Genetic and pharmacological evidence that 5-HT2C receptor activation, but not inhibition, affects motivation to feed under a progressive ratio schedule of reinforcement

Pharmacology Biochemistry and Behavior

Volumn 97, Issue 1, 2010, Pages 170-178

  Fletcher, Paul J ^a,b   Sinyard, Judy ^a   Higgins, Guy A ^b,c  

^a CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c CanCog Technologies Incorporated   (Canada)

Author keywords

5 HT2C receptor null mutant mouse; 5 HT2C receptors; Feeding; Motivation; Progressive ratio schedule; Ro60 0175; SB242084

Indexed keywords

2 (6 CHLORO 5 FLUORO 1 INDOLYL) 1 METHYLETHYLAMINE; 6 CHLORO 5 METHYL 1 [[2 [(2 METHYL 3 PYRIDYL)OXY] 5 PYRIDYL]CARBAMOYL]INDOLINE; COCAINE; SEROTONIN 2C AGONIST; SEROTONIN 2C RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; FEEDING BEHAVIOR; FOOD INTAKE; GENE DISRUPTION; MALE; MOTIVATION; NONHUMAN; NUTRITIONAL STATUS; PERFORMANCE; PRIORITY JOURNAL; RAT; REINFORCEMENT; SIGNAL TRANSDUCTION;

ANIMALS; FEEDING BEHAVIOR; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTIVATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, SEROTONIN, 5-HT2C; REINFORCEMENT (PSYCHOLOGY); REINFORCEMENT SCHEDULE; SEROTONIN 5-HT2 RECEPTOR AGONISTS; SEROTONIN 5-HT2 RECEPTOR ANTAGONISTS;

ANIMALIA; MUS; RATTUS;

EID: 77957752613     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2010.07.002     Document Type: Article

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