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Volumn 299, Issue 3, 2010, Pages

Thujone, a component of medicinal herbs, rescues palmitate-induced insulin resistance in skeletal muscle

Author keywords

Acetyl CoA carboxylase; Adenosine 5 monophosphate kinase; Glucose transport; Palmitate oxidation

Indexed keywords

ABSINTHOL; ACETYL COENZYME A CARBOXYLASE; ADENYLATE KINASE; GLUCOSE; GLUCOSE TRANSPORTER 4; INSULIN; PALMITIC ACID; BETA-THUJONE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; LOC686547 PROTEIN, RAT; SLC2A4 PROTEIN, RAT; TERPENE;

EID: 77956678082     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00216.2010     Document Type: Article
Times cited : (38)

References (67)
  • 1
    • 0036292507 scopus 로고    scopus 로고
    • Investigation on the hypoglycaemic effects of extracts of four Mexican medicinal plants in normal and alloxan-diabetic mice
    • DOI 10.1002/ptr.914
    • Alarcon-Aguilar FJ, Roman-Ramos R, Flores-Saenz JL, Aguirre-Garcia F. Investigation on the hypoglycaemic effects of extracts of four Mexican medicinal plants in normal and alloxan-diabetic mice. Phytother Res 16: 383-386, 2002. (Pubitemid 34700279)
    • (2002) Phytotherapy Research , vol.16 , Issue.4 , pp. 383-386
    • Alarcon-Aguilar, F.J.1    Roman-Ramos, R.2    Flores-Saenz, J.L.3    Aguirre-Garcia, F.4
  • 3
    • 70350455737 scopus 로고    scopus 로고
    • Restoring As160 phosphorylation rescues skeletal muscle insulin resistance and fatty acid oxidation while not reducing intramuscular lipids
    • Alkhateeb H, Chabowski A, Glatz JF, Gurd B, Luiken JJ, Bonen A. Restoring As160 phosphorylation rescues skeletal muscle insulin resistance and fatty acid oxidation while not reducing intramuscular lipids. Am J Physiol Endocrinol Metab 297: E1056-E1066, 2009.
    • (2009) Am J Physiol Endocrinol Metab , vol.297
    • Alkhateeb, H.1    Chabowski, A.2    Glatz, J.F.3    Gurd, B.4    Luiken, J.J.5    Bonen, A.6
  • 4
    • 34548448413 scopus 로고    scopus 로고
    • Two phases of palmitate-induced insulin resistance in skeletal muscle: Impaired GLUT4 translocation is followed by a reduced GLUT4 intrinsic activity
    • DOI 10.1152/ajpendo.00685.2006
    • Alkhateeb H, Chabowski A, Glatz JF, Luiken JF, Bonen A. Two phases of palmitate-induced insulin resistance in skeletal muscle: impaired GLUT4 translocation is followed by a reduced GLUT4 intrinsic activity. Am J Physiol Endocrinol Metab 293: E783-E793, 2007. (Pubitemid 47358991)
    • (2007) American Journal of Physiology - Endocrinology and Metabolism , vol.293 , Issue.3
    • Alkhateeb, H.1    Chabowski, A.2    Glatz, J.F.C.3    Luiken, J.F.P.4    Bonen, A.5
  • 5
    • 53649108513 scopus 로고    scopus 로고
    • Antioxidant activity of some Jordanian medicinal plants used traditionally for treatment of diabetes
    • Al-Mustafa AH, and Al-Thunibat OY. Antioxidant activity of some Jordanian medicinal plants used traditionally for treatment of diabetes. Pak J Biol Sci 11: 351-358, 2008.
    • (2008) Pak J Biol Sci , vol.11 , pp. 351-358
    • Al-Mustafa, A.H.1    Al-Thunibat, O.Y.2
  • 6
    • 40949134115 scopus 로고    scopus 로고
    • Rosiglitazone increases fatty acid oxidation and fatty acid translocase (FAT/CD36) but not carnitine palmitoyltransferase I in rat muscle mitochondria
    • DOI 10.1113/jphysiol.2007.146563
    • Benton CR, Holloway GP, Campbell SE, Yoshida Y, Tandon NN, Glatz JF, Luiken JJ, Spriet LL, Bonen A. Rosiglitazone increases fatty acid oxidation and fatty acid translocase (FAT/CD36) but not carnitine palmitoyltransferase I in rat muscle mitochondria. J Physiol 586: 1755-1766, 2008. (Pubitemid 351404973)
    • (2008) Journal of Physiology , vol.586 , Issue.6 , pp. 1755-1766
    • Benton, C.R.1    Holloway, G.P.2    Campbell, S.E.3    Yoshida, Y.4    Tandon, N.N.5    Glatz, J.F.C.6    Luiken, J.J.J.F.P.7    Spriet, L.L.8    Bonen, A.9
  • 7
    • 0037643536 scopus 로고    scopus 로고
    • Effects of free fatty acids (FFA) on glucose metabolism: Significance for insulin resistance and type 2 diabetes
    • DOI 10.1055/s-2003-39781
    • Boden G. Effects of free fatty acids (FFA) on glucose metabolism: significance for insulin resistance and type 2 diabetes. Exp Clin Endocrinol Diabetes 111: 121-124, 2003. (Pubitemid 36682048)
    • (2003) Experimental and Clinical Endocrinology and Diabetes , vol.111 , Issue.3 , pp. 121-124
    • Boden, G.1
  • 8
    • 0032935817 scopus 로고    scopus 로고
    • Muscle contractile activity increases fatty acid metabolism and transport and FAT/CD36
    • Bonen A, Dyck DJ, Ibrahimi A, Abumrad NA. Muscle contractile activity increases fatty acid metabolism and transport and FAT/CD36. Am J Physiol Endocrinol Metab 276: E642-E649, 1999.
    • (1999) Am J Physiol Endocrinol Metab , vol.276
    • Bonen, A.1    Dyck, D.J.2    Ibrahimi, A.3    Abumrad, N.A.4
  • 10
    • 34948909040 scopus 로고    scopus 로고
    • Antimicrobial and antioxidant properties of Rosemary and Sage (Rosmarinus officinalis L. and Salvia officinalis L., Lamiaceae) essential oils
    • DOI 10.1021/jf0715323
    • Bozin B, Mimica-Dukic N, Samojlik I, Jovin E. Antimicrobial and antioxidant properties of rosemary and sage (Rosmarinus officinalis L. and Salvia officinalis L, Lamiaceae) essential oils. J Agric Food Chem 55: 7879-7885, 2007. (Pubitemid 47522202)
    • (2007) Journal of Agricultural and Food Chemistry , vol.55 , Issue.19 , pp. 7879-7885
    • Bozin, B.1    Mimica-Dukic, N.2    Samojlik, I.3    Jovin, E.4
  • 12
    • 62749140758 scopus 로고    scopus 로고
    • Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance
    • Bruce CR, Hoy AJ, Turner N, Watt MJ, Allen TL, Carpenter K, Cooney GJ, Febbraio MA, Kraegen EW. Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance. Diabetes 58: 550-558, 2009.
    • (2009) Diabetes , vol.58 , pp. 550-558
    • Bruce, C.R.1    Hoy, A.J.2    Turner, N.3    Watt, M.J.4    Allen, T.L.5    Carpenter, K.6    Cooney, G.J.7    Febbraio, M.A.8    Kraegen, E.W.9
  • 13
    • 0038045416 scopus 로고    scopus 로고
    • Hypoglycaemic and antioxidant effects of onion, Allium cepa: Dietary onion addition, antioxidant activity and hypoglycaemic effects on diabetic rats
    • Campos KE, Diniz YS, Cataneo AC, Faine LA, Alves MJ, Novelli EL. Hypoglycaemic and antioxidant effects of onion, Allium cepa: dietary onion addition, antioxidant activity and hypoglycaemic effects on diabetic rats. Int J Food Sci Nutr 54: 241-246, 2003.
    • (2003) Int J Food Sci Nutr , vol.54 , pp. 241-246
    • Campos, K.E.1    Diniz, Y.S.2    Cataneo, A.C.3    Faine, L.A.4    Alves, M.J.5    Novelli, E.L.6
  • 14
    • 14544271907 scopus 로고    scopus 로고
    • AMP-activated protein kinase: Balancing the scales
    • DOI 10.1016/j.biochi.2004.10.017
    • Carling D. AMP-activated protein kinase: balancing the scales. Biochimie 87: 87-91, 2005. (Pubitemid 40298770)
    • (2005) Biochimie , vol.87 , Issue.1 SPEC. ISS , pp. 87-91
    • Carling, D.1
  • 15
    • 34547438354 scopus 로고    scopus 로고
    • Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose transport
    • Cartee GD, Wojtaszewski JF. Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose transport. Appl Physiol Nutr Metab 32: 557-566, 2007.
    • (2007) Appl Physiol Nutr Metab , vol.32 , pp. 557-566
    • Cartee, G.D.1    Wojtaszewski, J.F.2
  • 16
    • 30044448374 scopus 로고    scopus 로고
    • Direct metabolic regulation in skeletal muscle and fat tissue by leptin: Implications for glucose and fatty acids homeostasis
    • Lond
    • Ceddia RB. Direct metabolic regulation in skeletal muscle and fat tissue by leptin: implications for glucose and fatty acids homeostasis. Int J Obes (Lond) 29: 1175-1183, 2005.
    • (2005) Int J Obes , vol.29 , pp. 1175-1183
    • Ceddia, R.B.1
  • 17
    • 0037385896 scopus 로고    scopus 로고
    • Bitter melon (Momordica charantia) reduces adiposity, lowers serum insulin and normalizes glucose tolerance in rats fed a high fat diet
    • Chen Q, Chan LL, Li ET. Bitter melon (Momordica charantia) reduces adiposity, lowers serum insulin and normalizes glucose tolerance in rats fed a high fat diet. J Nutr 133: 1088-1093, 2003. (Pubitemid 36407130)
    • (2003) Journal of Nutrition , vol.133 , Issue.4 , pp. 1088-1093
    • Chen, Q.1    Chan, L.L.Y.2    Li, E.T.S.3
  • 18
    • 2942580733 scopus 로고    scopus 로고
    • Covalent activation of heart AMP-activated protein kinase in response to physiological concentrations of long-chain fatty acids
    • DOI 10.1111/j.1432-1033.2004.04151.x
    • Clark H, Carling D, Saggerson D. Covalent activation of heart AMP-activated protein kinase in response to physiological concentrations of long-chain fatty acids. Eur J Biochem 271: 2215-2224, 2004. (Pubitemid 38747990)
    • (2004) European Journal of Biochemistry , vol.271 , Issue.11 , pp. 2215-2224
    • Clark, H.1    Carling, D.2    Saggerson, D.3
  • 19
    • 42949109650 scopus 로고    scopus 로고
    • Impaired skeletal muscle substrate oxidation in glucose-intolerant men improves after weight loss
    • DOI 10.1038/oby.2008.24, PII OBY200824
    • Corpeleijn E, Mensink M, Kooi ME, Roekaerts PM, Saris WH, Blaak EE. Impaired skeletal muscle substrate oxidation in glucose-intolerant men improves after weight loss. Obesity (Silver Spring) 16: 1025-1032, 2008. (Pubitemid 351620467)
    • (2008) Obesity , vol.16 , Issue.5 , pp. 1025-1032
    • Corpeleijn, E.1    Mensink, M.2    Kooi, M.E.3    Roekaerts, P.M.H.J.4    Saris, W.H.M.5    Blaak, E.E.6
  • 21
    • 23944490690 scopus 로고    scopus 로고
    • Effect of Salvia officinalis L. leaves on serum glucose and insulin in healthy and streptozotocin-induced diabetic rats
    • DOI 10.1016/j.jep.2005.03.008, PII S0378874105002254
    • Eidi M, Eidi A, Zamanizadeh H. Effect of Salvia officinalis L. leaves on serum glucose and insulin in healthy and streptozotocin-induced diabetic rats. J Ethnopharmacol 100: 310-313, 2005. (Pubitemid 41206627)
    • (2005) Journal of Ethnopharmacology , vol.100 , Issue.3 , pp. 310-313
    • Eidi, M.1    Eidi, A.2    Zamanizadeh, H.3
  • 22
    • 34548617275 scopus 로고    scopus 로고
    • Chemical composition and antifungal activity of the essential oils of three species of Artemisia on some soil-borne phytopathogens
    • Farzaneh M, Ahmadzadeh M, Hadian J, Tehrani AS. Chemical composition and antifungal activity of the essential oils of three species of Artemisia on some soil-borne phytopathogens. Commun Agric Appl Biol Sci 71: 1327-1333, 2006.
    • (2006) Commun Agric Appl Biol Sci , vol.71 , pp. 1327-1333
    • Farzaneh, M.1    Ahmadzadeh, M.2    Hadian, J.3    Tehrani, A.S.4
  • 23
    • 33244493944 scopus 로고    scopus 로고
    • Regulation of AMP-activated protein kinase and acetyl-CoA carboxylase phosphorylation by palmitate in skeletal muscle cells
    • DOI 10.1194/jlr.M500438-JLR200
    • Fediuc S, Gaidhu MP, Ceddia RB. Regulation of AMP-activated protein kinase and acetyl-CoA carboxylase phosphorylation by palmitate in skeletal muscle cells. J Lipid Res 47: 412-420, 2006. (Pubitemid 43276927)
    • (2006) Journal of Lipid Research , vol.47 , Issue.2 , pp. 412-420
    • Fediuc, S.1    Gaidhu, M.P.2    Ceddia, R.B.3
  • 24
    • 2942538292 scopus 로고    scopus 로고
    • Pharmacological actions and potential uses of Momordica charantia: A review
    • Grover JK, Yadav SP. Pharmacological actions and potential uses of Momordica charantia: a review. J Ethnopharmacol 93: 123-132, 2004.
    • (2004) J Ethnopharmacol , vol.93 , pp. 123-132
    • Grover, J.K.1    Yadav, S.P.2
  • 25
    • 33847072201 scopus 로고    scopus 로고
    • AMP-activated protein kinase as a drug target
    • DOI 10.1146/annurev.pharmtox.47.120505.105304
    • Hardie DG. AMP-activated protein kinase as a drug target. Annu Rev Pharmacol Toxicol 47: 185-210, 2007. (Pubitemid 46272128)
    • (2007) Annual Review of Pharmacology and Toxicology , vol.47 , pp. 185-210
    • Hardie, D.G.1
  • 26
    • 0342902202 scopus 로고    scopus 로고
    • Detoxification of alpha- and beta-Thujones (the active ingredients of absinthe): Site specificity and species differences in cytochrome P450 oxidation in vitro and in vivo
    • Hold KM, Sirisoma NS, Casida JE. Detoxification of alpha- and beta-Thujones (the active ingredients of absinthe): site specificity and species differences in cytochrome P450 oxidation in vitro and in vivo. Chem Res Toxicol 14: 589-595, 2001.
    • (2001) Chem Res Toxicol , vol.14 , pp. 589-595
    • Hold, K.M.1    Sirisoma, N.S.2    Casida, J.E.3
  • 27
    • 58149394230 scopus 로고    scopus 로고
    • Regulation of skeletal muscle mitochondrial fatty acid metabolism in lean and obese individuals
    • Holloway GP, Bonen A, Spriet LL. Regulation of skeletal muscle mitochondrial fatty acid metabolism in lean and obese individuals. Am J Clin Nutr 89: 455S-462S, 2009.
    • (2009) Am J Clin Nutr , vol.89
    • Holloway, G.P.1    Bonen, A.2    Spriet, L.L.3
  • 30
    • 0037040185 scopus 로고    scopus 로고
    • Mechanism for fatty acid ";sparing" effect on glucose-induced transcription: Regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase
    • DOI 10.1074/jbc.M107895200
    • Kawaguchi T, Osatomi K, Yamashita H, Kabashima T, Uyeda K. Mechanism for fatty acid "sparing" effect on glucose-induced transcription: regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase. J Biol Chem 277: 3829-3835, 2002. (Pubitemid 34968632)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.6 , pp. 3829-3835
    • Kawaguchi, T.1    Osatomi, K.2    Yamashita, H.3    Kabashima, T.4    Uyeda, K.5
  • 31
    • 70349131219 scopus 로고    scopus 로고
    • Activation of AMP-activated protein kinase by interleukin-6 in rat skeletal muscle: Association with changes in cAMP, energy state, and endogenous fuel mobilization
    • Kelly M, Gauthier MS, Saha AK, Ruderman NB. Activation of AMP-activated protein kinase by interleukin-6 in rat skeletal muscle: association with changes in cAMP, energy state, and endogenous fuel mobilization. Diabetes 58: 1953-1960, 2009.
    • (2009) Diabetes , vol.58 , pp. 1953-1960
    • Kelly, M.1    Gauthier, M.S.2    Saha, A.K.3    Ruderman, N.B.4
  • 32
    • 0242600806 scopus 로고    scopus 로고
    • 5-Amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes
    • DOI 10.2337/diabetes.52.5.1066
    • Koistinen HA, Galuska D, Chibalin AV, Yang J, Zierath JR, Holman GD, Wallberg-Henriksson H. 5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes. Diabetes 52: 1066-1072, 2003. (Pubitemid 36523338)
    • (2003) Diabetes , vol.52 , Issue.5 , pp. 1066-1072
    • Koistinen, H.A.1    Galuska, D.2    Chibalin, A.V.3    Yang, J.4    Zierath, J.R.5    Holman, G.D.6    Wallberg-Henriksson, H.7
  • 34
    • 43249083481 scopus 로고    scopus 로고
    • Free fatty acids and skeletal muscle insulin resistance
    • DOI 10.1097/01.mol.0000319118.44995.9a, PII 0004143320080600000004
    • Kraegen EW, Cooney GJ. Free fatty acids and skeletal muscle insulin resistance. Curr Opin Lipidol 19: 235-241, 2008. (Pubitemid 351653560)
    • (2008) Current Opinion in Lipidology , vol.19 , Issue.3 , pp. 235-241
    • Kraegen, E.W.1    Cooney, G.J.2
  • 35
    • 67651214381 scopus 로고    scopus 로고
    • In vivo imaging of GLUT4 translocation
    • Lauritzen HP. In vivo imaging of GLUT4 translocation. Appl Physiol Nutr Metab 34: 420-423, 2009.
    • (2009) Appl Physiol Nutr Metab , vol.34 , pp. 420-423
    • Lauritzen, H.P.1
  • 36
    • 0033979604 scopus 로고    scopus 로고
    • The transferrin receptor defines two distinct contraction-responsive GLUT4 vesicle populations in skeletal muscle
    • Lemieux K, Han X, Dombrowski L, Bonen A, Marette A. The transferrin receptor defines two distinct contraction-responsive GLUT4 vesicle populations in skeletal muscle. Diabetes 49: 183-189, 2000. (Pubitemid 30070995)
    • (2000) Diabetes , vol.49 , Issue.2 , pp. 183-189
    • Lemieux, K.1    Han, X.-X.2    Dombrowski, L.3    Bonen, A.4    Marette, A.5
  • 37
    • 58849135877 scopus 로고    scopus 로고
    • Thiazolidinediones: Do harms outweigh benefits?
    • Lipscombe LL. Thiazolidinediones: do harms outweigh benefits? CMAJ 180: 16-17, 2009.
    • (2009) CMAJ , vol.180 , pp. 16-17
    • Lipscombe, L.L.1
  • 38
    • 49149091400 scopus 로고    scopus 로고
    • In vitro inhibitory activities of plants used in Lebanon traditional medicine against angiotensin converting enzyme (ACE) and digestive enzymes related to diabetes
    • Loizzo MR, Saab AM, Tundis R, Menichini F, Bonesi M, Piccolo V, Statti GA, de Cindio B, Houghton PJ. In vitro inhibitory activities of plants used in Lebanon traditional medicine against angiotensin converting enzyme (ACE) and digestive enzymes related to diabetes. J Ethnopharmacol 119: 109-116, 2008.
    • (2008) J Ethnopharmacol , vol.119 , pp. 109-116
    • Loizzo, M.R.1    Saab, A.M.2    Tundis, R.3    Menichini, F.4    Bonesi, M.5    Piccolo, V.6    Statti, G.A.7    De Cindio, B.8    Houghton, P.J.9
  • 39
    • 42749096543 scopus 로고    scopus 로고
    • Screening of chemical composition, antimicrobial and antioxidant activities of Artemisia essential oils
    • Lopes-Lutz D, Alviano DS, Alviano CS, Kolodziejczyk PP. Screening of chemical composition, antimicrobial and antioxidant activities of Artemisia essential oils. Phytochemistry 69: 1732-1738, 2008.
    • (2008) Phytochemistry , vol.69 , pp. 1732-1738
    • Lopes-Lutz, D.1    Alviano, D.S.2    Alviano, C.S.3    Kolodziejczyk, P.P.4
  • 40
    • 34247263686 scopus 로고    scopus 로고
    • Chemical diversity of the biological active ingredients of salvia officinalis and some closely related species
    • Mathe I, Hohmann J, Janicsak G, Nagy G, Dora R. [Chemical diversity of the biological active ingredients of salvia officinalis and some closely related species]. Acta Pharm Hung 77: 37-45, 2007.
    • (2007) Acta Pharm Hung , vol.77 , pp. 37-45
    • Mathe, I.1    Hohmann, J.2    Janicsak, G.3    Nagy, G.4    Dora, R.5
  • 41
    • 34249313005 scopus 로고    scopus 로고
    • The role of AMP kinase in diabetes
    • Misra P, Chakrabarti R. The role of AMP kinase in diabetes. Indian J Med Res 125: 389-398, 2007.
    • (2007) Indian J Med Res , vol.125 , pp. 389-398
    • Misra, P.1    Chakrabarti, R.2
  • 43
    • 0036635769 scopus 로고    scopus 로고
    • Targeting the AMP-activated protein kinase for the treatment of type 2 diabetes
    • Musi N, Goodyear LJ. Targeting the AMP-activated protein kinase for the treatment of type 2 diabetes. Curr Drug Targets Immune Endocr Metabol Disord 2: 119-127, 2002.
    • (2002) Curr Drug Targets Immune Endocr Metabol Disord , vol.2 , pp. 119-127
    • Musi, N.1    Goodyear, L.J.2
  • 44
    • 0036838494 scopus 로고    scopus 로고
    • AMP kinase activation ameliorates insulin resistance induced by free fatty acids in rat skeletal muscle
    • Olsen GS, Hansen BF. AMP kinase activation ameliorates insulin resistance induced by free fatty acids in rat skeletal muscle. Am J Physiol Endocrinol Metab 283: E965-E970, 2002.
    • (2002) Am J Physiol Endocrinol Metab , vol.283
    • Olsen, G.S.1    Hansen, B.F.2
  • 45
    • 51449103367 scopus 로고    scopus 로고
    • Prolonged exposure to palmitate impairs fatty acid oxidation despite activation of AMP-activated protein kinase in skeletal muscle cells
    • Pimenta AS, Gaidhu MP, Habib S, So M, Fediuc S, Mirpourian M, Musheev M, Curi R, Ceddia RB. Prolonged exposure to palmitate impairs fatty acid oxidation despite activation of AMP-activated protein kinase in skeletal muscle cells. J Cell Physiol 217: 478-485, 2008.
    • (2008) J Cell Physiol , vol.217 , pp. 478-485
    • Pimenta, A.S.1    Gaidhu, M.P.2    Habib, S.3    So, M.4    Fediuc, S.5    Mirpourian, M.6    Musheev, M.7    Curi, R.8    Ceddia, R.B.9
  • 47
    • 4544242908 scopus 로고    scopus 로고
    • Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells
    • DOI 10.1042/BJ20040139
    • Powell DJ, Turban S, Gray A, Hajduch E, Hundal HS. Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells. Biochem J 382: 619-629, 2004. (Pubitemid 39243928)
    • (2004) Biochemical Journal , vol.382 , Issue.2 , pp. 619-629
    • Powell, D.J.1    Turban, S.2    Gray, A.3    Hajduch, E.4    Hundal, H.S.5
  • 48
    • 34548549048 scopus 로고    scopus 로고
    • Composition of the essential oil of Salvia officinalis L. from various European countries
    • DOI 10.1080/14786410500528478, PII 778296713
    • Raal A, Orav A, Arak E. Composition of the essential oil of Salvia officinalis L. from various European countries. Nat Prod Res 21: 406-411, 2007. (Pubitemid 47386414)
    • (2007) Natural Product Research , vol.21 , Issue.5 , pp. 406-411
    • Raal, A.1    Orav, A.2    Arak, E.3
  • 49
    • 33749395733 scopus 로고    scopus 로고
    • A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160
    • DOI 10.1074/jbc.M603274200
    • Ramm G, Larance M, Guilhaus M, James DE. A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160. J Biol Chem 281: 29174-29180, 2006. (Pubitemid 44507061)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.39 , pp. 29174-29180
    • Ramm, G.1    Larance, M.2    Guilhaus, M.3    James, D.E.4
  • 50
    • 0035449518 scopus 로고    scopus 로고
    • Glucose, exercise and insulin: Emerging concepts
    • DOI 10.1111/j.1469-7793.2001.t01-2-00313.x
    • Richter EA, Derave W, Wojtaszewski JF. Glucose, exercise and insulin: emerging concepts. J Physiol 535: 313-322, 2001. (Pubitemid 32825671)
    • (2001) Journal of Physiology , vol.535 , Issue.2 , pp. 313-322
    • Richter, E.A.1    Derave, W.2    Wojtaszewski, J.F.P.3
  • 51
    • 61449106744 scopus 로고    scopus 로고
    • AMPK and the biochemistry of exercise: Implications for human health and disease
    • Richter EA, Ruderman NB. AMPK and the biochemistry of exercise: implications for human health and disease. Biochem J 418: 261-275, 2009.
    • (2009) Biochem J , vol.418 , pp. 261-275
    • Richter, E.A.1    Ruderman, N.B.2
  • 52
    • 34248581989 scopus 로고    scopus 로고
    • Disordered lipid metabolism and the pathogenesis of insulin resistance
    • DOI 10.1152/physrev.00024.2006
    • Savage DB, Petersen KF, Shulman GI. Disordered lipid metabolism and the pathogenesis of insulin resistance. Physiol Rev 87: 507-520, 2007. (Pubitemid 47084679)
    • (2007) Physiological Reviews , vol.87 , Issue.2 , pp. 507-520
    • Savage, D.B.1    Petersen, K.F.2    Shulman, G.I.3
  • 53
    • 33749479230 scopus 로고    scopus 로고
    • AMP-activated protein kinase: Role in metabolism and therapeutic implications
    • DOI 10.1111/j.1463-1326.2005.00561.x
    • Schimmack G, Defronzo RA, Musi N. AMP-activated protein kinase: Role in metabolism and therapeutic implications. Diabetes Obes Metab 8: 591-602, 2006. (Pubitemid 44515556)
    • (2006) Diabetes, Obesity and Metabolism , vol.8 , Issue.6 , pp. 591-602
    • Schimmack, G.1    DeFronzo, R.A.2    Musi, N.3
  • 54
    • 3242726981 scopus 로고    scopus 로고
    • Hypoglycaemic effects of myrtle oil in normal and alloxan-diabetic rabbits
    • DOI 10.1016/j.jep.2004.03.049, PII S0378874104001801
    • Sepici A, Gurbuz I, Cevik C, Yesilada E. Hypoglycaemic effects of myrtle oil in normal and alloxan-diabetic rabbits. J Ethnopharmacol 93: 311-318, 2004. (Pubitemid 38962422)
    • (2004) Journal of Ethnopharmacology , vol.93 , Issue.2-3 , pp. 311-318
    • Sepici, A.1    Gurbuz, I.2    Cevik, C.3    Yesilada, E.4
  • 55
    • 33947181508 scopus 로고    scopus 로고
    • Effects of in vivo antioxidant enzyme activities of myrtle oil in normoglycaemic and alloxan diabetic rabbits
    • DOI 10.1016/j.jep.2006.10.015, PII S0378874106005307
    • Sepici-Dincel A, Acikgoz S, Cevik C, Sengelen M, Yesilada E. Effects of in vivo antioxidant enzyme activities of myrtle oil in normoglycaemic and alloxan diabetic rabbits. J Ethnopharmacol 110: 498-503, 2007. (Pubitemid 46394595)
    • (2007) Journal of Ethnopharmacology , vol.110 , Issue.3 , pp. 498-503
    • Sepici-Dincel, A.1    Acikgoz, S.2    Cevik, C.3    Sengelen, M.4    Yesilada, E.5
  • 56
    • 0141459344 scopus 로고    scopus 로고
    • High-fat diet and leptin treatment alter skeletal muscle insulin-stimulated phosphatidylinositol 3-kinase activity and glucose transport
    • DOI 10.1016/S0026-0495(03)00158-6
    • Singh MK, Krisan AD, Crain AM, Collins DE, Yaspelkis BB, 3rd. High-fat diet and leptin treatment alter skeletal muscle insulin-stimulated phosphatidylinositol 3-kinase activity and glucose transport. Metabolism 52: 1196-1205, 2003. (Pubitemid 37203495)
    • (2003) Metabolism: Clinical and Experimental , vol.52 , Issue.9 , pp. 1196-1205
    • Singh, M.K.1    Krisan, A.D.2    Crain, A.M.3    Collins, D.E.4    Yaspelkis III, B.B.5
  • 57
    • 0034877808 scopus 로고    scopus 로고
    • alpha- and beta-Thujones (herbal medicines and food additives): Synthesis and analysis of hydroxy and dehydro metabolites
    • Sirisoma NS, Hold KM, Casida JE. alpha- and beta-Thujones (herbal medicines and food additives): synthesis and analysis of hydroxy and dehydro metabolites. J Agric Food Chem 49: 1915-1921, 2001.
    • (2001) J Agric Food Chem , vol.49 , pp. 1915-1921
    • Sirisoma, N.S.1    Hold, K.M.2    Casida, J.E.3
  • 58
    • 67650914230 scopus 로고    scopus 로고
    • AMPK in health and disease
    • Steinberg GR, Kemp BE. AMPK in health and disease. Physiol Rev 89: 1025-1078, 2009.
    • (2009) Physiol Rev , vol.89 , pp. 1025-1078
    • Steinberg, G.R.1    Kemp, B.E.2
  • 59
    • 14844355093 scopus 로고    scopus 로고
    • Effects of a novel formulation of essential oils on glucose-insulin metabolism in diabetic and hypertensive rats: A pilot study
    • DOI 10.1111/j.1463-1326.2004.00386.x
    • Talpur N, Echard B, Ingram C, Bagchi D, Preuss H. Effects of a novel formulation of essential oils on glucose-insulin metabolism in diabetic and hypertensive rats: a pilot study. Diabetes Obes Metab 7: 193-199, 2005. (Pubitemid 40352734)
    • (2005) Diabetes, Obesity and Metabolism , vol.7 , Issue.2 , pp. 193-199
    • Talpur, N.1    Echard, B.2    Ingram, C.3    Bagchi, D.4    Preuss, H.G.5
  • 60
    • 1542347594 scopus 로고    scopus 로고
    • In vitro antimicrobial and antioxidant activities of the essential oils and various extracts of Thymus eigii M. Zohary et P. H. Davis
    • Tepe B, Daferera D, Sokmen M, Polissiou M, Sokmen A. In vitro antimicrobial and antioxidant activities of the essential oils and various extracts of Thymus eigii M. Zohary et P. H. Davis. J Agric Food Chem 52: 1132-1137, 2004.
    • (2004) J Agric Food Chem , vol.52 , pp. 1132-1137
    • Tepe, B.1    Daferera, D.2    Sokmen, M.3    Polissiou, M.4    Sokmen, A.5
  • 61
  • 63
    • 42949084209 scopus 로고    scopus 로고
    • Muscular diacylglycerol metabolism and insulin resistance
    • DOI 10.1016/j.physbeh.2007.12.002, PII S0031938407004945
    • Timmers S, Schrauwen P, de Vogel J. Muscular diacylglycerol metabolism and insulin resistance. Physiol Behav 94: 242-251, 2008. (Pubitemid 351615425)
    • (2008) Physiology and Behavior , vol.94 , Issue.2 , pp. 242-251
    • Timmers, S.1    Schrauwen, P.2    De Vogel, J.3
  • 64
    • 0033550319 scopus 로고    scopus 로고
    • Natural products with hypoglycemic, hypotensive, hypocholesterolemic, antiatherosclerotic and antithrombotic activities
    • Wang HX, Ng TB. Natural products with hypoglycemic, hypotensive, hypocholesterolemic, antiatherosclerotic and antithrombotic activities. Life Sci 65: 2663-2677, 1999.
    • (1999) Life Sci , vol.65 , pp. 2663-2677
    • Wang, H.X.1    Ng, T.B.2
  • 65
    • 52649123679 scopus 로고    scopus 로고
    • Role of fatty acids in the development of insulin resistance and type 2 diabetes mellitus
    • Wolf G. Role of fatty acids in the development of insulin resistance and type 2 diabetes mellitus. Nutr Rev 66: 597-600, 2008.
    • (2008) Nutr Rev , vol.66 , pp. 597-600
    • Wolf, G.1
  • 66
  • 67
    • 65349177200 scopus 로고    scopus 로고
    • AMPK: An emerging drug target for diabetes and the metabolic syndrome
    • Zhang BB, Zhou G, Li C. AMPK: an emerging drug target for diabetes and the metabolic syndrome. Cell Metab 9: 407-416, 2009.
    • (2009) Cell Metab , vol.9 , pp. 407-416
    • Zhang, B.B.1    Zhou, G.2    Li, C.3


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