The beta-glucan receptor dectin-1 recognizes specific morphologies of aspergillus fumigatus

PLoS Pathogens

Volumn 1, Issue 4, 2005, Pages 0323-0334

  Steele, Chad ^a   Rapaka, Rekha R ^a   Metz, Allison ^a   Pop, Shannon M ^a   Williams, David L ^b   Gordon, Siamon ^c   Kolls, Jay K ^a   Brown, Gordon D ^d  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b East Tennessee State University   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CYTOKINE; DECTIN 1; FUNGAL PROTEIN; MEMBRANE PROTEIN; NERVE PROTEIN;

ARTICLE; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; HUMAN; IMMUNOLOGY; INFLAMMATION; LUNG ALVEOLUS MACROPHAGE;

ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CHEMOKINES; CYTOKINES; FUNGAL PROTEINS; HUMANS; INFLAMMATION; MACROPHAGES, ALVEOLAR; MEMBRANE PROTEINS; NERVE TISSUE PROTEINS;

EID: 37349107599     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.0010042     Document Type: Article

References (43)

1. Kontoyiannis DP, Bodey GP (2002) Invasive aspergillosis in 2002: An update. Eur J Clin Microbiol Infect Dis 21: 161-172.
2. Baddley JW, Stroud TP, Salzman D, Pappas PG (2001) Invasive mold infections in allogeneic bone marrow transplant recipients. Clin Infect Dis 32: 1319-1324.
3. Denning DW (1998) Invasive aspergillosis. Clin Infect Dis 26: 781-803.
4. Patterson TF, Kirkpatrick WR, White M, Hiemenz JW, Wingard JR, et al. (2000) Invasive aspergillosis. Disease spectrum, treatment practices, and outcomes. I3 Aspergillus Study Group. Medicine 79: 250-260.
5. Marr KA, Patterson T, Denning D (2002) Aspergillosis pathogenesis, clinical manifestations and therapy. Infect Dis Clin North Am 16: 875-894.
6. Singh N (2003) Fungal infections in the recipients of solid organ transplantation. Infect Dis Clin North Am 17: 113-134.
7. Stevens DA, Moss RB, Kurup VP, Knutsen AP, Greenberger P, et al. (2003) Allergic bronchopulmonary aspergillosis in cystic fibrosis - state of the art: Cystic Fibrosis Foundation Consensus Conference. Clin Infect Dis 37: S225-S264.
8. Romani L (2004) Immunity to fungal infections. Nat Rev Immunol 4: 1-23.
9. Schaffner A, Douglas H, Braude A (1982) Selective protection against conidia by mononuclear and against mycelia by polymorphonuclear phagocytes in resistance to Aspergillus. Observations on these two lines of defense in vivo and in vitro with human and mouse phagocytes. J Clin Invest 69: 617-631.
10. Mambula SS, Sau K, Henneke P, Golenbock DT, Levitz SM (2002) Toll-like receptor (TLR) signaling in response to Aspergillus fumigatus. J Biol Chem 277: 39320-39326.
11. Meier A, Kirschning CJ, Nikolaus T, Wagner H, Heesemann J, et al. (2003) Toll-like receptor (TLR) 2 and TLR4 are essential for Aspergillus-induced activation of murine macrophages. Cellular Microbiol 5: 561-570.
12. Wang JE, Warris A, Ellingsen EA, Jorgensen PF, Flo TH, et al. (2001) Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae. Infect Immun 69: 2402-2406.
13. Bellocchio S, Montagnoli C, Bozza S, Gaziano R, Rossi G, et al. (2004) The contribution of toll-like/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo. J Immunol 172: 3059-3069.
14. Netea MG, Warris A, Van der Meer JWM, Fenton MJ, Verver-Janssen TJG, et al. (2003) Aspergillus fumigatus evades immune recognition during germination through loss of toll-like receptor-4-mediated signal transduction. J Infect Dis 188: 320-326.
15. Marr KA, Balajee SA, Hawn TR, Ozinsky A, Pham U, et al. (2003) Differential role of MyD88 in macrophage-mediated responses to opportunistic fungal pathogens. Infect Immun 71: 5280-5286. (Pubitemid 37070775)
16. Bellocchio S, Moretti S, Perruccio K, Fallarino F, Bozza S, et al. (2004) TLR2 govern neutrophil activity in aspergillosis. J Immunol 173: 7406-7415. (Pubitemid 39628180)
17. Overland G, Stuestol JF, Dahle MK, Myhre AE, Netea MG, et al. (2005) Cytokine responses to fungal pathogens in Kupffer cells are Toll-like receptor 4 independent and mediated by tyrosine kinases. Scand J Immunol 62: 148-154. (Pubitemid 41176497)
18. Beauvais A, Latge JP (2001) Membrane and cell wall targets in Aspergillus fumigatus. Drug Resist Updat 4: 38-49. (Pubitemid 32267824)
19. Persat F, Noirrey N, Diana J, Gariazzo MJ, Schmitt D, et al. (2003) Binding of live conidia of Aspergillus fumigatus activates in vitro-generated human Langerhans cells via a lectin of galactomannan specificity. Clin Exp Immunol 133: 370-377. (Pubitemid 37046961)
20. Serrano-Gomez D, Dominguez-Soto A, Ancochea J, Jimenez-Heffernan JA, Leal JA, et al. (2004) Dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin mediates binding and internalization of Aspergillus fumigatus conidia by dendritic cells and macrophages. J Immunol 173: 5635-5643. (Pubitemid 39392151)
21. Bozza S, Gaziano R, Spreca A, Bacci A, Montagnoli C, et al. (2002) Dendritic cells transport conidia and hyphae of Aspergillus fumigatus from the airways to the draining lymph nodes and initiate disparate Th responses to the fungus. J Immunol 168: 1362-1371. (Pubitemid 34094507)
22. Steele C, Marrero L, Swain S, Harmsen AG, Zheng M, et al. (2003) Alveolar macrophage-mediated killing of Pneumocystis carinii f. sp. muris involves molecular recognition by the Dectin-1 beta-glucan receptor. J Exp Med 198: 1677-1688. (Pubitemid 37494160)
23. Brown GD, Herre J, Williams DL, Willment JA, Marshall AS, et al. (2003) Dectin-1 mediates the biological effects of beta-glucans. J Exp Med 197: 1119-1124. (Pubitemid 36570067)
24. Brown GD, Gordon S (2001) Immune recognition. A new receptor for beta-glucans. Nature 413: 36-37.
25. Ariizumi K, Shen GL, Shikano S, Xu S, Ritter R, et al. (2000) Identification of a novel, dendritic cell-associated molecule, dectin-1, by subtractive cDNA cloning. J Biol Chem 275: 20157-20167. (Pubitemid 30441627)
26. Brown GD, Taylor PR, Reid DM, Willment JA, Williams DL, et al. (2002) Dectin-1 is a major beta-glucan receptor on macrophages. J Exp Med 196: 407-412.
27. Ralph P, Nakoinz I (1997) Antibody-dependent killing of erythrocyte and tumor targets by macrophage-related cell lines: Enhancement by PPD and LPS. J Immunol 119: 950-954.
28. Taylor PR, Brown GD, Reid DM, Willment JA, Martinez-Pomares L, et al. (2002) The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages. J Immunol 169: 3876-3882.
29. Hernandez Y, Herring AC, Huffnagle GB (2004) Pulmonary defenses against fungi. Semin Respir Crit Care Med 25: 63-71.
30. Strieter RM, Belperio JA, Keane MP (2003) Host innate defenses in the lung: Role of cytokines. Curr Opin Infect Dis 16: 193-198. (Pubitemid 36677311)
31. Philippe B, Ibrahim-Granet O, Prevost MC, Gougerot Pocidalo MA, Perez MS, et al. (2003) Killing of Aspergillus fumigatus by alveolar macrophages is mediated by reactive oxygen intermediates. Infect Immun 71: 3034-3042. (Pubitemid 36637524)
32. Ibrahim-Granet O, Philippe B, Boleti H, Boisvieux-Ulrich E, Grenet D, et al. (2003) Phagocytosis and intracellular fate of Aspergillus fumigatus conidia in alveolar macrophages. Infect Immun 71: 891-903. (Pubitemid 36150785)
33. Herre J, Marshall AS, Caron E, Edwards AD, Williams DL, et al. (2004) Dectin-1 utilizes novel mechanisms for yeast phagocytosis in macrophages. Blood 104: 4038-4045. (Pubitemid 39620154)
34. Gantner BN, Simmons RM, Canavera SJ, Akira S, Underhill DM (2003) Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J Exp Med 197: 1107-1117. (Pubitemid 36570066)
35. Tronchin G, Bouchara JP, Ferron M, Larcher G, Chabasse D (1995) Cell surface properties of Aspergillus fumigatus conidia: Correlation between adherence, agglutination, and rearrangements of the cell wall. Can J Microbiol 41: 714-721.
36. Fontaine T, Simenel C, Dubreucq G, Adam O, Delepierre M, et al. (2000) Molecular organization of the alkali-insoluble fraction of Aspergillus fumigatus cell wall. J Biol Chem 275: 27594-27607.
37. Torosantucci A, Bromuro C, Chiani P, De Bernardis F, Berti F, et al. (2005) A novel glycoconjugate vaccine against fungal pathogens. J Exp Med 202: 597-606. (Pubitemid 41258184)
38. Ettinger R, Browning JL, Michie SA, van Ewijk W, McDevitt HO (1996) Disrupted splenic architecture, but normal lymph node development in mice expressing a soluble lymphotoxin-beta receptor-IgG1 fusion protein. Proc Natl Acad Sci U S A 93: 13102-13107.
39. Gao JL, Wynn TA, Chang Y, Lee EJ, Broxmeyer HE, et al. (1997) Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1. J Exp Med 185: 1959-1968.
40. Mehrad B, Strieter RM, Moore TA, Tsai WC, Lira SA, et al. (1999) CXC chemokine receptor-2 ligands are necessary components of neutrophil-mediated host defense in invasive pulmonary aspergillosis. J Immunol 163: 6086-6094.
41. Takeuchi O, Hoshino K, Kawai T, Sanjo H, Takada H, et al. (1999) Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11: 443-451.
42. Rohde M, Schwienbacher M, Nikolaus T, Heesemann J, Ebel F (2002) Detection of early phase specific surface appendages during germination of Aspergillus fumigatus conidia. FEMS Microbiol Lett 206: 99-105.
43. Kolls J, Peppel K, Silva M, Beutler B (1994) Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer. Proc Natl Acad Sci U S A 91: 215-219.