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Volumn 21, Issue 9, 2010, Pages 1468-1476

Trps1 haploinsufficiency promotes renal fibrosis by increasing Arkadia expression

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; OSTEOGENIC PROTEIN 1; PROTEIN ARKADIA; SMAD3 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; RNF111 PROTEIN, MOUSE; SMAD3 PROTEIN, MOUSE; SMAD7 PROTEIN, MOUSE; TRANSCRIPTION FACTOR GATA; TRPS1 PROTEIN, MOUSE; UBIQUITIN PROTEIN LIGASE; VILLIN;

EID: 77956553923     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2009121201     Document Type: Article
Times cited : (39)

References (37)
  • 3
    • 0034785496 scopus 로고    scopus 로고
    • Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis
    • Yang J, Liu Y: Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am J Pathol 159: 1465-1475, 2001 (Pubitemid 32947976)
    • (2001) American Journal of Pathology , vol.159 , Issue.4 , pp. 1465-1475
    • Yang, J.1    Liu, Y.2
  • 4
    • 0346724511 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and its implications for fibrosis
    • DOI 10.1172/JCI200320530
    • Kalluri R, Neilson EG: Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 112: 1776-1784, 2003 (Pubitemid 38063698)
    • (2003) Journal of Clinical Investigation , vol.112 , Issue.12 , pp. 1776-1784
    • Kalluri, R.1    Neilson, E.G.2
  • 5
    • 0032842887 scopus 로고    scopus 로고
    • Transforming growth factor-beta regulates tubular epithelial- myofibroblast transdifferentiation in vitro
    • DOI 10.1046/j.1523-1755.1999.00656.x
    • Fan JM, Ng YY, Hill PA, Nikolic-Paterson DJ, Mu W, Atkins RC, Lan HY: Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro. Kidney Int 56: 1455-1467, 1999 (Pubitemid 29451252)
    • (1999) Kidney International , vol.56 , Issue.4 , pp. 1455-1467
    • Fan, J.-M.1    Yee-Yung, N.G.2    Hill, P.A.3    Nikolic-Paterson, D.J.4    Mu, W.5    Atkins, R.C.6    Lan, H.Y.7
  • 6
    • 0346727324 scopus 로고    scopus 로고
    • Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
    • DOI 10.1172/JCI200319270
    • Sato M, Muragaki Y, Saika S, Roberts AB, Ooshima A: Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest 112: 1486-1494, 2003 (Pubitemid 38056275)
    • (2003) Journal of Clinical Investigation , vol.112 , Issue.10 , pp. 1486-1494
    • Sato, M.1    Muragaki, Y.2    Saika, S.3    Roberts, A.B.4    Ooshima, A.5
  • 7
  • 8
    • 65249099522 scopus 로고    scopus 로고
    • Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice
    • Chung AC, Huang XR, Zhou L, Heuchel R, Lai KN, Lan HY: Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice. Nephrol Dial Transplant 24: 1443-1454, 2009
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 1443-1454
    • Chung, A.C.1    Huang, X.R.2    Zhou, L.3    Heuchel, R.4    Lai, K.N.5    Lan, H.Y.6
  • 11
    • 0032442852 scopus 로고    scopus 로고
    • Smads: Transcriptional activators of TGF-beta responses
    • DOI 10.1016/S0092-8674(00)81696-7
    • Derynck R, Zhang Y, Feng XH: Smads: Transcriptional activators of TGF-beta responses. Cell 95: 737-740, 1998 (Pubitemid 29014453)
    • (1998) Cell , vol.95 , Issue.6 , pp. 737-740
    • Derynck, R.1    Zhang, Y.2    Feng, X.-H.3
  • 13
    • 0034065822 scopus 로고    scopus 로고
    • Ubiquitin-mediated proteolysis: Biological regulation via destruction
    • DOI 10.1002/(SICI)1521-1878(200005)22:5<442::AID-BIES6>3.0.CO;2-Q
    • Ciechanover A, Orian A, Schwartz AL: Ubiquitin-mediated proteolysis: Biological regulation via destruction. Bioessays 22: 442-451, 2000 (Pubitemid 30308270)
    • (2000) BioEssays , vol.22 , Issue.5 , pp. 442-451
    • Ciechanover, A.1    Orian, A.2    Schwartz, A.L.3
  • 15
    • 0034517389 scopus 로고    scopus 로고
    • Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGFbeta receptor for degradation
    • DOI 10.1016/S1097-2765(00)00134-9
    • Kavsak P, Rasmussen RK, Causing CG, Bonni S, Zhu H, Thomsen GH, Wrana JL: Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation. Mol Cell 6: 1365-1375, 2000 (Pubitemid 32045929)
    • (2000) Molecular Cell , vol.6 , Issue.6 , pp. 1365-1375
    • Kavsak, P.1    Rasmussen, R.K.2    Causing, C.G.3    Bonni, S.4    Zhu, H.5    Thomsen, G.H.6    Wrana, J.L.7
  • 16
    • 0035918274 scopus 로고    scopus 로고
    • Smurf1 Interacts with Transforming Growth Factor-beta Type I Receptor through Smad7 and Induces Receptor Degradation
    • DOI 10.1074/jbc.C100008200
    • Ebisawa T, Fukuchi M, Murakami G, Chiba T, Tanaka K, Imamura T, Miyazono K: Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation. J Biol Chem 276: 12477-12480, 2001 (Pubitemid 37385151)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.16 , pp. 12477-12480
    • Ebisawa, T.1    Fukuchi, M.2    Murakami, G.3    Chiba, T.4    Tanaka, K.5    Imamura, T.6    Miyazono, K.7
  • 19
    • 42649120148 scopus 로고    scopus 로고
    • Smad7 as a therapeutic agent for chronic kidney diseases
    • DOI 10.2741/3057
    • Lan HY: Smad7 as a therapeutic agent for chronic kidney diseases. Front Biosci 13: 4984-4992, 2008 (Pubitemid 351599652)
    • (2008) Frontiers in Bioscience , vol.13 , Issue.13 , pp. 4984-4992
    • Hui, Y.L.1
  • 23
    • 2542609844 scopus 로고    scopus 로고
    • Smad3 as a mediator of the fibrotic response
    • Flanders KC: Smad3 as a mediator of the fibrotic response. Int J Exp Pathol 85: 47-64, 2004
    • (2004) Int J Exp Pathol , vol.85 , pp. 47-64
    • Flanders, K.C.1
  • 24
    • 0036014928 scopus 로고    scopus 로고
    • Smad7 inhibits fibrotic effect of TGF-beta on renal tubular epithelial cells by blocking Smad2 activation
    • Li JH, Zhu HJ, Huang XR, Lai KN, Johnson RJ, Lan HY: Smad7 inhibits fibrotic effect of TGF-beta on renal tubular epithelial cells by blocking Smad2 activation. J Am Soc Nephrol 13: 1464-1472, 2002
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1464-1472
    • Li, J.H.1    Zhu, H.J.2    Huang, X.R.3    Lai, K.N.4    Johnson, R.J.5    Lan, H.Y.6
  • 25
    • 0034646674 scopus 로고    scopus 로고
    • Smad3 and Smad4 mediate transcriptional activation of the human Smad7 promoter by transforming growth factor beta
    • DOI 10.1074/jbc.275.15.11320
    • von Gersdorff G, Susztak K, Rezvani F, Bitzer M, Liang D, Bottinger EP: Smad3 and Smad4 mediate transcriptional activation of the human Smad7 promoter by transforming growth factor beta. J Biol Chem 275: 11320-11326, 2000 (Pubitemid 30212781)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.15 , pp. 11320-11326
    • Von Gersdorff, G.1    Susztak, K.2    Rezvani, F.3    Bitzer, M.4    Liang, D.5    Bottinger, E.P.6
  • 26
    • 0033584854 scopus 로고    scopus 로고
    • Regulation of Smad7 promoter by direct association with Smad3 and Smad4
    • Nagarajan RP, Zhang J, Li W, Chen Y: Regulation of Smad7 promoter by direct association with Smad3 and Smad4. J Biol Chem 274: 33412-33418, 1999 (Pubitemid 129511646)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.47 , pp. 33412-33418
    • Nagarajan, R.P.1    Zhang, J.2    Li, W.3    Chen, Y.4
  • 27
    • 39349094176 scopus 로고    scopus 로고
    • Arkadia regulates TGF-beta signaling during renal tubular epithelial to mesenchymal cell transition
    • DOI 10.1038/sj.ki.5002713, PII 5002713
    • Liu FY, Li XZ, Peng YM, Liu H, Liu YH: Arkadia regulates TGF-beta signaling during renal tubular epithelial to mesenchymal cell transition. Kidney Int 73: 588-594, 2008 (Pubitemid 351264107)
    • (2008) Kidney International , vol.73 , Issue.5 , pp. 588-594
    • Liu, F.-Y.1    Li, X.-Z.2    Peng, Y.-M.3    Liu, H.4    Liu, Y.-H.5
  • 28
    • 34247098372 scopus 로고    scopus 로고
    • Arkadia-Smad7-mediated positive regulation of TGF-beta signaling in a rat model of tubulointerstitial fibrosis
    • DOI 10.1159/000100518
    • Liu FY, Li XZ, Peng YM, Liu H, Liu YH: Arkadia-Smad7-mediated positive regulation of TGF-beta signaling in a rat model of tubulointerstitial fibrosis. Am J Nephrol 27: 176-183, 2007 (Pubitemid 46588184)
    • (2007) American Journal of Nephrology , vol.27 , Issue.2 , pp. 176-183
    • Liu, F.-Y.1    Li, X.-Z.2    Peng, Y.-M.3    Liu, H.4    Liu, Y.-H.5
  • 30
    • 0038717407 scopus 로고    scopus 로고
    • BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
    • DOI 10.1038/nm888
    • Zeisberg M, Hanai J, Sugimoto H, Mammoto T, Charytan D, Strutz F, Kalluri R: BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat Med 9: 964-968, 2003 (Pubitemid 36889942)
    • (2003) Nature Medicine , vol.9 , Issue.7 , pp. 964-968
    • Zeisberg, M.1    Hanai, J.-I.2    Sugimoto, H.3    Mammoto, T.4    Charytan, D.5    Strutz, F.6    Kalluri, R.7
  • 32
    • 54749083116 scopus 로고    scopus 로고
    • Heme oxygenase-1 deficiency promotes epithelial-mesenchymal transition and renal fibrosis
    • Kie JH, Kapturczak MH, Traylor A, Agarwal A, Hill-Kapturczak N: Heme oxygenase-1 deficiency promotes epithelial-mesenchymal transition and renal fibrosis. J Am Soc Nephrol 19: 1681-1691, 2008
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1681-1691
    • Kie, J.H.1    Kapturczak, M.H.2    Traylor, A.3    Agarwal, A.4    Hill-Kapturczak, N.5
  • 34
    • 0030000689 scopus 로고    scopus 로고
    • A novel method of microwave treatment for detection of cytoplasmic and nuclear antigens by flow cytometry
    • DOI 10.1016/0022-1759(95)00233-2
    • Lan HY, Hutchinson P, Tesch GH, Mu W, Atkins RC: A novel method of microwave treatment for detection of cytoplasmic and nuclear antigens by flow cytometry. J Immunol Methods 190: 1-10, 1996 (Pubitemid 26099973)
    • (1996) Journal of Immunological Methods , vol.190 , Issue.1 , pp. 1-10
    • Lan, H.Y.1    Hutchinson, P.2    Tesch, G.H.3    Mu, W.4    Atkins, R.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.