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Volumn 31, Issue 10, 2010, Pages 1258-1266

Adiponectin resistance and vascular dysfunction in the hyperlipidemic state

Author keywords

adiponectin; endothelial dysfunction; hyperlipidemia; insulin; nitric oxide

Indexed keywords

ADIPONECTIN;

EID: 77957738572     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2010.95     Document Type: Review
Times cited : (21)

References (87)
  • 1
    • 0031923033 scopus 로고    scopus 로고
    • Early activation of vascular endothelium in nonobese, nondiabetic essential hypertensive patients with multiple metabolic abnormalities
    • Ferri C, Desideri G, Baldoncini R, Bellini C, De Angelis C, Mazzocchi C, et al. Early activation of vascular endothelium in nonobese, nondiabetic essential hypertensive patients with multiple metabolic abnormalities. Diabetes 1998;47:660-7.
    • (1998) Diabetes , vol.47 , pp. 660-667
    • Ferri, C.1    Desideri, G.2    Baldoncini, R.3    Bellini, C.4    De Angelis, C.5    Mazzocchi, C.6
  • 2
    • 0029977757 scopus 로고    scopus 로고
    • Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance
    • Steinberg HO, Chaker H, Leaming R, Johnson A, Brechtel G, Baron A P N. Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J Clin Invest 1996;97:2601-10.
    • (1996) J. Clin. Invest. , vol.97 , pp. 2601-2610
    • Steinberg, H.O.1    Chaker, H.2    Leaming, R.3    Johnson, A.4    Brechtel, G.5    Baron, A.P.N.6
  • 4
    • 0034881391 scopus 로고    scopus 로고
    • The adipocytesecreted protein Acrp30 enhances hepatic insulin action
    • Berg AH, Combs TP, Du X, Brownlee M, Scherer PE. The adipocytesecreted protein Acrp30 enhances hepatic insulin action. Nat Med 2001;7:947-53.
    • (2001) Nat. Med. , vol.7 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5
  • 5
    • 0242581695 scopus 로고    scopus 로고
    • Adiponectin stimulates production of nitric oxide in vascular endothelial cells
    • Chen H, Montagnani M, Funahashi T, Shimomura I, Quon MJ. Adiponectin stimulates production of nitric oxide in vascular endothelial cells. J Biol Chem 2003;278:45021-6.
    • (2003) J. Biol. Chem. , vol.278 , pp. 45021-45026
    • Chen, H.1    Montagnani, M.2    Funahashi, T.3    Shimomura, I.4    Quon, M.J.5
  • 8
    • 33646394578 scopus 로고    scopus 로고
    • Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: Role of intramuscular accumulation of lipid metabolites
    • Lee JS, Pinnamaneni SK, Eo SJ, Cho IH, Pyo JH, Kim CK, et al. Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites. J Appl Physiol 2006;100:1467-74.
    • (2006) J. Appl. Physiol. , vol.100 , pp. 1467-1474
    • Lee, J.S.1    Pinnamaneni, S.K.2    Eo, S.J.3    Cho, I.H.4    Pyo, J.H.5    Kim, C.K.6
  • 9
    • 34547138662 scopus 로고    scopus 로고
    • Globular adiponectin resistance develops independently of impaired insulin-stimulated glucose transport in soleus muscle from high-fat-fed rats
    • Mullen KL, Smith AC, Junkin KA, Dyck DJ. Globular adiponectin resistance develops independently of impaired insulin-stimulated glucose transport in soleus muscle from high-fat-fed rats. Am J Physiol Endocrinol Metab 2007;293: E83-90.
    • (2007) Am. J. Physiol. Endocrinol. Metab. , vol.293
    • Mullen, K.L.1    Smith, A.C.2    Junkin, K.A.3    Dyck, D.J.4
  • 10
    • 0035839532 scopus 로고    scopus 로고
    • Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser (1179)
    • Montagnani M, Chen H, Barr VA, Quon MJ. Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser (1179). J Biol Chem 2001;276:30392-8.
    • (2001) J. Biol. Chem. , vol.276 , pp. 30392-30398
    • Montagnani, M.1    Chen, H.2    Barr, V.A.3    Quon, M.J.4
  • 11
    • 13844296424 scopus 로고    scopus 로고
    • Insulin-stimulated endothelial nitric oxide release is calcium independent and mediated via protein kinase B
    • Hartell NA, Archer HE, Bailey CJ. Insulin-stimulated endothelial nitric oxide release is calcium independent and mediated via protein kinase B. Biochem Pharmacol 2005;69:781-90.
    • (2005) Biochem. Pharmacol. , vol.69 , pp. 781-790
    • Hartell, N.A.1    Archer, H.E.2    Bailey, C.J.3
  • 12
    • 0030884022 scopus 로고    scopus 로고
    • Endothelial dysfunc tion: Cause of the insulin resistance syndrome
    • Pinkney JH, Stehouwer CD, Coppack SW, Yudkin JS. Endothelial dysfunc tion: cause of the insulin resistance syndrome. Diabetes 1997;46 Suppl 2: S9-13.
    • (1997) Diabetes , vol.46 , Issue.2 SUPPL.
    • Pinkney, J.H.1    Stehouwer, C.D.2    Coppack, S.W.3    Yudkin, J.S.4
  • 13
    • 0025292440 scopus 로고
    • Decreased effect of insulin to stimulate skeletal muscle blood fow in obese man. A novel mechanism for insulin resistance
    • Laakso M, Edelman SV, Brechtel G, Baron A P N. Decreased effect of insulin to stimulate skeletal muscle blood fow in obese man. A novel mechanism for insulin resistance. J Clin Invest 1990;85:1844-52.
    • (1990) J. Clin. Invest. , vol.85 , pp. 1844-1852
    • Laakso, M.1    Edelman, S.V.2    Brechtel, G.3    Baron, A.P.N.4
  • 14
    • 0032719024 scopus 로고    scopus 로고
    • Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats
    • Jiang ZY, Lin YW, Clemont A, Feener EP, Hein KD, Igarashi M, et al. Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats. J Clin Invest 1999;104:447-57.
    • (1999) J. Clin. Invest. , vol.104 , pp. 447-457
    • Jiang, Z.Y.1    Lin, Y.W.2    Clemont, A.3    Feener, E.P.4    Hein, K.D.5    Igarashi, M.6
  • 15
    • 0032564279 scopus 로고    scopus 로고
    • Endothelin ETA receptor blockade restores NO-mediated endothelial function and inhibits atherosclerosis in apolipoprotein E-deficient mice
    • Barton M, Haudenschild CC, d'Uscio LV, Shaw S, Munter K, Luscher TF. Endothelin ETA receptor blockade restores NO-mediated endothelial function and inhibits atherosclerosis in apolipoprotein E-deficient mice. Proc Natl Acad Sci USA 1998;95:14367-72.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 14367-14372
    • Barton, M.1    Haudenschild, C.C.2    D'Uscio, L.V.3    Shaw, S.4    Munter, K.5    Luscher, T.F.6
  • 17
    • 0030781578 scopus 로고    scopus 로고
    • Persistent elevation and metabolic dependence of circulating E-selectin after delivery in women with gestational diabetes mellitus
    • Kautzky-Willer A, Fasching P, Jilma B, Waldhausl W, Wagner OF. Persistent elevation and metabolic dependence of circulating E-selectin after delivery in women with gestational diabetes mellitus. J Clin Endocrinol Metab 1997;82:4117-21.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 4117-4121
    • Kautzky-Willer, A.1    Fasching, P.2    Jilma, B.3    Waldhausl, W.4    Wagner, O.F.5
  • 22
    • 0037180472 scopus 로고    scopus 로고
    • Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice
    • Okamoto Y, Kihara S, Ouchi N, Nishida M, Arita Y, Kumada M, et al. Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice. Circulation 2002;106:2767-70.
    • (2002) Circulation , vol.106 , pp. 2767-2770
    • Okamoto, Y.1    Kihara, S.2    Ouchi, N.3    Nishida, M.4    Arita, Y.5    Kumada, M.6
  • 23
    • 0037129861 scopus 로고    scopus 로고
    • Adipocyte-derived plasma protein adiponectin acts as a plateletderived growth factor-BB-binding protein and regulates growth factorinduced common postreceptor signal in vascular smooth muscle cell
    • Arita Y, Kihara S, Ouchi N, Maeda K, Kuriyama H, Okamoto Y, et al. Adipocyte-derived plasma protein adiponectin acts as a plateletderived growth factor-BB-binding protein and regulates growth factorinduced common postreceptor signal in vascular smooth muscle cell. Circulation 2002;105:2893-8.
    • (2002) Circulation , vol.105 , pp. 2893-2898
    • Arita, Y.1    Kihara, S.2    Ouchi, N.3    Maeda, K.4    Kuriyama, H.5    Okamoto, Y.6
  • 24
    • 0034641647 scopus 로고    scopus 로고
    • Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway
    • Ouchi N, Kihara S, Arita Y, Okamoto Y, Maeda K, Kuriyama H, et al. Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation 2000;102:1296-301.
    • (2000) Circulation , vol.102 , pp. 1296-1301
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3    Okamoto, Y.4    Maeda, K.5    Kuriyama, H.6
  • 25
    • 0842332231 scopus 로고    scopus 로고
    • Adiponectin suppresses proliferation and superoxide generation and enhances eNOS activity in endothelial cells treated with oxidized LDL
    • Motoshima H, Wu X, Mahadev K, Goldstein BJ. Adiponectin suppresses proliferation and superoxide generation and enhances eNOS activity in endothelial cells treated with oxidized LDL. Biochem Biophys Res Commun 2004;315:264-71.
    • (2004) Biochem. Biophys. Res. Commun. , vol.315 , pp. 264-271
    • Motoshima, H.1    Wu, X.2    Mahadev, K.3    Goldstein, B.J.4
  • 26
    • 0346463030 scopus 로고    scopus 로고
    • Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells
    • DOI 10.1074/jbc.M310389200
    • Ouchi N, Kobayashi H, Kihara S, Kumada M, Sato K, Inoue T, et al. Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells. J Biol Chem 2004;279:1304-9. (Pubitemid 38082655)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.2 , pp. 1304-1309
    • Ouchi, N.1    Kobayashi, H.2    Kihara, S.3    Kumada, M.4    Sato, K.5    Inoue, T.6    Funahashi, T.7    Walsh, K.8
  • 27
    • 0036851817 scopus 로고    scopus 로고
    • Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
    • Yamauchi T, Kamon J, Minokoshi Y, Ito Y, Waki H, Uchida S, et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 2002;8:1288-95.
    • (2002) Nat. Med. , vol.8 , pp. 1288-1295
    • Yamauchi, T.1    Kamon, J.2    Minokoshi, Y.3    Ito, Y.4    Waki, H.5    Uchida, S.6
  • 28
    • 0035933369 scopus 로고    scopus 로고
    • Acute regulation of fatty acid oxidation and AMP-activated protein kinase in human umbilical vein endothelial cells
    • Dagher Z, Ruderman N, Tornheim K, Ido Y. Acute regulation of fatty acid oxidation and AMP-activated protein kinase in human umbilical vein endothelial cells. Circ Res 2001;88:1276-82.
    • (2001) Circ. Res. , vol.88 , pp. 1276-1282
    • Dagher, Z.1    Ruderman, N.2    Tornheim, K.3    Ido, Y.4
  • 29
    • 12944302597 scopus 로고    scopus 로고
    • Globular adiponectin increases GLUT4 translocation and glucose uptake but reduces glycogen synthesis in rat skeletal muscle cells
    • Ceddia RB, Somwar R, Maida A, Fang X, Bikopoulos G, Sweeney G. Globular adiponectin increases GLUT4 translocation and glucose uptake but reduces glycogen synthesis in rat skeletal muscle cells. Diabetologia 2005;48:132-9.
    • (2005) Diabetologia , vol.48 , pp. 132-139
    • Ceddia, R.B.1    Somwar, R.2    Maida, A.3    Fang, X.4    Bikopoulos, G.5    Sweeney, G.6
  • 30
    • 0034074153 scopus 로고    scopus 로고
    • 5-Aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase
    • Lochhead PA, Salt IP, Walker KS, Hardie DG, Sutherland C. 5-Aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase. Diabetes 2000;49:896-903.
    • (2000) Diabetes , vol.49 , pp. 896-903
    • Lochhead, P.A.1    Salt, I.P.2    Walker, K.S.3    Hardie, D.G.4    Sutherland, C.5
  • 31
    • 0037462684 scopus 로고    scopus 로고
    • Globular adiponectin protected ob/ob mice from diabetes and ApoE-defcient mice from atherosclerosis
    • Yamauchi T, Kamon J, Waki H, Imai Y, Shimozawa N, Hioki K, et al. Globular adiponectin protected ob/ob mice from diabetes and ApoE-defcient mice from atherosclerosis. J Biol Chem 2003;278:2461-8.
    • (2003) J. Biol. Chem. , vol.278 , pp. 2461-2468
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3    Imai, Y.4    Shimozawa, N.5    Hioki, K.6
  • 32
    • 17944365228 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
    • Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 2001;7:941-6.
    • (2001) Nat. Med. , vol.7 , pp. 941-946
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3    Terauchi, Y.4    Kubota, N.5    Hara, K.6
  • 33
    • 33750578279 scopus 로고    scopus 로고
    • Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha
    • Yoon MJ, Lee GY, Chung JJ, Ahn YH, Hong SH, Kim JB. Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha. Diabetes 2006;55:2562-70.
    • (2006) Diabetes , vol.55 , pp. 2562-2570
    • Yoon, M.J.1    Lee, G.Y.2    Chung, J.J.3    Ahn, Y.H.4    Hong, S.H.5    Kim, J.B.6
  • 35
    • 0037020170 scopus 로고    scopus 로고
    • Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis
    • Matsuda M, Shimomura I, Sata M, Arita Y, Nishida M, Maeda N, et al. Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis. J Biol Chem 2002;277:37487-91.
    • (2002) J. Biol. Chem. , vol.277 , pp. 37487-37491
    • Matsuda, M.1    Shimomura, I.2    Sata, M.3    Arita, Y.4    Nishida, M.5    Maeda, N.6
  • 36
    • 59149084060 scopus 로고    scopus 로고
    • Endothelial dysfunction in adiponectin defciency and its mechanisms involved
    • Cao Y, Tao L, Yuan Y, Jiao X, Lau WB, Wang Y, et al. Endothelial dysfunction in adiponectin defciency and its mechanisms involved. J Mol Cell Cardiol 2009;46:413-9.
    • (2009) J. Mol. Cell. Cardiol. , vol.46 , pp. 413-419
    • Cao, Y.1    Tao, L.2    Yuan, Y.3    Jiao, X.4    Lau, W.B.5    Wang, Y.6
  • 37
    • 37149015513 scopus 로고    scopus 로고
    • Adiponectin improves endothelial function in hyperlipidemic rats by reducing oxidative/nitrative stress and differential regulation of eNOS/iNOS activity
    • Li R, Wang WQ, Zhang H, Yang X, Fan Q, Christopher TA, et al. Adiponectin improves endothelial function in hyperlipidemic rats by reducing oxidative/nitrative stress and differential regulation of eNOS/iNOS activity. Am J Physiol Endocrinol Metab 2007;293: E1703-8.
    • (2007) Am. J. Physiol. Endocrinol. Metab. , vol.293
    • Li, R.1    Wang, W.Q.2    Zhang, H.3    Yang, X.4    Fan, Q.5    Christopher, T.A.6
  • 38
    • 33748310586 scopus 로고    scopus 로고
    • Adiponectin suppression of high-glucose-induced reactive oxygen species in vascular endothelial cells: Evidence for involvement of a cAMP signaling pathway
    • Ouedraogo R, Wu X, Xu SQ, Fuchsel L, Motoshima H, Mahadev K, et al. Adiponectin suppression of high-glucose-induced reactive oxygen species in vascular endothelial cells: evidence for involvement of a cAMP signaling pathway. Diabetes 2006;55:1840-6.
    • (2006) Diabetes , vol.55 , pp. 1840-1846
    • Ouedraogo, R.1    Wu, X.2    Xu, S.Q.3    Fuchsel, L.4    Motoshima, H.5    Mahadev, K.6
  • 39
    • 0034141636 scopus 로고    scopus 로고
    • LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphoryl ated by cAMP-dependent protein kinase (PKA) and prenylated in vivo
    • Collins SP, Reoma JL, Gamm DM, Uhler MD. LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphoryl ated by cAMP-dependent protein kinase (PKA) and prenylated in vivo. Biochem J 2000;345:673-80.
    • (2000) Biochem. J. , vol.345 , pp. 673-680
    • Collins, S.P.1    Reoma, J.L.2    Gamm, D.M.3    Uhler, M.D.4
  • 40
    • 0033943576 scopus 로고    scopus 로고
    • ENOS-overexpressing endothelial cells inhibit platelet aggregation and smooth muscle cell proliferation in vitro
    • Kader KN, Akella R, Ziats NP, Lakey LA, Harasaki H, Ranieri JP, et al. eNOS-overexpressing endothelial cells inhibit platelet aggregation and smooth muscle cell proliferation in vitro. Tissue Eng 2000;6:241-51.
    • (2000) Tissue Eng. , vol.6 , pp. 241-251
    • Kader, K.N.1    Akella, R.2    Ziats, N.P.3    Lakey, L.A.4    Harasaki, H.5    Ranieri, J.P.6
  • 41
    • 0024553336 scopus 로고
    • Nitric oxide-generating vasodilators and 8-bromocyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells
    • Garg UC, Hassid A. Nitric oxide-generating vasodilators and 8-bromocyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest 1989;83:1774-7.
    • (1989) J. Clin. Invest. , vol.83 , pp. 1774-1777
    • Garg, U.C.1    Hassid, A.2
  • 42
    • 58849101696 scopus 로고    scopus 로고
    • Endothelial nitric oxide deficiency reduces MMP-13-mediated cleavage of ICAM-1 in vascular endothelium: A role in atherosclerosis
    • Tarin C, Gomez M, Calvo E, Lopez JA, Zaragoza C. Endothelial nitric oxide deficiency reduces MMP-13-mediated cleavage of ICAM-1 in vascular endothelium: a role in atherosclerosis. Arterioscler Thromb Vasc Biol 2009;29:27-32.
    • (2009) Arterioscler Thromb. Vasc. Biol. , vol.29 , pp. 27-32
    • Tarin, C.1    Gomez, M.2    Calvo, E.3    Lopez, J.A.4    Zaragoza, C.5
  • 43
    • 0027396266 scopus 로고
    • Diminished basal nitric oxide release after myocardial ischemia and reperfusion promotes neutrophil adherence to coronary endothelium
    • Ma XL, Weyrich AS, Lefer DJ, Lefer AM. Diminished basal nitric oxide release after myocardial ischemia and reperfusion promotes neutrophil adherence to coronary endothelium. Circ Res 1993;72:403-12.
    • (1993) Circ. Res. , vol.72 , pp. 403-412
    • Ma, X.L.1    Weyrich, A.S.2    Lefer, D.J.3    Lefer, A.M.4
  • 44
    • 57549088860 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor alpha-stimulated monocyte adhesion to human aortic endothelial cells by AMP-activated protein kinase
    • Ewart MA, Kohlhaas CF, Salt IP. Inhibition of tumor necrosis factor alpha-stimulated monocyte adhesion to human aortic endothelial cells by AMP-activated protein kinase. Arterioscler Thromb Vasc Biol 2008;28:2255-7.
    • (2008) Arterioscler Thromb. Vasc. Biol. , vol.28 , pp. 2255-2257
    • Ewart, M.A.1    Kohlhaas, C.F.2    Salt, I.P.3
  • 45
    • 0034234572 scopus 로고    scopus 로고
    • Rebound from nitric oxide inhibition triggers enhanced monocyte activation and chemotaxis
    • Magazine HI, Chang J, Goumon Y, Stefano GB. Rebound from nitric oxide inhibition triggers enhanced monocyte activation and chemotaxis. J Immunol 2000;165:102-7.
    • (2000) J. Immunol. , vol.165 , pp. 102-107
    • Magazine, H.I.1    Chang, J.2    Goumon, Y.3    Stefano, G.B.4
  • 46
    • 0342378190 scopus 로고    scopus 로고
    • Dietary L-arginine reduces the progression of atherosclerosis in cholesterol-fed rabbits: Comparison with lovastatin
    • Boger RH, Bode-Boger SM, Brandes RP, Phivthong-Ngam L, Bohme M, Nafe R, et al. Dietary L-arginine reduces the progression of atherosclerosis in cholesterol-fed rabbits: comparison with lovastatin. Circulation 1997;96:1282-90.
    • (1997) Circulation , vol.96 , pp. 1282-1290
    • Boger, R.H.1    Bode-Boger, S.M.2    Brandes, R.P.3    Phivthong-Ngam, L.4    Bohme, M.5    Nafe, R.6
  • 47
    • 0028233138 scopus 로고
    • NADH oxidoreductase is a major source of superoxide anion in bovine coronary artery endothelium
    • Mohazzab KM, Kaminski PM, Wolin MS. NADH oxidoreductase is a major source of superoxide anion in bovine coronary artery endothelium. Am J Physiol 1994;266: H2568-72.
    • (1994) Am. J. Physiol. , vol.266
    • Mohazzab, K.M.1    Kaminski, P.M.2    Wolin, M.S.3
  • 48
    • 0032171425 scopus 로고    scopus 로고
    • The basic chemistry of nitrogen monoxide and peroxynitrite
    • Koppenol WH. The basic chemistry of nitrogen monoxide and peroxynitrite. Free Radic Biol Med 1998;25:385-91.
    • (1998) Free Radic Biol. Med. , vol.25 , pp. 385-391
    • Koppenol, W.H.1
  • 50
    • 0028123578 scopus 로고
    • Reduced microvascular hyperaemia in subjects at risk of developing type 2 (non-insulindependent) diabetes mellitus
    • Jaap AJ, Hammersley MS, Shore AC, Tooke JE. Reduced microvascular hyperaemia in subjects at risk of developing type 2 (non-insulindependent) diabetes mellitus. Diabetologia 1994;37:214-6.
    • (1994) Diabetologia , vol.37 , pp. 214-216
    • Jaap, A.J.1    Hammersley, M.S.2    Shore, A.C.3    Tooke, J.E.4
  • 53
    • 0037003369 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and impaired vasomotor function in type 2 diabetes mellitus
    • Tan KC, O K, Chow WS, Ai VH, Siow YL, Lam KS. Hyperhomocysteinemia and impaired vasomotor function in type 2 diabetes mellitus. Eur J Clin Invest 2002;32:328-34.
    • (2002) Eur. J. Clin. Invest. , vol.32 , pp. 328-334
    • Tan, K.C.1    Chow, W.S.2    Ai, V.H.3    Siow, Y.L.4    Lam, K.S.5
  • 54
  • 55
    • 0344848578 scopus 로고    scopus 로고
    • Human diabetes is associated with hyperreactivity of vascular smooth muscle cells due to altered subcellular Ca2+ distribution
    • Fleischhacker E, Esenabhalu VE, Spitaler M, Holzmann S, Skrabal F, Koidl B, et al. Human diabetes is associated with hyperreactivity of vascular smooth muscle cells due to altered subcellular Ca2+ distribution. Diabetes 1999;48:1323-30.
    • (1999) Diabetes , vol.48 , pp. 1323-1330
    • Fleischhacker, E.1    Esenabhalu, V.E.2    Spitaler, M.3    Holzmann, S.4    Skrabal, F.5    Koidl, B.6
  • 56
    • 0033661262 scopus 로고    scopus 로고
    • Diabetes in the Goto-Kakizaki rat is accompanied by impaired insulin-mediated myosin-bound phosphatase activation and vascular smooth muscle cell relaxation
    • Sandu OA, Ragolia L, Begum N. Diabetes in the Goto-Kakizaki rat is accompanied by impaired insulin-mediated myosin-bound phosphatase activation and vascular smooth muscle cell relaxation. Diabetes 2000;49:2178-89.
    • (2000) Diabetes , vol.49 , pp. 2178-2189
    • Sandu, O.A.1    Ragolia, L.2    Begum, N.3
  • 57
    • 0037155132 scopus 로고    scopus 로고
    • Active Rho kinase (ROK-alpha) associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells
    • Begum N, Sandu OA, Ito M, Lohmann SM, Smolenski A. Active Rho kinase (ROK-alpha) associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells. J Biol Chem 2002;277:6214-22.
    • (2002) J. Biol. Chem. , vol.277 , pp. 6214-6222
    • Begum, N.1    Sandu, O.A.2    Ito, M.3    Lohmann, S.M.4    Smolenski, A.5
  • 59
    • 0141924849 scopus 로고    scopus 로고
    • Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin
    • Waki H, Yamauchi T, Kamon J, Ito Y, Uchida S, Kita S, et al. Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin. J Biol Chem 2003;278:40352-63.
    • (2003) J. Biol. Chem. , vol.278 , pp. 40352-40363
    • Waki, H.1    Yamauchi, T.2    Kamon, J.3    Ito, Y.4    Uchida, S.5    Kita, S.6
  • 60
    • 12944331141 scopus 로고    scopus 로고
    • Serum adiponectin as a biomarker for in vivo PPARgamma activation and PPARgamma agonist-induced efficacy on insulin sensitization/lipid lowering in rats
    • Yang B, Brown KK, Chen L, Carrick KM, Clifton LG, McNulty JA, et al. Serum adiponectin as a biomarker for in vivo PPARgamma activation and PPARgamma agonist-induced efficacy on insulin sensitization/lipid lowering in rats. BMC Pharmacol 2004;4:23.
    • (2004) BMC Pharmacol. , vol.4 , pp. 23
    • Yang, B.1    Brown, K.K.2    Chen, L.3    Carrick, K.M.4    Clifton, L.G.5    McNulty, J.A.6
  • 61
    • 0035663963 scopus 로고    scopus 로고
    • Endogenous glucose production is inhibited by the adipose-derived protein Acrp30
    • Combs TP, Berg AH, Obici S, Scherer PE, Rossetti L. Endogenous glucose production is inhibited by the adipose-derived protein Acrp30. J Clin Invest 2001;108:1875-81.
    • (2001) J. Clin. Invest. , vol.108 , pp. 1875-1881
    • Combs, T.P.1    Berg, A.H.2    Obici, S.3    Scherer, P.E.4    Rossetti, L.5
  • 62
    • 33846877211 scopus 로고    scopus 로고
    • Maintenance of adiponectin attenuates insulin resistance induced by dietary conjugated linoleic acid in mice
    • Purushotham A, Wendel AA, Liu LF, Belury MA. Maintenance of adiponectin attenuates insulin resistance induced by dietary conjugated linoleic acid in mice. J Lipid Res 2007;48:444-52.
    • (2007) J. Lipid Res. , vol.48 , pp. 444-452
    • Purushotham, A.1    Wendel, A.A.2    Liu, L.F.3    Belury, M.A.4
  • 63
    • 4243645912 scopus 로고    scopus 로고
    • Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: A potential mechanism of insulin sensitization
    • Combs TP, Wagner JA, Berger J, Doebber T, Wang WJ, Zhang BB, et al. Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization. Endocrinology 2002;143:998-1007.
    • (2002) Endocrinology , vol.143 , pp. 998-1007
    • Combs, T.P.1    Wagner, J.A.2    Berger, J.3    Doebber, T.4    Wang, W.J.5    Zhang, B.B.6
  • 65
    • 33644699965 scopus 로고    scopus 로고
    • The stimulatory effect of globular adiponectin on insulin-stimulated glucose uptake and fatty acid oxidation is impaired in skeletal muscle from obese subjects
    • Bruce CR, Mertz VA, Heigenhauser GJ, Dyck DJ. The stimulatory effect of globular adiponectin on insulin-stimulated glucose uptake and fatty acid oxidation is impaired in skeletal muscle from obese subjects. Diabetes 2005;54:3154-60.
    • (2005) Diabetes , vol.54 , pp. 3154-3160
    • Bruce, C.R.1    Mertz, V.A.2    Heigenhauser, G.J.3    Dyck, D.J.4
  • 66
    • 21344449294 scopus 로고    scopus 로고
    • Autocrine action of adiponectin on human fat cells prevents the release of insulin resistance-inducing factors
    • Dietze-Schroeder D, Sell H, Uhlig M, Koenen M, Eckel J. Autocrine action of adiponectin on human fat cells prevents the release of insulin resistance-inducing factors. Diabetes 2005;54:2003-11.
    • (2005) Diabetes , vol.54 , pp. 2003-2011
    • Dietze-Schroeder, D.1    Sell, H.2    Uhlig, M.3    Koenen, M.4    Eckel, J.5
  • 67
    • 34547403216 scopus 로고    scopus 로고
    • Redox-dependent and ligand-independent trans-activation of insulin receptor by globular adiponectin
    • Fiaschi T, Buricchi F, Cozzi G, Matthias S, Parri M, Raugei G, et al. Redox-dependent and ligand-independent trans-activation of insulin receptor by globular adiponectin. Hepatology 2007;46:130-9.
    • (2007) Hepatology , vol.46 , pp. 130-139
    • Fiaschi, T.1    Buricchi, F.2    Cozzi, G.3    Matthias, S.4    Parri, M.5    Raugei, G.6
  • 68
    • 33846331236 scopus 로고    scopus 로고
    • Differential regulation of adiponectin receptor gene expression by adiponectin and leptin in myotubes derived from obese and diabetic individuals
    • McAinch AJ, Steinberg GR, Mollica J, O'Brien PE, Dixon JB, Macaulay SL, et al. Differential regulation of adiponectin receptor gene expression by adiponectin and leptin in myotubes derived from obese and diabetic individuals. Obesity (Silver Spring) 2006;14:1898-904.
    • (2006) Obesity (Silver Spring) , vol.14 , pp. 1898-1904
    • McAinch, A.J.1    Steinberg, G.R.2    Mollica, J.3    O'Brien, P.E.4    Dixon, J.B.5    Macaulay, S.L.6
  • 69
    • 33745864810 scopus 로고    scopus 로고
    • MKR mice are resistant to the metabolic actions of both insulin and adiponectin: Discordance between insulin resistance and adiponectin responsiveness
    • Kim CH, Pennisi P, Zhao H, Yakar S, Kaufman JB, Iganaki K, et al. MKR mice are resistant to the metabolic actions of both insulin and adiponectin: discordance between insulin resistance and adiponectin responsiveness. Am J Physiol Endocrinol Metab 2006;291: E298-305.
    • (2006) Am. J. Physiol. Endocrinol. Metab. , vol.291
    • Kim, C.H.1    Pennisi, P.2    Zhao, H.3    Yakar, S.4    Kaufman, J.B.5    Iganaki, K.6
  • 70
    • 34547586298 scopus 로고    scopus 로고
    • Adiponectin resistance exacerbates insulin resistance in insulin receptor transgenic/knockout mice
    • Lin HV, Kim JY, Pocai A, Rossetti L, Shapiro L, Scherer PE, et al. Adiponectin resistance exacerbates insulin resistance in insulin receptor transgenic/knockout mice. Diabetes 2007;56:1969-76.
    • (2007) Diabetes , vol.56 , pp. 1969-1976
    • Lin, H.V.1    Kim, J.Y.2    Pocai, A.3    Rossetti, L.4    Shapiro, L.5    Scherer, P.E.6
  • 71
    • 3142701401 scopus 로고    scopus 로고
    • Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity
    • Tsuchida A, Yamauchi T, Ito Y, Hada Y, Maki T, Takekawa S, et al. Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity. J Biol Chem 2004;279:30817-22.
    • (2004) J. Biol. Chem. , vol.279 , pp. 30817-30822
    • Tsuchida, A.1    Yamauchi, T.2    Ito, Y.3    Hada, Y.4    Maki, T.5    Takekawa, S.6
  • 73
    • 4344713648 scopus 로고    scopus 로고
    • Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism
    • Staiger H, Kaltenbach S, Staiger K, Stefan N, Fritsche A, Guirguis A, et al. Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism. Diabetes 2004;53:2195-201.
    • (2004) Diabetes , vol.53 , pp. 2195-2201
    • Staiger, H.1    Kaltenbach, S.2    Staiger, K.3    Stefan, N.4    Fritsche, A.5    Guirguis, A.6
  • 74
    • 0036479251 scopus 로고    scopus 로고
    • Ceramide-induced inhibition of Akt is mediated through protein kinase Czeta: Implications for growth arrest
    • Bourbon NA, Sandirasegarane L, Kester M. Ceramide-induced inhibition of Akt is mediated through protein kinase Czeta: implications for growth arrest. J Biol Chem 2002;277:3286-92.
    • (2002) J. Biol. Chem. , vol.277 , pp. 3286-3292
    • Bourbon, N.A.1    Sandirasegarane, L.2    Kester, M.3
  • 76
    • 0029791717 scopus 로고    scopus 로고
    • Further characterization of the metabolic properties of triglyceride-rich lipoproteins from human and mouse apoC-III transgenic mice
    • Aalto-Setala K, Weinstock PH, Bisgaier CL, Wu L, Smith JD, Breslow JL. Further characterization of the metabolic properties of triglyceride-rich lipoproteins from human and mouse apoC-III transgenic mice. J Lipid Res 1996;37:1802-11.
    • (1996) J. Lipid Res. , vol.37 , pp. 1802-1811
    • Aalto-Setala, K.1    Weinstock, P.H.2    Bisgaier, C.L.3    Wu, L.4    Smith, J.D.5    Breslow, J.L.6
  • 77
    • 50349101553 scopus 로고    scopus 로고
    • Apolipoprotein CIII links hyperlipidemia with vascular endothelial cell dysfunction
    • Kawakami A, Osaka M, Tani M, Azuma H, Sacks FM, Shimokado K, et al. Apolipoprotein CIII links hyperlipidemia with vascular endothelial cell dysfunction. Circulation 2008;118:731-42.
    • (2008) Circulation , vol.118 , pp. 731-742
    • Kawakami, A.1    Osaka, M.2    Tani, M.3    Azuma, H.4    Sacks, F.M.5    Shimokado, K.6
  • 78
    • 0036224228 scopus 로고    scopus 로고
    • Lipid infusion impairs physiologic insulin-mediated capillary recruitment and muscle glucose uptake in vivo
    • Clerk LH, Rattigan S, Clark MG. Lipid infusion impairs physiologic insulin-mediated capillary recruitment and muscle glucose uptake in vivo. Diabetes 2002;51:1138-45.
    • (2002) Diabetes , vol.51 , pp. 1138-1145
    • Clerk, L.H.1    Rattigan, S.2    Clark, M.G.3
  • 79
    • 7044269441 scopus 로고    scopus 로고
    • Free fatty acid levels modulate microvascular function: Relevance for obesity-associated insulin resistance, hypertension, and microangiopathy
    • De Jongh RT, Serne EH, Ijzerman RG, De Vries G, Stehouwer CD. Free fatty acid levels modulate microvascular function: relevance for obesity-associated insulin resistance, hypertension, and microangiopathy. Diabetes 2004;53:2873-82.
    • (2004) Diabetes , vol.53 , pp. 2873-2882
    • De Jongh, R.T.1    Serne, E.H.2    Ijzerman, R.G.3    De Vries, G.4    Stehouwer, C.D.5
  • 80
    • 2942584974 scopus 로고    scopus 로고
    • ERK1/2 mediates insulin stimulation of Na+, K+-ATPase by phosphorylation of the alpha-subunit in human skeletal muscle cells
    • Al-Khalili L, Kotova O, Tsuchida H, Ehren I, Feraille E, Krook A, et al. ERK1/2 mediates insulin stimulation of Na+, K+-ATPase by phosphorylation of the alpha-subunit in human skeletal muscle cells. J Biol Chem 2004;279:25211-8.
    • (2004) J. Biol. Chem. , vol.279 , pp. 25211-25218
    • Al-Khalili, L.1    Kotova, O.2    Tsuchida, H.3    Ehren, I.4    Feraille, E.5    Krook, A.6
  • 81
    • 18544363627 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol 3-kinase enhances mitogenic actions of insulin in endothelial cells
    • Montagnani M, Golovchenko I, Kim I, Koh GY, Goalstone ML, Mundhekar AN, et al. Inhibition of phosphatidylinositol 3-kinase enhances mitogenic actions of insulin in endothelial cells. J Biol Chem 2002;277:1794-9.
    • (2002) J. Biol. Chem. , vol.277 , pp. 1794-1799
    • Montagnani, M.1    Golovchenko, I.2    Kim, I.3    Koh, G.Y.4    Goalstone, M.L.5    Mundhekar, A.N.6
  • 82
    • 33644759419 scopus 로고    scopus 로고
    • Loss of endothelial glycocalyx during acute hyperglycemia coincides with endothelial dysfunction and coagulation activation in vivo
    • Nieuwdorp M, van Haeften TW, Gouverneur MC, Mooij HL, van Lieshout MH, Levi M, et al. Loss of endothelial glycocalyx during acute hyperglycemia coincides with endothelial dysfunction and coagulation activation in vivo. Diabetes 2006;55:480-6.
    • (2006) Diabetes , vol.55 , pp. 480-486
    • Nieuwdorp, M.1    Van Haeften, T.W.2    Gouverneur, M.C.3    Mooij, H.L.4    Van Lieshout, M.H.5    Levi, M.6
  • 83
    • 0041703030 scopus 로고    scopus 로고
    • A novel role for calpains in the endothelial dysfunction of hyperglycemia
    • Stalker TJ, Skvarka CB, Scalia R. A novel role for calpains in the endothelial dysfunction of hyperglycemia. FASEB J 2003;17:1511-3.
    • (2003) FASEB J. , vol.17 , pp. 1511-1513
    • Stalker, T.J.1    Skvarka, C.B.2    Scalia, R.3
  • 84
    • 0034643340 scopus 로고    scopus 로고
    • Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
    • Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, et al. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 2000;404:787-90.
    • (2000) Nature , vol.404 , pp. 787-790
    • Nishikawa, T.1    Edelstein, D.2    Du, X.L.3    Yamagishi, S.4    Matsumura, T.5    Kaneda, Y.6
  • 85
    • 0035180299 scopus 로고    scopus 로고
    • Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modifcation at the Akt site
    • Du XL, Edelstein D, Dimmeler S, Ju Q, Sui C, Brownlee M. Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modifcation at the Akt site. J Clin Invest 2001;108:1341-8.
    • (2001) J. Clin. Invest. , vol.108 , pp. 1341-1348
    • Du, X.L.1    Edelstein, D.2    Dimmeler, S.3    Ju, Q.4    Sui, C.5    Brownlee, M.6
  • 86
    • 0036224781 scopus 로고    scopus 로고
    • Xanthine oxidase is involved in free radical production in type 1 diabetes: Protection by allopurinol
    • Desco MC, Asensi M, Marquez R, Martinez-Valls J, Vento M, Pallardo FV, et al. Xanthine oxidase is involved in free radical production in type 1 diabetes: protection by allopurinol. Diabetes 2002;51:1118-24.
    • (2002) Diabetes , vol.51 , pp. 1118-1124
    • Desco, M.C.1    Asensi, M.2    Marquez, R.3    Martinez-Valls, J.4    Vento, M.5    Pallardo, F.V.6
  • 87
    • 0036599334 scopus 로고    scopus 로고
    • Advanced glycation end products and endothelial dysfunction in type 2 diabetes
    • Tan KC, Chow WS, Ai VH, Metz C, Bucala R, Lam KS. Advanced glycation end products and endothelial dysfunction in type 2 diabetes. Diabetes Care 2002;25:1055-9.
    • (2002) Diabetes Care , vol.25 , pp. 1055-1059
    • Tan, K.C.1    Chow, W.S.2    Ai, V.H.3    Metz, C.4    Bucala, R.5    Lam, K.S.6


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