-
1
-
-
0032480248
-
Cancer phenotype correlates with constitutional TP53 genotype in families with the Li-Fraumeni syndrome
-
Birch J.M., Blair V., Kelsey A.M., Evans D.G., Harris M., Tricker K.J., Varley J.M. Cancer phenotype correlates with constitutional TP53 genotype in families with the Li-Fraumeni syndrome. Oncogene 1998, 17:1061-1068.
-
(1998)
Oncogene
, vol.17
, pp. 1061-1068
-
-
Birch, J.M.1
Blair, V.2
Kelsey, A.M.3
Evans, D.G.4
Harris, M.5
Tricker, K.J.6
Varley, J.M.7
-
2
-
-
0142157701
-
Li-Fraumeni and related syndromes: correlation between tumor type, family structure, and TP53 genotype
-
Olivier M., Goldgar D.E., Sodha N., Ohgaki H., Kleihues P., Hainaut P., Eeles R.A. Li-Fraumeni and related syndromes: correlation between tumor type, family structure, and TP53 genotype. Cancer Res. 2003, 63:6643-6650.
-
(2003)
Cancer Res.
, vol.63
, pp. 6643-6650
-
-
Olivier, M.1
Goldgar, D.E.2
Sodha, N.3
Ohgaki, H.4
Kleihues, P.5
Hainaut, P.6
Eeles, R.A.7
-
3
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein B., Kinzler K.W. Cancer genes and the pathways they control. Nat. Med. 2004, 10:789-799.
-
(2004)
Nat. Med.
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
4
-
-
0024382760
-
The p53 proto-oncogene can act as a suppressor of transformation
-
Finlay C.A., Hinds P.W., Levine A.J. The p53 proto-oncogene can act as a suppressor of transformation. Cell 1989, 57:1083-1093.
-
(1989)
Cell
, vol.57
, pp. 1083-1093
-
-
Finlay, C.A.1
Hinds, P.W.2
Levine, A.J.3
-
5
-
-
0842346437
-
Principles of tumor suppression
-
Sherr C.J. Principles of tumor suppression. Cell 2004, 116:235-246.
-
(2004)
Cell
, vol.116
, pp. 235-246
-
-
Sherr, C.J.1
-
8
-
-
0036219608
-
Therapeutic exploitation of the p53 pathway
-
Lane D.P., Lain S. Therapeutic exploitation of the p53 pathway. Trends Mol. Med. 2002, 8:S38-42.
-
(2002)
Trends Mol. Med.
, vol.8
-
-
Lane, D.P.1
Lain, S.2
-
9
-
-
77956876340
-
The cell death machinery governed by the p53 tumor suppressor in response to DNA damage
-
Yoshida K., Miki Y. The cell death machinery governed by the p53 tumor suppressor in response to DNA damage. Cancer Sci. 2010, 101:831-835.
-
(2010)
Cancer Sci.
, vol.101
, pp. 831-835
-
-
Yoshida, K.1
Miki, Y.2
-
10
-
-
46049090743
-
Nuclear trafficking of pro-apoptotic kinases in response to DNA damage
-
Yoshida K. Nuclear trafficking of pro-apoptotic kinases in response to DNA damage. Trends Mol. Med. 2008, 14:305-313.
-
(2008)
Trends Mol. Med.
, vol.14
, pp. 305-313
-
-
Yoshida, K.1
-
11
-
-
0027496935
-
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
-
Harper J.W., Adami G.R., Wei N., Keyomarsi K., Elledge S.J. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 1993, 75:805-816.
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.W.1
Adami, G.R.2
Wei, N.3
Keyomarsi, K.4
Elledge, S.J.5
-
12
-
-
0027717617
-
P21 is a universal inhibitor of cyclin kinases
-
Xiong Y., Hannon G.J., Zhang H., Casso D., Kobayashi R., Beach D. p21 is a universal inhibitor of cyclin kinases. Nature 1993, 366:701-704.
-
(1993)
Nature
, vol.366
, pp. 701-704
-
-
Xiong, Y.1
Hannon, G.J.2
Zhang, H.3
Casso, D.4
Kobayashi, R.5
Beach, D.6
-
13
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
el-Deiry W.S., Tokino T., Velculescu V.E., Levy D.B., Parsons R., Trent J.M., Lin D., Mercer W.E., Kinzler K.W., Vogelstein B. WAF1, a potential mediator of p53 tumor suppression. Cell 1993, 75:817-825.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
el-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
14
-
-
0031310665
-
14-3-3 sigma is a p53-regulated inhibitor of G2/M progression
-
Hermeking H., Lengauer C., Polyak K., He T.C., Zhang L., Thiagalingam S., Kinzler K.W., Vogelstein B. 14-3-3 sigma is a p53-regulated inhibitor of G2/M progression. Mol. Cell 1997, 1:3-11.
-
(1997)
Mol. Cell
, vol.1
, pp. 3-11
-
-
Hermeking, H.1
Lengauer, C.2
Polyak, K.3
He, T.C.4
Zhang, L.5
Thiagalingam, S.6
Kinzler, K.W.7
Vogelstein, B.8
-
15
-
-
0034508217
-
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues
-
Lindsten T., Ross A.J., King A., Zong W.X., Rathmell J.C., Shiels H.A., Ulrich E., Waymire K.G., Mahar P., Frauwirth K., Chen Y., Wei M., Eng V.M., Adelman D.M., Simon M.C., Ma A., Golden J.A., Evan G., Korsmeyer S.J., MacGregor G.R., Thompson C.B. The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. Mol. Cell 2000, 6:1389-1399.
-
(2000)
Mol. Cell
, vol.6
, pp. 1389-1399
-
-
Lindsten, T.1
Ross, A.J.2
King, A.3
Zong, W.X.4
Rathmell, J.C.5
Shiels, H.A.6
Ulrich, E.7
Waymire, K.G.8
Mahar, P.9
Frauwirth, K.10
Chen, Y.11
Wei, M.12
Eng, V.M.13
Adelman, D.M.14
Simon, M.C.15
Ma, A.16
Golden, J.A.17
Evan, G.18
Korsmeyer, S.J.19
MacGregor, G.R.20
Thompson, C.B.21
more..
-
16
-
-
0034707047
-
The DNA damage response: putting checkpoints in perspective
-
Zhou B.B., Elledge S.J. The DNA damage response: putting checkpoints in perspective. Nature 2000, 408:433-439.
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
-
17
-
-
33744974524
-
P53 and its downstream proteins as molecular targets of cancer
-
Sun Y. p53 and its downstream proteins as molecular targets of cancer. Mol. Carcinog. 2006, 45:409-415.
-
(2006)
Mol. Carcinog.
, vol.45
, pp. 409-415
-
-
Sun, Y.1
-
18
-
-
0038751837
-
Transcriptional repression mediated by the p53 tumour suppressor
-
Ho J., Benchimol S. Transcriptional repression mediated by the p53 tumour suppressor. Cell Death Differ. 2003, 10:404-408.
-
(2003)
Cell Death Differ.
, vol.10
, pp. 404-408
-
-
Ho, J.1
Benchimol, S.2
-
19
-
-
72549085096
-
Transcription-independent p53 apoptosis: an alternative route to death
-
Speidel D. Transcription-independent p53 apoptosis: an alternative route to death. Trends Cell Biol. 2010, 20:14-24.
-
(2010)
Trends Cell Biol.
, vol.20
, pp. 14-24
-
-
Speidel, D.1
-
20
-
-
1142299539
-
Isolation of p53-target genes and their functional analysis
-
Nakamura Y. Isolation of p53-target genes and their functional analysis. Cancer Sci. 2004, 95:7-11.
-
(2004)
Cancer Sci.
, vol.95
, pp. 7-11
-
-
Nakamura, Y.1
-
21
-
-
0030941458
-
P53, the cellular gatekeeper for growth and division
-
Levine A.J. p53, the cellular gatekeeper for growth and division. Cell 1997, 88:323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
22
-
-
33847350861
-
DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage
-
Taira N., Nihira K., Yamaguchi T., Miki Y., Yoshida K. DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage. Mol. Cell 2007, 25:725-738.
-
(2007)
Mol. Cell
, vol.25
, pp. 725-738
-
-
Taira, N.1
Nihira, K.2
Yamaguchi, T.3
Miki, Y.4
Yoshida, K.5
-
23
-
-
0242522206
-
Regulation of apoptosis by Bcl-2 family proteins
-
Burlacu A. Regulation of apoptosis by Bcl-2 family proteins. J. Cell. Mol. Med. 2003, 7:249-257.
-
(2003)
J. Cell. Mol. Med.
, vol.7
, pp. 249-257
-
-
Burlacu, A.1
-
24
-
-
85006263913
-
BID regulation by p53 contributes to chemosensitivity
-
Sax J.K., Fei P., Murphy M.E., Bernhard E., Korsmeyer S.J., El-Deiry W.S. BID regulation by p53 contributes to chemosensitivity. Nat. Cell Biol. 2002, 4:842-849.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 842-849
-
-
Sax, J.K.1
Fei, P.2
Murphy, M.E.3
Bernhard, E.4
Korsmeyer, S.J.5
El-Deiry, W.S.6
-
25
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
Oda E., Ohki R., Murasawa H., Nemoto J., Shibue T., Yamashita T., Tokino T., Taniguchi T., Tanaka N. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 2000, 288:1053-1058.
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
26
-
-
0035265686
-
PUMA, a novel proapoptotic gene, is induced by p53
-
Nakano K., Vousden K.H. PUMA, a novel proapoptotic gene, is induced by p53. Mol. Cell 2001, 7:683-694.
-
(2001)
Mol. Cell
, vol.7
, pp. 683-694
-
-
Nakano, K.1
Vousden, K.H.2
-
27
-
-
0036674617
-
Live or let die: the cell's response to p53
-
Vousden K.H., Lu X. Live or let die: the cell's response to p53. Nat. Rev. Cancer 2002, 2:594-604.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
28
-
-
0030445491
-
Variable subcellular localization of a neuron-specific protein during NTera 2 differentiation into post-mitotic human neurons
-
Carlock L., Vo T., Lorincz M., Walker P.D., Bessert D., Wisniewski D., Dunbar J.C. Variable subcellular localization of a neuron-specific protein during NTera 2 differentiation into post-mitotic human neurons. Brain Res. Mol. Brain Res. 1996, 42:202-212.
-
(1996)
Brain Res. Mol. Brain Res.
, vol.42
, pp. 202-212
-
-
Carlock, L.1
Vo, T.2
Lorincz, M.3
Walker, P.D.4
Bessert, D.5
Wisniewski, D.6
Dunbar, J.C.7
-
29
-
-
0037166940
-
Modulation of receptor cycling by neuron-enriched endosomal protein of 21 kD
-
Steiner P., Sarria J.C., Glauser L., Magnin S., Catsicas S., Hirling H. Modulation of receptor cycling by neuron-enriched endosomal protein of 21 kD. J. Cell Biol. 2002, 157:1197-1209.
-
(2002)
J. Cell Biol.
, vol.157
, pp. 1197-1209
-
-
Steiner, P.1
Sarria, J.C.2
Glauser, L.3
Magnin, S.4
Catsicas, S.5
Hirling, H.6
-
30
-
-
4143144446
-
Crucial role of neuron-enriched endosomal protein of 21kDa in sorting between degradation and recycling of internalized G-protein-coupled receptors
-
Debaigt C., Hirling H., Steiner P., Vincent J.P., Mazella J. Crucial role of neuron-enriched endosomal protein of 21kDa in sorting between degradation and recycling of internalized G-protein-coupled receptors. J. Biol. Chem. 2004, 279:35687-35691.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 35687-35691
-
-
Debaigt, C.1
Hirling, H.2
Steiner, P.3
Vincent, J.P.4
Mazella, J.5
-
31
-
-
2542442501
-
AMPA receptor regulation mechanisms: future target for safer neuroprotective drugs
-
Jayakar S.S., Dikshit M. AMPA receptor regulation mechanisms: future target for safer neuroprotective drugs. Int. J. Neurosci. 2004, 114:695-734.
-
(2004)
Int. J. Neurosci.
, vol.114
, pp. 695-734
-
-
Jayakar, S.S.1
Dikshit, M.2
-
32
-
-
30544439756
-
Interactions between NEEP21, GRIP1 and GluR2 regulate sorting and recycling of the glutamate receptor subunit GluR2
-
Steiner P., Alberi S., Kulangara K., Yersin A., Sarria J.C., Regulier E., Kasas S., Dietler G., Muller D., Catsicas S., Hirling H. Interactions between NEEP21, GRIP1 and GluR2 regulate sorting and recycling of the glutamate receptor subunit GluR2. EMBO J. 2005, 24:2873-2884.
-
(2005)
EMBO J.
, vol.24
, pp. 2873-2884
-
-
Steiner, P.1
Alberi, S.2
Kulangara, K.3
Yersin, A.4
Sarria, J.C.5
Regulier, E.6
Kasas, S.7
Dietler, G.8
Muller, D.9
Catsicas, S.10
Hirling, H.11
-
33
-
-
58149464317
-
Neuronal enriched endosomal protein of 21kDa colocalizes with glutamate receptor subunit GLUR2/3 at the postsynaptic membrane
-
Utvik J.K., Haglerod C., Mylonakou M.N., Holen T., Kropf M., Hirling H., Skare O., Laake P., Ottersen O.P., Haug F.M., Davanger S. Neuronal enriched endosomal protein of 21kDa colocalizes with glutamate receptor subunit GLUR2/3 at the postsynaptic membrane. Neuroscience 2009, 158:96-104.
-
(2009)
Neuroscience
, vol.158
, pp. 96-104
-
-
Utvik, J.K.1
Haglerod, C.2
Mylonakou, M.N.3
Holen, T.4
Kropf, M.5
Hirling, H.6
Skare, O.7
Laake, P.8
Ottersen, O.P.9
Haug, F.M.10
Davanger, S.11
-
34
-
-
19444363666
-
The endosomal protein NEEP21 regulates AMPA receptor-mediated synaptic transmission and plasticity in the hippocampus
-
Alberi S., Boda B., Steiner P., Nikonenko I., Hirling H., Muller D. The endosomal protein NEEP21 regulates AMPA receptor-mediated synaptic transmission and plasticity in the hippocampus. Mol. Cell. Neurosci. 2005, 29:313-319.
-
(2005)
Mol. Cell. Neurosci.
, vol.29
, pp. 313-319
-
-
Alberi, S.1
Boda, B.2
Steiner, P.3
Nikonenko, I.4
Hirling, H.5
Muller, D.6
-
35
-
-
34047262358
-
Phosphorylation of glutamate receptor interacting protein 1 regulates surface expression of glutamate receptors
-
Kulangara K., Kropf M., Glauser L., Magnin S., Alberi S., Yersin A., Hirling H. Phosphorylation of glutamate receptor interacting protein 1 regulates surface expression of glutamate receptors. J. Biol. Chem. 2007, 282:2395-2404.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 2395-2404
-
-
Kulangara, K.1
Kropf, M.2
Glauser, L.3
Magnin, S.4
Alberi, S.5
Yersin, A.6
Hirling, H.7
-
36
-
-
14744301343
-
JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage
-
Yoshida K., Yamaguchi T., Natsume T., Kufe D., Miki Y. JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage. Nat. Cell Biol. 2005, 7:278-285.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 278-285
-
-
Yoshida, K.1
Yamaguchi, T.2
Natsume, T.3
Kufe, D.4
Miki, Y.5
-
37
-
-
0038237433
-
Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9
-
Yoshida K., Wang H.G., Miki Y., Kufe D. Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9. EMBO J. 2003, 22:1431-1441.
-
(2003)
EMBO J.
, vol.22
, pp. 1431-1441
-
-
Yoshida, K.1
Wang, H.G.2
Miki, Y.3
Kufe, D.4
-
38
-
-
33646229039
-
Protein kinase C delta regulates Ser46 phosphorylation of p53 tumor suppressor in the apoptotic response to DNA damage
-
Yoshida K., Liu H., Miki Y. Protein kinase C delta regulates Ser46 phosphorylation of p53 tumor suppressor in the apoptotic response to DNA damage. J. Biol. Chem. 2006, 281:5734-5740.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 5734-5740
-
-
Yoshida, K.1
Liu, H.2
Miki, Y.3
-
39
-
-
34147163862
-
Identification of a predictive gene expression signature of cervical lymph node metastasis in oral squamous cell carcinoma
-
Nguyen S.T., Hasegawa S., Tsuda H., Tomioka H., Ushijima M., Noda M., Omura K., Miki Y. Identification of a predictive gene expression signature of cervical lymph node metastasis in oral squamous cell carcinoma. Cancer Sci. 2007, 98:740-746.
-
(2007)
Cancer Sci.
, vol.98
, pp. 740-746
-
-
Nguyen, S.T.1
Hasegawa, S.2
Tsuda, H.3
Tomioka, H.4
Ushijima, M.5
Noda, M.6
Omura, K.7
Miki, Y.8
-
40
-
-
25444517056
-
MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes
-
Marinescu V.D., Kohane I.S., Riva A. MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes. BMC Bioinform. 2005, 6:79.
-
(2005)
BMC Bioinform.
, vol.6
, pp. 79
-
-
Marinescu, V.D.1
Kohane, I.S.2
Riva, A.3
-
41
-
-
0029778556
-
Signal-mediated sorting of membrane proteins between the endoplasmic reticulum and the golgi apparatus
-
Teasdale R.D., Jackson M.R. Signal-mediated sorting of membrane proteins between the endoplasmic reticulum and the golgi apparatus. Annu. Rev. Cell Dev. Biol. 1996, 12:27-54.
-
(1996)
Annu. Rev. Cell Dev. Biol.
, vol.12
, pp. 27-54
-
-
Teasdale, R.D.1
Jackson, M.R.2
-
42
-
-
1842843855
-
Roles of CHOP/GADD153 in endoplasmic reticulum stress
-
Oyadomari S., Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ. 2004, 11:381-389.
-
(2004)
Cell Death Differ.
, vol.11
, pp. 381-389
-
-
Oyadomari, S.1
Mori, M.2
-
43
-
-
0346250162
-
Regulation of apoptosis by endoplasmic reticulum pathways
-
Breckenridge D.G., Germain M., Mathai J.P., Nguyen M., Shore G.C. Regulation of apoptosis by endoplasmic reticulum pathways. Oncogene 2003, 22:8608-8618.
-
(2003)
Oncogene
, vol.22
, pp. 8608-8618
-
-
Breckenridge, D.G.1
Germain, M.2
Mathai, J.P.3
Nguyen, M.4
Shore, G.C.5
-
44
-
-
0037288692
-
Endoplasmic reticulum stress and diabetes mellitus
-
Araki E., Oyadomari S., Mori M. Endoplasmic reticulum stress and diabetes mellitus. Intern. Med. 2003, 42:7-14.
-
(2003)
Intern. Med.
, vol.42
, pp. 7-14
-
-
Araki, E.1
Oyadomari, S.2
Mori, M.3
-
45
-
-
21244462014
-
BH3-only BIK regulates BAX, BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death
-
Mathai J.P., Germain M., Shore G.C. BH3-only BIK regulates BAX, BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death. J. Biol. Chem. 2005, 280:23829-23836.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 23829-23836
-
-
Mathai, J.P.1
Germain, M.2
Shore, G.C.3
-
46
-
-
43249104789
-
Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway
-
Chen C.L., Lin C.F., Chang W.T., Huang W.C., Teng C.F., Lin Y.S. Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway. Blood 2008, 111:4365-4374.
-
(2008)
Blood
, vol.111
, pp. 4365-4374
-
-
Chen, C.L.1
Lin, C.F.2
Chang, W.T.3
Huang, W.C.4
Teng, C.F.5
Lin, Y.S.6
|