Identification of a predictive gene expression signature of cervical lymph node metastasis in oral squamous cell carcinoma

Cancer Science

Volumn 98, Issue 5, 2007, Pages 740-746

  Nguyen, Su Tien ^a   Hasegawa, Shogo ^a   Tsuda, Hitoshi ^b   Tomioka, Hirofumi ^a   Ushijima, Masaru ^c   Noda, Masaki ^a   Omura, Ken ^a   Miki, Yoshio ^a,d  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^c CANCER CHEMOTHERAPY CENTER   (Japan)

^d CANCER INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYCYTIDINE PHOSPHATE DEAMINASE; INTERLEUKIN 15; PARATHYROID HORMONE RELATED PROTEIN; RNA; THROMBOMODULIN;

ADULT; AGED; ARTICLE; CERVICAL LYMPH NODE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC ERROR; DIAGNOSTIC VALUE; DNA MICROARRAY; FEMALE; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENETIC ALGORITHM; HUMAN; HUMAN TISSUE; LASER CAPTURE MICRODISSECTION; LYMPH NODE METASTASIS; MALE; MOUTH CARCINOMA; NUCLEOTIDE SEQUENCE; ORAL SURGERY; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SQUAMOUS CELL CARCINOMA; UNINDEXED SEQUENCE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CLUSTER ANALYSIS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERLEUKIN-15; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MOUTH NEOPLASMS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR MARKERS, BIOLOGICAL;

EID: 34147163862     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2007.00454.x     Document Type: Article

References (16)

1. Jones AS, Phillips DE, Helliwell TR, Roland NJ. Occult node metastases in head and neck squamous carcinoma. Eur Arch Otorhinolaryngol 1993; 250: 446-9.
2. Genden EM, Ferlito A, Shaha AR et al. Complications of neck dissection. Acta Otolaryngol 2003; 123: 795-801.
3. Mueller O, Lightfoot S, Schroeder A. RNA integrity number (RIN) standardization of RNA quality control. Agilent Application Note, May 1 2004. Publication no. 5989-1165EN. Available from URL: http://www.gene-quantification.de/RIN.pdf
4. Imbeaud S, Graudens E, Boulanger V et al. Towards standardization of RNA quality assessment using user-independent classifiers of microcapillary electrophoresis traces. Nucleic Acids Res 2005; 33: E56.
5. Lee J, Hever A, Willhite D, Zlotnik A, Hevezi P. Effects of RNA degradation on gene expression analysis of human postmortem tissues. FASEB J 2005; 19: 1356-8.
6. Technical note, GeneChip Eukaryotic Small Sample Target Labeling Assay Version II. Available from URL: http://genomics.msu.edu/RTSF/ small_sample_labeling.pdf
7. Irizarry RA, Bolstad BM, Collin F, Cope LM, Hobbs B, Speed TP. Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res 2003; 31: E15.
8. Li J, Spletter ML, Johnson JA. Dissecting tBHQ induced ARE-driven gene expression through long and short oligonucleotide arrays. Physiol Genomics 2005; 21: 43-58.
9. Irizarry RA, Hobbs B, Collin F et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 2003; 4: 249-64.
10. Millenaar FF, Okyere J, May ST, van Zanten M, Voesenek LA, Peeters AJ. How to decide? Different methods of calculating gene expression from short oligonucleotide array data will give different results. BMC Bioinformatics 2006; 7: 137.
11. Freund Y, Schapire RE. A short introduction to boosting. J. Japan. Soc. Artif. Intel. 1999; 14: 771-80.
12. Ginzinger DG. Gene quantification using real-time quantitative PCR: An emerging technology hits the mainstream. Exp Hematol 2002; 30: 503-12.
13. Kuniyasu H, Ohmori H, Sasaki T et al. Production of interleukin 15 by human colon cancer cells is associated with induction of mucosal hyperplasia, angiogenesis, and metastasis. Clin Cancer Res 2003; 9: 4802-10.
14. Kuniyasu H, Oue N, Nakae D et al. Interleukin-15 expression is associated with malignant potential in colon cancer cells. Pathobiology 2001; 69: 86-95.
15. Shen X, Qian L, Falzon M. PTH-related protein enhances MCF-7 breast cancer cell adhesion, migration, and invasion via an intracrine pathway. Exp Cell Res 2004; 294: 420-33.
16. Shen X, Falzon M. PTH-related protein modulates PC-3 prostate cancer cell adhesion and integrin subunit profile. Mol Cell Endocrinol 2003; 199: 165-77.