Podophyllotoxin: Current approaches to its biotechnological production and future challenges

Engineering in Life Sciences

Volumn 10, Issue 4, 2010, Pages 281-292

  Yousefzadi, Morteza ^a   Sharifi, Mozafar ^a   Behmanesh, Mehrdad ^a   Moyano, Elisabeth ^b   Bonfill, Mercedis ^c   Cusido, Rosa M ^c   Palazon, Javier ^c  

^a TARBIAT MODARES UNIVERSITY   (Iran)

^b UNIVERSITAT POMPEU FABRA   (Spain)

^c UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Lignans; Linum sp.; Metabolic engineering; Podophyllotoxin derivatives; Podophyllum sp.

Indexed keywords

LIGNANS; LINUM SP.; METABOLIC ENGINEERING; PODOPHYLLOTOXIN DERIVATIVES; PODOPHYLLUM;

BIOSYNTHESIS; BIOTECHNOLOGY; METABOLISM;

CELL CULTURE;

ANTIDOTE; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; ETOPOFOS; ETOPOSIDE; PACLITAXEL; PLANT EXTRACT; PODOPHYLLOTOXIN; PODOPHYLLOTOXIN DERIVATIVE; PODOPHYLLUM EXTRACT; TENIPOSIDE; TETRALIN DERIVATIVE; UNCLASSIFIED DRUG; VINBLASTINE; VINCRISTINE;

ALKALOID; BIOENGINEERING; BIOTRANSFORMATION; CANCER; FUTURE PROSPECT; METABOLISM; PERENNIAL PLANT; TOXIN;

ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; BIOSYNTHESIS; BIOTRANSFORMATION; CANCER THERAPY; CELL CULTURE; CONDYLOMA ACUMINATUM; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; INTOXICATION; LEUKEMIA; LUNG CANCER; METABOLIC ENGINEERING; NEOPLASM; NONHUMAN; PLANT BIOTECHNOLOGY; PLANT ROOT; PODOPHYLLUM; REVIEW; SKIN DISEASE; SOLID TUMOR; STRUCTURE ACTIVITY RELATION;

CATHARANTHUS ROSEUS; LINUM; PODOPHYLLUM;

EID: 77956912605     PISSN: 16180240     EISSN: 16182863     Source Type: Journal    
DOI: 10.1002/elsc.201000027     Document Type: Review

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