-
1
-
-
0029915374
-
Prevention of deep-vein thrombosis after total hip replacement: Direct thrombin inhibition with recombinant hirudin, CGP 39393
-
Eriksson BI, Ekman S, Kälebo P, Zachrisson B, Bach D, Close P. Prevention of deep-vein thrombosis after total hip replacement: Direct thrombin inhibition with recombinant hirudin, CGP 39393. Lancet 1996; 347: 635-9.
-
(1996)
Lancet
, vol.347
, pp. 635-639
-
-
Eriksson, B.I.1
Ekman, S.2
Kälebo, P.3
Zachrisson, B.4
Bach, D.5
Close, P.6
-
2
-
-
0029835392
-
A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes
-
The global use of strategies to open occluded coronary arteries (GUSTO) IIb investigators. A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes. N Engl J Med 1996; 335: 775-82.
-
(1996)
N Engl J Med
, vol.335
, pp. 775-782
-
-
-
3
-
-
0029788104
-
Hirudin in acute myocardial infarction. Thrombolysis and thrombin Inhibition in myocardial infarction (TIMI) 9B trial
-
Antman EM. Hirudin in acute myocardial infarction. Thrombolysis and thrombin Inhibition in myocardial infarction (TIMI) 9B trial. Circulation 1996; 94: 911-21.
-
(1996)
Circulation
, vol.94
, pp. 911-921
-
-
Antman, E.M.1
-
4
-
-
0026347092
-
Argatroban, a selective, potent thrombin inhibitor
-
Bush LR. Argatroban, a selective, potent thrombin inhibitor. Cardiovasc Drug Rev 1991; 9: 247-63.
-
(1991)
Cardiovasc Drug Rev
, vol.9
, pp. 247-263
-
-
Bush, L.R.1
-
5
-
-
0029147936
-
Challenges in the development of orally bioavailable thrombin active site inhibitors
-
Kimball SD. Challenges in the development of orally bioavailable thrombin active site inhibitors. Blood Coagul Fibrinol 1995; 6: 511-9.
-
(1995)
Blood Coagul Fibrinol
, vol.6
, pp. 511-519
-
-
Kimball, S.D.1
-
8
-
-
0025094310
-
The selective inhibition of thrombin by peptides of boroarginine
-
Kettner C, Mersinger L, Knabb R. The selective inhibition of thrombin by peptides of boroarginine. J Biol Chem 1990; 265: 18289-97.
-
(1990)
J Biol Chem
, vol.265
, pp. 18289-18297
-
-
Kettner, C.1
Mersinger, L.2
Knabb, R.3
-
9
-
-
0023487426
-
Clinical pharmacology of tranexamic acid
-
Åstedt B. Clinical pharmacology of tranexamic acid. Scand J Gastroentol Suppl 1987; 137: 22-5.
-
(1987)
Scand J Gastroentol Suppl
, vol.137
, pp. 22-25
-
-
Åstedt, B.1
-
10
-
-
0017095326
-
Occurrence of C1 inactivator and other proteinase inhibitors in euglobulin fractions and their influence on fibrinolytic activity
-
Kluft C. Occurrence of C1 inactivator and other proteinase inhibitors in euglobulin fractions and their influence on fibrinolytic activity. Haemost 1976; 5: 136-46.
-
(1976)
Haemost
, vol.5
, pp. 136-146
-
-
Kluft, C.1
-
11
-
-
0022462370
-
Effect of a selective thrombin inhibitor MCI-9038 on fibrinolysis in vitro and in vivo
-
Tamao Y, Yamamoto T, Kikumoto R, Hara H, Itoh J, Hirata T, Mineo K, Okamoto S. Effect of a selective thrombin inhibitor MCI-9038 on fibrinolysis in vitro and in vivo. Thromb Haemost 1986; 56: 28-34.
-
(1986)
Thromb Haemost
, vol.56
, pp. 28-34
-
-
Tamao, Y.1
Yamamoto, T.2
Kikumoto, R.3
Hara, H.4
Itoh, J.5
Hirata, T.6
Mineo, K.7
Okamoto, S.8
-
12
-
-
0029831492
-
New model for in vivo studies of pharmacological interventions with endogenous fibrinolysis: Effects of thrombin inhibitors
-
Lenfors S, Gustafsson D. New model for in vivo studies of pharmacological interventions with endogenous fibrinolysis: Effects of thrombin inhibitors. Semin Thromb Haemost 1996; 22: 335-42.
-
(1996)
Semin Thromb Haemost
, vol.22
, pp. 335-342
-
-
Lenfors, S.1
Gustafsson, D.2
-
13
-
-
2642666477
-
The mechanism of binding of low-molecular-weight active site inhibitors to human α-thrombin
-
accepted
-
Nilsson T, Sjöling-Ericksson Å, Deinum J. The mechanism of binding of low-molecular-weight active site inhibitors to human α-thrombin. J Enzym Inhib 1997; accepted.
-
(1997)
J Enzym Inhib
-
-
Nilsson, T.1
Sjöling-Ericksson, Å.2
Deinum, J.3
-
14
-
-
0025328906
-
Highly active and selective anticoagulants: D-Phe-Pro-Arg-H, a free tripeptide aldehyde prone to spontaneous inactivation, and its stable N-methyl derivative, D-MePhe-Pro-Arg-H
-
Bajusz S, Szell E, Bagdy D, Barabas E, Horvath G, Dioszegi M, Fittler Z, Szabo G, Juhasz A, Tomori E, Szilagyi G. Highly active and selective anticoagulants: D-Phe-Pro-Arg-H, a free tripeptide aldehyde prone to spontaneous inactivation, and its stable N-methyl derivative, D-MePhe-Pro-Arg-H. J Medicinal Chem 1990; 33: 1729-35.
-
(1990)
J Medicinal Chem
, vol.33
, pp. 1729-1735
-
-
Bajusz, S.1
Szell, E.2
Bagdy, D.3
Barabas, E.4
Horvath, G.5
Dioszegi, M.6
Fittler, Z.7
Szabo, G.8
Juhasz, A.9
Tomori, E.10
Szilagyi, G.11
-
15
-
-
0029778319
-
Orally effective CVS-1123 prevents coronary artery thrombosis in the conscious dog
-
Cousins GR, Friedrichs GS, Sudo Y, Rebello SS, Rote WE, Vlasuk GP, Nolan TG, Mendoza C, Lucchesi BR. Orally effective CVS-1123 prevents coronary artery thrombosis in the conscious dog. Circulation 1996; 94: 1705-12.
-
(1996)
Circulation
, vol.94
, pp. 1705-1712
-
-
Cousins, G.R.1
Friedrichs, G.S.2
Sudo, Y.3
Rebello, S.S.4
Rote, W.E.5
Vlasuk, G.P.6
Nolan, T.G.7
Mendoza, C.8
Lucchesi, B.R.9
-
16
-
-
0030707669
-
The importance of enzyme inhibition kinetics for thrombin inhibitors in a rat model of arterial thrombosis
-
EIg M, Gustafsson D, Deinum J. The importance of enzyme inhibition kinetics for thrombin inhibitors in a rat model of arterial thrombosis. Thromb Haemost 1997; 78: 1286-92.
-
(1997)
Thromb Haemost
, vol.78
, pp. 1286-1292
-
-
Eig, M.1
Gustafsson, D.2
Deinum, J.3
-
18
-
-
0030932442
-
In vitro effects of inogatran, a selective LMW thrombin Inhibitor
-
Teger-Nilsson AC, Bylund R, Gustafsson D, Gyzander E, Eriksson U. In vitro effects of inogatran, a selective LMW thrombin Inhibitor. Thromb Res 1997; 85:133-45.
-
(1997)
Thromb Res
, vol.85
, pp. 133-145
-
-
Teger-Nilsson, A.C.1
Bylund, R.2
Gustafsson, D.3
Gyzander, E.4
Eriksson, U.5
-
19
-
-
0029037404
-
Recombinant hirudin (HBW 023): Biological data often patients with severe venous thromboembolism
-
Bridey F, Dreyfus M, Parent F, Bros A, Fischer AM, Camez A, Simonneau G, Duroux P, Meyer D. Recombinant hirudin (HBW 023): Biological data often patients with severe venous thromboembolism. Am J Hematol 1995; 49: 67-72.
-
(1995)
Am J Hematol
, vol.49
, pp. 67-72
-
-
Bridey, F.1
Dreyfus, M.2
Parent, F.3
Bros, A.4
Fischer, A.M.5
Camez, A.6
Simonneau, G.7
Duroux, P.8
Meyer, D.9
-
20
-
-
0026763390
-
Pharmacologic aspects of the development of selective synthetic thrombin inhibitors as anticoagulants
-
Hauptmann J, Markwardt F. Pharmacologic aspects of the development of selective synthetic thrombin inhibitors as anticoagulants. Semin Thromb Hemost 1992; 18: 200-17.
-
(1992)
Semin Thromb Hemost
, vol.18
, pp. 200-217
-
-
Hauptmann, J.1
Markwardt, F.2
-
21
-
-
0026563721
-
A strategy for a rational approach to designing synthetic selective inhibitors
-
Hijikata-Okunomiya A, Okamoto S. A strategy for a rational approach to designing synthetic selective inhibitors. Semin Thromb Hemost 1992; 18: 135-49.
-
(1992)
Semin Thromb Hemost
, vol.18
, pp. 135-149
-
-
Hijikata-Okunomiya, A.1
Okamoto, S.2
-
22
-
-
0020471223
-
Anticoagulant and antithrombotic ettects of some protease inhibitors
-
Leipzig
-
Mattson C, Eriksson E, Nilsson S. Anticoagulant and antithrombotic ettects of some protease inhibitors. Folia Haematol (Leipzig) 1982; 109: S 43-51.
-
(1982)
Folia Haematol
, vol.109
-
-
Mattson, C.1
Eriksson, E.2
Nilsson, S.3
-
23
-
-
2642604217
-
Melagatran, an oral active site inhibitor of thrombin, prevents or delays formation of electrically-induced occlusive thrombus in the canine coronary artery
-
accepted
-
Metha JL, Chen L, Mattsson C, Gustafsson D, Saldeen TGP. Melagatran, an oral active site inhibitor of thrombin, prevents or delays formation of electrically-induced occlusive thrombus in the canine coronary artery. J Cardiovasc Pharmacol, accepted.
-
J Cardiovasc Pharmacol
-
-
Metha, J.L.1
Chen, L.2
Mattsson, C.3
Gustafsson, D.4
Saldeen, T.G.P.5
-
24
-
-
0342565213
-
Pharmacokinetics of inogatran, a new low molecular weight thrombin inhibitor, in rats and dogs
-
Abstract 1605
-
Pharmacokinetics of inogatran, a new low molecular weight thrombin inhibitor, in rats and dogs. Eriksson UG, Renberg L, Vedin C, Strimfors M. Thromb Haemost 1995; 73: 1318 (Abstract 1605).
-
(1995)
Thromb Haemost
, vol.73
, pp. 1318
-
-
Eriksson, U.G.1
Renberg, L.2
Vedin, C.3
Strimfors, M.4
-
25
-
-
0026639844
-
Inhibition by D-MePhe-Pro-Arg-H (GYKI-14766) of thrombus growth in experimental models of thrombosis
-
Bagdy D. Szabó G, Barabás É, Bajusz S. Inhibition by D-MePhe-Pro-Arg-H (GYKI-14766) of thrombus growth in experimental models of thrombosis. Thromb Haemost 1992; 68: 125-9.
-
(1992)
Thromb Haemost
, vol.68
, pp. 125-129
-
-
Bagdy, D.1
Szabó, G.2
Barabás, É.3
Bajusz, S.4
-
26
-
-
0025950323
-
Anticoagulant activity of a peptide boronic acid thrombin inhibitor by various routes of administration
-
Hussain MA, Knabb R, Aungst BJ, Kettner C. Anticoagulant activity of a peptide boronic acid thrombin inhibitor by various routes of administration. Peptides 1991; 12: 1153-4.
-
(1991)
Peptides
, vol.12
, pp. 1153-1154
-
-
Hussain, M.A.1
Knabb, R.2
Aungst, B.J.3
Kettner, C.4
-
27
-
-
0029044322
-
Purification and characterization of TAFI, a thrombin-activatable fibrinolysis inhibitor
-
Bajzar L, Manuel R, Nesheim ME. Purification and characterization of TAFI, a thrombin-activatable fibrinolysis inhibitor. J Biol Chem 1995; 270: 14477-84.
-
(1995)
J Biol Chem
, vol.270
, pp. 14477-14484
-
-
Bajzar, L.1
Manuel, R.2
Nesheim, M.E.3
-
28
-
-
0027965921
-
Fibrin in human plasma: Gel architectures governed by rate and nature of fibrinogen activation
-
Blombäck B, Carlsson K, Fatah K, Hessel B, Procyk R. Fibrin in human plasma: gel architectures governed by rate and nature of fibrinogen activation. Thromb Res 1994; 75: 521-38.
-
(1994)
Thromb Res
, vol.75
, pp. 521-538
-
-
Blombäck, B.1
Carlsson, K.2
Fatah, K.3
Hessel, B.4
Procyk, R.5
-
29
-
-
0029100827
-
Effect of fibrin structure on plasmin-mediated dissolution of plasma dots
-
Carr ME, Alving BM. Effect of fibrin structure on plasmin-mediated dissolution of plasma dots. Blood Coagul Fibrinol 1995; 6: 567-73.
-
(1995)
Blood Coagul Fibrinol
, vol.6
, pp. 567-573
-
-
Carr, M.E.1
Alving, B.M.2
-
30
-
-
0030663858
-
Hirudin and melagatran, a reversible, low molecular weight thrombin inhibitor, as adjunctive agents to tissue type plasminogen activator in a canine model of coronary artery thrombolysis
-
Mattsson C, Björkman JA, Ulvinge JC. Hirudin and melagatran, a reversible, low molecular weight thrombin inhibitor, as adjunctive agents to tissue type plasminogen activator in a canine model of coronary artery thrombolysis. Fibrinol Proteol 1997; 11: 121-8.
-
(1997)
Fibrinol Proteol
, vol.11
, pp. 121-128
-
-
Mattsson, C.1
Björkman, J.A.2
Ulvinge, J.C.3
|