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Volumn 342, Issue 1, 2010, Pages 39-51

Differential susceptibility to epithelial-mesenchymal transition (EMT) of alveolar, bronchial and intestinal epithelial cells in vitro and the effect of angiotensin II receptor inhibition

Author keywords

Alveolar epithelium; Angiotensin II receptor; Bronchial epithelium; Cell culture; Epithelial mesenchymal transition; Fibrosis; Intestinal epithelium

Indexed keywords

ANGIOTENSIN 2 RECEPTOR; COLLAGEN TYPE 1; SMAD2 PROTEIN; SMAD3 PROTEIN; TELMISARTAN; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN; VIMENTIN;

EID: 77957705072     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00441-010-1029-x     Document Type: Article
Times cited : (40)

References (51)
  • 1
    • 34250769394 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and colorectal cancer: Gaining insights into tumor progression using LIM 1863 cells
    • 10.1159/000101300 17587805
    • RC Bates BM Pursell AM Mercurio 2007 Epithelial-mesenchymal transition and colorectal cancer: gaining insights into tumor progression using LIM 1863 cells Cells Tissues Organs 185 1-3 29 39 10.1159/000101300 17587805
    • (2007) Cells Tissues Organs , vol.185 , Issue.13 , pp. 29-39
    • Bates, R.C.1    Pursell, B.M.2    Mercurio, A.M.3
  • 3
    • 1542547460 scopus 로고    scopus 로고
    • Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity
    • 1:CAS:528:DC%2BD2cXjt1GmtrY%3D 10.1161/01.HYP.0000123072.34629.57 15007034
    • SC Benson HA Pershadsingh CI Ho A Chittiboyina P Desai M Pravenec N Qi J Wang MA Avery TW Kurtz 2004 Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity Hypertension 43 5 993 1002 1:CAS:528:DC%2BD2cXjt1GmtrY%3D 10.1161/01.HYP. 0000123072.34629.57 15007034
    • (2004) Hypertension , vol.43 , Issue.5 , pp. 993-1002
    • Benson, S.C.1    Pershadsingh, H.A.2    Ho, C.I.3    Chittiboyina, A.4    Desai, P.5    Pravenec, M.6    Qi, N.7    Wang, J.8    Avery, M.A.9    Kurtz, T.W.10
  • 4
    • 76949108858 scopus 로고    scopus 로고
    • Inflammation and epithelial to mesenchymal transition in lung transplant recipients: Role in dysregulated epithelial wound repair
    • 1:CAS:528:DC%2BC3cXkt1aht7s%3D 10.1111/j.1600-6143.2009.02953.x 20055810
    • LA Borthwick EI McIlroy MR Gorowiec M Brodlie GE Johnson C Ward JL Lordan PA Corris JA Kirby AJ Fisher 2010 Inflammation and epithelial to mesenchymal transition in lung transplant recipients: role in dysregulated epithelial wound repair Am J Transplant 10 3 498 509 1:CAS:528:DC%2BC3cXkt1aht7s%3D 10.1111/j.1600-6143.2009.02953.x 20055810
    • (2010) Am J Transplant , vol.10 , Issue.3 , pp. 498-509
    • Borthwick, L.A.1    McIlroy, E.I.2    Gorowiec, M.R.3    Brodlie, M.4    Johnson, G.E.5    Ward, C.6    Lordan, J.L.7    Corris, P.A.8    Kirby, J.A.9    Fisher, A.J.10
  • 5
    • 3142742249 scopus 로고    scopus 로고
    • Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro
    • 1:CAS:528:DC%2BD2cXjslynu7g%3D 10.1186/bcr778 15084245
    • KA Brown ME Aakre AE Gorska JO Price SE Eltom JA Pietenpol HL Moses 2004 Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro Breast Cancer Res 6 3 R215 R231 1:CAS:528:DC%2BD2cXjslynu7g%3D 10.1186/bcr778 15084245
    • (2004) Breast Cancer Res , vol.6 , Issue.3
    • Brown, K.A.1    Aakre, M.E.2    Gorska, A.E.3    Price, J.O.4    Eltom, S.E.5    Pietenpol, J.A.6    Moses, H.L.7
  • 6
    • 34250733867 scopus 로고    scopus 로고
    • The role of tubular epithelial-mesenchymal transition in progressive kidney disease
    • 1:CAS:528:DC%2BD2sXmvFSnu7s%3D 10.1159/000101323 17587828
    • WC Burns P Kantharidis MC Thomas 2007 The role of tubular epithelial-mesenchymal transition in progressive kidney disease Cells Tissues Organs 185 1-3 222 231 1:CAS:528:DC%2BD2sXmvFSnu7s%3D 10.1159/000101323 17587828
    • (2007) Cells Tissues Organs , vol.185 , Issue.13 , pp. 222-231
    • Burns, W.C.1    Kantharidis, P.2    Thomas, M.C.3
  • 7
    • 77954863900 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in primary human bronchial epithelial cells is Smad-dependent and enhanced by fibronectin and TNF-alpha
    • 10.1186/1755-1536-3-2 20051102
    • J Câmara G Jarai 2010 Epithelial-mesenchymal transition in primary human bronchial epithelial cells is Smad-dependent and enhanced by fibronectin and TNF-alpha Fibrogenesis Tissue Repair 3 1 2 10.1186/1755-1536-3-2 20051102
    • (2010) Fibrogenesis Tissue Repair , vol.3 , Issue.1 , pp. 2
    • Câmara, J.1    Jarai, G.2
  • 8
    • 73149101056 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transitions in the liver
    • 1:CAS:528:DC%2BD1MXhs1SjurnO 10.1002/hep.23196 19824076
    • SS Choi AM Diehl 2009 Epithelial-to-mesenchymal transitions in the liver Hepatology 50 6 2007 2013 1:CAS:528:DC%2BD1MXhs1SjurnO 10.1002/hep.23196 19824076
    • (2009) Hepatology , vol.50 , Issue.6 , pp. 2007-2013
    • Choi, S.S.1    Diehl, A.M.2
  • 9
    • 73949090678 scopus 로고    scopus 로고
    • TGF-beta1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1beta but not abrogated by corticosteroids
    • 10.1186/1465-9921-10-100 19857272
    • AM Doerner BL Zuraw 2009 TGF-beta1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1beta but not abrogated by corticosteroids Respir Res 10 100 10.1186/1465-9921-10-100 19857272
    • (2009) Respir Res , vol.10 , pp. 100
    • Doerner, A.M.1    Zuraw, B.L.2
  • 10
    • 0035872426 scopus 로고    scopus 로고
    • Transforming growth factor beta1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal-regulated kinase 2 activation
    • 1:CAS:528:DC%2BD3MXktVWqtLo%3D 11358848
    • V Ellenrieder SF Hendler W Boeck T Seufferlein A Menke C Ruhland G Adler TM Gress 2001 Transforming growth factor beta1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal-regulated kinase 2 activation Cancer Res 61 4222 4228 1:CAS:528:DC%2BD3MXktVWqtLo%3D 11358848
    • (2001) Cancer Res , vol.61 , pp. 4222-4228
    • Ellenrieder, V.1    Hendler, S.F.2    Boeck, W.3    Seufferlein, T.4    Menke, A.5    Ruhland, C.6    Adler, G.7    Gress, T.M.8
  • 11
    • 65649092106 scopus 로고    scopus 로고
    • Recent advances in molecular targets and treatment of idiopathic pulmonary fibrosis: Focus on TGFbeta signaling and the myofibroblast
    • 1:CAS:528:DC%2BD1MXltVeqtr8%3D 10.2174/092986709787846497 19355895
    • M Gharaee-Kermani B Hu SH Phan MR Gyetko 2009 Recent advances in molecular targets and treatment of idiopathic pulmonary fibrosis: focus on TGFbeta signaling and the myofibroblast Curr Med Chem 16 11 1400 1417 1:CAS:528:DC%2BD1MXltVeqtr8%3D 10.2174/092986709787846497 19355895
    • (2009) Curr Med Chem , vol.16 , Issue.11 , pp. 1400-1417
    • Gharaee-Kermani, M.1    Hu, B.2    Phan, S.H.3    Gyetko, M.R.4
  • 12
    • 0043172396 scopus 로고    scopus 로고
    • Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis
    • 10.1038/nrm1175 12923528
    • S Grünert M Jechlinger H Beug 2003 Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis Nat Rev Mol Cell Biol 4 8 657 665 10.1038/nrm1175 12923528
    • (2003) Nat Rev Mol Cell Biol , vol.4 , Issue.8 , pp. 657-665
    • Grünert, S.1    Jechlinger, M.2    Beug, H.3
  • 13
    • 69949124749 scopus 로고    scopus 로고
    • Direct contribution to organ fibrosis: Epithelial-mesenchymal transition
    • 1:CAS:528:DC%2BD1MXhtFamsb%2FF 10.1016/j.humpath.2009.02.020 19695676
    • M Guarino A Tosoni M Nebuloni 2009 Direct contribution to organ fibrosis: epithelial-mesenchymal transition Hum Pathol 40 10 1365 1376 1:CAS:528:DC%2BD1MXhtFamsb%2FF 10.1016/j.humpath.2009.02.020 19695676
    • (2009) Hum Pathol , vol.40 , Issue.10 , pp. 1365-1376
    • Guarino, M.1    Tosoni, A.2    Nebuloni, M.3
  • 14
    • 73949108120 scopus 로고    scopus 로고
    • House dust mite-promoted epithelial-to-mesenchymal transition in human bronchial epithelium
    • 1:CAS:528:DC%2BC3cXksFSjsA%3D%3D 10.1165/rcmb.2008-0449OC 19372245
    • IH Heijink DS Postma JA Noordhoek M Broekema A Kapus 2010 House dust mite-promoted epithelial-to-mesenchymal transition in human bronchial epithelium Am J Respir Cell Mol Biol 42 1 69 79 1:CAS:528:DC%2BC3cXksFSjsA%3D%3D 10.1165/rcmb.2008-0449OC 19372245
    • (2010) Am J Respir Cell Mol Biol , vol.42 , Issue.1 , pp. 69-79
    • Heijink, I.H.1    Postma, D.S.2    Noordhoek, J.A.3    Broekema, M.4    Kapus, A.5
  • 15
    • 34447309766 scopus 로고    scopus 로고
    • The myofibroblast: One function, multiple origins
    • 1:CAS:528:DC%2BD2sXntlOhtrk%3D 10.2353/ajpath.2007.070112 17525249
    • B Hinz SH Phan VJ Thannickal A Galli ML Bochaton-Piallat G Gabbiani 2007 The myofibroblast: one function, multiple origins Am J Pathol 170 6 1807 1816 1:CAS:528:DC%2BD2sXntlOhtrk%3D 10.2353/ajpath.2007.070112 17525249
    • (2007) Am J Pathol , vol.170 , Issue.6 , pp. 1807-1816
    • Hinz, B.1    Phan, S.H.2    Thannickal, V.J.3    Galli, A.4    Bochaton-Piallat, M.L.5    Gabbiani, G.6
  • 16
    • 63349086347 scopus 로고    scopus 로고
    • Posttransplant bronchiolitis obliterans syndrome is associated with bronchial epithelial to mesenchymal transition
    • 1:STN:280:DC%2BD1M3lvVygug%3D%3D 10.1111/j.1600-6143.2009.02558.x 19344464
    • S Hodge M Holmes B Banerjee M Musk A Kicic G Waterer PN Reynolds G Hodge DC Chambers 2009 Posttransplant bronchiolitis obliterans syndrome is associated with bronchial epithelial to mesenchymal transition Am J Transplant 9 4 727 733 1:STN:280:DC%2BD1M3lvVygug%3D%3D 10.1111/j.1600-6143.2009.02558.x 19344464
    • (2009) Am J Transplant , vol.9 , Issue.4 , pp. 727-733
    • Hodge, S.1    Holmes, M.2    Banerjee, B.3    Musk, M.4    Kicic, A.5    Waterer, G.6    Reynolds, P.N.7    Hodge, G.8    Chambers, D.C.9
  • 18
    • 0346724511 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and its implications for fibrosis
    • 1:CAS:528:DC%2BD3sXhtVSmtLrL 14679171
    • R Kalluri EG Neilson 2003 Epithelial-mesenchymal transition and its implications for fibrosis J Clin Invest 112 1776 1784 1:CAS:528: DC%2BD3sXhtVSmtLrL 14679171
    • (2003) J Clin Invest , vol.112 , pp. 1776-1784
    • Kalluri, R.1    Neilson, E.G.2
  • 19
    • 26244458018 scopus 로고    scopus 로고
    • TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT)
    • 10.1186/1465-9921-6-56 15946381
    • H Kasai JT Allen RM Mason T Kamimura Z Zhang 2005 TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT) Respir Res 6 56 10.1186/1465-9921-6-56 15946381
    • (2005) Respir Res , vol.6 , pp. 56
    • Kasai, H.1    Allen, J.T.2    Mason, R.M.3    Kamimura, T.4    Zhang, Z.5
  • 20
    • 33748375828 scopus 로고    scopus 로고
    • Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix
    • 1:CAS:528:DC%2BD28Xptlels74%3D 10.1073/pnas.0605669103 16924102
    • KK Kim MC Kugler PJ Wolters L Robillard MG Galvez AN Brumwell D Sheppard HA Chapman 2006 Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix Proc Natl Acad Sci USA 103 13180 13185 1:CAS:528:DC%2BD28Xptlels74%3D 10.1073/pnas.0605669103 16924102
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 13180-13185
    • Kim, K.K.1    Kugler, M.C.2    Wolters, P.J.3    Robillard, L.4    Galvez, M.G.5    Brumwell, A.N.6    Sheppard, D.7    Chapman, H.A.8
  • 21
    • 73649111336 scopus 로고    scopus 로고
    • The effect of Telmisartan on collagen biosynthesis depends on the status of estrogen activation in breast cancer cells
    • 1:CAS:528:DC%2BC3cXnvFyitg%3D%3D 10.1016/j.ejphar.2009.11.043 19945454
    • B Kociecka A Surazynski W Miltyk J Palka 2010 The effect of Telmisartan on collagen biosynthesis depends on the status of estrogen activation in breast cancer cells Eur J Pharmacol 628 1-3 51 56 1:CAS:528:DC%2BC3cXnvFyitg%3D%3D 10.1016/j.ejphar.2009.11.043 19945454
    • (2010) Eur J Pharmacol , vol.628 , Issue.13 , pp. 51-56
    • Kociecka, B.1    Surazynski, A.2    Miltyk, W.3    Palka, J.4
  • 22
    • 69049103163 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition induced by transforming growth factor-beta1 in mouse tracheal epithelial cells
    • 10.1111/j.1440-1843.2009.01561.x 19659836
    • S Kuroishi T Suda T Fujisawa K Ide N Inui Y Nakamura H Nakamura K Chida 2009 Epithelial-mesenchymal transition induced by transforming growth factor-beta1 in mouse tracheal epithelial cells Respirology 14 6 828 837 10.1111/j.1440-1843.2009.01561.x 19659836
    • (2009) Respirology , vol.14 , Issue.6 , pp. 828-837
    • Kuroishi, S.1    Suda, T.2    Fujisawa, T.3    Ide, K.4    Inui, N.5    Nakamura, Y.6    Nakamura, H.7    Chida, K.8
  • 23
    • 16444377075 scopus 로고    scopus 로고
    • Interleukin-1β causes pulmonary inflammation, emphysema, and airway remodeling in the adult murine lung
    • 1:CAS:528:DC%2BD2MXivFGltro%3D 10.1165/rcmb.2004-0309OC 15668323
    • U Lappalainen JA Whitsett SE Wert JW Tichelaar K Bry 2005 Interleukin-1β causes pulmonary inflammation, emphysema, and airway remodeling in the adult murine lung Am J Respir Cell Mol Biol 32 311 318 1:CAS:528:DC%2BD2MXivFGltro%3D 10.1165/rcmb.2004-0309OC 15668323
    • (2005) Am J Respir Cell Mol Biol , vol.32 , pp. 311-318
    • Lappalainen, U.1    Whitsett, J.A.2    Wert, S.E.3    Tichelaar, J.W.4    Bry, K.5
  • 24
    • 0031943230 scopus 로고    scopus 로고
    • Evidence that Calu-3 human airway cells secrete bicarbonate
    • 1:CAS:528:DyaK1cXitVCrtL4%3D 9530182
    • MC Lee CM Penland JH Widdicombe JJ Wine 1998 Evidence that Calu-3 human airway cells secrete bicarbonate Am J Physiol 274 3 Pt 1 L450 L453 1:CAS:528:DyaK1cXitVCrtL4%3D 9530182
    • (1998) Am J Physiol , vol.274 , Issue.3 PART 1
    • Lee, M.C.1    Penland, C.M.2    Widdicombe, J.H.3    Wine, J.J.4
  • 25
    • 57349194661 scopus 로고    scopus 로고
    • Inflammatory cytokines augments TGF-beta1-induced epithelial-mesenchymal transition in A549 cells by up-regulating TbetaR-I
    • 1:CAS:528:DC%2BD1MXlvF2ntQ%3D%3D 10.1002/cm.20315 18792103
    • X Liu 2008 Inflammatory cytokines augments TGF-beta1-induced epithelial-mesenchymal transition in A549 cells by up-regulating TbetaR-I Cell Motil Cytoskeleton 65 12 935 944 1:CAS:528:DC%2BD1MXlvF2ntQ%3D%3D 10.1002/cm.20315 18792103
    • (2008) Cell Motil Cytoskeleton , vol.65 , Issue.12 , pp. 935-944
    • Liu, X.1
  • 26
    • 73449133329 scopus 로고    scopus 로고
    • AGEs increased migration and inflammatory responses of adventitial fibroblasts via RAGE, MAPK and NF-kappaB pathways
    • 1:CAS:528:DC%2BC3cXkt1ChtQ%3D%3D 10.1016/j.atherosclerosis.2009.06.007 19959167
    • Y Liu C Liang X Liu B Liao X Pan Y Ren M Fan M Li Z He J Wu Z Wu 2010 AGEs increased migration and inflammatory responses of adventitial fibroblasts via RAGE, MAPK and NF-kappaB pathways Atherosclerosis 208 1 34 42 1:CAS:528:DC%2BC3cXkt1ChtQ%3D%3D 10.1016/j.atherosclerosis.2009.06.007 19959167
    • (2010) Atherosclerosis , vol.208 , Issue.1 , pp. 34-42
    • Liu, Y.1    Liang, C.2    Liu, X.3    Liao, B.4    Pan, X.5    Ren, Y.6    Fan, M.7    Li, M.8    He, Z.9    Wu, J.10    Wu, Z.11
  • 28
    • 77951996610 scopus 로고    scopus 로고
    • Combination of aspirin with telmisartan suppress the augmented TGF-beta/smad signaling during the development of streptozotocin induced type i diabetic nephropathy
    • 1:CAS:528:DC%2BC3cXkvFemsL4%3D 10.1016/j.cbi.2010.03.008 20223228
    • SR Mulay AB Gaikwad K Tikoo 2010 Combination of aspirin with telmisartan suppress the augmented TGF-beta/smad signaling during the development of streptozotocin induced type I diabetic nephropathy Chem Biol Interact 185 2 137 142 1:CAS:528:DC%2BC3cXkvFemsL4%3D 10.1016/j.cbi.2010.03.008 20223228
    • (2010) Chem Biol Interact , vol.185 , Issue.2 , pp. 137-142
    • Mulay, S.R.1    Gaikwad, A.B.2    Tikoo, K.3
  • 29
    • 0037353255 scopus 로고    scopus 로고
    • Pulmonary fibrosis: Cellular and molecular events
    • 1:CAS:528:DC%2BD3sXjtl2ms7o%3D 10.1046/j.1440-1827.2003.01446.x 12608894
    • MS Razzaque T Taguchi 2003 Pulmonary fibrosis: cellular and molecular events Pathol Int 53 3 133 145 1:CAS:528:DC%2BD3sXjtl2ms7o%3D 10.1046/j.1440-1827.2003.01446.x 12608894
    • (2003) Pathol Int , vol.53 , Issue.3 , pp. 133-145
    • Razzaque, M.S.1    Taguchi, T.2
  • 30
    • 67649888821 scopus 로고    scopus 로고
    • Intestinal fibrosis in IBD-a dynamic, multifactorial process
    • 1:CAS:528:DC%2BD1MXmsFWmur0%3D 10.1038/nrgastro.2009.31 19347014
    • F Rieder C Fiocchi 2009 Intestinal fibrosis in IBD-a dynamic, multifactorial process Nat Rev Gastroenterol Hepatol 6 4 228 235 1:CAS:528:DC%2BD1MXmsFWmur0%3D 10.1038/nrgastro.2009.31 19347014
    • (2009) Nat Rev Gastroenterol Hepatol , vol.6 , Issue.4 , pp. 228-235
    • Rieder, F.1    Fiocchi, C.2
  • 31
    • 70350507784 scopus 로고    scopus 로고
    • Are the pleiotropic effects of telmisartan clinically relevant?
    • 1:CAS:528:DC%2BD1MXpvVyktbk%3D 10.2174/138161209788923859 19689352
    • CV Rizos MS Elisaf EN Liberopoulos 2009 Are the pleiotropic effects of telmisartan clinically relevant? Curr Pharm Des 15 24 2815 2832 1:CAS:528:DC%2BD1MXpvVyktbk%3D 10.2174/138161209788923859 19689352
    • (2009) Curr Pharm des , vol.15 , Issue.24 , pp. 2815-2832
    • Rizos, C.V.1    Elisaf, M.S.2    Liberopoulos, E.N.3
  • 33
    • 39449095723 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype
    • 10.1158/0008-5472.CAN-07-2017 18281472
    • D Sarrió SM Rodriguez-Pinilla D Hardisson A Cano G Moreno-Bueno J Palacios 2008 Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype Cancer Res 68 4 989 997 10.1158/0008-5472.CAN-07-2017 18281472
    • (2008) Cancer Res , vol.68 , Issue.4 , pp. 989-997
    • Sarrió, D.1    Rodriguez-Pinilla, S.M.2    Hardisson, D.3    Cano, A.4    Moreno-Bueno, G.5    Palacios, J.6
  • 34
    • 0034798707 scopus 로고    scopus 로고
    • Leaving the neighborhood: Molecular mechanisms involved during epithelial-mesenchymal transition
    • 1:CAS:528:DC%2BD3MXptVOjsL4%3D 10.1002/bies.1132 11598958
    • P Savagner 2001 Leaving the neighborhood: molecular mechanisms involved during epithelial-mesenchymal transition Bioessays 23 912 923 1:CAS:528:DC%2BD3MXptVOjsL4%3D 10.1002/bies.1132 11598958
    • (2001) Bioessays , vol.23 , pp. 912-923
    • Savagner, P.1
  • 35
    • 25444478849 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: An epithelial/fibroblastic cross-talk disorder
    • 10.1186/rr175 11806838
    • M Selman A Pardo 2002 Idiopathic pulmonary fibrosis: an epithelial/fibroblastic cross-talk disorder Respir Res 3 3 10.1186/rr175 11806838
    • (2002) Respir Res , vol.3 , pp. 3
    • Selman, M.1    Pardo, A.2
  • 36
    • 0028307695 scopus 로고
    • Calu-3: A human airway epithelial cell line that shows cAMP-dependent Cl- secretion
    • 1:CAS:528:DyaK2cXktlWqt7g%3D 7515578
    • BQ Shen WE Finkbeiner JJ Wine RJ Mrsny JH Widdicombe 1994 Calu-3: a human airway epithelial cell line that shows cAMP-dependent Cl- secretion Am J Physiol 266 5 Pt 1 L493 L501 1:CAS:528:DyaK2cXktlWqt7g%3D 7515578
    • (1994) Am J Physiol , vol.266 , Issue.5 PART 1
    • Shen, B.Q.1    Finkbeiner, W.E.2    Wine, J.J.3    Mrsny, R.J.4    Widdicombe, J.H.5
  • 37
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • 1:CAS:528:DC%2BD28XhtlWltLg%3D 10.1038/nrm1835 16493418
    • JP Thiery JP Sleeman 2006 Complex networks orchestrate epithelial-mesenchymal transitions Nat Rev Mol Cell Biol 7 2 131 142 1:CAS:528:DC%2BD28XhtlWltLg%3D 10.1038/nrm1835 16493418
    • (2006) Nat Rev Mol Cell Biol , vol.7 , Issue.2 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 38
    • 34248355179 scopus 로고    scopus 로고
    • Angiotensin-TGF-beta 1 crosstalk in human idiopathic pulmonary fibrosis: Autocrine mechanisms in myofibroblasts and macrophages
    • 1:CAS:528:DC%2BD2sXmsFehsrY%3D 10.2174/138161207780618885 17504233
    • BD Uhal JK Kim X Li M Molina-Molina 2007 Angiotensin-TGF-beta 1 crosstalk in human idiopathic pulmonary fibrosis: autocrine mechanisms in myofibroblasts and macrophages Curr Pharm Des 13 12 1247 1256 1:CAS:528:DC%2BD2sXmsFehsrY%3D 10.2174/138161207780618885 17504233
    • (2007) Curr Pharm des , vol.13 , Issue.12 , pp. 1247-1256
    • Uhal, B.D.1    Kim, J.K.2    Li, X.3    Molina-Molina, M.4
  • 41
    • 34548411746 scopus 로고    scopus 로고
    • TGF-beta-induced EMT: Mechanisms and implications for fibrotic lung disease
    • 1:CAS:528:DC%2BD2sXhtVOqsbjP 10.1152/ajplung.00163.2007 17631612
    • BC Willis Z Borok 2007 TGF-beta-induced EMT: mechanisms and implications for fibrotic lung disease Am J Physiol Lung Cell Mol Physiol 293 L525 L534 1:CAS:528:DC%2BD2sXhtVOqsbjP 10.1152/ajplung.00163.2007 17631612
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.293
    • Willis, B.C.1    Borok, Z.2
  • 42
    • 17844384822 scopus 로고    scopus 로고
    • Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: Potential role in idiopathic pulmonary fibrosis
    • 1:CAS:528:DC%2BD2MXksFGmtL8%3D 15855634
    • BC Willis JM Liebler K Luby-Phelps AG Nicholson ED Crandall RM du Bois Z Borok 2005 Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis Am J Pathol 166 1321 1332 1:CAS:528:DC%2BD2MXksFGmtL8%3D 15855634
    • (2005) Am J Pathol , vol.166 , pp. 1321-1332
    • Willis, B.C.1    Liebler, J.M.2    Luby-Phelps, K.3    Nicholson, A.G.4    Crandall, E.D.5    Du Bois, R.M.6    Borok, Z.7
  • 43
    • 33744944779 scopus 로고    scopus 로고
    • Epithelial origin of myofibroblasts during fibrosis in the lung
    • 1:CAS:528:DC%2BD28XmtVOktro%3D 10.1513/pats.200601-004TK 16738204
    • BC Willis RM duBois Z Borok 2006 Epithelial origin of myofibroblasts during fibrosis in the lung Proc Am Thorac Soc 3 377 382 1:CAS:528: DC%2BD28XmtVOktro%3D 10.1513/pats.200601-004TK 16738204
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 377-382
    • Willis, B.C.1    Dubois, R.M.2    Borok, Z.3
  • 44
    • 0041677660 scopus 로고    scopus 로고
    • Release of biologically active TGF-beta1 by alveolar epithelial cells results in pulmonary fibrosis
    • 1:CAS:528:DC%2BD3sXnsVGmu7k%3D 12598227
    • YD Xu J Hua A Mui R O'Connor G Grotendorst N Khalil 2003 Release of biologically active TGF-beta1 by alveolar epithelial cells results in pulmonary fibrosis Am J Physiol Lung Cell Mol Physiol 285 3 L527 L539 1:CAS:528: DC%2BD3sXnsVGmu7k%3D 12598227
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.285 , Issue.3
    • Xu, Y.D.1    Hua, J.2    Mui, A.3    O'Connor, R.4    Grotendorst, G.5    Khalil, N.6
  • 45
    • 59449090107 scopus 로고    scopus 로고
    • TGF-beta-induced epithelial to mesenchymal transition
    • 1:CAS:528:DC%2BD1MXht1amsL4%3D 10.1038/cr.2009.5 19153598
    • J Xu S Lamouille R Derynck 2009 TGF-beta-induced epithelial to mesenchymal transition Cell Res 19 2 156 172 1:CAS:528:DC%2BD1MXht1amsL4%3D 10.1038/cr.2009.5 19153598
    • (2009) Cell Res , vol.19 , Issue.2 , pp. 156-172
    • Xu, J.1    Lamouille, S.2    Derynck, R.3
  • 46
    • 6344254484 scopus 로고    scopus 로고
    • TGF-beta1 induces alveolar epithelial to mesenchymal transition in vitro
    • 1:CAS:528:DC%2BD2cXovVKqsr4%3D 10.1016/j.lfs.2004.06.019 15501477
    • HW Yao QM Xie JQ Chen YM Deng HF Tang 2004 TGF-beta1 induces alveolar epithelial to mesenchymal transition in vitro Life Sci 76 1 29 37 1:CAS:528:DC%2BD2cXovVKqsr4%3D 10.1016/j.lfs.2004.06.019 15501477
    • (2004) Life Sci , vol.76 , Issue.1 , pp. 29-37
    • Yao, H.W.1    Xie, Q.M.2    Chen, J.Q.3    Deng, Y.M.4    Tang, H.F.5
  • 47
    • 33645216539 scopus 로고    scopus 로고
    • Losartan attenuates bleomycin-induced pulmonary fibrosis in rats
    • 1:CAS:528:DC%2BD28Xis1eqtrg%3D 16330873
    • HW Yao JP Zhu MH Zhao Y Lu 2006 Losartan attenuates bleomycin-induced pulmonary fibrosis in rats Respiration 73 2 236 242 1:CAS:528: DC%2BD28Xis1eqtrg%3D 16330873
    • (2006) Respiration , vol.73 , Issue.2 , pp. 236-242
    • Yao, H.W.1    Zhu, J.P.2    Zhao, M.H.3    Lu, Y.4
  • 48
    • 35748953774 scopus 로고    scopus 로고
    • A combination of a PPAR-gamma agonist and an angiotensin II receptor blocker attenuates proinflammatory signaling and stimulates expression of Smad7 in human peritoneal mesothelial cells
    • 1:CAS:528:DC%2BD2sXhsVGisr7M 18044261
    • Q Yao ER Ayala JQ Qian P Stenvinkel J Axelsson B Lindholm 2007 A combination of a PPAR-gamma agonist and an angiotensin II receptor blocker attenuates proinflammatory signaling and stimulates expression of Smad7 in human peritoneal mesothelial cells Clin Nephrol 68 5 295 301 1:CAS:528: DC%2BD2sXhsVGisr7M 18044261
    • (2007) Clin Nephrol , vol.68 , Issue.5 , pp. 295-301
    • Yao, Q.1    Ayala, E.R.2    Qian, J.Q.3    Stenvinkel, P.4    Axelsson, J.5    Lindholm, B.6
  • 49
    • 58449137236 scopus 로고    scopus 로고
    • Telmisartan but not valsartan inhibits TGF-beta-mediated accumulation of extracellular matrix via activation of PPARgamma
    • 1:CAS:528:DC%2BD1cXhtlyrsLvO 10.1007/s11596-008-0512-z 18846335
    • Y Yao R Zou X Liu J Jiang Q Huang Y He M Li S Wang J Zhou D Ma G Xu 2008 Telmisartan but not valsartan inhibits TGF-beta-mediated accumulation of extracellular matrix via activation of PPARgamma J Huazhong Univ Sci Technolog Med Sci 28 5 543 548 1:CAS:528:DC%2BD1cXhtlyrsLvO 10.1007/s11596-008-0512-z 18846335
    • (2008) J Huazhong Univ Sci Technolog Med Sci , vol.28 , Issue.5 , pp. 543-548
    • Yao, Y.1    Zou, R.2    Liu, X.3    Jiang, J.4    Huang, Q.5    He, Y.6    Li, M.7    Wang, S.8    Zhou, J.9    Ma, D.10    Xu, G.11
  • 50
    • 67349130377 scopus 로고    scopus 로고
    • TGF-beta1 induces human bronchial epithelial cell-to-mesenchymal transition in vitro
    • 1:CAS:528:DC%2BD1MXlvFyisLs%3D 10.1007/s00408-009-9139-5 19252942
    • M Zhang Z Zhang HY Pan DX Wang ZT Deng XL Ye 2009 TGF-beta1 induces human bronchial epithelial cell-to-mesenchymal transition in vitro Lung 187 3 187 194 1:CAS:528:DC%2BD1MXlvFyisLs%3D 10.1007/s00408-009-9139-5 19252942
    • (2009) Lung , vol.187 , Issue.3 , pp. 187-194
    • Zhang, M.1    Zhang, Z.2    Pan, H.Y.3    Wang, D.X.4    Deng, Z.T.5    Ye, X.L.6
  • 51
    • 0032770014 scopus 로고    scopus 로고
    • Cytokine-induced airway epithelial ICAM-1 upregulation: Quantification by high-resolution scanning and transmission electron microscopy
    • 1:STN:280:DyaK1Mznt1Okuw%3D%3D 10.1183/09031936.99.13613299 10445607
    • J Zhu AV Rogers A Burke-Gaffney PG Hellewell PK Jeffery 1999 Cytokine-induced airway epithelial ICAM-1 upregulation: quantification by high-resolution scanning and transmission electron microscopy Eur Respir J 13 6 1318 1328 1:STN:280:DyaK1Mznt1Okuw%3D%3D 10.1183/09031936.99.13613299 10445607
    • (1999) Eur Respir J , vol.13 , Issue.6 , pp. 1318-1328
    • Zhu, J.1    Rogers, A.V.2    Burke-Gaffney, A.3    Hellewell, P.G.4    Jeffery, P.K.5


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