Detoxification of α- and β-thujones (the active ingredients of absinthe): Site specificity and species differences in cytochrome P450 oxidation in vitro and in vivo

Chemical Research in Toxicology

Volumn 14, Issue 5, 2001, Pages 589-595

  Höld, Karin M ^a   Sirisoma, Nilantha S ^a   Casida, John E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; ABSINTHOL; BETA THUYONE; CHLORIDE CHANNEL; CYTOCHROME P450; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ABSINTHE; ANIMAL CELL; ARTICLE; DETOXIFICATION; DROSOPHILA MELANOGASTER; DRUG ACTIVITY; DRUG GLUCURONIDATION; DRUG METABOLISM; HUMAN; HUMAN CELL; HYDROXYLATION; LIVER MICROSOME; MOUSE; NONHUMAN; RAT; SPECIES DIFFERENCE;

ABSINTHE; ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; CYTOCHROME P-450 ENZYME SYSTEM; DROSOPHILA; HUMANS; HYDROXYLATION; METABOLIC DETOXICATION, DRUG; MICE; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; MONOTERPENES; OXIDATION-REDUCTION; PROTEIN BINDING; RATS; RECEPTORS, GABA-A; RECOMBINANT PROTEINS; SPECIES SPECIFICITY; SUBSTRATE SPECIFICITY; TERPENES;

ANIMALIA; DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0342902202     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx000242c     Document Type: Article

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