15d-PGJ2 stimulates HO-1 expression through p38 MAP kinase and Nrf-2 pathway in rat vascular smooth muscle cells

Toxicology and Applied Pharmacology

Volumn 223, Issue 1, 2007, Pages 20-27

  Lim, Hyun Joung ^a   Lee, Kuy Sook ^a   Lee, Seahyoung ^a,b   Park, Jin Hee ^a   Choi, Hye Eun ^a   Go, Sang Hee ^a   Kwak, Hyun Jeong ^a   Park, Hyun Young ^a  

^a Korea National Institute of Health   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

15d PGJ2; HO 1; Nrf 2; Smooth muscle cell

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 CHLORO 5 NITROBENZANILIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BETA ACTIN; DELTA15 PROSTAGLANDIN J2; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA ANTAGONIST; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROSTAGLANDIN J2; REACTIVE OXYGEN METABOLITE; RNA; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; WORTMANNIN; 15 DEOXYPROSTAGLANDIN J2; 15-DEOXYPROSTAGLANDIN J2; DRUG DERIVATIVE; ENZYME INHIBITOR; MESSENGER RNA; PROSTAGLANDIN D2; SCAVENGER;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; FLOW CYTOMETRY; IMMUNOCYTOCHEMISTRY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THORACIC AORTA; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CELL PROLIFERATION; CYTOLOGY; DRUG ANTAGONISM; DRUG COMBINATION; DRUG EFFECT; GENE EXPRESSION; GENETICS; METABOLISM; SMOOTH MUSCLE FIBER; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; AORTA, THORACIC; CELL PROLIFERATION; CELLS, CULTURED; DRUG ANTAGONISM; DRUG COMBINATIONS; ENZYME INHIBITORS; FREE RADICAL SCAVENGERS; GENE EXPRESSION; HEME OXYGENASE-1; MYOCYTES, SMOOTH MUSCLE; NF-E2-RELATED FACTOR 2; NITRIC OXIDE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROSTAGLANDIN D2; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RNA, MESSENGER;

EID: 34547676833     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.04.019     Document Type: Article

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