Loss of β1-integrin enhances TGF-β1-induced collagen expression in epithelial cells via increased αvβ3-integrin and Rac1 activity

Journal of Biological Chemistry

Volumn 285, Issue 40, 2010, Pages 30741-30751

  Hayashida, Tomoko ^a,b   Jones, Jonathan C R ^a   Lee, Carrie K ^a   Schnaper, H William ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Children's Memorial Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PARTNERS; COLLAGEN EXPRESSION; EPITHELIAL CELLS; FIBROGENESIS; FOCAL ADHESION KINASE; FOCAL ADHESIONS; HUMAN KIDNEY; IN-CELL; INTEGRINS; KIDNEY CELLS; MAP KINASE; MRNA EXPRESSION; PEPTIDE INHIBITORS; PROMOTER ACTIVITIES; RENAL CELL; SMAD3 LINKER REGION; SURFACE EXPRESSION; TRANSFORMING GROWTH FACTORS; TUBULAR CELLS; TYPE I COLLAGEN;

ADHESION; CELL CULTURE; COLLAGEN; PEPTIDES; PHOSPHORYLATION;

CELLS;

ALPHA5 INTEGRIN; BETA1 INTEGRIN; BETA3 INTEGRIN; COL1A2 PROTEIN; COLLAGEN TYPE 1; COLLAGEN TYPE 1 ALPHA2; RAC1 PROTEIN; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR; ALPHA 2(I) COLLAGEN; BETA INTEGRIN; COLLAGEN; FOCAL ADHESION KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE; PTK2 PROTEIN, HUMAN; RAC1 PROTEIN, HUMAN;

ARTICLE; CELL SURFACE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EPITHELIUM CELL; FIBROGENESIS; FOCAL ADHESION; GENE EXPRESSION; HUMAN; HUMAN CELL; KIDNEY TUBULE CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION; BIOSYNTHESIS; CELL LINE; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; KIDNEY TUBULE; METABOLISM;

CELL LINE; COLLAGEN; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FOCAL ADHESION KINASE 1; FOCAL ADHESIONS; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; INTEGRIN ALPHAVBETA3; INTEGRIN BETA CHAINS; KIDNEY TUBULES; RAC1 GTP-BINDING PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 77957252478     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.105700     Document Type: Article

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