Accumulation of podophyllotoxin and related lignans in cell suspension cultures of Linum album

Phytochemistry

Volumn 48, Issue 6, 1998, Pages 975-979

  Smollny, Thomas ^a   Wickers, Harry ^b   Kalenberg, Sabine ^a   Shahsavari, Abbas ^c   Petersen, Maike ^d   Alfermann, A Wilhelm ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b WAGENINGEN UNIVERSITY   (Netherlands)

^c RESEARCH INSTITUTE OF FORESTS AND RANGELANDS   (Iran)

^d PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

5 Methoxypodophyllotoxin; Biosynthesis; Coniferin; Lignans; Linaceae; Linum album; Plant cell cultures; Podophyllotoxin; White flax

Indexed keywords

ALPHA PELTATIN; LIGNAN; MATAIRESINOL; MEDICINAL PLANT; PINORESINOL; PODOPHYLLOTOXIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CULTURE; CHEMICAL ANALYSIS; DRUG SYNTHESIS; NONHUMAN; PLANT CELL; STRUCTURE ANALYSIS;

LINUM ALBUM;

EID: 0031776501     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9422(97)00957-6     Document Type: Article

References (25)

1. Stähelin, H. and von Wartburg, A., Progr. Drug. Res., 1989, 33, 169.
2. Jackson, D. E. and Dewick, P. M., Phytochemistry, 1984, 23, 1147.
3. Rust, R. W. and Roth, R. R., Nature, 1981, 105, 51.
4. Ayres, D. C. and Loike, J. D., Lignans. Chemical Biological and Clinical Properties. Cambridge University Press, Cambridge, 1990.
5. Arumugam, N. and Bhojwani, S. S., Can. J. Bot., 1990, 68, 487.
6. Fujii, Y., in Biotechnology in Forestry and Agriculture, Vol. 15, ed. Y. P. S. Bajaj. Springer, Berlin, 1991, p. 362.
7. Kadkade, P. G., Naturwissenschaften, 1981, 68, 481.
8. van Uden, W., Pras, N., Visser, F. and Malingré, T. M., Plant Cell Rep., 1989, 8, 165.
9. van Uden, W., Pras, N. and Malingré, T. M., Plant Cell Rep., 1990, 9, 257.
10. van Uden, W., Pras, N., Malingré, T. M., Plant Cell, Tissue Org. Cult., 1990, 23, 217.
11. Berlin, J., Wray, V., Mollenschott, C. and Sasse, F., J. Nat. Prod., 1986, 49, 435.
12. van Uden, W., Pras, N., Vossebeld, E. M., Mol, J. M. N. and Malingré, T. M., Plant Cell, Tissue Org. Cult., 1990, 20, 81.
13. van Uden, W., Pras, N., Homan, B. and Malingré, T. M., Plant Cell, Tissue Org. Cult., 1991, 27, 115.
14. Wichers, H. J., Harkes, H. P. and Arroo, R. R. J., Plant Cell, Tissue Org. Cult., 1990, 23, 93.
15. Wichers, J. H., Versluis-De Haan, G. G., Marsman, J. W. and Harkes, M. P., Phytochemistry, 1991, 30, 3601.
16. Weiss, S. G., Tin-Wa, M., Perdue, R. E. and Farnsworth, N. R., J. Pharm. Sci., 1975, 64, 95.
17. Smollny, T., Wichers, H., de Rijk, T., van Zwam, A., Shahsavari, A. and Alfermann, A. W., Planta Med., 1992, 58(Suppl. 1), A622.
18. Berlin, J., Bedorf, N., Mollenschott, C., Sasse, F. and Höfle, G., Planta Med., 1988, 54, 204.
19. Dewick, P. M., in Studies in Natural Products Chemistry, Vol. 5, Structure Elucidation (Part B), ed. H. E. J. Atta-ur-Rahman. Elsevier, Amsterdam, 1989, p. 459.
20. Davin, L. B., Bedgar, D. L., Katayama, T. and Lewis, N. G. Phytochemistry 31, 3869.
21. Davin, L. B., Lewis, N. G., in Phenolic Metabolism in Plants, ed. H. A. Stafford and R. K. Ibrahim. Plenum Press, New York, 1990, p. 325.
22. Zenk, M. H., El-Shagi, H., Arens, H., Stöckigt, J., Weiler, E. W. and Deus, B., in Plant Tissue Culture and its Bio-Technological Application, ed. W. Barz, E. Reinhard, M. H. Zenk. Springer, Berlin, 1977, p. 27.
23. Murashige, T. and Skoog, F., Physiol. Plant., 1962, 15, 473.
24. Sadowska, A., Wiweger, U., Lata, B. and Obidoska, G., Biologia Plantarum, 1997, 39, 331.
25. Moraes-Cerdeira, R. M., Burandt, Jr., C. L., Bastos, J. K., Nanayakkara, N. P. D. and McChesney, J. D., Planta Medica, 1998, 64, 42.