N, Wu H, Yu K, Ornitz DM, Olson EN, Justice MJ, Karsenty G. 2004. A twist code determines the onset of osteoblast differentiation. Dev Cell 6:423-435.
-
(2004)
Dev Cell
, vol.6
, pp. 423-435
-
-
Bialek, P.1
Kern, B.2
Yang, X.3
Schrock, M.4
Sosic, D.5
Hong, N.6
Wu, H.7
Yu, K.8
Ornitz, D.M.9
Olson, E.N.10
Justice, M.J.11
Karsenty, G.12
-
2
-
-
0035034603
-
Inactivation of the β-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development
-
Brault V, Moore R, Kutsch S, Ishibashi M, Rowitch DH, McMahon AP, Sommer L, Boussadia O, Kemler R. 2001. Inactivation of the β-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development 128:1253-1264.
-
(2001)
Development
, vol.128
, pp. 1253-1264
-
-
Brault, V.1
Moore, R.2
Kutsch, S.3
Ishibashi, M.4
Rowitch, D.H.5
McMahon, A.P.6
Sommer, L.7
Boussadia, O.8
Kemler, R.9
-
3
-
-
17844372752
-
Wnt/β-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis
-
Day TF, Guo X, Garrett-Beal L, Yang Y. 2005. Wnt/β-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. Dev Cell 8:739-750.
-
(2005)
Dev Cell
, vol.8
, pp. 739-750
-
-
Day, T.F.1
Guo, X.2
Garrett-Beal, L.3
Yang, Y.4
-
4
-
-
0030678549
-
Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
-
Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G. 1997. Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation. Cell 89:747-754.
-
(1997)
Cell
, vol.89
, pp. 747-754
-
-
Ducy, P.1
Zhang, R.2
Geoffroy, V.3
Ridall, A.L.4
Karsenty, G.5
-
5
-
-
3543045594
-
The Fos-related antigen Fra-1 is an activator of bone matrix formation
-
Eferl R, Hoebertz A, Schilling AF, Rath M, Karreth F, Kenner L, Amling M, Wagner EF. 2004. The Fos-related antigen Fra-1 is an activator of bone matrix formation. EMBO J 23:2789-2799.
-
(2004)
EMBO J
, vol.23
, pp. 2789-2799
-
-
Eferl, R.1
Hoebertz, A.2
Schilling, A.F.3
Rath, M.4
Karreth, F.5
Kenner, L.6
Amling, M.7
Wagner, E.F.8
-
6
-
-
25844509347
-
Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression
-
Gaur T, Lengner CJ, Hovhannisyan H, Bhat RA, Bodine PV, Komm BS, Javed A, van Wijnen AJ, Stein JL, Stein GS, Lian JB. 2005. Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression. J Biol Chem 280:33132-33140.
-
(2005)
J Biol Chem
, vol.280
, pp. 33132-33140
-
-
Gaur, T.1
Lengner, C.J.2
Hovhannisyan, H.3
Bhat, R.A.4
Bodine, P.V.5
Komm, B.S.6
Javed, A.7
Van Wijnen, A.J.8
Stein, J.L.9
Stein, G.S.10
Lian, J.B.11
-
7
-
-
0036333736
-
High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage
-
Geoffroy V, Kneissel M, Fournier B, Boyde A, Matthias P. 2002. High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage. Mol Cell Biol 22:6222-6233.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6222-6233
-
-
Geoffroy, V.1
Kneissel, M.2
Fournier, B.3
Boyde, A.4
Matthias, P.5
-
8
-
-
0034920371
-
Impaired ossification in mice lacking the transcription factor Sp3
-
Gollner H, Dani C, Phillips B, Philipsen S, Suske G. 2001. Impaired ossification in mice lacking the transcription factor Sp3. Mech Dev 106:77-83.
-
(2001)
Mech Dev
, vol.106
, pp. 77-83
-
-
Gollner, H.1
Dani, C.2
Phillips, B.3
Philipsen, S.4
Suske, G.5
-
9
-
-
0033548440
-
Cbfa1 isoforms exert functional differences in osteoblast differentiation
-
Harada H, Tagashira S, Fujiwara M, Ogawa S, Katsumata T, Yamaguchi A, Komori T, Nakatsuka M. 1999. Cbfa1 isoforms exert functional differences in osteoblast differentiation. J Biol Chem 274:6972-6978.
-
(1999)
J Biol Chem
, vol.274
, pp. 6972-6978
-
-
Harada, H.1
Tagashira, S.2
Fujiwara, M.3
Ogawa, S.4
Katsumata, T.5
Yamaguchi, A.6
Komori, T.7
Nakatsuka, M.8
-
10
-
-
17844363974
-
Canonical Wnt/β-catenin signaling prevents osteoblasts from differentiating into chondrocytes
-
Hill TP, Spater D, Taketo MM, Birchmeier W, Hartmann C. 2005. Canonical Wnt/β-catenin signaling prevents osteoblasts from differentiating into chondrocytes. Dev Cell 8:727-738.
-
(2005)
Dev Cell
, vol.8
, pp. 727-738
-
-
Hill, T.P.1
Spater, D.2
Taketo, M.M.3
Birchmeier, W.4
Hartmann, C.5
-
11
-
-
13444302715
-
Sequential roles of Hedgehog and Wnt signaling in osteoblast development
-
Hu H, Hilton MJ, Tu X, Yu K, Ornitz DM, Long F. 2005. Sequential roles of Hedgehog and Wnt signaling in osteoblast development. Development 132:49-60.
-
(2005)
Development
, vol.132
, pp. 49-60
-
-
Hu, H.1
Hilton, M.J.2
Tu, X.3
Yu, K.4
Ornitz, D.M.5
Long, F.6
-
12
-
-
4043181957
-
Reciprocal roles of MSX2 in regulation of osteoblast and adipocyte differentiation
-
Ichida F, Nishimura R, Hata K, Matsubara T, Ikeda F, Hisada K, Yatani H, Cao X, Komori T, Yamaguchi A, Yoneda T. 2004. Reciprocal roles of MSX2 in regulation of osteoblast and adipocyte differentiation. J Biol Chem 279:34015-34022.
-
(2004)
J Biol Chem
, vol.279
, pp. 34015-34022
-
-
Ichida, F.1
Nishimura, R.2
Hata, K.3
Matsubara, T.4
Ikeda, F.5
Hisada, K.6
Yatani, H.7
Cao, X.8
Komori, T.9
Yamaguchi, A.10
Yoneda, T.11
-
13
-
-
0346252654
-
Msx2 and Twist cooperatively control the development of the neural crest-derived skeletogenic mesenchyme of the murine skull vault
-
Ishii M, Merrill AE, Chan YS, Gitelman I, Rice DP, Sucov HM, Maxson RE Jr. 2003. Msx2 and Twist cooperatively control the development of the neural crest-derived skeletogenic mesenchyme of the murine skull vault. Development 130:6131-6142.
-
(2003)
Development
, vol.130
, pp. 6131-6142
-
-
Ishii, M.1
Merrill, A.E.2
Chan, Y.S.3
Gitelman, I.4
Rice, D.P.5
Sucov, H.M.6
Maxson Jr., R.E.7
-
14
-
-
33745959553
-
Cb+β regulates Runx2 function isoform-dependently in prostrated bone development
-
in press
-
Kanatani N, Fujita T, Fukayama R, Liu W, Yoshida CA, Moriishi T, Yamana K, Miyazaki T, Toyosawa S, Komori T. 2006. Cb+β regulates Runx2 function isoform-dependently in prostrated bone development. Dev Biol (in press).
-
(2006)
Dev Biol
-
-
Kanatani, N.1
Fujita, T.2
Fukayama, R.3
Liu, W.4
Yoshida, C.A.5
Moriishi, T.6
Yamana, K.7
Miyazaki, T.8
Toyosawa, S.9
Komori, T.10
-
15
-
-
23044448510
-
Repression of Runx2 function by TGF-β through recruitment of class II histone deacetylases by Smad3
-
Kang JS, Alliston T, Delston R, Derynck R. 2005. Repression of Runx2 function by TGF-β through recruitment of class II histone deacetylases by Smad3. EMBO J 24:2543-2555.
-
(2005)
EMBO J
, vol.24
, pp. 2543-2555
-
-
Kang, J.S.1
Alliston, T.2
Delston, R.3
Derynck, R.4
-
16
-
-
0033876760
-
Multilineage differentiation of Cbfa1-deficient calvarial cells in vitro
-
Kobayashi H, Gao Y, Ueta C, Yamaguchi A, Komori T. 2000. Multilineage differentiation of Cbfa1-deficient calvarial cells in vitro. Biochem Biophys Res Commun 273:630-636.
-
(2000)
Biochem Biophys Res Commun
, vol.273
, pp. 630-636
-
-
Kobayashi, H.1
Gao, Y.2
Ueta, C.3
Yamaguchi, A.4
Komori, T.5
-
17
-
-
23844515714
-
NFAT and Osterix cooperatively regulate bone formation
-
Koga T, Matsui Y, Asagiri M, Kodama T, de Crombrugghe B, Nakashima K, Takayanagi H. 2005. NFAT and Osterix cooperatively regulate bone formation. Nat Med 11:880-885.
-
(2005)
Nat Med
, vol.11
, pp. 880-885
-
-
Koga, T.1
Matsui, Y.2
Asagiri, M.3
Kodama, T.4
De Crombrugghe, B.5
Nakashima, K.6
Takayanagi, H.7
-
18
-
-
22644447278
-
Regulation of skeletal development by the Runx family of transcription factors
-
Komori T. 2005. Regulation of skeletal development by the Runx family of transcription factors. J Cell Biochem 95:445-453.
-
(2005)
J Cell Biochem
, vol.95
, pp. 445-453
-
-
Komori, T.1
-
19
-
-
0030684749
-
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
-
Komori T, Yagi H, Nomura S, Yamaguchi A, Sasaki K, Deguchi K, Shimizu Y, Bronson RT, Gao Y, Inada M, Sato M, Okamoto R, Kitamura Y, Yoshiki S, Kishimoto T. 1997. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89:755-764.
-
(1997)
Cell
, vol.89
, pp. 755-764
-
-
Komori, T.1
Yagi, H.2
Nomura, S.3
Yamaguchi, A.4
Sasaki, K.5
Deguchi, K.6
Shimizu, Y.7
Bronson, R.T.8
Gao, Y.9
Inada, M.10
Sato, M.11
Okamoto, R.12
Kitamura, Y.13
Yoshiki, S.14
Kishimoto, T.15
-
20
-
-
1642278652
-
ΔFosB induces osteosclerosis and decreases adipogenesis by two independent cell-autonomous mechanisms
-
Kveiborg M, Sabatakos G, Chiusaroli R, Wu M, Philbrick WM, Home WC, Baron R. 2004. ΔFosB induces osteosclerosis and decreases adipogenesis by two independent cell-autonomous mechanisms. Mol Cell Biol 24:2820-2830.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 2820-2830
-
-
Kveiborg, M.1
Sabatakos, G.2
Chiusaroli, R.3
Wu, M.4
Philbrick, W.M.5
Home, W.C.6
Baron, R.7
-
21
-
-
27444447372
-
Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter
-
Lee MH, Kim YJ, Yoon WJ, Kim JI, Kim BG, Hwang YS, Wozney JM, Chi XZ, Bae SC, Choi KY, Cho JY, Choi JY, Ryoo HM. 2005. Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter. J Biol Chem 280:35579-35587.
-
(2005)
J Biol Chem
, vol.280
, pp. 35579-35587
-
-
Lee, M.H.1
Kim, Y.J.2
Yoon, W.J.3
Kim, J.I.4
Kim, B.G.5
Hwang, Y.S.6
Wozney, J.M.7
Chi, X.Z.8
Bae, S.C.9
Choi, K.Y.10
Cho, J.Y.11
Choi, J.Y.12
Ryoo, H.M.13
-
22
-
-
0030060372
-
Defective bone formation in Krox-20 mutant mice
-
Levi G, Topilko P, Schneider-Maunoury S, Lasagna M, Mantero S, Cancedda R, Charnay P. 1996. Defective bone formation in Krox-20 mutant mice. Development. 122:113-120.
-
(1996)
Development
, vol.122
, pp. 113-120
-
-
Levi, G.1
Topilko, P.2
Schneider-Maunoury, S.3
Lasagna, M.4
Mantero, S.5
Cancedda, R.6
Charnay, P.7
-
23
-
-
0033555425
-
Msx2 gene dosage influences the number of proliferative osteogenic cells in growth centers of the developing murine skull: A possible mechanism for MSX2-mediated craniosynostosis in humans
-
Liu YH, Tang Z, Kundu RK, Wu L, Luo W, Zhu D, Sangiorgi F, Snead ML, Maxson RE. 1999. Msx2 gene dosage influences the number of proliferative osteogenic cells in growth centers of the developing murine skull: A possible mechanism for MSX2-mediated craniosynostosis in humans. Dev Biol 205:260-274.
-
(1999)
Dev Biol
, vol.205
, pp. 260-274
-
-
Liu, Y.H.1
Tang, Z.2
Kundu, R.K.3
Wu, L.4
Luo, W.5
Zhu, D.6
Sangiorgi, F.7
Snead, M.L.8
Maxson, R.E.9
-
24
-
-
0035494469
-
Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures
-
Liu W, Toyosawa S, Furuichi T, Kanatani N, Yoshida C, Liu Y, Himeno M, Narai S, Yamaguchi A, Komori T. 2001. Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures. J Cell Biol 155:157-166.
-
(2001)
J Cell Biol
, vol.155
, pp. 157-166
-
-
Liu, W.1
Toyosawa, S.2
Furuichi, T.3
Kanatani, N.4
Yoshida, C.5
Liu, Y.6
Himeno, M.7
Narai, S.8
Yamaguchi, A.9
Komori, T.10
-
25
-
-
13244283228
-
The interferon-inducible p204 protein acts as a transcriptional coactivator of Cbfa1 and enhances osteoblast differentiation
-
Liu CJ, Chang E, Yu J, Carlson CS, Prazak L, Yu XP, Ding B, Lengyel P, Di Cesare PE. 2005. The interferon-inducible p204 protein acts as a transcriptional coactivator of Cbfa1 and enhances osteoblast differentiation. J Biol Chem 280:2788-2796.
-
(2005)
J Biol Chem
, vol.280
, pp. 2788-2796
-
-
Liu, C.J.1
Chang, E.2
Yu, J.3
Carlson, C.S.4
Prazak, L.5
Yu, X.P.6
Ding, B.7
Lengyel, P.8
Di Cesare, P.E.9
-
26
-
-
8444251784
-
The Wnt signaling pathway in development and disease
-
Logan CY, Nusse R. 2004. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 20:781-810.
-
(2004)
Annu Rev Cell Dev Biol
, vol.20
, pp. 781-810
-
-
Logan, C.Y.1
Nusse, R.2
-
27
-
-
0037059614
-
The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation
-
Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B. 2002. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 108:17-29.
-
(2002)
Cell
, vol.108
, pp. 17-29
-
-
Nakashima, K.1
Zhou, X.2
Kunkel, G.3
Zhang, Z.4
Deng, J.M.5
Behringer, R.R.6
De Crombrugghe, B.7
-
28
-
-
0030666372
-
Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
-
Otto F, Thornell AP, Crompton T, Denzel A, Gilmour KC, Rosewell IR, Stamp GW, Beddington RS, Mundlos S, Olsen BR, Selby PB, Owen MJ. 1997. Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 89:765-771.
-
(1997)
Cell
, vol.89
, pp. 765-771
-
-
Otto, F.1
Thornell, A.P.2
Crompton, T.3
Denzel, A.4
Gilmour, K.C.5
Rosewell, I.R.6
Stamp, G.W.7
Beddington, R.S.8
Mundlos, S.9
Olsen, B.R.10
Selby, P.B.11
Owen, M.J.12
-
29
-
-
0036558218
-
The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development
-
Robledo RF, Rajan L, Li X, Lufkin T. 2002. The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. Genes Dev 16:1089-1101.
-
(2002)
Genes Dev
, vol.16
, pp. 1089-1101
-
-
Robledo, R.F.1
Rajan, L.2
Li, X.3
Lufkin, T.4
-
30
-
-
0034029571
-
Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation
-
Satokata I, Ma L, Ohshima H, Bei M, Woo I, Nishizawa K, Maeda T, Takano Y, Uchiyama M, Heaney S, Peters H, Tang Z, Maxson R, Maas R. 2000. Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation. Nat Genet 4:391-395.
-
(2000)
Nat Genet
, vol.4
, pp. 391-395
-
-
Satokata, I.1
Ma, L.2
Ohshima, H.3
Bei, M.4
Woo, I.5
Nishizawa, K.6
Maeda, T.7
Takano, Y.8
Uchiyama, M.9
Heaney, S.10
Peters, H.11
Tang, Z.12
Maxson, R.13
Maas, R.14
-
31
-
-
24744458827
-
Cooperative interactions between activating transcription factor 4 and Runx2/Cbfa1 stimulate osteoblast-specific osteocalcin gene expression
-
Xiao G, Jiang D, Ge C, Zhao Z, Lai Y, Boules H, Phimphilai M, Yang X, Karsenty G, Franceschi RT. 2005. Cooperative interactions between activating transcription factor 4 and Runx2/Cbfa1 stimulate osteoblast-specific osteocalcin gene expression. J Biol Chem 280:30689-30696.
-
(2005)
J Biol Chem
, vol.280
, pp. 30689-30696
-
-
Xiao, G.1
Jiang, D.2
Ge, C.3
Zhao, Z.4
Lai, Y.5
Boules, H.6
Phimphilai, M.7
Yang, X.8
Karsenty, G.9
Franceschi, R.T.10
-
32
-
-
11144357428
-
ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome
-
Yang X, Matsuda K, Bialek P, Jacquot S, Masuoka HC, Schinke T, Li L, Brancorsini S, Sassone-Corsi P, Townes TM, Hanauer A, Karsenty G. 2004. ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell 117:387-398.
-
(2004)
Cell
, vol.117
, pp. 387-398
-
-
Yang, X.1
Matsuda, K.2
Bialek, P.3
Jacquot, S.4
Masuoka, H.C.5
Schinke, T.6
Li, L.7
Brancorsini, S.8
Sassone-Corsi, P.9
Townes, T.M.10
Hanauer, A.11
Karsenty, G.12
-
33
-
-
0036900947
-
Core-binding factor β interacts with Runx2 and is required for skeletal development
-
Yoshida CA, Furuichi T, Fujita T, Fukuyama R, Kanatani N, Kobayashi S, Satake M, Takada K, Komori T. 2002. Core-binding factor β interacts with Runx2 and is required for skeletal development. Nat Genet 32:633-638.
-
(2002)
Nat Genet
, vol.32
, pp. 633-638
-
-
Yoshida, C.A.1
Furuichi, T.2
Fujita, T.3
Fukuyama, R.4
Kanatani, N.5
Kobayashi, S.6
Satake, M.7
Takada, K.8
Komori, T.9
|