Chapter 9. Thrombosis and Coagulation

Annual Reports in Medicinal Chemistry

Volumn 33, Issue C, 1998, Pages 81-90

  Vacca, Joseph P ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77956716245     PISSN: 00657743     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-7743(08)61074-X     Document Type: Chapter

References (52)

1. Shafer J., and Gould R. Drug Disc. Design 1 (1994) 419
2. Edmunds J., Rapundalo S., and Siddiqui M. Ann. Rep. Med. Chem. 31 (1996) 51
3. Ripka W.C., and Vlasuk G.P. Ann. Rep. Med. Chem. 32 (1997) 71
4. Ripka W.C. Curr. Opin. Chem. Biol. 1 (1997) 242
5. Wiley M.R., and Fisher M.J. Exp. Opin. Ther. Patents 7 (1997) 1265
6. Bajusz S., Barabas E., Tolnay P., Szell E., and Bagdy D. Int. J. Pept. Protein Res. 12 (1978) 217
7. Tamura S.Y., Semple J.E., Reiner J.E., Goldman E.A., Brunck T.K., Lim-Wilby M.S., Carpenter S.H., Rote W.E., Oldeshulte G.L., Richard B.M., Nutt R.F., and Ripka W.C. Bioorg. Med. Chem. Lett. 7 12 (1997) 1543
8. Lee S., Alexander R.S., Smallwood A., Trievel R., Mersinger L., Weber P.C., and Kettner C. Biochem. 36 43 (1997) 13180
9. von der Saal W., Kucznierz R., Leinert H., and Engh R.A. Bioorg. Med. Chem. Lett. 7 10 (1997) 1283
10. Watson, N.S., Pass, M. and Patel, V., WO922589-A1, June 26, 1997
11. Naylor-Olsen, A.M., Ponticello, G.S., Vacca, J.P., Hungate, R.W., Coburn, C.A., Phillips, B.T., Lewis, S.D. and Fraley, M.E., WO9810763, Sept. 9, 1997
12. Fraley, M.E., Hungate, R.W., Naylor-Olsen, A.M. & Vacca, J.P., WO9806396-A1, Feb. 19, 1998
13. Chirgadze N.Y., Sall D.J., Klimkowski V.J., Clawson D.K., Briggs S.L., Hermann R., Smith G.F., Gifford-Moore D.S., and Wery J.-P. Protein Sci. 6 (1997) 1412
14. Sall D.J., Bastian J.A., Briggs S.L., Buben J.A., Chirgadze N.Y., Clawson D.K., Denney M.L., Giera D.D., Gifford-Moore D.S., Harper R.W., Hauser K.L., Klimkowski V.J., Kohn T.J., Lin H., McCowan J.R., Palkowitz A.D., Smith G.F., Takeuchi K., Thrasher K.J., Tinsley J.M., Utterback B.G., Yan S.B., and Zhang M. J. Med. Chem. 40 22 (1997) 3489
15. Schwarz R.P., Becker J.C.P., Brooks R.L., Hursting M.J., Joffrion J.L., Knappenberger G.D., Kogan T.P., Kogan P.W., and McKinney A.A. Clin. Appl. Thromb. Haemostasis 3 1 (1997) 1
16. Kim S., Hwang S.Y., Kim Y.K., Yun M., and Oh Y.S. Bioorg. Med. Chem. Lett. 7 7 (1997) 769
17. Oh Y.S., Yun M., Huang S.Y., Hong S., Shin Y., Lee K., Yoon K.H., Yoo Y.J., Kim D.S., Lee S.H., Lee Y.H., Park H.D., Lee C.H., Lee S.K., and Kim S. Bioorg. Med. Chem. Lett. 8 7 (1998) 631
18. Sturzebecher J., Prasa D., Hauptmann J., Vieweg H., and Wikstrom P. J. Med. Chem. 40 (1997) 3091
19. Allen, M., Abel, S.M., Barber, C.G., Cussans, N.J., Danilewicz, J.C., Ellis, D., Hawkeswood, E., Herron, M., Holland, S., Fox, D.N.A., James, K., Kobylecki, R.J., Overington, J.P., Pandit, J., Parmer, H., Powling, M., Rance, D.J., Taylor, W. and Shepperson, N.B., 215th ACS Natl. Meet., Mar 29-Apr 2, 1998, Dallas TX, Abst MEDI200
20. Preville P., He J.X., Tarazi M., Siddiqui M.A., Cody W.L., and Doherty A.M. Bioorg. Med. Chem. Lett. 7 12 (1997) 1563
21. Tegre-Nilsson A.-C., Bylund R., Gustafsson D., Gyzander E., and Eriksson U. Thromb. Res. 2 (1997) 133
22. Gustafsson D., Antonsson T., Bylund R., Eriksson U., Gyzander E., Nilsson I., Elg M., Mattsson C., Deinum J., Pehrsson S., Karlsson O., Nilsson A., and Sorensen H. Thromb. Haemostasis 79 (1998) 110
23. Schacht, A.L., Smith, G.F. and Wiley, M.R., US Patent 5,705,487-A (1998)
24. Klimkowski, V., Schacht, A. and Wiley, M., WO9749404-A1, Dec. 31, 1997
25. Gustafsson, D. and Nystrom, J., WO970224-A1, Jan. 23, 1997
26. Tucker T.J., Lumma W.C., Mulichak A.M., Chen Z., Naylor-Olsen A.M., Lewis S.D., Lucas R., Freidinger R.M., and Kuo L.C. J. Med. Chem. 40 6 (1997) 830
27. Tucker T.J., Lumma W.C., Lewis S.D., Gardell S.J., Lucas B.J., Baskin E.P., Woltmann R., Lynch J.J., Lyle E.A., Appleby S.D., Chen I.-W., Dancheck K.B., and Vacca J.P. J. Med. Chem. 40 11 (1997) 1565
28. Tucker T.J., Lumma W.C., Lewis S.D., Gardell S.J., Lucas B.J., Sisko J.T., Lynch J.J., Lyle E.A., Baskin E.P., Woltmann R.F., Appleby S.D., Chen I.-W., Dancheck K.B., Naylor-Olsen A.M., Krueger J.A., Cooper C.M., and Vacca J.P. J. Med. Chem. 40 22 (1997) 3687
29. Brady S.F., Stauffer K.J., Lumma W.C., Smith G.M., Ramjit H.G., Lewis S.D., Lucas B.J., Gardell S.J., Lyle E.A., Appleby S.D., Cook J.J., Holahan M.A., Stranieri M.T., Lynch Jr. J.J., Lin J.H., Chen I.-W., Vastag K., Naylor-Olsen A.M., and Vacca J.P. J. Med. Chem. 41 3 (1998) 401
30. Feng D.-M., Gardell S.J., Lewis S.D., Bock M.G., Chen Z., Freidinger R.M., Naylor-Olsen A.M., Ramjit H.G., Woltmann R., Baskin E.P., Lynch J.J., Lucas R., Shafer J.A., Dancheck K.B., Chen I.-W., Mao S.-S., Krueger J.A., Hare T.R., Mulichak A.M., and Vacca J.P. J. Med. Chem. 40 23 (1997) 3726
31. Sanderson P.E.J., Dyer D.L., Naylor-Olsen A.M., Vacca J.P., Gardell S.J., Lewis S.D., Lucas Jr. B.J., Lyle E.A., Lynch Jr. J.J., and Mulichak A.M. Bioorg. Med. Chem. Lett. 7 12 (1997) 1497
32. Sanderson P.E.J., Cutrona K.J., Dorsey B.D., Dyer D.L., McDonough C.M., Naylor-Olsen A.M., Chen I.-W., Chen Z., Cook J.J., Gardell S.J., Krueger J.A., Lewis S.D., Lin J.H., Lucas Jr. B.J., Lyle E.A., Lynch Jr. J.J., Stranieri M.T., Vastag K., Shafer J.A., and Vacca J.P. Bioorg. Med. Chem. Lett. 8 (1998) 817
33. Sanderson, P.E.J., 215th ACS Natl. Mtg., Mar 29-Apr 2, 1998, Dallas TX, Abst MEDI 199
34. Lumma Jr. W.C., Witherup K.M., Tucker T.J., Brady S.F., Sisko J.T., Naylor-Olsen A.M., Lewis S.D., Lucas B.J., and Vacca J.P. J. Med. Chem. 41 7 (1998) 1011
35. Brandstetter H., Kuhne A., Bode W., Huber R., von der Saal W., Wirthensohn K., and Engh R.A. J. Biol. Chem. 271 (1996) 29988
36. Sato K., Kawasaki T., Taniuchi Y., Hirayama F., Koshio H., and Matsumoto Y. Eur. J. Pharm. 339 (1997) 141
37. Nomoto, T., Kawamoto, H., Sato, S., Honma, M., Miyaji, M. and Takaka, Y., JP10001467, Jan. 6, (1998)
38. Nomoto, T., Hayashi, K., Kawamoto, H., Sato, S., Miyaji, M. and Koka, Y., JP10017549, Jan. 20, (1998)
39. Dominguez, C., Han, Q., Duffy, D.E., Park, J.M., Quan, M.L., Rossi, K.A. and Wexler, R.R., WO9801428-A1, Jan. 15, 1998
40. Sturzebecher J., Sturzebecher U., Viewig H., Wagner G., Hauptmann J., and Markwardt F. Thromb. Res. 54 (1989) 245
41. Shaw, K.J., Arnaiz, D.O., Buckman, B.O., Chou, Y.L., Davey, D.D., Eagen, K., Griedel, B.D., Guilford, W.J., Kochanny, M., Mohan, R., Ng, H., Phillips, G.B., Pinkerton, M., Sakata, S., Wu, S.C., Xu, W., Yun, W., Zhao, Z., Light, D., Dallas, J., Koovakkat, S., Whitlow, M., Liang, A., Trinh, L., Ho, E., Smith, D., Subramanyam, B., Vergona, R., Walters, J., White, K.A., Sullivan, M.E. and Morrissey, M.M., 215th ACS Natl. Mtg., Mar 29-Apr 2, 1998, Dallas TX, Abst MEDI201
42. White H.D. Thromb. Haemostasis 78 1 (1997) 364
43. Verstraete M. Thromb. Haemostasis 78 1 (1997) 357
44. Hermann J.P.R., Kutryk M.J.B., and Serruys P.W. Thromb. Haemostasis 78 1 (1997) 367
45. Catella-Lawson F. Coronary Artery Disease 8 2 (1997) 105
46. Ewenstein B.M. N. Engl. J. Med. 337 19 (1997) 1383
47. Eriksson B.I., Wille-Jorgensen P., Kalebo P., Mouret P., Rosencher N., Bosch P., Baur M., Ekman S., Bach D., Lindbratt S., and Close P. N. Engl. J. Med. 337 19 (1997) 1329
48. Cohen M., Demers C., Gurfinkel E.P., Turpie A.G.G., Fromell G.J., Goodman S., Langer A., Califf R.M., Fox K.A.A., Premmereur Ch.B.J., and Bigonzi F. N. Engl. J. Med. 337 7 (1997) 447
49. The Columbus Investigators, N. Engl. J. Med., 337, (10), 657, (1997)
50. Schwartz Jr. R.P., Becker J.C.P., Brooks R.L., Hursting M.J., Joffrion J.L., Knappenberger G.D., Kogan T.P., Kogan P.W., and McKinney A.A. Clin. Appl. Thromb. Haemostasis 3 1 (1997) 1
51. TRIM Study Group. Eur. Heart J. 18 (1997) 1416
52. Bounameaux H., Ehringer H., Hulting J., Rasche H., Rapold H.J., Zultak M., Rames A., Basle C.H., ten Cate J.W., Schneider P.A., Geneva C.H., Schmitt H.E., Slosman D.O., Perrier A., Spannagl H., Gschwandtner M.E., Banyai M., Koppensteiner R., Minar E., Stumpfler A., Haumer M., Verhaeghe R., Vermylen J., Wautrecht J.C., Taghizadeh K., Bruhn H.D., Lins M., Zurborn K.H., Schwarzenberg H., Schauer J., Scheel H., Ruhlmann C., Voigt H., Wagner T., Siemens H.J., Schwieder G., Heene D., Dempfle C.E., Harenberg J., Pfitzner S., Brockhaus W., Schuster O., Weisshaar K., Sebiger R., Hofmann B., Anders O., Krammer B., Plath F., Lestin H., Baumann N., Ehrertreich U., MullerEsch G., Ruprecht B., Wedeen G., Larfars G., Wallvik J., Bjuhr O., Didier D., Desmarais S., Wutschert R., deMoerloose P., Christen Y., Bernard C., Kupka S., Kirisits A., Janssen M., Verweij G., Kraaj C.J., Sittner W.D., Hanka U., Maier A., Johansson A.S., Johansson E., Olesen M., Breier E., Wittke B., Goggin T., Stephenson C., Turkish M., Williams L., Dutreix C., Gautsch A., Nonn D., Ward R., Lowe P., Lad K., Green D., and Gravel A.I. Thromb. Haemostasis 78 (1997) 997