Disruption of Nrf2 enhances susceptibility to airway inflammatory responses induced by low-dose diesel exhaust particles in mice

Clinical Immunology

Volumn 128, Issue 3, 2008, Pages 366-373

  Li, Ying Ji ^a,c   Takizawa, Hajime ^b   Azuma, Arata ^a   Kohyama, Tadashi ^d   Yamauchi, Yasuhiro ^d   Takahashi, Satoru ^e   Yamamoto, Masayuki ^e   Kawada, Tomoyuki ^a   Kudoh, Shoji ^a   Sugawara, Isamu ^c  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b TEIKYO UNIVERSITY   (Japan)

^c RESEARCH INSTITUTE OF TUBERCULOSIS   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Airway hyperresponsiveness; Cytokine; Diesel exhaust particle; Eosinophils; Mouse model; Nrf2

Indexed keywords

INTERLEUKIN 12; INTERLEUKIN 13; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRONCHUS HYPERREACTIVITY; C57BL 6 MOUSE; CONTROLLED STUDY; EOSINOPHIL COUNT; EXHAUST GAS; GENE DISRUPTION; GENE EXPRESSION; INFLAMMATION; KNOCKOUT MOUSE; LYMPHOCYTE COUNT; MOUSE; NONHUMAN; OXIDATIVE STRESS; PNEUMONIA; PRIORITY JOURNAL;

ANIMALS; ANTIOXIDANTS; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; CYTOKINES; DISEASE SUSCEPTIBILITY; ENZYME INDUCTION; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INFLAMMATION; INHALATION EXPOSURE; LUNG; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; RESPIRATORY SYSTEM; VEHICLE EMISSIONS;

EID: 49149126354     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2008.05.005     Document Type: Article

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