-
1
-
-
0030678549
-
Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation
-
10.1016/S0092-8674(00)80257-3, 9182762
-
Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 1997, 89:747-754. 10.1016/S0092-8674(00)80257-3, 9182762.
-
(1997)
Cell
, vol.89
, pp. 747-754
-
-
Ducy, P.1
Zhang, R.2
Geoffroy, V.3
Ridall, A.L.4
Karsenty, G.5
-
2
-
-
2942548983
-
The Runx genes: lineage-specific oncogenes and tumor suppressors
-
10.1038/sj.onc.1207130, 15156187
-
Cameron ER, Neil JC. The Runx genes: lineage-specific oncogenes and tumor suppressors. Oncogene 2004, 23:4308-4314. 10.1038/sj.onc.1207130, 15156187.
-
(2004)
Oncogene
, vol.23
, pp. 4308-4314
-
-
Cameron, E.R.1
Neil, J.C.2
-
3
-
-
0031438731
-
The AML1 gene: a transcription factor involved in the pathogenesis of myeloid and lymphoid leukemias
-
Lo Coco F, Pisegna S, Diverio D. The AML1 gene: a transcription factor involved in the pathogenesis of myeloid and lymphoid leukemias. Haematologica 1997, 82:364-370.
-
(1997)
Haematologica
, vol.82
, pp. 364-370
-
-
Lo Coco, F.1
Pisegna, S.2
Diverio, D.3
-
4
-
-
0038610795
-
Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis
-
10.1073/pnas.1232420100, 164656, 12796513
-
Woolf E, Xiao C, Fainaru O, Lotem J, Rosen D, Negreanu V, Bernstein Y, Goldenberg D, Brenner O, Berke G, et al. Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis. Proc Natl Acad Sci USA 2003, 100:7731-7736. 10.1073/pnas.1232420100, 164656, 12796513.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 7731-7736
-
-
Woolf, E.1
Xiao, C.2
Fainaru, O.3
Lotem, J.4
Rosen, D.5
Negreanu, V.6
Bernstein, Y.7
Goldenberg, D.8
Brenner, O.9
Berke, G.10
-
5
-
-
0030684749
-
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
-
10.1016/S0092-8674(00)80258-5, 9182763
-
Komori T, Yagi H, Nomura S, Yamaguchi A, Sasaki K, Deguchi K, Shimizu Y, Bronson RT, Gao YH, Inada M, et al. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 1997, 89:755-764. 10.1016/S0092-8674(00)80258-5, 9182763.
-
(1997)
Cell
, vol.89
, pp. 755-764
-
-
Komori, T.1
Yagi, H.2
Nomura, S.3
Yamaguchi, A.4
Sasaki, K.5
Deguchi, K.6
Shimizu, Y.7
Bronson, R.T.8
Gao, Y.H.9
Inada, M.10
-
6
-
-
0030666372
-
Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
-
10.1016/S0092-8674(00)80259-7, 9182764
-
Otto F, Thornell AP, Crompton T, Denzel A, Gilmour KC, Rosewell IR, Stamp GW, Beddington RS, Mundlos S, Olsen BR, et al. Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 1997, 89:765-771. 10.1016/S0092-8674(00)80259-7, 9182764.
-
(1997)
Cell
, vol.89
, pp. 765-771
-
-
Otto, F.1
Thornell, A.P.2
Crompton, T.3
Denzel, A.4
Gilmour, K.C.5
Rosewell, I.R.6
Stamp, G.W.7
Beddington, R.S.8
Mundlos, S.9
Olsen, B.R.10
-
7
-
-
18444406568
-
The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons
-
10.1093/emboj/cdf370, 125397, 12093746
-
Levanon D, Bettoun D, Harris-Cerruti C, Woolf E, Negreanu V, Eilam R, Bernstein Y, Goldenberg D, Xiao C, Fliegauf M, et al. The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons. Embo J 2002, 21:3454-3463. 10.1093/emboj/cdf370, 125397, 12093746.
-
(2002)
Embo J
, vol.21
, pp. 3454-3463
-
-
Levanon, D.1
Bettoun, D.2
Harris-Cerruti, C.3
Woolf, E.4
Negreanu, V.5
Eilam, R.6
Bernstein, Y.7
Goldenberg, D.8
Xiao, C.9
Fliegauf, M.10
-
8
-
-
2942659322
-
Oncogenic potential of the RUNX gene family: 'overview'
-
10.1038/sj.onc.1207755, 15156173
-
Ito Y. Oncogenic potential of the RUNX gene family: 'overview'. Oncogene 2004, 23:4198-4208. 10.1038/sj.onc.1207755, 15156173.
-
(2004)
Oncogene
, vol.23
, pp. 4198-4208
-
-
Ito, Y.1
-
9
-
-
2942580741
-
Tumor suppressor activity of RUNX3
-
10.1038/sj.onc.1207286, 15156190
-
Bae SC, Choi JK. Tumor suppressor activity of RUNX3. Oncogene 2004, 23:4336-4340. 10.1038/sj.onc.1207286, 15156190.
-
(2004)
Oncogene
, vol.23
, pp. 4336-4340
-
-
Bae, S.C.1
Choi, J.K.2
-
10
-
-
2942512933
-
Structure and regulated expression of mammalian RUNX genes
-
10.1038/sj.onc.1207670, 15156175
-
Levanon D, Groner Y. Structure and regulated expression of mammalian RUNX genes. Oncogene 2004, 23:4211-4219. 10.1038/sj.onc.1207670, 15156175.
-
(2004)
Oncogene
, vol.23
, pp. 4211-4219
-
-
Levanon, D.1
Groner, Y.2
-
11
-
-
1842455990
-
Frequent loss of RUNX3 expression by promoter hypermethylation in gastric carcinoma
-
10.1159/000076468, 15051926
-
Oshimo Y, Oue N, Mitani Y, Nakayama H, Kitadai Y, Yoshida K, Ito Y, Chayama K, Yasui W. Frequent loss of RUNX3 expression by promoter hypermethylation in gastric carcinoma. Pathobiology 2004, 71:137-143. 10.1159/000076468, 15051926.
-
(2004)
Pathobiology
, vol.71
, pp. 137-143
-
-
Oshimo, Y.1
Oue, N.2
Mitani, Y.3
Nakayama, H.4
Kitadai, Y.5
Yoshida, K.6
Ito, Y.7
Chayama, K.8
Yasui, W.9
-
12
-
-
24044458907
-
Myeloid maturation block by AML1-MTG16 is associated with Csf1r epigenetic downregulation
-
10.1038/sj.onc.1208651, 16007222
-
Rossetti S, Van Unen L, Touw IP, Hoogeveen AT, Sacchi N. Myeloid maturation block by AML1-MTG16 is associated with Csf1r epigenetic downregulation. Oncogene 2005, 24:5325-5332. 10.1038/sj.onc.1208651, 16007222.
-
(2005)
Oncogene
, vol.24
, pp. 5325-5332
-
-
Rossetti, S.1
Van Unen, L.2
Touw, I.P.3
Hoogeveen, A.T.4
Sacchi, N.5
-
13
-
-
37049024521
-
Runx2 disruption promotes immortalization and confers resistance to oncogene-induced senescence in primary murine fibroblasts
-
10.1158/0008-5472.CAN-07-3016, 2562449, 18056452
-
Kilbey A, Blyth K, Wotton S, Terry A, Jenkins A, Bell M, Hanlon L, Cameron ER, Neil JC. Runx2 disruption promotes immortalization and confers resistance to oncogene-induced senescence in primary murine fibroblasts. Cancer Res 2007, 67:11263-11271. 10.1158/0008-5472.CAN-07-3016, 2562449, 18056452.
-
(2007)
Cancer Res
, vol.67
, pp. 11263-11271
-
-
Kilbey, A.1
Blyth, K.2
Wotton, S.3
Terry, A.4
Jenkins, A.5
Bell, M.6
Hanlon, L.7
Cameron, E.R.8
Neil, J.C.9
-
14
-
-
38049155882
-
Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential
-
10.1073/pnas.0709650104, 2148388, 18077419
-
Zaidi SK, Pande S, Pratap J, Gaur T, Grigoriu S, Ali SA, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential. Proc Natl Acad Sci USA 2007, 104:19861-19866. 10.1073/pnas.0709650104, 2148388, 18077419.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19861-19866
-
-
Zaidi, S.K.1
Pande, S.2
Pratap, J.3
Gaur, T.4
Grigoriu, S.5
Ali, S.A.6
Stein, J.L.7
Lian, J.B.8
van Wijnen, A.J.9
Stein, G.S.10
-
15
-
-
20144371011
-
The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts
-
10.1074/jbc.M413665200, 2895256, 15781466
-
Galindo M, Pratap J, Young DW, Hovhannisyan H, Im HJ, Choi JY, Lian JB, Stein JL, Stein GS, van Wijnen AJ. The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts. J Biol Chem 2005, 280:20274-20285. 10.1074/jbc.M413665200, 2895256, 15781466.
-
(2005)
J Biol Chem
, vol.280
, pp. 20274-20285
-
-
Galindo, M.1
Pratap, J.2
Young, D.W.3
Hovhannisyan, H.4
Im, H.J.5
Choi, J.Y.6
Lian, J.B.7
Stein, J.L.8
Stein, G.S.9
van Wijnen, A.J.10
-
16
-
-
0141705433
-
Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts
-
Pratap J, Galindo M, Zaidi SK, Vradii D, Bhat BM, Robinson JA, Choi JY, Komori T, Stein JL, Lian JB, et al. Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts. Cancer Res 2003, 63:5357-5362.
-
(2003)
Cancer Res
, vol.63
, pp. 5357-5362
-
-
Pratap, J.1
Galindo, M.2
Zaidi, S.K.3
Vradii, D.4
Bhat, B.M.5
Robinson, J.A.6
Choi, J.Y.7
Komori, T.8
Stein, J.L.9
Lian, J.B.10
-
17
-
-
10344237022
-
Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma
-
10.1083/jcb.200409187, 2172443, 15583032
-
Thomas DM, Johnson SA, Sims NA, Trivett MK, Slavin JL, Rubin BP, Waring P, McArthur GA, Walkley CR, Holloway AJ, et al. Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma. J Cell Biol 2004, 167:925-934. 10.1083/jcb.200409187, 2172443, 15583032.
-
(2004)
J Cell Biol
, vol.167
, pp. 925-934
-
-
Thomas, D.M.1
Johnson, S.A.2
Sims, N.A.3
Trivett, M.K.4
Slavin, J.L.5
Rubin, B.P.6
Waring, P.7
McArthur, G.A.8
Walkley, C.R.9
Holloway, A.J.10
-
18
-
-
0035905751
-
Runx2: a novel oncogenic effector revealed by in vivo complementation and retroviral tagging
-
10.1038/sj.onc.1204090, 11313958
-
Blyth K, Terry A, Mackay N, Vaillant F, Bell M, Cameron ER, Neil JC, Stewart M. Runx2: a novel oncogenic effector revealed by in vivo complementation and retroviral tagging. Oncogene 2001, 20:295-302. 10.1038/sj.onc.1204090, 11313958.
-
(2001)
Oncogene
, vol.20
, pp. 295-302
-
-
Blyth, K.1
Terry, A.2
Mackay, N.3
Vaillant, F.4
Bell, M.5
Cameron, E.R.6
Neil, J.C.7
Stewart, M.8
-
19
-
-
18344372018
-
The RUNX genes: gain or loss of function in cancer
-
10.1038/nrc1607, 15864279
-
Blyth K, Cameron ER, Neil JC. The RUNX genes: gain or loss of function in cancer. Nat Rev Cancer 2005, 5:376-387. 10.1038/nrc1607, 15864279.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 376-387
-
-
Blyth, K.1
Cameron, E.R.2
Neil, J.C.3
-
20
-
-
33751197049
-
Regulation of osteoblast differentiation by transcription factors
-
10.1002/jcb.20958, 16795049
-
Komori T. Regulation of osteoblast differentiation by transcription factors. J Cell Biochem 2006, 99:1233-1239. 10.1002/jcb.20958, 16795049.
-
(2006)
J Cell Biochem
, vol.99
, pp. 1233-1239
-
-
Komori, T.1
-
21
-
-
0036186852
-
Mutations in the RUNX2 gene in patients with cleidocranial dysplasia
-
10.1002/humu.10043, 11857736
-
Otto F, Kanegane H, Mundlos S. Mutations in the RUNX2 gene in patients with cleidocranial dysplasia. Hum Mutat 2002, 19:209-216. 10.1002/humu.10043, 11857736.
-
(2002)
Hum Mutat
, vol.19
, pp. 209-216
-
-
Otto, F.1
Kanegane, H.2
Mundlos, S.3
-
22
-
-
76849112495
-
Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions
-
2820596, 19915614
-
Akech J, Wixted JJ, Bedard K, van der Deen M, Hussain S, Guise TA, van Wijnen AJ, Stein JL, Languino LR, Altieri DC, et al. Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions. Oncogene 2009, 811-821. 2820596, 19915614.
-
(2009)
Oncogene
, pp. 811-821
-
-
Akech, J.1
Wixted, J.J.2
Bedard, K.3
van der Deen, M.4
Hussain, S.5
Guise, T.A.6
van Wijnen, A.J.7
Stein, J.L.8
Languino, L.R.9
Altieri, D.C.10
-
23
-
-
0033153362
-
Osteomimetic properties of prostate cancer cells: a hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environment
-
10.1002/(SICI)1097-0045(19990601)39:4<246::AID-PROS5>3.0.CO;2-U, 10344214
-
Koeneman KS, Yeung F, Chung LW. Osteomimetic properties of prostate cancer cells: a hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environment. Prostate 1999, 39:246-261. 10.1002/(SICI)1097-0045(19990601)39:4<246::AID-PROS5>3.0.CO;2-U, 10344214.
-
(1999)
Prostate
, vol.39
, pp. 246-261
-
-
Koeneman, K.S.1
Yeung, F.2
Chung, L.W.3
-
24
-
-
67650369580
-
Suppression of androgen-independent prostate cancer cell aggressiveness by FTY720: validating Runx2 as a potential antimetastatic drug screening platform
-
10.1158/1078-0432.CCR-08-3157, 19509141
-
Chua CW, Chiu YT, Yuen HF, Chan KW, Man K, Wang X, Ling MT, Wong YC. Suppression of androgen-independent prostate cancer cell aggressiveness by FTY720: validating Runx2 as a potential antimetastatic drug screening platform. Clin Cancer Res 2009, 15:4322-4335. 10.1158/1078-0432.CCR-08-3157, 19509141.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4322-4335
-
-
Chua, C.W.1
Chiu, Y.T.2
Yuen, H.F.3
Chan, K.W.4
Man, K.5
Wang, X.6
Ling, M.T.7
Wong, Y.C.8
-
25
-
-
0035873861
-
Bone metastatic LNCaP-derivative C4-2B prostate cancer cell line mineralizes in vitro
-
10.1002/pros.1065, 11351351
-
Lin DL, Tarnowski CP, Zhang J, Dai J, Rohn E, Patel AH, Morris MD, Keller ET. Bone metastatic LNCaP-derivative C4-2B prostate cancer cell line mineralizes in vitro. Prostate 2001, 47:212-221. 10.1002/pros.1065, 11351351.
-
(2001)
Prostate
, vol.47
, pp. 212-221
-
-
Lin, D.L.1
Tarnowski, C.P.2
Zhang, J.3
Dai, J.4
Rohn, E.5
Patel, A.H.6
Morris, M.D.7
Keller, E.T.8
-
26
-
-
3042549099
-
Smad3 interacts with JunB and Cbfa1/Runx2 for transforming growth factor-beta1-stimulated collagenase-3 expression in human breast cancer cells
-
10.1074/jbc.M312870200, 15084595
-
Selvamurugan N, Kwok S, Partridge NC. Smad3 interacts with JunB and Cbfa1/Runx2 for transforming growth factor-beta1-stimulated collagenase-3 expression in human breast cancer cells. J Biol Chem 2004, 279:27764-27773. 10.1074/jbc.M312870200, 15084595.
-
(2004)
J Biol Chem
, vol.279
, pp. 27764-27773
-
-
Selvamurugan, N.1
Kwok, S.2
Partridge, N.C.3
-
27
-
-
75949085815
-
Runx2 regulates survivin expression in prostate cancer cells
-
10.1038/labinvest.2009.128, 2815261, 19949374
-
Lim M, Zhong C, Yang S, Bell AM, Cohen MB, Roy-Burman P. Runx2 regulates survivin expression in prostate cancer cells. Lab Invest 90:222-233. 10.1038/labinvest.2009.128, 2815261, 19949374.
-
Lab Invest
, vol.90
, pp. 222-233
-
-
Lim, M.1
Zhong, C.2
Yang, S.3
Bell, A.M.4
Cohen, M.B.5
Roy-Burman, P.6
-
28
-
-
25444473106
-
The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion
-
10.1128/MCB.25.19.8581-8591.2005, 1265732, 16166639
-
Pratap J, Javed A, Languino LR, van Wijnen AJ, Stein JL, Stein GS, Lian JB. The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion. Mol Cell Biol 2005, 25:8581-8591. 10.1128/MCB.25.19.8581-8591.2005, 1265732, 16166639.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8581-8591
-
-
Pratap, J.1
Javed, A.2
Languino, L.R.3
van Wijnen, A.J.4
Stein, J.L.5
Stein, G.S.6
Lian, J.B.7
-
29
-
-
0037843323
-
Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells
-
Barnes GL, Javed A, Waller SM, Kamal MH, Hebert KE, Hassan MQ, Bellahcene A, Van Wijnen AJ, Young MF, Lian JB, et al. Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells. Cancer Res 2003, 63:2631-2637.
-
(2003)
Cancer Res
, vol.63
, pp. 2631-2637
-
-
Barnes, G.L.1
Javed, A.2
Waller, S.M.3
Kamal, M.H.4
Hebert, K.E.5
Hassan, M.Q.6
Bellahcene, A.7
Van Wijnen, A.J.8
Young, M.F.9
Lian, J.B.10
-
30
-
-
0034914814
-
Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2
-
10.1016/S0925-4773(01)00428-2, 11472838
-
Zelzer E, Glotzer DJ, Hartmann C, Thomas D, Fukai N, Soker S, Olsen BR. Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2. Mech Dev 2001, 106:97-106. 10.1016/S0925-4773(01)00428-2, 11472838.
-
(2001)
Mech Dev
, vol.106
, pp. 97-106
-
-
Zelzer, E.1
Glotzer, D.J.2
Hartmann, C.3
Thomas, D.4
Fukai, N.5
Soker, S.6
Olsen, B.R.7
-
31
-
-
0036333736
-
High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage
-
10.1128/MCB.22.17.6222-6233.2002, 134019, 12167715
-
Geoffroy V, Kneissel M, Fournier B, Boyde A, Matthias P. High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage. Mol Cell Biol 2002, 22:6222-6233. 10.1128/MCB.22.17.6222-6233.2002, 134019, 12167715.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6222-6233
-
-
Geoffroy, V.1
Kneissel, M.2
Fournier, B.3
Boyde, A.4
Matthias, P.5
-
32
-
-
34447554463
-
Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency
-
10.1002/dvdy.21187, 17497678
-
Maruyama Z, Yoshida CA, Furuichi T, Amizuka N, Ito M, Fukuyama R, Miyazaki T, Kitaura H, Nakamura K, Fujita T, et al. Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency. Dev Dyn 2007, 236:1876-1890. 10.1002/dvdy.21187, 17497678.
-
(2007)
Dev Dyn
, vol.236
, pp. 1876-1890
-
-
Maruyama, Z.1
Yoshida, C.A.2
Furuichi, T.3
Amizuka, N.4
Ito, M.5
Fukuyama, R.6
Miyazaki, T.7
Kitaura, H.8
Nakamura, K.9
Fujita, T.10
-
33
-
-
0037169539
-
Regulation of human osteocalcin promoter in hormone-independent human prostate cancer cells
-
10.1074/jbc.M105947200, 11684680
-
Yeung F, Law WK, Yeh CH, Westendorf JJ, Zhang Y, Wang R, Kao C, Chung LW. Regulation of human osteocalcin promoter in hormone-independent human prostate cancer cells. J Biol Chem 2002, 277:2468-2476. 10.1074/jbc.M105947200, 11684680.
-
(2002)
J Biol Chem
, vol.277
, pp. 2468-2476
-
-
Yeung, F.1
Law, W.K.2
Yeh, C.H.3
Westendorf, J.J.4
Zhang, Y.5
Wang, R.6
Kao, C.7
Chung, L.W.8
-
34
-
-
70149098945
-
Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression
-
10.1158/0008-5472.CAN-09-1471, 2742766, 19690135
-
Pratap J, Imbalzano KM, Underwood JM, Cohet N, Gokul K, Akech J, van Wijnen AJ, Stein JL, Imbalzano AN, Nickerson JA, et al. Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression. Cancer Res 2009, 69:6807-6814. 10.1158/0008-5472.CAN-09-1471, 2742766, 19690135.
-
(2009)
Cancer Res
, vol.69
, pp. 6807-6814
-
-
Pratap, J.1
Imbalzano, K.M.2
Underwood, J.M.3
Cohet, N.4
Gokul, K.5
Akech, J.6
van Wijnen, A.J.7
Stein, J.L.8
Imbalzano, A.N.9
Nickerson, J.A.10
-
35
-
-
35348831090
-
Regulation and functional role of the Runt-related transcription factor-2 in pancreatic cancer
-
10.1038/sj.bjc.6603984, 2360444, 17876328
-
Kayed H, Jiang X, Keleg S, Jesnowski R, Giese T, Berger MR, Esposito I, Lohr M, Friess H, Kleeff J. Regulation and functional role of the Runt-related transcription factor-2 in pancreatic cancer. Br J Cancer 2007, 97:1106-1115. 10.1038/sj.bjc.6603984, 2360444, 17876328.
-
(2007)
Br J Cancer
, vol.97
, pp. 1106-1115
-
-
Kayed, H.1
Jiang, X.2
Keleg, S.3
Jesnowski, R.4
Giese, T.5
Berger, M.R.6
Esposito, I.7
Lohr, M.8
Friess, H.9
Kleeff, J.10
-
36
-
-
45149089581
-
Expression and function of Cbfa-1/Runx2 in thyroid papillary carcinoma cells
-
10.1210/jc.2007-2805, 18381576
-
Endo T, Ohta K, Kobayashi T. Expression and function of Cbfa-1/Runx2 in thyroid papillary carcinoma cells. J Clin Endocrinol Metab 2008, 93:2409-2412. 10.1210/jc.2007-2805, 18381576.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 2409-2412
-
-
Endo, T.1
Ohta, K.2
Kobayashi, T.3
-
37
-
-
0020638814
-
LNCaP model of human prostatic carcinoma
-
Horoszewicz JS, Leong SS, Kawinski E, Karr JP, Rosenthal H, Chu TM, Mirand EA, Murphy GP. LNCaP model of human prostatic carcinoma. Cancer Res 1983, 43:1809-1818.
-
(1983)
Cancer Res
, vol.43
, pp. 1809-1818
-
-
Horoszewicz, J.S.1
Leong, S.S.2
Kawinski, E.3
Karr, J.P.4
Rosenthal, H.5
Chu, T.M.6
Mirand, E.A.7
Murphy, G.P.8
-
38
-
-
0028321891
-
Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: role of bone stromal cells
-
10.1002/ijc.2910570319, 8169003
-
Wu HC, Hsieh JT, Gleave ME, Brown NM, Pathak S, Chung LW. Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: role of bone stromal cells. Int J Cancer 1994, 57:406-412. 10.1002/ijc.2910570319, 8169003.
-
(1994)
Int J Cancer
, vol.57
, pp. 406-412
-
-
Wu, H.C.1
Hsieh, J.T.2
Gleave, M.E.3
Brown, N.M.4
Pathak, S.5
Chung, L.W.6
-
39
-
-
33748758189
-
A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression
-
10.1073/pnas.0606179103, 1557799, 16945906
-
Shin KJ, Wall EA, Zavzavadjian JR, Santat LA, Liu J, Hwang JI, Rebres R, Roach T, Seaman W, Simon MI, Fraser ID. A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression. Proc Natl Acad Sci USA 2006, 103:13759-13764. 10.1073/pnas.0606179103, 1557799, 16945906.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 13759-13764
-
-
Shin, K.J.1
Wall, E.A.2
Zavzavadjian, J.R.3
Santat, L.A.4
Liu, J.5
Hwang, J.I.6
Rebres, R.7
Roach, T.8
Seaman, W.9
Simon, M.I.10
Fraser, I.D.11
-
40
-
-
0035831044
-
Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta
-
10.1016/S0092-8674(01)00271-9, 11257229
-
Tahirov TH, Inoue-Bungo T, Morii H, Fujikawa A, Sasaki M, Kimura K, Shiina M, Sato K, Kumasaka T, Yamamoto M, et al. Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta. Cell 2001, 104:755-767. 10.1016/S0092-8674(01)00271-9, 11257229.
-
(2001)
Cell
, vol.104
, pp. 755-767
-
-
Tahirov, T.H.1
Inoue-Bungo, T.2
Morii, H.3
Fujikawa, A.4
Sasaki, M.5
Kimura, K.6
Shiina, M.7
Sato, K.8
Kumasaka, T.9
Yamamoto, M.10
-
41
-
-
0035976775
-
Translational regulation is a control point in RUNX2/Cbfa1 gene expression
-
10.1006/bbrc.2001.6033, 11716520
-
Sudhakar S, Li Y, Katz MS, Elango N. Translational regulation is a control point in RUNX2/Cbfa1 gene expression. Biochem Biophys Res Commun 2001, 289:616-622. 10.1006/bbrc.2001.6033, 11716520.
-
(2001)
Biochem Biophys Res Commun
, vol.289
, pp. 616-622
-
-
Sudhakar, S.1
Li, Y.2
Katz, M.S.3
Elango, N.4
-
42
-
-
0028927556
-
Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene
-
230411, 7891679
-
Ducy P, Karsenty G. Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene. Mol Cell Biol 1995, 15:1858-1869. 230411, 7891679.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 1858-1869
-
-
Ducy, P.1
Karsenty, G.2
-
43
-
-
33748170578
-
Microarray analysis on Runx2-deficient mouse embryos reveals novel Runx2 functions and target genes during intramembranous and endochondral bone formation
-
10.1016/j.bone.2006.04.024, 16774856
-
Vaes BL, Ducy P, Sijbers AM, Hendriks JM, van Someren EP, de Jong NG, van den Heuvel ER, Olijve W, van Zoelen EJ, Dechering KJ. Microarray analysis on Runx2-deficient mouse embryos reveals novel Runx2 functions and target genes during intramembranous and endochondral bone formation. Bone 2006, 39:724-738. 10.1016/j.bone.2006.04.024, 16774856.
-
(2006)
Bone
, vol.39
, pp. 724-738
-
-
Vaes, B.L.1
Ducy, P.2
Sijbers, A.M.3
Hendriks, J.M.4
van Someren, E.P.5
de Jong, N.G.6
van den Heuvel, E.R.7
Olijve, W.8
van Zoelen, E.J.9
Dechering, K.J.10
-
44
-
-
13344259902
-
The transcriptional control of trunk neural crest induction, survival, and delamination
-
10.1016/j.devcel.2004.12.010, 15691760
-
Cheung M, Chaboissier MC, Mynett A, Hirst E, Schedl A, Briscoe J. The transcriptional control of trunk neural crest induction, survival, and delamination. Dev Cell 2005, 8:179-192. 10.1016/j.devcel.2004.12.010, 15691760.
-
(2005)
Dev Cell
, vol.8
, pp. 179-192
-
-
Cheung, M.1
Chaboissier, M.C.2
Mynett, A.3
Hirst, E.4
Schedl, A.5
Briscoe, J.6
-
45
-
-
62649098660
-
Lipocalin 2 promotes breast cancer progression
-
10.1073/pnas.0810617106, 2656179, 19237579
-
Yang J, Bielenberg DR, Rodig SJ, Doiron R, Clifton MC, Kung AL, Strong RK, Zurakowski D, Moses MA. Lipocalin 2 promotes breast cancer progression. Proc Natl Acad Sci USA 2009, 106:3913-3918. 10.1073/pnas.0810617106, 2656179, 19237579.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3913-3918
-
-
Yang, J.1
Bielenberg, D.R.2
Rodig, S.J.3
Doiron, R.4
Clifton, M.C.5
Kung, A.L.6
Strong, R.K.7
Zurakowski, D.8
Moses, M.A.9
-
46
-
-
0034677937
-
A novel aspartyl proteinase from apocrine epithelia and breast tumors
-
10.1074/jbc.275.11.7935, 10713110
-
Caputo E, Manco G, Mandrich L, Guardiola J. A novel aspartyl proteinase from apocrine epithelia and breast tumors. J Biol Chem 2000, 275:7935-7941. 10.1074/jbc.275.11.7935, 10713110.
-
(2000)
J Biol Chem
, vol.275
, pp. 7935-7941
-
-
Caputo, E.1
Manco, G.2
Mandrich, L.3
Guardiola, J.4
-
47
-
-
0019835973
-
Human prostatic gastricsinogen: the precursor of seminal fluid acid proteinase
-
10.1016/0003-9861(81)90158-2, 6794457
-
Chiang L, Contreras L, Chiang J, Ward PH. Human prostatic gastricsinogen: the precursor of seminal fluid acid proteinase. Arch Biochem Biophys 1981, 210:14-20. 10.1016/0003-9861(81)90158-2, 6794457.
-
(1981)
Arch Biochem Biophys
, vol.210
, pp. 14-20
-
-
Chiang, L.1
Contreras, L.2
Chiang, J.3
Ward, P.H.4
-
48
-
-
0032952304
-
CMAP: a novel cystatin-like gene involved in liver metastasis
-
Morita M, Yoshiuchi N, Arakawa H, Nishimura S. CMAP: a novel cystatin-like gene involved in liver metastasis. Cancer Res 1999, 59:151-158.
-
(1999)
Cancer Res
, vol.59
, pp. 151-158
-
-
Morita, M.1
Yoshiuchi, N.2
Arakawa, H.3
Nishimura, S.4
-
49
-
-
67349171584
-
Metastasis promoter S100A4 is a potentially valuable molecular target for cancer therapy
-
10.1016/j.canlet.2008.10.037, 19059703
-
Sherbet GV. Metastasis promoter S100A4 is a potentially valuable molecular target for cancer therapy. Cancer Lett 2009, 280:15-30. 10.1016/j.canlet.2008.10.037, 19059703.
-
(2009)
Cancer Lett
, vol.280
, pp. 15-30
-
-
Sherbet, G.V.1
-
50
-
-
77951884383
-
Functional interaction between Smad3 and S100A4 (metastatin-1) for TGF-beta-mediated cancer cell invasiveness
-
10.1042/BJ20090990, 20070253
-
Matsuura I, Lai CY, Chiang KN. Functional interaction between Smad3 and S100A4 (metastatin-1) for TGF-beta-mediated cancer cell invasiveness. Biochem J 2010, 426:327-335. 10.1042/BJ20090990, 20070253.
-
(2010)
Biochem J
, vol.426
, pp. 327-335
-
-
Matsuura, I.1
Lai, C.Y.2
Chiang, K.N.3
-
51
-
-
33645507413
-
Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stages of invadopodia formation and function
-
10.1158/0008-5472.CAN-05-2177, 16540652
-
Artym VV, Zhang Y, Seillier-Moiseiwitsch F, Yamada KM, Mueller SC. Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stages of invadopodia formation and function. Cancer Res 2006, 66:3034-3043. 10.1158/0008-5472.CAN-05-2177, 16540652.
-
(2006)
Cancer Res
, vol.66
, pp. 3034-3043
-
-
Artym, V.V.1
Zhang, Y.2
Seillier-Moiseiwitsch, F.3
Yamada, K.M.4
Mueller, S.C.5
-
52
-
-
33748328139
-
The matrix reorganized: extracellular matrix remodeling and integrin signaling
-
10.1016/j.ceb.2006.08.009, 16919434
-
Larsen M, Artym VV, Green JA, Yamada KM. The matrix reorganized: extracellular matrix remodeling and integrin signaling. Curr Opin Cell Biol 2006, 18:463-471. 10.1016/j.ceb.2006.08.009, 16919434.
-
(2006)
Curr Opin Cell Biol
, vol.18
, pp. 463-471
-
-
Larsen, M.1
Artym, V.V.2
Green, J.A.3
Yamada, K.M.4
-
53
-
-
64549159379
-
The cell migration molecule UNC-53/NAV2 is linked to the ARP2/3 complex by ABI-1
-
10.1242/dev.016816, 19168673
-
Schmidt KL, Marcus-Gueret N, Adeleye A, Webber J, Baillie D, Stringham EG. The cell migration molecule UNC-53/NAV2 is linked to the ARP2/3 complex by ABI-1. Development 2009, 136:563-574. 10.1242/dev.016816, 19168673.
-
(2009)
Development
, vol.136
, pp. 563-574
-
-
Schmidt, K.L.1
Marcus-Gueret, N.2
Adeleye, A.3
Webber, J.4
Baillie, D.5
Stringham, E.G.6
-
54
-
-
0037442787
-
Novel espin actin-bundling proteins are localized to Purkinje cell dendritic spines and bind the Src homology 3 adapter protein insulin receptor substrate p53
-
2854510, 12598619
-
Sekerkova G, Loomis PA, Changyaleket B, Zheng L, Eytan R, Chen B, Mugnaini E, Bartles JR. Novel espin actin-bundling proteins are localized to Purkinje cell dendritic spines and bind the Src homology 3 adapter protein insulin receptor substrate p53. J Neurosci 2003, 23:1310-1319. 2854510, 12598619.
-
(2003)
J Neurosci
, vol.23
, pp. 1310-1319
-
-
Sekerkova, G.1
Loomis, P.A.2
Changyaleket, B.3
Zheng, L.4
Eytan, R.5
Chen, B.6
Mugnaini, E.7
Bartles, J.R.8
-
55
-
-
33846785588
-
Microtubule-associated protein 1B, a growth-associated and phosphorylated scaffold protein
-
10.1016/j.brainresbull.2006.11.012, 17292797
-
Riederer BM. Microtubule-associated protein 1B, a growth-associated and phosphorylated scaffold protein. Brain Res Bull 2007, 71:541-558. 10.1016/j.brainresbull.2006.11.012, 17292797.
-
(2007)
Brain Res Bull
, vol.71
, pp. 541-558
-
-
Riederer, B.M.1
-
56
-
-
0037415614
-
EPLIN regulates actin dynamics by cross-linking and stabilizing filaments
-
10.1083/jcb.200212057, 2172667, 12566430
-
Maul RS, Song Y, Amann KJ, Gerbin SC, Pollard TD, Chang DD. EPLIN regulates actin dynamics by cross-linking and stabilizing filaments. J Cell Biol 2003, 160:399-407. 10.1083/jcb.200212057, 2172667, 12566430.
-
(2003)
J Cell Biol
, vol.160
, pp. 399-407
-
-
Maul, R.S.1
Song, Y.2
Amann, K.J.3
Gerbin, S.C.4
Pollard, T.D.5
Chang, D.D.6
-
57
-
-
3042710591
-
Regulation of cytoskeletal dynamics by actin-monomer-binding proteins
-
10.1016/j.tcb.2004.05.002, 15246432
-
Paavilainen VO, Bertling E, Falck S, Lappalainen P. Regulation of cytoskeletal dynamics by actin-monomer-binding proteins. Trends Cell Biol 2004, 14:386-394. 10.1016/j.tcb.2004.05.002, 15246432.
-
(2004)
Trends Cell Biol
, vol.14
, pp. 386-394
-
-
Paavilainen, V.O.1
Bertling, E.2
Falck, S.3
Lappalainen, P.4
-
58
-
-
67650349084
-
CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling
-
10.1182/blood-2008-12-196618, 19380869
-
Levoye A, Balabanian K, Baleux F, Bachelerie F, Lagane B. CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling. Blood 2009, 113:6085-6093. 10.1182/blood-2008-12-196618, 19380869.
-
(2009)
Blood
, vol.113
, pp. 6085-6093
-
-
Levoye, A.1
Balabanian, K.2
Baleux, F.3
Bachelerie, F.4
Lagane, B.5
-
59
-
-
39549122204
-
Essential but differential role for CXCR4 and CXCR7 in the therapeutic homing of human renal progenitor cells
-
10.1084/jem.20071903, 2271008, 18268039
-
Mazzinghi B, Ronconi E, Lazzeri E, Sagrinati C, Ballerini L, Angelotti ML, Parente E, Mancina R, Netti GS, Becherucci F, et al. Essential but differential role for CXCR4 and CXCR7 in the therapeutic homing of human renal progenitor cells. J Exp Med 2008, 205:479-490. 10.1084/jem.20071903, 2271008, 18268039.
-
(2008)
J Exp Med
, vol.205
, pp. 479-490
-
-
Mazzinghi, B.1
Ronconi, E.2
Lazzeri, E.3
Sagrinati, C.4
Ballerini, L.5
Angelotti, M.L.6
Parente, E.7
Mancina, R.8
Netti, G.S.9
Becherucci, F.10
-
60
-
-
33947310596
-
Stroma-derived factor (SDF-1/CXCL12) and human tumor pathogenesis
-
10.1152/ajpcell.00406.2006, 16943240
-
Kryczek I, Wei S, Keller E, Liu R, Zou W. Stroma-derived factor (SDF-1/CXCL12) and human tumor pathogenesis. Am J Physiol Cell Physiol 2007, 292:C987-995. 10.1152/ajpcell.00406.2006, 16943240.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
-
-
Kryczek, I.1
Wei, S.2
Keller, E.3
Liu, R.4
Zou, W.5
-
61
-
-
10044284415
-
CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion
-
10.1038/labinvest.3700181, 15467730
-
Singh S, Singh UP, Grizzle WE, Lillard JW. CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion. Lab Invest 2004, 84:1666-1676. 10.1038/labinvest.3700181, 15467730.
-
(2004)
Lab Invest
, vol.84
, pp. 1666-1676
-
-
Singh, S.1
Singh, U.P.2
Grizzle, W.E.3
Lillard, J.W.4
-
62
-
-
19944431949
-
CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers
-
Kryczek I, Lange A, Mottram P, Alvarez X, Cheng P, Hogan M, Moons L, Wei S, Zou L, Machelon V, et al. CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers. Cancer Res 2005, 65:465-472.
-
(2005)
Cancer Res
, vol.65
, pp. 465-472
-
-
Kryczek, I.1
Lange, A.2
Mottram, P.3
Alvarez, X.4
Cheng, P.5
Hogan, M.6
Moons, L.7
Wei, S.8
Zou, L.9
Machelon, V.10
-
63
-
-
0037085938
-
Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone
-
Taichman RS, Cooper C, Keller ET, Pienta KJ, Taichman NS, McCauley LK. Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone. Cancer Res 2002, 62:1832-1837.
-
(2002)
Cancer Res
, vol.62
, pp. 1832-1837
-
-
Taichman, R.S.1
Cooper, C.2
Keller, E.T.3
Pienta, K.J.4
Taichman, N.S.5
McCauley, L.K.6
-
64
-
-
0042432054
-
Long-term hematopoietic stem cells require stromal cell-derived factor-1 for colonizing bone marrow during ontogeny
-
10.1016/S1074-7613(03)00201-2, 12932359
-
Ara T, Tokoyoda K, Sugiyama T, Egawa T, Kawabata K, Nagasawa T. Long-term hematopoietic stem cells require stromal cell-derived factor-1 for colonizing bone marrow during ontogeny. Immunity 2003, 19:257-267. 10.1016/S1074-7613(03)00201-2, 12932359.
-
(2003)
Immunity
, vol.19
, pp. 257-267
-
-
Ara, T.1
Tokoyoda, K.2
Sugiyama, T.3
Egawa, T.4
Kawabata, K.5
Nagasawa, T.6
-
65
-
-
0033524834
-
Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4
-
10.1126/science.283.5403.845, 9933168
-
Peled A, Petit I, Kollet O, Magid M, Ponomaryov T, Byk T, Nagler A, Ben-Hur H, Many A, Shultz L, et al. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science 1999, 283:845-848. 10.1126/science.283.5403.845, 9933168.
-
(1999)
Science
, vol.283
, pp. 845-848
-
-
Peled, A.1
Petit, I.2
Kollet, O.3
Magid, M.4
Ponomaryov, T.5
Byk, T.6
Nagler, A.7
Ben-Hur, H.8
Many, A.9
Shultz, L.10
-
66
-
-
0032126225
-
Prognostic value of bone sialoprotein expression in clinically localized human prostate cancer
-
10.1093/jnci/90.13.1000, 9665149
-
Waltregny D, Bellahcene A, Van Riet I, Fisher LW, Young M, Fernandez P, Dewe W, de Leval J, Castronovo V. Prognostic value of bone sialoprotein expression in clinically localized human prostate cancer. J Natl Cancer Inst 1998, 90:1000-1008. 10.1093/jnci/90.13.1000, 9665149.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1000-1008
-
-
Waltregny, D.1
Bellahcene, A.2
Van Riet, I.3
Fisher, L.W.4
Young, M.5
Fernandez, P.6
Dewe, W.7
de Leval, J.8
Castronovo, V.9
-
67
-
-
0034055420
-
Increased expression of bone sialoprotein in bone metastases compared with visceral metastases in human breast and prostate cancers
-
10.1359/jbmr.2000.15.5.834, 10804012
-
Waltregny D, Bellahcene A, de Leval X, Florkin B, Weidle U, Castronovo V. Increased expression of bone sialoprotein in bone metastases compared with visceral metastases in human breast and prostate cancers. J Bone Miner Res 2000, 15:834-843. 10.1359/jbmr.2000.15.5.834, 10804012.
-
(2000)
J Bone Miner Res
, vol.15
, pp. 834-843
-
-
Waltregny, D.1
Bellahcene, A.2
de Leval, X.3
Florkin, B.4
Weidle, U.5
Castronovo, V.6
-
68
-
-
1542561305
-
Over-expression of bone sialoprotein enhances bone metastasis of human breast cancer cells in a mouse model
-
Zhang JH, Tang J, Wang J, Ma W, Zheng W, Yoneda T, Chen J. Over-expression of bone sialoprotein enhances bone metastasis of human breast cancer cells in a mouse model. Int J Oncol 2003, 23:1043-1048.
-
(2003)
Int J Oncol
, vol.23
, pp. 1043-1048
-
-
Zhang, J.H.1
Tang, J.2
Wang, J.3
Ma, W.4
Zheng, W.5
Yoneda, T.6
Chen, J.7
-
69
-
-
4043064387
-
Comparison of 10 serum bone turnover markers in prostate carcinoma patients with bone metastatic spread: diagnostic and prognostic implications
-
10.1002/ijc.20314, 15252851
-
Jung K, Lein M, Stephan C, Von Hosslin K, Semjonow A, Sinha P, Loening SA, Schnorr D. Comparison of 10 serum bone turnover markers in prostate carcinoma patients with bone metastatic spread: diagnostic and prognostic implications. Int J Cancer 2004, 111:783-791. 10.1002/ijc.20314, 15252851.
-
(2004)
Int J Cancer
, vol.111
, pp. 783-791
-
-
Jung, K.1
Lein, M.2
Stephan, C.3
Von Hosslin, K.4
Semjonow, A.5
Sinha, P.6
Loening, S.A.7
Schnorr, D.8
-
70
-
-
0035740253
-
Prostate carcinoma skeletal metastases: cross-talk between tumor and bone
-
10.1023/A:1015599831232, 12085970
-
Keller ET, Zhang J, Cooper CR, Smith PC, McCauley LK, Pienta KJ, Taichman RS. Prostate carcinoma skeletal metastases: cross-talk between tumor and bone. Cancer Metastasis Rev 2001, 20:333-349. 10.1023/A:1015599831232, 12085970.
-
(2001)
Cancer Metastasis Rev
, vol.20
, pp. 333-349
-
-
Keller, E.T.1
Zhang, J.2
Cooper, C.R.3
Smith, P.C.4
McCauley, L.K.5
Pienta, K.J.6
Taichman, R.S.7
-
71
-
-
3142777998
-
AML1/Runx1 recruits calcineurin to regulate granulocyte macrophage colony-stimulating factor by Ets1 activation
-
10.1074/jbc.M403173200, 15123671
-
Liu H, Holm M, Xie XQ, Wolf-Watz M, Grundstrom T. AML1/Runx1 recruits calcineurin to regulate granulocyte macrophage colony-stimulating factor by Ets1 activation. J Biol Chem 2004, 279:29398-29408. 10.1074/jbc.M403173200, 15123671.
-
(2004)
J Biol Chem
, vol.279
, pp. 29398-29408
-
-
Liu, H.1
Holm, M.2
Xie, X.Q.3
Wolf-Watz, M.4
Grundstrom, T.5
-
72
-
-
33846049299
-
NF-kappaB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF
-
10.1038/nm1519, 17159986
-
Park BK, Zhang H, Zeng Q, Dai J, Keller ET, Giordano T, Gu K, Shah V, Pei L, Zarbo RJ, et al. NF-kappaB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF. Nat Med 2007, 13:62-69. 10.1038/nm1519, 17159986.
-
(2007)
Nat Med
, vol.13
, pp. 62-69
-
-
Park, B.K.1
Zhang, H.2
Zeng, Q.3
Dai, J.4
Keller, E.T.5
Giordano, T.6
Gu, K.7
Shah, V.8
Pei, L.9
Zarbo, R.J.10
-
73
-
-
77950346282
-
Immunity, inflammation, and cancer
-
10.1016/j.cell.2010.01.025, 20303878
-
Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell 2010, 140:883-899. 10.1016/j.cell.2010.01.025, 20303878.
-
(2010)
Cell
, vol.140
, pp. 883-899
-
-
Grivennikov, S.I.1
Greten, F.R.2
Karin, M.3
-
74
-
-
0347302952
-
Cytokines in cancer pathogenesis and cancer therapy
-
10.1038/nrc1252, 14708024
-
Dranoff G. Cytokines in cancer pathogenesis and cancer therapy. Nat Rev Cancer 2004, 4:11-22. 10.1038/nrc1252, 14708024.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 11-22
-
-
Dranoff, G.1
-
75
-
-
4043088499
-
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
10.1016/j.cell.2004.07.013, 15294155
-
Greten FR, Eckmann L, Greten TF, Park JM, Li ZW, Egan LJ, Kagnoff MF, Karin M. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 2004, 118:285-296. 10.1016/j.cell.2004.07.013, 15294155.
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
Park, J.M.4
Li, Z.W.5
Egan, L.J.6
Kagnoff, M.F.7
Karin, M.8
-
76
-
-
63649143900
-
Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis
-
10.1038/nature07713, 2785034, 19204730
-
Ishii M, Egen JG, Klauschen F, Meier-Schellersheim M, Saeki Y, Vacher J, Proia RL, Germain RN. Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis. Nature 2009, 458:524-528. 10.1038/nature07713, 2785034, 19204730.
-
(2009)
Nature
, vol.458
, pp. 524-528
-
-
Ishii, M.1
Egen, J.G.2
Klauschen, F.3
Meier-Schellersheim, M.4
Saeki, Y.5
Vacher, J.6
Proia, R.L.7
Germain, R.N.8
-
77
-
-
52449092057
-
Targeting SphK1 as a new strategy against cancer
-
10.2174/138945008785132402, 2674575, 18691013
-
Shida D, Takabe K, Kapitonov D, Milstien S, Spiegel S. Targeting SphK1 as a new strategy against cancer. Curr Drug Targets 2008, 9:662-673. 10.2174/138945008785132402, 2674575, 18691013.
-
(2008)
Curr Drug Targets
, vol.9
, pp. 662-673
-
-
Shida, D.1
Takabe, K.2
Kapitonov, D.3
Milstien, S.4
Spiegel, S.5
-
78
-
-
33644830810
-
Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages
-
10.1016/j.ccr.2006.02.023, 16530706
-
Visentin B, Vekich JA, Sibbald BJ, Cavalli AL, Moreno KM, Matteo RG, Garland WA, Lu Y, Yu S, Hall HS, et al. Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages. Cancer Cell 2006, 9:225-238. 10.1016/j.ccr.2006.02.023, 16530706.
-
(2006)
Cancer Cell
, vol.9
, pp. 225-238
-
-
Visentin, B.1
Vekich, J.A.2
Sibbald, B.J.3
Cavalli, A.L.4
Moreno, K.M.5
Matteo, R.G.6
Garland, W.A.7
Lu, Y.8
Yu, S.9
Hall, H.S.10
-
79
-
-
29244457577
-
Sphingosine kinase-1 as a chemotherapy sensor in prostate adenocarcinoma cell and mouse models
-
10.1158/0008-5472.CAN-05-2702, 16357178
-
Pchejetski D, Golzio M, Bonhoure E, Calvet C, Doumerc N, Garcia V, Mazerolles C, Rischmann P, Teissie J, Malavaud B, Cuvillier O. Sphingosine kinase-1 as a chemotherapy sensor in prostate adenocarcinoma cell and mouse models. Cancer Res 2005, 65:11667-11675. 10.1158/0008-5472.CAN-05-2702, 16357178.
-
(2005)
Cancer Res
, vol.65
, pp. 11667-11675
-
-
Pchejetski, D.1
Golzio, M.2
Bonhoure, E.3
Calvet, C.4
Doumerc, N.5
Garcia, V.6
Mazerolles, C.7
Rischmann, P.8
Teissie, J.9
Malavaud, B.10
Cuvillier, O.11
-
80
-
-
77952065237
-
Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy
-
10.1186/1471-2407-10-202, 2875220, 20465837
-
Sadikovic B, Thorner P, Chilton-Macneill S, Martin JW, Cervigne NK, Squire J, Zielenska M. Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy. BMC Cancer 10:202. 10.1186/1471-2407-10-202, 2875220, 20465837.
-
BMC Cancer
, vol.10
, pp. 202
-
-
Sadikovic, B.1
Thorner, P.2
Chilton-Macneill, S.3
Martin, J.W.4
Cervigne, N.K.5
Squire, J.6
Zielenska, M.7
-
81
-
-
70350398634
-
Growth/differentiation factor-15 inhibits differentiation into osteoclasts--a novel factor involved in control of osteoclast differentiation
-
10.1016/j.diff.2009.07.008, 19695766
-
Vanhara P, Lincova E, Kozubik A, Jurdic P, Soucek K, Smarda J. Growth/differentiation factor-15 inhibits differentiation into osteoclasts--a novel factor involved in control of osteoclast differentiation. Differentiation 2009, 78:213-222. 10.1016/j.diff.2009.07.008, 19695766.
-
(2009)
Differentiation
, vol.78
, pp. 213-222
-
-
Vanhara, P.1
Lincova, E.2
Kozubik, A.3
Jurdic, P.4
Soucek, K.5
Smarda, J.6
-
82
-
-
33846034921
-
Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone
-
10.1007/s10555-006-9032-0, 17165130
-
Pratap J, Lian JB, Javed A, Barnes GL, van Wijnen AJ, Stein JL, Stein GS. Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone. Cancer Metastasis Rev 2006, 25:589-600. 10.1007/s10555-006-9032-0, 17165130.
-
(2006)
Cancer Metastasis Rev
, vol.25
, pp. 589-600
-
-
Pratap, J.1
Lian, J.B.2
Javed, A.3
Barnes, G.L.4
van Wijnen, A.J.5
Stein, J.L.6
Stein, G.S.7
-
83
-
-
66149160499
-
The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblasts
-
10.1002/jcb.22108, 2918404, 19259985
-
Teplyuk NM, Haupt LM, Ling L, Dombrowski C, Mun FK, Nathan SS, Lian JB, Stein JL, Stein GS, Cool SM, van Wijnen AJ. The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblasts. J Cell Biochem 2009, 107:144-154. 10.1002/jcb.22108, 2918404, 19259985.
-
(2009)
J Cell Biochem
, vol.107
, pp. 144-154
-
-
Teplyuk, N.M.1
Haupt, L.M.2
Ling, L.3
Dombrowski, C.4
Mun, F.K.5
Nathan, S.S.6
Lian, J.B.7
Stein, J.L.8
Stein, G.S.9
Cool, S.M.10
van Wijnen, A.J.11
-
84
-
-
27744551614
-
Syndecan-2
-
10.1016/j.biocel.2005.08.012, 16198615
-
Essner JJ, Chen E, Ekker SC. Syndecan-2. Int J Biochem Cell Biol 2006, 38:152-156. 10.1016/j.biocel.2005.08.012, 16198615.
-
(2006)
Int J Biochem Cell Biol
, vol.38
, pp. 152-156
-
-
Essner, J.J.1
Chen, E.2
Ekker, S.C.3
-
85
-
-
0037119429
-
Syndecan-2 mediates adhesion and proliferation of colon carcinoma cells
-
10.1074/jbc.M202435200, 12055189
-
Park H, Kim Y, Lim Y, Han I, Oh ES. Syndecan-2 mediates adhesion and proliferation of colon carcinoma cells. J Biol Chem 2002, 277:29730-29736. 10.1074/jbc.M202435200, 12055189.
-
(2002)
J Biol Chem
, vol.277
, pp. 29730-29736
-
-
Park, H.1
Kim, Y.2
Lim, Y.3
Han, I.4
Oh, E.S.5
-
86
-
-
0034095211
-
Ezrin links syndecan-2 to the cytoskeleton
-
Granes F, Urena JM, Rocamora N, Vilaro S. Ezrin links syndecan-2 to the cytoskeleton. J Cell Sci 2000, 113(Pt 7):1267-1276.
-
(2000)
J Cell Sci
, vol.113
, Issue.PART 7
, pp. 1267-1276
-
-
Granes, F.1
Urena, J.M.2
Rocamora, N.3
Vilaro, S.4
-
87
-
-
0029085123
-
Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate
-
10.1038/nm0995-944, 7585222
-
Nelson JB, Hedican SP, George DJ, Reddi AH, Piantadosi S, Eisenberger MA, Simons JW. Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate. Nat Med 1995, 1:944-949. 10.1038/nm0995-944, 7585222.
-
(1995)
Nat Med
, vol.1
, pp. 944-949
-
-
Nelson, J.B.1
Hedican, S.P.2
George, D.J.3
Reddi, A.H.4
Piantadosi, S.5
Eisenberger, M.A.6
Simons, J.W.7
-
88
-
-
10744225879
-
Vascular endothelial growth factor contributes to the prostate cancer-induced osteoblast differentiation mediated by bone morphogenetic protein
-
10.1158/0008-5472.CAN-03-1382, 14871830
-
Dai J, Kitagawa Y, Zhang J, Yao Z, Mizokami A, Cheng S, Nor J, McCauley LK, Taichman RS, Keller ET. Vascular endothelial growth factor contributes to the prostate cancer-induced osteoblast differentiation mediated by bone morphogenetic protein. Cancer Res 2004, 64:994-999. 10.1158/0008-5472.CAN-03-1382, 14871830.
-
(2004)
Cancer Res
, vol.64
, pp. 994-999
-
-
Dai, J.1
Kitagawa, Y.2
Zhang, J.3
Yao, Z.4
Mizokami, A.5
Cheng, S.6
Nor, J.7
McCauley, L.K.8
Taichman, R.S.9
Keller, E.T.10
-
89
-
-
0037162547
-
Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover
-
10.1073/pnas.152324099, 124965, 12118119
-
Street J, Bao M, deGuzman L, Bunting S, Peale FV, Ferrara N, Steinmetz H, Hoeffel J, Cleland JL, Daugherty A, et al. Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover. Proc Natl Acad Sci USA 2002, 99:9656-9661. 10.1073/pnas.152324099, 124965, 12118119.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 9656-9661
-
-
Street, J.1
Bao, M.2
deGuzman, L.3
Bunting, S.4
Peale, F.V.5
Ferrara, N.6
Steinmetz, H.7
Hoeffel, J.8
Cleland, J.L.9
Daugherty, A.10
-
90
-
-
0035313488
-
FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibition
-
10.1016/S0165-6147(00)01676-X, 11282421
-
Cross MJ, Claesson-Welsh L. FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibition. Trends Pharmacol Sci 2001, 22:201-207. 10.1016/S0165-6147(00)01676-X, 11282421.
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 201-207
-
-
Cross, M.J.1
Claesson-Welsh, L.2
-
91
-
-
0037699954
-
The biology of VEGF and its receptors
-
10.1038/nm0603-669, 12778165
-
Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med 2003, 9:669-676. 10.1038/nm0603-669, 12778165.
-
(2003)
Nat Med
, vol.9
, pp. 669-676
-
-
Ferrara, N.1
Gerber, H.P.2
LeCouter, J.3
-
92
-
-
4143133127
-
The Ras-related protein AGS1/RASD1 suppresses cell growth
-
10.1038/sj.onc.1207774, 15184869
-
Vaidyanathan G, Cismowski MJ, Wang G, Vincent TS, Brown KD, Lanier SM. The Ras-related protein AGS1/RASD1 suppresses cell growth. Oncogene 2004, 23:5858-5863. 10.1038/sj.onc.1207774, 15184869.
-
(2004)
Oncogene
, vol.23
, pp. 5858-5863
-
-
Vaidyanathan, G.1
Cismowski, M.J.2
Wang, G.3
Vincent, T.S.4
Brown, K.D.5
Lanier, S.M.6
-
93
-
-
36849057121
-
Mitogen-activated protein kinase phosphatase 1/dual specificity phosphatase 1 mediates glucocorticoid inhibition of osteoblast proliferation
-
10.1210/me.2007-0153, 2838148, 17761948
-
Horsch K, de Wet H, Schuurmans MM, Allie-Reid F, Cato AC, Cunningham J, Burrin JM, Hough FS, Hulley PA. Mitogen-activated protein kinase phosphatase 1/dual specificity phosphatase 1 mediates glucocorticoid inhibition of osteoblast proliferation. Mol Endocrinol 2007, 21:2929-2940. 10.1210/me.2007-0153, 2838148, 17761948.
-
(2007)
Mol Endocrinol
, vol.21
, pp. 2929-2940
-
-
Horsch, K.1
de Wet, H.2
Schuurmans, M.M.3
Allie-Reid, F.4
Cato, A.C.5
Cunningham, J.6
Burrin, J.M.7
Hough, F.S.8
Hulley, P.A.9
-
94
-
-
0032771030
-
A new human prostate carcinoma cell line, 22Rv1
-
10.1007/s11626-999-0115-4, 10462204
-
Sramkoski RM, Pretlow TG, Giaconia JM, Pretlow TP, Schwartz S, Sy MS, Marengo SR, Rhim JS, Zhang D, Jacobberger JW. A new human prostate carcinoma cell line, 22Rv1. In Vitro Cell Dev Biol Anim 1999, 35:403-409. 10.1007/s11626-999-0115-4, 10462204.
-
(1999)
In Vitro Cell Dev Biol Anim
, vol.35
, pp. 403-409
-
-
Sramkoski, R.M.1
Pretlow, T.G.2
Giaconia, J.M.3
Pretlow, T.P.4
Schwartz, S.5
Sy, M.S.6
Marengo, S.R.7
Rhim, J.S.8
Zhang, D.9
Jacobberger, J.W.10
-
95
-
-
33750822719
-
Detection of novel skeletogenesis target genes by comprehensive analysis of a Runx2(-/-) mouse model
-
10.1016/j.modgep.2006.05.014, 16829211
-
Hecht J, Seitz V, Urban M, Wagner F, Robinson PN, Stiege A, Dieterich C, Kornak U, Wilkening U, Brieske N, et al. Detection of novel skeletogenesis target genes by comprehensive analysis of a Runx2(-/-) mouse model. Gene Expr Patterns 2007, 7:102-112. 10.1016/j.modgep.2006.05.014, 16829211.
-
(2007)
Gene Expr Patterns
, vol.7
, pp. 102-112
-
-
Hecht, J.1
Seitz, V.2
Urban, M.3
Wagner, F.4
Robinson, P.N.5
Stiege, A.6
Dieterich, C.7
Kornak, U.8
Wilkening, U.9
Brieske, N.10
-
96
-
-
33847634759
-
Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2
-
10.1073/pnas.0611419104, 1805558, 17360627
-
Young DW, Hassan MQ, Yang XQ, Galindo M, Javed A, Zaidi SK, Furcinitti P, Lapointe D, Montecino M, Lian JB, et al. Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2. Proc Natl Acad Sci USA 2007, 104:3189-3194. 10.1073/pnas.0611419104, 1805558, 17360627.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 3189-3194
-
-
Young, D.W.1
Hassan, M.Q.2
Yang, X.Q.3
Galindo, M.4
Javed, A.5
Zaidi, S.K.6
Furcinitti, P.7
Lapointe, D.8
Montecino, M.9
Lian, J.B.10
-
97
-
-
53249121835
-
Gene array analysis reveals a common Runx transcriptional programme controlling cell adhesion and survival
-
10.1038/onc.2008.195, 2562521, 18560354
-
Wotton S, Terry A, Kilbey A, Jenkins A, Herzyk P, Cameron E, Neil JC. Gene array analysis reveals a common Runx transcriptional programme controlling cell adhesion and survival. Oncogene 2008, 27:5856-5866. 10.1038/onc.2008.195, 2562521, 18560354.
-
(2008)
Oncogene
, vol.27
, pp. 5856-5866
-
-
Wotton, S.1
Terry, A.2
Kilbey, A.3
Jenkins, A.4
Herzyk, P.5
Cameron, E.6
Neil, J.C.7
-
98
-
-
27144434594
-
A role for Runx2 in normal mammary gland and breast cancer bone metastasis
-
10.1002/jcb.20557, 16052475
-
Shore P. A role for Runx2 in normal mammary gland and breast cancer bone metastasis. J Cell Biochem 2005, 96:484-489. 10.1002/jcb.20557, 16052475.
-
(2005)
J Cell Biochem
, vol.96
, pp. 484-489
-
-
Shore, P.1
-
99
-
-
57349101476
-
Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancer
-
10.1210/en.2008-0680, 2613062, 18755791
-
Khalid O, Baniwal SK, Purcell DJ, Leclerc N, Gabet Y, Stallcup MR, Coetzee GA, Frenkel B. Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancer. Endocrinology 2008, 149:5984-5995. 10.1210/en.2008-0680, 2613062, 18755791.
-
(2008)
Endocrinology
, vol.149
, pp. 5984-5995
-
-
Khalid, O.1
Baniwal, S.K.2
Purcell, D.J.3
Leclerc, N.4
Gabet, Y.5
Stallcup, M.R.6
Coetzee, G.A.7
Frenkel, B.8
-
100
-
-
13444306168
-
Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo
-
10.1073/pnas.0409121102, 547873, 15665096
-
Javed A, Barnes GL, Pratap J, Antkowiak T, Gerstenfeld LC, van Wijnen AJ, Stein JL, Lian JB, Stein GS. Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo. Proc Natl Acad Sci USA 2005, 102:1454-1459. 10.1073/pnas.0409121102, 547873, 15665096.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1454-1459
-
-
Javed, A.1
Barnes, G.L.2
Pratap, J.3
Antkowiak, T.4
Gerstenfeld, L.C.5
van Wijnen, A.J.6
Stein, J.L.7
Lian, J.B.8
Stein, G.S.9
-
101
-
-
67749095787
-
Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNA
-
10.1210/me.2008-0470, 2718746, 19389811
-
Baniwal SK, Khalid O, Sir D, Buchanan G, Coetzee GA, Frenkel B. Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNA. Mol Endocrinol 2009, 23:1203-1214. 10.1210/me.2008-0470, 2718746, 19389811.
-
(2009)
Mol Endocrinol
, vol.23
, pp. 1203-1214
-
-
Baniwal, S.K.1
Khalid, O.2
Sir, D.3
Buchanan, G.4
Coetzee, G.A.5
Frenkel, B.6
-
102
-
-
34447264104
-
The role of tumor microenvironment in prostate cancer bone metastasis
-
10.1002/jcb.21214, 17387734
-
Morrissey C, Vessella RL. The role of tumor microenvironment in prostate cancer bone metastasis. J Cell Biochem 2007, 101:873-886. 10.1002/jcb.21214, 17387734.
-
(2007)
J Cell Biochem
, vol.101
, pp. 873-886
-
-
Morrissey, C.1
Vessella, R.L.2
-
103
-
-
4644261592
-
Mechanisms of bone metastasis
-
10.1056/NEJMra030831, 15084698
-
Roodman GD. Mechanisms of bone metastasis. N Engl J Med 2004, 350:1655-1664. 10.1056/NEJMra030831, 15084698.
-
(2004)
N Engl J Med
, vol.350
, pp. 1655-1664
-
-
Roodman, G.D.1
-
104
-
-
0036675220
-
Metastasis to bone: causes, consequences and therapeutic opportunities
-
10.1038/nrc867, 12154351
-
Mundy GR. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer 2002, 2:584-593. 10.1038/nrc867, 12154351.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 584-593
-
-
Mundy, G.R.1
-
105
-
-
11144237716
-
Osteoblasts in prostate cancer metastasis to bone
-
10.1038/nrc1528, 15630412
-
Logothetis CJ, Lin SH. Osteoblasts in prostate cancer metastasis to bone. Nat Rev Cancer 2005, 5:21-28. 10.1038/nrc1528, 15630412.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 21-28
-
-
Logothetis, C.J.1
Lin, S.H.2
-
106
-
-
50349092984
-
Retroviral-mediated gene therapy for the differentiation of primary cells into a mineralizing osteoblastic phenotype
-
full_text, 18679633
-
Phillips JE, Garcia AJ. Retroviral-mediated gene therapy for the differentiation of primary cells into a mineralizing osteoblastic phenotype. Methods Mol Biol 2008, 433:333-354. full_text, 18679633.
-
(2008)
Methods Mol Biol
, vol.433
, pp. 333-354
-
-
Phillips, J.E.1
Garcia, A.J.2
-
107
-
-
49349115664
-
CCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexes
-
10.1016/j.molcel.2008.08.001, 2562329, 18722177
-
Kim JH, Yang CK, Heo K, Roeder RG, An W, Stallcup MR. CCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexes. Mol Cell 2008, 31:510-519. 10.1016/j.molcel.2008.08.001, 2562329, 18722177.
-
(2008)
Mol Cell
, vol.31
, pp. 510-519
-
-
Kim, J.H.1
Yang, C.K.2
Heo, K.3
Roeder, R.G.4
An, W.5
Stallcup, M.R.6
-
108
-
-
0001677717
-
Controlling the false discovery rate: a practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. Journal of the Royal Statistical Society Series B 1995, 57:289-300.
-
(1995)
Journal of the Royal Statistical Society Series B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
109
-
-
0038069626
-
Assessment of Gelatinases (MMP-2 and MMP-9 by Gelatin Zymography
-
Toth M, Fridman R. Assessment of Gelatinases (MMP-2 and MMP-9 by Gelatin Zymography. Metastasis Research Protocols 2008, 57:163-174.
-
(2008)
Metastasis Research Protocols
, vol.57
, pp. 163-174
-
-
Toth, M.1
Fridman, R.2
-
110
-
-
0036595629
-
Epithelial-mesenchymal transitions in tumour progression
-
10.1038/nrc822, 12189386
-
Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2002, 2:442-454. 10.1038/nrc822, 12189386.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
-
111
-
-
33748171960
-
The c-Myc target gene network
-
10.1016/j.semcancer.2006.07.014, 16904903
-
Dang CV, O'Donnell KA, Zeller KI, Nguyen T, Osthus RC, Li F. The c-Myc target gene network. Semin Cancer Biol 2006, 16:253-264. 10.1016/j.semcancer.2006.07.014, 16904903.
-
(2006)
Semin Cancer Biol
, vol.16
, pp. 253-264
-
-
Dang, C.V.1
O'Donnell, K.A.2
Zeller, K.I.3
Nguyen, T.4
Osthus, R.C.5
Li, F.6
-
112
-
-
33745737494
-
Myc-binding-site recognition in the human genome is determined by chromatin context
-
10.1038/ncb1434, 16767079
-
Guccione E, Martinato F, Finocchiaro G, Luzi L, Tizzoni L, Dall'Olio V, Zardo G, Nervi C, Bernard L, Amati B. Myc-binding-site recognition in the human genome is determined by chromatin context. Nat Cell Biol 2006, 8:764-770. 10.1038/ncb1434, 16767079.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 764-770
-
-
Guccione, E.1
Martinato, F.2
Finocchiaro, G.3
Luzi, L.4
Tizzoni, L.5
Dall'Olio, V.6
Zardo, G.7
Nervi, C.8
Bernard, L.9
Amati, B.10
-
113
-
-
33748474838
-
A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development
-
10.1084/jem.20052144, 2118398, 16940167
-
Burns JM, Summers BC, Wang Y, Melikian A, Berahovich R, Miao Z, Penfold ME, Sunshine MJ, Littman DR, Kuo CJ, et al. A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. J Exp Med 2006, 203:2201-2213. 10.1084/jem.20052144, 2118398, 16940167.
-
(2006)
J Exp Med
, vol.203
, pp. 2201-2213
-
-
Burns, J.M.1
Summers, B.C.2
Wang, Y.3
Melikian, A.4
Berahovich, R.5
Miao, Z.6
Penfold, M.E.7
Sunshine, M.J.8
Littman, D.R.9
Kuo, C.J.10
-
114
-
-
73449122689
-
VEGF autoregulates its proliferative and migratory ERK1/2 and p38 cascades by enhancing the expression of DUSP1 and DUSP5 phosphatases in endothelial cells
-
10.1152/ajpcell.00058.2009, 19741200
-
Bellou S, Hink MA, Bagli E, Panopoulou E, Bastiaens PI, Murphy C, Fotsis T. VEGF autoregulates its proliferative and migratory ERK1/2 and p38 cascades by enhancing the expression of DUSP1 and DUSP5 phosphatases in endothelial cells. Am J Physiol Cell Physiol 2009, 297:C1477-1489. 10.1152/ajpcell.00058.2009, 19741200.
-
(2009)
Am J Physiol Cell Physiol
, vol.297
-
-
Bellou, S.1
Hink, M.A.2
Bagli, E.3
Panopoulou, E.4
Bastiaens, P.I.5
Murphy, C.6
Fotsis, T.7
-
115
-
-
0034974903
-
Differential regulation of sphingosine-1-phosphate- and VEGF-induced endothelial cell chemotaxis. Involvement of G(ialpha2)-linked Rho kinase activity
-
Liu F, Verin AD, Wang P, Day R, Wersto RP, Chrest FJ, English DK, Garcia JG. Differential regulation of sphingosine-1-phosphate- and VEGF-induced endothelial cell chemotaxis. Involvement of G(ialpha2)-linked Rho kinase activity. Am J Respir Cell Mol Biol 2001, 24:711-719.
-
(2001)
Am J Respir Cell Mol Biol
, vol.24
, pp. 711-719
-
-
Liu, F.1
Verin, A.D.2
Wang, P.3
Day, R.4
Wersto, R.P.5
Chrest, F.J.6
English, D.K.7
Garcia, J.G.8
-
116
-
-
0033783522
-
Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation
-
10.1172/JCI10905, 314347, 11032855
-
Liu Y, Wada R, Yamashita T, Mi Y, Deng CX, Hobson JP, Rosenfeldt HM, Nava VE, Chae SS, Lee MJ, et al. Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. J Clin Invest 2000, 106:951-961. 10.1172/JCI10905, 314347, 11032855.
-
(2000)
J Clin Invest
, vol.106
, pp. 951-961
-
-
Liu, Y.1
Wada, R.2
Yamashita, T.3
Mi, Y.4
Deng, C.X.5
Hobson, J.P.6
Rosenfeldt, H.M.7
Nava, V.E.8
Chae, S.S.9
Lee, M.J.10
-
117
-
-
32944469631
-
Espin gene (ESPN) mutations associated with autosomal dominant hearing loss cause defects in microvillar elongation or organisation
-
10.1136/jmg.2005.032086, 2564636, 15930085
-
Donaudy F, Zheng L, Ficarella R, Ballana E, Carella M, Melchionda S, Estivill X, Bartles JR, Gasparini P. Espin gene (ESPN) mutations associated with autosomal dominant hearing loss cause defects in microvillar elongation or organisation. J Med Genet 2006, 43:157-161. 10.1136/jmg.2005.032086, 2564636, 15930085.
-
(2006)
J Med Genet
, vol.43
, pp. 157-161
-
-
Donaudy, F.1
Zheng, L.2
Ficarella, R.3
Ballana, E.4
Carella, M.5
Melchionda, S.6
Estivill, X.7
Bartles, J.R.8
Gasparini, P.9
-
118
-
-
0029896454
-
Identification and characterization of espin, an actin-binding protein localized to the F-actin-rich junctional plaques of Sertoli cell ectoplasmic specializations
-
Bartles JR, Wierda A, Zheng L. Identification and characterization of espin, an actin-binding protein localized to the F-actin-rich junctional plaques of Sertoli cell ectoplasmic specializations. J Cell Sci 1996, 109(Pt 6):1229-1239.
-
(1996)
J Cell Sci
, vol.109
, Issue.PART 6
, pp. 1229-1239
-
-
Bartles, J.R.1
Wierda, A.2
Zheng, L.3
-
119
-
-
0038686623
-
Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development
-
10.1016/S1534-5807(03)00169-2, 12852851
-
Gu C, Rodriguez ER, Reimert DV, Shu T, Fritzsch B, Richards LJ, Kolodkin AL, Ginty DD. Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development. Dev Cell 2003, 5:45-57. 10.1016/S1534-5807(03)00169-2, 12852851.
-
(2003)
Dev Cell
, vol.5
, pp. 45-57
-
-
Gu, C.1
Rodriguez, E.R.2
Reimert, D.V.3
Shu, T.4
Fritzsch, B.5
Richards, L.J.6
Kolodkin, A.L.7
Ginty, D.D.8
-
120
-
-
34548214630
-
MUC1: a target molecule for cancer therapy
-
10.4161/cbt.6.4.4201, 18027437
-
Singh R, Bandyopadhyay D. MUC1: a target molecule for cancer therapy. Cancer Biol Ther 2007, 6:481-486. 10.4161/cbt.6.4.4201, 18027437.
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 481-486
-
-
Singh, R.1
Bandyopadhyay, D.2
-
121
-
-
0033912780
-
Evidence for expression of some microtubule-associated protein 1B in neurons as a plasma membrane glycoprotein
-
10.1046/j.1471-4159.2000.0750553.x, 10899930
-
Tanner SL, Franzen R, Jaffe H, Quarles RH. Evidence for expression of some microtubule-associated protein 1B in neurons as a plasma membrane glycoprotein. J Neurochem 2000, 75:553-562. 10.1046/j.1471-4159.2000.0750553.x, 10899930.
-
(2000)
J Neurochem
, vol.75
, pp. 553-562
-
-
Tanner, S.L.1
Franzen, R.2
Jaffe, H.3
Quarles, R.H.4
-
122
-
-
69549122682
-
Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation
-
10.1242/jcs.046680, 2909319, 19596797
-
Stylli SS, Stacey TT, Verhagen AM, Xu SS, Pass I, Courtneidge SA, Lock P. Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation. J Cell Sci 2009, 122:2727-2740. 10.1242/jcs.046680, 2909319, 19596797.
-
(2009)
J Cell Sci
, vol.122
, pp. 2727-2740
-
-
Stylli, S.S.1
Stacey, T.T.2
Verhagen, A.M.3
Xu, S.S.4
Pass, I.5
Courtneidge, S.A.6
Lock, P.7
-
123
-
-
0025858450
-
Expression of M-cadherin, a member of the cadherin multigene family, correlates with differentiation of skeletal muscle cells
-
10.1073/pnas.88.18.8024, 52438, 1840697
-
Donalies M, Cramer M, Ringwald M, Starzinski-Powitz A. Expression of M-cadherin, a member of the cadherin multigene family, correlates with differentiation of skeletal muscle cells. Proc Natl Acad Sci USA 1991, 88:8024-8028. 10.1073/pnas.88.18.8024, 52438, 1840697.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 8024-8028
-
-
Donalies, M.1
Cramer, M.2
Ringwald, M.3
Starzinski-Powitz, A.4
-
124
-
-
0032545407
-
Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage
-
10.1074/jbc.273.51.34406, 9852107
-
Hu SI, Carozza M, Klein M, Nantermet P, Luk D, Crowl RM. Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage. J Biol Chem 1998, 273:34406-34412. 10.1074/jbc.273.51.34406, 9852107.
-
(1998)
J Biol Chem
, vol.273
, pp. 34406-34412
-
-
Hu, S.I.1
Carozza, M.2
Klein, M.3
Nantermet, P.4
Luk, D.5
Crowl, R.M.6
|