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Volumn 277, Issue 20, 2010, Pages 4241-4253

The Promyelocytic Leukemia Zinc Finger (PLZF) gene is a novel transcriptional target of the CCAAT-Displacement-Protein (CUX1) repressor

Author keywords

colorectal cancer; CUX1; intestinal epithelium; PLZF; transcriptional repression

Indexed keywords

CCAAT BINDING FACTOR; PROMYELOCYTIC LEUKEMIA PROTEIN; RAS PROTEIN; RNA; SUCRASE ISOMALTASE; WNT PROTEIN; ZINC FINGER PROTEIN; 5' UNTRANSLATED REGION; CUX1 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; KRUPPEL LIKE FACTOR; NUCLEAR PROTEIN; REPRESSOR PROTEIN; ZBTB16 PROTEIN, HUMAN;

EID: 77957272261     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2010.07813.x     Document Type: Article
Times cited : (8)

References (53)
  • 1
    • 0034605043 scopus 로고    scopus 로고
    • Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity
    • Kunkel EJ, Campbell JJ, Haraldsen G, Pan J, Boisvert J, Roberts AI, Ebert EC, Vierra MA, Goodman SB, Genovese MC et al. (2000) Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity. J Exp Med 192, 761 768.
    • (2000) J Exp Med , vol.192 , pp. 761-768
    • Kunkel, E.J.1    Campbell, J.J.2    Haraldsen, G.3    Pan, J.4    Boisvert, J.5    Roberts, A.I.6    Ebert, E.C.7    Vierra, M.A.8    Goodman, S.B.9    Genovese, M.C.10
  • 2
    • 0030702089 scopus 로고    scopus 로고
    • Epithelial cell growth and differentiation V. Transcriptional regulation, development, and neoplasia of the intestinal epithelium
    • 36-5
    • Traber PG (1997) Epithelial cell growth and differentiation. V. Transcriptional regulation, development, and neoplasia of the intestinal epithelium. Am J Physiol 273, G979 G981. (Pubitemid 27508257)
    • (1997) American Journal of Physiology - Gastrointestinal and Liver Physiology , vol.273 , Issue.5
    • Traber, P.G.1
  • 3
    • 0020513908 scopus 로고
    • Sucrase-isomaltase: A marker of foetal and malignant epithelial cells of the human colon
    • Zweibaum A, Triadou N, Kedinger M, Augeron C, Robine-Leon S, Pinto M, Rousset M Haffen K (1983) Sucrase-isomaltase: a marker of foetal and malignant epithelial cells of the human colon. Int J Cancer 32, 407 412. (Pubitemid 13017953)
    • (1983) International Journal of Cancer , vol.32 , Issue.4 , pp. 407-412
    • Zweibaum, A.1    Triadou, N.2    Kedinger, M.3
  • 4
    • 0025215624 scopus 로고
    • Detection and characterization of sucrase-isomaltase in adult human colon and in colonic polyps
    • Beaulieu JF, Weiser MM, Herrera L Quaroni A (1990) Detection and characterization of sucrase-isomaltase in adult human colon and in colonic polyps. Gastroenterology 98, 1467 1477. (Pubitemid 20158608)
    • (1990) Gastroenterology , vol.98 , Issue.6 , pp. 1467-1477
    • Beaulieu, J.-F.1    Weiser, M.M.2    Herrera, L.3    Quaroni, A.4
  • 5
    • 0032411880 scopus 로고    scopus 로고
    • Expression of sucrase and intestinal-type alkaline phosphatase in colorectal carcinomas in rats treated with methylazoxymethanol acetate
    • DOI 10.1007/s004320050231
    • Yoshida K, Nakamura W, Hirano K, Yuasa H, Tsukamoto T Tatematsu M (1998) Expression of sucrase and intestinal-type alkaline phosphatase in colorectal carcinomas in rats treated with methylazoxymethanol acetate. J Cancer Res Clin Oncol 124, 677 682. (Pubitemid 29003300)
    • (1998) Journal of Cancer Research and Clinical Oncology , vol.124 , Issue.12 , pp. 677-682
    • Yoshida, K.1    Nakamura, W.2    Hirano, K.3    Yuasa, H.4    Tsukamoto, T.5    Tatematsu, M.6
  • 6
    • 0026609311 scopus 로고
    • Intestinal brush-border-associated enzymes: Co-ordinated expression in colorectal cancer
    • Real FX, Xu M, Vila MR de Bolos C (1992) Intestinal brush-border- associated enzymes: co-ordinated expression in colorectal cancer. Int J Cancer 51, 173 181.
    • (1992) Int J Cancer , vol.51 , pp. 173-181
    • Real, F.X.1    Xu, M.2    Vila, M.R.3    De Bolos, C.4
  • 7
    • 0028302971 scopus 로고
    • Morphological changes and cellular proliferation in mouse colon during fetal and postnatal development
    • Menard D, Dagenais P Calvert R (1994) Morphological changes and cellular proliferation in mouse colon during fetal and postnatal development. Anat Rec 238, 349 359. (Pubitemid 24079438)
    • (1994) Anatomical Record , vol.238 , Issue.3 , pp. 349-359
    • Menard, D.1    Dagenais, P.2    Calvert, R.3
  • 10
    • 0035972762 scopus 로고    scopus 로고
    • Role of the multifunctional CDP/Cut/Cux homeodomain transcription factor in regulating differentiation, cell growth and development
    • DOI 10.1016/S0378-1119(01)00485-1, PII S0378111901004851
    • Nepveu A (2001) Role of the multifunctional CDPCutCux homeodomain transcription factor in regulating differentiation, cell growth and development. Gene 270, 1 15. (Pubitemid 32525797)
    • (2001) Gene , vol.270 , Issue.1-2 , pp. 1-15
    • Nepveu, A.1
  • 11
    • 0029834445 scopus 로고    scopus 로고
    • The human Cut homeodomain protein can repress gene expression by two distinct mechanisms: Active repression and competition for binding site occupancy
    • Mailly F, Berube G, Harada R, Mao PL, Phillips S Nepveu A (1996) The human cut homeodomain protein can repress gene expression by two distinct mechanisms: active repression and competition for binding site occupancy. Mol Cell Biol 16, 5346 5357. (Pubitemid 26315053)
    • (1996) Molecular and Cellular Biology , vol.16 , Issue.10 , pp. 5346-5357
    • Mailly, F.1    Berube, G.2    Harada, R.3    Mao, P.-L.4    Phillips, S.5    Nepveu, A.6
  • 12
    • 40649109025 scopus 로고    scopus 로고
    • The multiple roles of CUX1: Insights from mouse models and cell-based assays
    • Sansregret L Nepveu A (2008) The multiple roles of CUX1: insights from mouse models and cell-based assays. Gene 412, 84 94.
    • (2008) Gene , vol.412 , pp. 84-94
    • Sansregret, L.1    Nepveu, A.2
  • 13
    • 0028176779 scopus 로고
    • The human Cut homeodomain protein represses transcription from the c-myc promoter
    • Dufort D Nepveu A (1994) The human cut homeodomain protein represses transcription from the c-myc promoter. Mol Cell Biol 14, 4251 4257. (Pubitemid 2091036)
    • (1994) Molecular and Cellular Biology , vol.14 , Issue.6 , pp. 4251-4257
    • Dufort, D.1    Nepveu, A.2
  • 14
    • 0032541492 scopus 로고    scopus 로고
    • The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which downmodulates p21(WAF1/CIP1/SDI1) in S phase
    • DOI 10.1093/emboj/17.16.4680
    • Coqueret O, Berube G Nepveu A (1998) The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which downmodulates p21WAF1CIP1SDI1 in S phase. EMBO J 17, 4680 4694. (Pubitemid 28377168)
    • (1998) EMBO Journal , vol.17 , Issue.16 , pp. 4680-4694
    • Coqueret, O.1    Berube, G.2    Nepveu, A.3
  • 17
  • 18
    • 0027411688 scopus 로고
    • Fusion between a novel Kruppel-like zinc finger gene and the retinoic acid receptor-α locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia
    • Chen Z, Brand NJ, Chen A, Chen SJ, Tong JH, Wang ZY, Waxman S Zelent A (1993) Fusion between a novel Kruppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia. EMBO J 12, 1161 1167. (Pubitemid 23095865)
    • (1993) EMBO Journal , vol.12 , Issue.3 , pp. 1161-1167
    • Chen, Z.1    Brand, N.J.2    Chen, A.3    Chen, S.-J.4    Tong, J.-H.5    Wang, Z.-Y.6    Waxman, S.7    Zelent, A.8
  • 19
    • 0028818983 scopus 로고
    • Leukemia translocation gene, PLZF, is expressed with a speckled nuclear pattern in early hematopoietic progenitors
    • Reid A, Gould A, Brand N, Cook M, Strutt P, Li J, Licht J, Waxman S, Krumlauf R Zelent A (1995) Leukemia translocation gene, PLZF, is expressed with a speckled nuclear pattern in early hematopoietic progenitors. Blood 86, 4544 4552.
    • (1995) Blood , vol.86 , pp. 4544-4552
    • Reid, A.1    Gould, A.2    Brand, N.3    Cook, M.4    Strutt, P.5    Li, J.6    Licht, J.7    Waxman, S.8    Krumlauf, R.9    Zelent, A.10
  • 20
    • 0033838360 scopus 로고    scopus 로고
    • In-depth mutational analysis of the promyelocytic leukemia zinc finger BTB/POZ domain reveals motifs and residues required for biological and transcriptional functions
    • DOI 10.1128/MCB.20.17.6550-6567.2000
    • Melnick A, Ahmad KF, Arai S, Polinger A, Ball H, Borden KL, Carlile GW, Prive GG Licht JD (2000) In-depth mutational analysis of the promyelocytic leukemia zinc finger BTBPOZ domain reveals motifs and residues required for biological and transcriptional functions. Mol Cell Biol 20, 6550 6567. (Pubitemid 30650240)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.17 , pp. 6550-6567
    • Melnick, A.1    Ahmad, F.K.2    Arai, S.3    Polinger, A.4    Ball, H.5    Borden, K.L.6    Carlile, G.W.7    Prive, G.G.8    Licht, J.D.9
  • 21
    • 33750333540 scopus 로고    scopus 로고
    • POZ for effect - POZ-ZF transcription factors in cancer and development
    • DOI 10.1016/j.tcb.2006.09.003, PII S096289240600239X
    • Kelly KF Daniel JM (2006) POZ for effect - POZ-ZF transcription factors in cancer and development. Trends Cell Biol 16, 578 587. (Pubitemid 44636217)
    • (2006) Trends in Cell Biology , vol.16 , Issue.11 , pp. 578-587
    • Kelly, K.F.1    Daniel, J.M.2
  • 24
    • 0034123470 scopus 로고    scopus 로고
    • Plzf regulates limb and axial skeletal patterning
    • DOI 10.1038/76014
    • Barna M, Hawe N, Niswander L Pandolfi PP (2000) Plzf regulates limb and axial skeletal patterning. Nat Genet 25, 166 172. (Pubitemid 30394986)
    • (2000) Nature Genetics , vol.25 , Issue.2 , pp. 166-172
    • Barna, M.1    Hawe, N.2    Lee, N.3    Pandolfi, P.P.4
  • 25
    • 0037099457 scopus 로고    scopus 로고
    • C. elegans EOR-1PLZF and EOR-2 positively regulate Ras and Wnt signaling and function redundantly with LIN-25 and the SUR-2 Mediator component
    • Howard RM Sundaram MV (2002) C. elegans EOR-1PLZF and EOR-2 positively regulate Ras and Wnt signaling and function redundantly with LIN-25 and the SUR-2 Mediator component. Genes Dev 16, 1815 1827.
    • (2002) Genes Dev , vol.16 , pp. 1815-1827
    • Howard, R.M.1    Sundaram, M.V.2
  • 26
    • 0034103928 scopus 로고    scopus 로고
    • Molecular interactions in the Vogelstein model of colorectal carcinoma
    • Arends JW (2000) Molecular interactions in the Vogelstein model of colorectal carcinoma. J Pathol 190, 412 416.
    • (2000) J Pathol , vol.190 , pp. 412-416
    • Arends, J.W.1
  • 27
    • 0037409182 scopus 로고    scopus 로고
    • The molecular pathogenesis of acute promyelocytic leukaemia: Implications for the clinical management of the disease
    • DOI 10.1016/S0268-960X(02)00075-9
    • Mistry AR, Pedersen EW, Solomon E Grimwade D (2003) The molecular pathogenesis of acute promyelocytic leukaemia: implications for the clinical management of the disease. Blood Rev 17, 71 97. (Pubitemid 36372973)
    • (2003) Blood Reviews , vol.17 , Issue.2 , pp. 71-97
    • Mistry, A.R.1    Pedersen, E.W.2    Solomon, E.3    Grimwade, D.4
  • 28
    • 0025024105 scopus 로고
    • Sucrase-isomaltase: A marker associated with the progression of adenomatous polyps to adenocarcinomas
    • Wiltz O, O'Hara CJ, Steele GD Mercurio AM (1990) Sucrase-isomaltase: a marker associated with the progression of adenomatous polyps to adenocarcinomas. Surgery 108, 269 275. (Pubitemid 20255461)
    • (1990) Surgery , vol.108 , Issue.2 , pp. 269-276
    • Wiltz, O.1    O'Hara, C.J.2    Steele, G.D.3    Mercurio, A.M.4
  • 32
    • 21244485110 scopus 로고    scopus 로고
    • Sp1 elements in SULT2B1b promoter and 5′-untranslated region of mRNA: Sp1/Sp2 induction and augmentation by histone deacetylase inhibition
    • DOI 10.1016/j.febslet.2005.05.041, PII S0014579305006599
    • Lee YC, Higashi Y, Luu C, Shimizu C Strott CA (2005) Sp1 elements in SULT2B1b promoter and 5′-untranslated region of mRNA: Sp1Sp2 induction and augmentation by histone deacetylase inhibition. FEBS Lett 579, 3639 3645. (Pubitemid 40897704)
    • (2005) FEBS Letters , vol.579 , Issue.17 , pp. 3639-3645
    • Lee, Y.C.1    Higashi, Y.2    Luu, C.3    Shimizu, C.4    Strott, C.A.5
  • 33
    • 20744442273 scopus 로고    scopus 로고
    • Characterization of a novel positive transcription regulatory element that differentially regulates the insulin-like growth factor binding protein-3 (IGFBP-3) gene in senescent cells
    • Lu XF, Jiang XG, Lu YB, Bai JH Mao ZB (2005) Characterization of a novel positive transcription regulatory element that differentially regulates the insulin-like growth factor binding protein-3 (IGFBP-3) gene in senescent cells. J Biol Chem 280, 22606 22615.
    • (2005) J Biol Chem , vol.280 , pp. 22606-22615
    • Lu, X.F.1    Jiang, X.G.2    Lu, Y.B.3    Bai, J.H.4    Mao, Z.B.5
  • 34
    • 42949167436 scopus 로고    scopus 로고
    • The RHOX5 homeodomain protein mediates transcriptional repression of the netrin-1 receptor gene Unc5c
    • Hu Z, Shanker S, MacLean JA II., Ackerman SL Wilkinson MF (2008) The RHOX5 homeodomain protein mediates transcriptional repression of the netrin-1 receptor gene Unc5c. J Biol Chem 283, 3866 3876.
    • (2008) J Biol Chem , vol.283 , pp. 3866-3876
    • Hu, Z.1    Shanker, S.2    MacLean II, J.A.3    Ackerman, S.L.4    Wilkinson, M.F.5
  • 35
    • 0035724764 scopus 로고    scopus 로고
    • S phase-specific proteolytic cleavage is required to activate stable DNA binding by the CDP/Cut homeodomain protein
    • DOI 10.1128/MCB.21.18.6332-6345.2001
    • Moon NS, Premdas P, Truscott M, Leduy L, Berube G Nepveu A (2001) S phase-specific proteolytic cleavage is required to activate stable DNA binding by the CDPCut homeodomain protein. Mol Cell Biol 21, 6332 6345. (Pubitemid 34263531)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.18 , pp. 6332-6345
    • Sung Moon, N.1    Premdas, P.2    Truscott, M.3    Leduy, L.4    Berube, G.5    Nepveu, A.6
  • 36
    • 0027489411 scopus 로고
    • The mouse homeodomain protein Phox2 regulates Ncam promoter activity in concert with Cux/CDP and is a putative determinant of neurotransmitter phenotype
    • Valarche I, Tissier-Seta JP, Hirsch MR, Martinez S, Goridis C Brunet JF (1993) The mouse homeodomain protein Phox2 regulates Ncam promoter activity in concert with CuxCDP and is a putative determinant of neurotransmitter phenotype. Development (Cambridge, England) 119, 881 896. (Pubitemid 23337428)
    • (1993) Development , vol.119 , Issue.3 , pp. 881-896
    • Valarche, I.1    Tissier-Seta, J.-P.2    Hirsch, M.-R.3    Martinez, S.4    Goridis, C.5    Brunet, J.-F.6
  • 39
    • 0036681257 scopus 로고    scopus 로고
    • Expression of N-terminally truncated isoforms of CDPCUX is increased in human uterine leiomyomas
    • Moon NS, Rong Zeng W, Premdas P, Santaguida M, Berube G Nepveu A (2002) Expression of N-terminally truncated isoforms of CDPCUX is increased in human uterine leiomyomas. Int J Cancer 100, 429 432.
    • (2002) Int J Cancer , vol.100 , pp. 429-432
    • Moon, N.S.1    Rong Zeng, W.2    Premdas, P.3    Santaguida, M.4    Berube, G.5    Nepveu, A.6
  • 40
    • 0029874494 scopus 로고    scopus 로고
    • Molecular definition of a narrow interval at 7q22.1 associated with myelodysplasia
    • Johnson EJ, Scherer SW, Osborne L, Tsui LC, Oscier D, Mould S Cotter FE (1996) Molecular definition of a narrow interval at 7q22.1 associated with myelodysplasia. Blood 87, 3579 3586. (Pubitemid 26129584)
    • (1996) Blood , vol.87 , Issue.9 , pp. 3579-3586
    • Johnson, E.J.1    Scherer, S.W.2    Osborne, L.3    Tsui, L.C.4    Oscier, D.5    Mould, S.6    Cotter, F.E.7
  • 42
    • 1842295700 scopus 로고    scopus 로고
    • Molecular cytogenetic delineation of deletions and translocations involving chromosome band 7q22 in myeloid leukemias
    • Fischer K, Frohling S, Scherer SW, McAllister Brown J, Scholl C, Stilgenbauer S, Tsui LC, Lichter P Dohner H (1997) Molecular cytogenetic delineation of deletions and translocations involving chromosome band 7q22 in myeloid leukemias. Blood 89, 2036 2041. (Pubitemid 27132119)
    • (1997) Blood , vol.89 , Issue.6 , pp. 2036-2041
    • Fischer, K.1    Frohling, S.2    Scherer, S.W.3    Brown, J.M.4    Scholl, C.5    Stilgenbauer, S.6    Tsui, L.-C.7    Lichter, P.8    Dohner, H.9
  • 44
    • 0032795454 scopus 로고    scopus 로고
    • Delineation of multiple deleted regions in 7q in myeloid disorders
    • DOI 10.1002/(SICI)1098-2264(199908)25:4<384::AID-GCC11>3.0.CO;2-D
    • Tosi S, Scherer SW, Giudici G, Czepulkowski B, Biondi A Kearney L (1999) Delineation of multiple deleted regions in 7q in myeloid disorders. Genes Chromosomes Cancer 25, 384 392. (Pubitemid 29326146)
    • (1999) Genes Chromosomes and Cancer , vol.25 , Issue.4 , pp. 384-392
    • Tosi, S.1    Scherer, S.W.2    Giudici, G.3    Czepulkowski, B.4    Biondi, A.5    Kearney, L.6
  • 46
    • 33845352215 scopus 로고    scopus 로고
    • Wnt signaling and gastrointestinal tumorigenesis in mouse models
    • DOI 10.1038/sj.onc.1210058, PII 1210058
    • Taketo MM (2006) Wnt signaling and gastrointestinal tumorigenesis in mouse models. Oncogene 25, 7522 7530. (Pubitemid 44885751)
    • (2006) Oncogene , vol.25 , Issue.57 , pp. 7522-7530
    • Taketo, M.M.1
  • 47
    • 0036328995 scopus 로고    scopus 로고
    • Targeted expression of oncogenic K-ras in intestinal epithelium causes spontaneous tumorigenesis in mice
    • DOI 10.1053/gast.2002.34786
    • Janssen KP, el-Marjou F, Pinto D, Sastre X, Rouillard D, Fouquet C, Soussi T, Louvard D Robine S (2002) Targeted expression of oncogenic K-ras in intestinal epithelium causes spontaneous tumorigenesis in mice. Gastroenterology 123, 492 504. (Pubitemid 34827194)
    • (2002) Gastroenterology , vol.123 , Issue.2 , pp. 492-504
    • Janssen, K.1    Marjou, F.E.2    Pinto, D.3    Sastre, X.4    Rouillard, D.5    Fouquet, C.6    Soussi, T.7    Louvard, D.8    Robine, S.9
  • 48
    • 0037200071 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor-1α, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription: Implication for the developmental regulation of the sucrase-isomaltase gene
    • DOI 10.1074/jbc.M204622200
    • Boudreau F, Rings EH, van Wering HM, Kim RK, Swain GP, Krasinski SD, Moffett J, Grand RJ, Suh ER Traber PG (2002) Hepatocyte nuclear factor-1 alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene. J Biol Chem 277, 31909 31917. (Pubitemid 34968999)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.35 , pp. 31909-31917
    • Boudreau, F.1    Rings, E.H.H.M.2    Van Wering, H.M.3    Kim, R.K.4    Swain, G.P.5    Krasinski, S.D.6    Moffett, J.7    Grand, R.J.8    Suh, E.R.9    Traber, P.G.10
  • 49
    • 0026317501 scopus 로고
    • Clonal analysis of sucrase-isomaltase expression in the human colon adenocarcinoma Caco-2 cells
    • Beaulieu JF Quaroni A (1991) Clonal analysis of sucrase-isomaltase expression in the human colon adenocarcinoma Caco-2 cells. Biochem J 280 (Pt 3, 599 608.
    • (1991) Biochem J 280 (Pt , vol.3 , pp. 599-608
    • Beaulieu, J.F.1    Quaroni, A.2
  • 51
    • 3342929529 scopus 로고    scopus 로고
    • Transcript profiling during preimplantation mouse development
    • DOI 10.1016/j.ydbio.2004.05.018, PII S0012160604003628
    • Zeng F, Baldwin DA Schultz RM (2004) Transcript profiling during preimplantation mouse development. Dev Biol 272, 483 496. (Pubitemid 38988270)
    • (2004) Developmental Biology , vol.272 , Issue.2 , pp. 483-496
    • Zeng, F.1    Baldwin, D.A.2    Schultz, R.M.3
  • 52
    • 0035223264 scopus 로고    scopus 로고
    • Electrophoretic mobility shift assays for the analysis of DNA-protein interactions
    • Laniel MA, Beliveau A Guerin SL (2001) Electrophoretic mobility shift assays for the analysis of DNA-protein interactions. Methods Mol Biol (Clifton, NJ) 148, 13 30.
    • (2001) Methods Mol Biol (Clifton, NJ) , vol.148 , pp. 13-30
    • Laniel, M.A.1    Beliveau, A.2    Guerin, S.L.3
  • 53
    • 0030010377 scopus 로고    scopus 로고
    • Use of the dissociating enzyme thermolysin to generate viable human normal intestinal epithelial cell cultures
    • DOI 10.1006/excr.1996.0145
    • Perreault N Jean-Francois B (1996) Use of the dissociating enzyme thermolysin to generate viable human normal intestinal epithelial cell cultures. Exp Cell Res 224, 354 364. (Pubitemid 26140569)
    • (1996) Experimental Cell Research , vol.224 , Issue.2 , pp. 354-364
    • Perreault, N.1    Beaulieu, J.-F.2


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