A novel biotransformation process of 4′-demethylepipodophyllotoxin to 4′-demethylepipodophyllic acid by Bacillus fusiformis CICC 20463, Part II: Process optimization

Bioprocess and Biosystems Engineering

Volumn 33, Issue 2, 2010, Pages 237-246

  Tang, Ya Jie ^a,b   Xu, Xiao Ling ^a   Zhong, Jian Jiang ^c  

^a HUBEI UNIVERSITY OF TECHNOLOGY   (China)

^b INSTITUTE OF PROCESS ENGINEERING   (China)

^c Shanghai Jiao Tong University   (China)

Author keywords

4 Demethylepipodophyllic acid; 4 Demethylepipodophyllotoxin; Bacillus fusiformis; Biotransformation process optimization

Indexed keywords

BACILLUS FUSIFORMIS; BIOTRANSFORMATION PROCESS; BIOTRANSFORMATION PROCESS OPTIMIZATION; MEDIUM COMPOSITION; PROCESS OPTIMIZATION; SUBSTRATE CONCENTRATIONS; TANK BIOREACTORS; YEAST EXTRACTS;

ACIDS; BACTERIOLOGY; BIOCHEMISTRY; BIOCONVERSION; CELL CULTURE; CELL GROWTH; GROWTH KINETICS; PROCESS CONTROL; SODIUM CHLORIDE; SUBSTRATES; SUGAR (SUCROSE);

OPTIMIZATION;

4' DEMETHYLEPIPODOPHYLLIC ACID; 4' NOREPIPODOPHYLLOTOXIN; EPIPODOPHYLLOTOXIN DERIVATIVE; NITROGEN; UNCLASSIFIED DRUG;

ARTICLE; BIOTRANSFORMATION; CELL GROWTH; FUSOBACTERIUM NUCLEATUM; NONHUMAN; PRIORITY JOURNAL;

BACILLUS; BIOREACTORS; BIOTECHNOLOGY; BIOTRANSFORMATION; HYDROGEN-ION CONCENTRATION; INDUSTRIAL MICROBIOLOGY; KINETICS; MODELS, CHEMICAL; MODELS, STATISTICAL; NITROGEN; PODOPHYLLOTOXIN; SODIUM CHLORIDE; SUCROSE; SURFACE PROPERTIES;

BACILLUS FUSIFORMIS;

EID: 77649234268     PISSN: 16157591     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00449-009-0317-x     Document Type: Article

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