Pharmacological modulation of epithelial mesenchymal transition caused by angiotensin II. Role of ROCK and MAPK pathways

Pharmaceutical Research

Volumn 25, Issue 10, 2008, Pages 2447-2461

  Rodrigues Díez, Raquel ^a   Carvajal González, Gisselle ^b   Sánchez López, Elsa ^a   Rodríguez Vita, Juan ^a   Rodrigues Díez, Raúl ^a   Selgas, Rafael ^c   Ortiz, Alberto ^d   Egido, Jesús ^d   Mezzano, Sergio ^b   Ruiz Ortega, Marta ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b UNIVERSIDAD AUSTRAL DE CHILE   (Chile)

^c HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^d Hospital UniversitarioFundación Jiménez Díaz   (Spain)

Author keywords

Angiotensin; Epithelial mesenchymal transition; Kinase inhibitors; Renal damage; Statins

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALPHA SMOOTH MUSCLE ACTIN; ANGIOTENSIN II; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ATORVASTATIN; CONNECTIVE TISSUE GROWTH FACTOR; FASUDIL; MITOGEN ACTIVATED PROTEIN KINASE 14; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SIMVASTATIN; UVOMORULIN; VIMENTIN;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG EFFECT; DRUG TARGETING; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; KIDNEY FIBROSIS; KIDNEY TUBULE CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANGIOTENSIN II; CELL LINE; CELL TRANSDIFFERENTIATION; EPITHELIAL CELLS; FIBROSIS; HEPTANOIC ACIDS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; IMMEDIATE-EARLY PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY TUBULES, PROXIMAL; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PHENOTYPE; PROTEIN KINASE INHIBITORS; PYRROLES; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; SIMVASTATIN; TIME FACTORS; TRANSFECTION;

EID: 51649100175     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-008-9636-x     Document Type: Article

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