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Volumn 8, Issue 9, 2010, Pages 967-972

Can your genes make you more prone to pneumococcal disease?

Author keywords

mannose binding lectin; nuclear factor B; polymorphism; PTPN22; Streptococcus pneumoniae; Toll like receptors

Indexed keywords

I KAPPA B; I KAPPA B KINASE; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; MANNOSE BINDING LECTIN; MYELOID DIFFERENTIATION FACTOR 88; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 22; TOLL LIKE RECEPTOR;

EID: 77956476845     PISSN: 14787210     EISSN: 17448336     Source Type: Journal    
DOI: 10.1586/eri.10.84     Document Type: Editorial
Times cited : (5)

References (83)
  • 1
    • 9744261123 scopus 로고    scopus 로고
    • Pneumococcal vaccines
    • World Health Organization
    • World Health Organization. Pneumococcal vaccines. Wkly Epidemiol. Rec. 14, 110-119 (2003).
    • (2003) Wkly Epidemiol. Rec. , vol.14 , pp. 110-119
  • 2
    • 0035654187 scopus 로고    scopus 로고
    • BTS guidelines for the management of community-acquired pneumonia in adults
    • British Thoracic Society Standards of Care Committee
    • British Thoracic Society Standards of Care Committee. BTS guidelines for the management of community-acquired pneumonia in adults. Thorax 56(Suppl. IV), iv1-iv64 (2001).
    • (2001) Thorax , vol.56 , Issue.SUPPL. IV
  • 3
    • 1442299471 scopus 로고    scopus 로고
    • Streptococcus pneumoniae colonisation: The key to pneumococcal disease
    • DOI 10.1016/S1473-3099(04)00938-7, PII S1473309904009387
    • Bogaert D, de Groot R, Hermans PWM. Streptococcus pneumoniae colonisation: the key to pneumococcal disease. Lancet Infect. Dis. 4, 144-154 (2004). (Pubitemid 38293138)
    • (2004) Lancet Infectious Diseases , vol.4 , Issue.3 , pp. 144-154
    • Bogaert, D.1    De Groot, R.2    Hermans, P.W.M.3
  • 4
    • 27744526668 scopus 로고    scopus 로고
    • Streptococcus pneumoniae
    • Principles and Practice of Infectious Disease Mandell GL, Bennett JE, Dolin R (Eds.)
    • Musher DM. Streptococcus pneumoniae. In: Principles and Practice of Infectious Disease. Mandell GL, Bennett JE, Dolin R (Eds.). Churchill Livingstone, PA, USA, 2392-2411 (2004).
    • (2004) Churchill Livingstone, PA, USA , pp. 2392-2411
    • Musher, D.M.1
  • 5
    • 18744382834 scopus 로고    scopus 로고
    • Asthma as a risk factor for invasive pneumococcal disease
    • Talbot TR, Hartert TV, Mitchel E et al Asthma as a risk factor for invasive pneumococcal disease. N. Engl. J. Med. 352, 2082-2090 (2005).
    • (2005) N. Engl. J. Med. , vol.352 , pp. 2082-2090
    • Talbot, T.R.1    Hartert, T.V.2    Mitchel, E.3
  • 6
    • 0036183180 scopus 로고    scopus 로고
    • The burden of invasive pneumococcal disease and the potential for reduction by immunisation
    • Parsons HK, Dockrell DH. The burden of invasive pneumococcal disease and the potential for reduction by immunisation. Int. J. Antimicrob. Agents 19, 85-93 (2002).
    • (2002) Int. J. Antimicrob. Agents , vol.19 , pp. 85-93
    • Parsons, H.K.1    Dockrell, D.H.2
  • 8
    • 0035653671 scopus 로고    scopus 로고
    • Genetics of susceptibility to human infectious disease
    • Cooke GC, Hill AVS. Genetics of susceptibility to human infectious disease. Nat. Rev. Genet. 2, 967-977 (2001).
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 967-977
    • Cooke, G.C.1    Avs, H.2
  • 9
    • 0041626891 scopus 로고    scopus 로고
    • Genetic variability in response to infection: Malaria and after
    • Weatherall DJ, Clegg JB. Genetic variability in response to infection: malaria and after. Genes Immun. 3, 331-337 (2002).
    • (2002) Genes Immun. , vol.3 , pp. 331-337
    • Weatherall, D.J.1    Clegg, J.B.2
  • 10
    • 0023870774 scopus 로고
    • Genetic and environmental infuences on premature death in adult adoptees
    • Sorensen TIA, Nielsen GG, Andersen PK, Teasdale TW. Genetic and environmental infuences on premature death in adult adoptees. N. Engl. J. Med. 318, 727-732 (1988).
    • (1988) N. Engl. J. Med. , vol.318 , pp. 727-732
    • Tia, S.1    Nielsen, G.G.2    Andersen, P.K.3    Teasdale, T.W.4
  • 11
    • 0035168473 scopus 로고    scopus 로고
    • Role of genetic resistance in invasive pneumococcal infection: Identifcation and study of susceptibility and resistance in inbred mouse strains
    • Gingles NA, Alexander JE, Kadioglu A et al. Role of genetic resistance in invasive pneumococcal infection: identifcation and study of susceptibility and resistance in inbred mouse strains. Infect. Immun. 69(1), 426-434 (2001).
    • (2001) Infect. Immun. , vol.69 , Issue.1 , pp. 426-434
    • Gingles, N.A.1    Alexander, J.E.2    Kadioglu, A.3
  • 12
    • 0036182433 scopus 로고    scopus 로고
    • Role of infammatory mediators in resistance and susceptibility to pneumococcal infection
    • Kerr AR, Irvine JJ, Search JJ et al. Role of infammatory mediators in resistance and susceptibility to pneumococcal infection. Infect. Immun. 70(3), 1547-1557 (2002).
    • (2002) Infect. Immun. , vol.70 , Issue.3 , pp. 1547-1557
    • Kerr, A.R.1    Irvine, J.J.2    Search, J.J.3
  • 15
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S, Takeda K. Toll-like receptor signalling. Nat. Rev. Immunol. 4, 499-511 (2004).
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 17
    • 0033168728 scopus 로고    scopus 로고
    • Recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2
    • Yoshimura A, Lien E, Ingalls RR, Tuomanen E, Dziarski R, Golenbock D. Recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2. J. Immunol. 163(1), 1-5 (1999).
    • (1999) J. Immunol. , vol.163 , Issue.1 , pp. 1-5
    • Yoshimura, A.1    Lien, E.2    Ingalls, R.R.3    Tuomanen, E.4    Dziarski, R.5    Golenbock, D.6
  • 18
    • 0038182550 scopus 로고    scopus 로고
    • Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved
    • Schroder NW, Morath S, Alexander C et al. Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved. J. Biol. Chem. 278, 15587-15594 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 15587-15594
    • Schroder, N.W.1    Morath, S.2    Alexander, C.3
  • 19
    • 33748846770 scopus 로고    scopus 로고
    • Live Streptococcus pneumoniae, Haemophilus infuenzae, and Neisseria meningitides activate the infammatory response through Toll-like receptors 2, 4, and 9 in species-specifc patterns
    • Mogensen TH, Paludan SR, Kilian M, Ostergaard L. Live Streptococcus pneumoniae, Haemophilus infuenzae, and Neisseria meningitides activate the infammatory response through Toll-like receptors 2, 4, and 9 in species-specifc patterns. J. Leukocyte Biol. 80, 1-11 (2006).
    • (2006) J. Leukocyte Biol. , vol.80 , pp. 1-11
    • Mogensen, T.H.1    Paludan, S.R.2    Kilian, M.3    Ostergaard, L.4
  • 20
    • 28444461458 scopus 로고    scopus 로고
    • Toll-like receptor 2 defciency delays pneumococcal phagocytosis and impairs oxidative killing by granulocytes
    • Letiembre M, Echchannaoui H, Bachmann P et al. Toll-like receptor 2 defciency delays pneumococcal phagocytosis and impairs oxidative killing by granulocytes. Infect. Immun. 73, 8397-8401 (2005).
    • (2005) Infect. Immun. , vol.73 , pp. 8397-8401
    • Letiembre, M.1    Echchannaoui, H.2    Bachmann, P.3
  • 21
    • 0037452778 scopus 로고    scopus 로고
    • Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection
    • Malley R, Henneke P, Morse SC et al. Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection. Proc. Natl Acad. Sci. USA 100(4), 1966-1971 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , Issue.4 , pp. 1966-1971
    • Malley, R.1    Henneke, P.2    Morse, S.C.3
  • 22
    • 0029886855 scopus 로고    scopus 로고
    • Pneumococcal cell wall activates NF-KB in human monocytes: Aspects distinct from endotoxin
    • Spellerberg B, Rosenow C, Sha W, Tuomanen EI. Pneumococcal cell wall activates NF-KB in human monocytes: aspects distinct from endotoxin. Microb. Pathog 20, 309-317 (1996).
    • (1996) Microb. Pathog , vol.20 , pp. 309-317
    • Spellerberg, B.1    Rosenow, C.2    Sha, W.3    Tuomanen, E.I.4
  • 23
    • 19944422390 scopus 로고    scopus 로고
    • Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleuin-8 promoter
    • Schmeck B, Zahlten J, Moog K et al Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleuin-8 promoter. J. Biol. Chem. 279(51), 53241-53247 (2004).
    • (2004) J. Biol. Chem. , vol.279 , Issue.51 , pp. 53241-53247
    • Schmeck, B.1    Zahlten, J.2    Moog, K.3
  • 24
    • 0033623338 scopus 로고    scopus 로고
    • Nuclear factor-KB activation in mouse lung lavage cells in response to Streptococcus pneumoniae pulmonary infection
    • Amory-Rivier CF, Mohler J, Bedos JP et al Nuclear factor-KB activation in mouse lung lavage cells in response to Streptococcus pneumoniae pulmonary infection. Crit. Care Med. 28(9), 3249-3256 (2000).
    • (2000) Crit. Care Med. , vol.28 , Issue.9 , pp. 3249-3256
    • Amory-Rivier, C.F.1    Mohler, J.2    Bedos, J.P.3
  • 25
    • 28244495191 scopus 로고    scopus 로고
    • Lung NF-KB activation and neutrophils recruitment require IL-1 and TNF receptor signaling during pneumococcal pneumonia
    • Jones MR, Simms BT, Lupa MM, Kogan MS, Mizgerd JP. Lung NF-KB activation and neutrophils recruitment require IL-1 and TNF receptor signaling during pneumococcal pneumonia. J. Immunol. 175, 7530-7535 (2005).
    • (2005) J. Immunol. , vol.175 , pp. 7530-7535
    • Jones, M.R.1    Simms, B.T.2    Lupa, M.M.3    Kogan, M.S.4    Mizgerd, J.P.5
  • 26
    • 33846525046 scopus 로고    scopus 로고
    • Functions and regulation of NF-KB RelA during pneumococcal pneumonia
    • Quinton LJ, Jones MR, Simms BT et al Functions and regulation of NF-KB RelA during pneumococcal pneumonia. J. Immunol. 178, 1896-1903 (2007).
    • (2007) J. Immunol. , vol.178 , pp. 1896-1903
    • Quinton, L.J.1    Jones, M.R.2    Simms, B.T.3
  • 27
    • 48749109290 scopus 로고    scopus 로고
    • Pyogenic bacterial infections in humans with MyD88 defciency
    • Von Bernuth H, Picard C, Jin Z et al. Pyogenic bacterial infections in humans with MyD88 defciency. Science 321(5889), 691-696 (2008).
    • (2008) Science , vol.321 , Issue.5889 , pp. 691-696
    • Von Bernuth, H.1    Picard, C.2    Jin, Z.3
  • 28
    • 0033658369 scopus 로고    scopus 로고
    • A novel X-linked disorder of immune defciency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-y (NEMO)
    • Zonana J, Elder ME, Schneider LC et al. A novel X-linked disorder of immune defciency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-y (NEMO). Am. J. Hum. Genet. 67, 1555-1562 (2000).
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 1555-1562
    • Zonana, J.1    Elder, M.E.2    Schneider, L.C.3
  • 29
    • 0035281865 scopus 로고    scopus 로고
    • Incontinentia pigmenti in a surviving male is accompanied by hypohidrotic ectodermal dysplasia and recurrent infection
    • Mansour S, Woffendin H, Mitton S et al Incontinentia pigmenti in a surviving male is accompanied by hypohidrotic ectodermal dysplasia and recurrent infection. Am. J. Med. Genet. 99, 172-177 (2001).
    • (2001) Am. J. Med. Genet. , vol.99 , pp. 172-177
    • Mansour, S.1    Woffendin, H.2    Mitton, S.3
  • 30
    • 0035093630 scopus 로고    scopus 로고
    • X-linked anhidrotic ectodermal dysplasia with immunodefciency is caused by impaired NF-KB signaling
    • Doffnger R, Smahi A, Bessia C et al X-linked anhidrotic ectodermal dysplasia with immunodefciency is caused by impaired NF-KB signaling. Nat. Genet. 27, 277-285 (2001).
    • (2001) Nat. Genet. , vol.27 , pp. 277-285
    • Doffnger, R.1    Smahi, A.2    Bessia, C.3
  • 31
    • 0037471003 scopus 로고    scopus 로고
    • Pyogenic bacterial infections in humans with IRAK-4 defciency
    • Picard C, Puel A, Bonnet M et al. Pyogenic bacterial infections in humans with IRAK-4 defciency. Science 299, 2076-2079 (2003).
    • (2003) Science , vol.299 , pp. 2076-2079
    • Picard, C.1    Puel, A.2    Bonnet, M.3
  • 32
    • 85047693559 scopus 로고    scopus 로고
    • A hypermorphic IKBa mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodefciency
    • Courtois G, Smahi A, Reichenbach J et al A hypermorphic IKBa mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodefciency. J. Clin. Invest. 112, 1108-1115 (2003).
    • (2003) J. Clin. Invest. , vol.112 , pp. 1108-1115
    • Courtois, G.1    Smahi, A.2    Reichenbach, J.3
  • 33
    • 4544219780 scopus 로고    scopus 로고
    • The same IkBa mutation in two related individuals leads to completely different clinical syndromes
    • Janssen R, van Wengen A, Hoeve MA et al The same IkBa mutation in two related individuals leads to completely different clinical syndromes. J. Exp. Med. 200, 559-568 (2004).
    • (2004) J. Exp. Med. , vol.200 , pp. 559-568
    • Janssen, R.1    Van Wengen, A.2    Hoeve, M.A.3
  • 35
    • 0043281537 scopus 로고    scopus 로고
    • Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysaccharide and interleukin-1 in a patient with recurrent bacterial infections
    • Medvedev AE, Lentschat A, Kuhns DB et al. Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysaccharide and interleukin-1 in a patient with recurrent bacterial infections. J. Exp. Med. 198, 521-531 (2003).
    • (2003) J. Exp. Med. , vol.198 , pp. 521-531
    • Medvedev, A.E.1    Lentschat, A.2    Kuhns, D.B.3
  • 37
    • 77953122866 scopus 로고    scopus 로고
    • NFKBIZ polymorphisms and susceptibility to pneumococcal disease in European and African populations
    • Chapman SJ, Khor CC, Vannberg FO et al. NFKBIZ polymorphisms and susceptibility to pneumococcal disease in European and African populations. Genes Immun. 11(4), 319-325 (2010).
    • (2010) Genes Immun. , vol.11 , Issue.4 , pp. 319-325
    • Chapman, S.J.1    Khor, C.C.2    Vannberg, F.O.3
  • 38
    • 27744520921 scopus 로고    scopus 로고
    • Alterations in cell signaling in sepsis
    • Abraham E. Alterations in cell signaling in sepsis. Clin. Infect. Dis. 41, S459-S464 (2005).
    • (2005) Clin. Infect. Dis. , vol.41
    • Abraham, E.1
  • 39
    • 0033790833 scopus 로고    scopus 로고
    • Pharmacological interference with NF-kB activation attenuates central nervous system complications in experimental pneumococcal meningitis
    • Koedel U, Bayerlein I, Paul R, Sporer B, Pfster HW. Pharmacological interference with NF-kB activation attenuates central nervous system complications in experimental pneumococcal meningitis. J. Infect. Dis. 182, 1437-1445 (2000).
    • (2000) J. Infect. Dis. , vol.182 , pp. 1437-1445
    • Koedel, U.1    Bayerlein, I.2    Paul, R.3    Sporer, B.4    Pfster, H.W.5
  • 40
    • 0034746919 scopus 로고    scopus 로고
    • NF-kB: A key role in infammatory diseases
    • Tak PP, Firestein GS. NF-kB: a key role in infammatory diseases. J. Clin. Invest. 107(1), 7-11 (2001).
    • (2001) J. Clin. Invest. , vol.107 , Issue.1 , pp. 7-11
    • Tak, P.P.1    Firestein, G.S.2
  • 41
    • 0346505340 scopus 로고    scopus 로고
    • The IKK NF-kB system: A treasure trove for drug development
    • Karin M, Yamamoto Y, Wang QM. The IKK NF-kB system: a treasure trove for drug development. Nat. Rev. Drug Discov. 3, 17-26 (2003).
    • (2003) Nat. Rev. Drug Discov. , vol.3 , pp. 17-26
    • Karin, M.1    Yamamoto, Y.2    Wang, Q.M.3
  • 42
    • 0037153191 scopus 로고    scopus 로고
    • Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4
    • Yamamoto M, Sato S, Hemmi H et al. Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. Nature 420, 324-329 (2002).
    • (2002) Nature , vol.420 , pp. 324-329
    • Yamamoto, M.1    Sato, S.2    Hemmi, H.3
  • 43
    • 34047098731 scopus 로고    scopus 로고
    • A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis
    • Khor CC, Chapman SJ, Vannberg FO et al. A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis. Nat. Genet. 39(4), 523-528 (2007).
    • (2007) Nat. Genet. , vol.39 , Issue.4 , pp. 523-528
    • Khor, C.C.1    Chapman, S.J.2    Vannberg, F.O.3
  • 44
    • 67649880546 scopus 로고    scopus 로고
    • Functional and genetic evidence that the Mal/TIRAP allele variant 180L has been selected by providing protection against septic shock
    • Ferwerda B, Alonso S, Banahan K et al Functional and genetic evidence that the Mal/TIRAP allele variant 180L has been selected by providing protection against septic shock. Proc. Natl Acad. Sci. USA 106(25), 10272-10277 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , Issue.25 , pp. 10272-10277
    • Ferwerda, B.1    Alonso, S.2    Banahan, K.3
  • 47
    • 0029165459 scopus 로고
    • Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor
    • Cundell DR, Gerard NP, GerardC, Idanpaan-Heikkila I, Tuomanen EI. Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor. Nature 377, 435-438 (1995).
    • (1995) Nature , vol.377 , pp. 435-438
    • Cundell, D.R.1    Gerard, N.P.2    Gerard, C.3    Idanpaan-Heikkila, I.4    Tuomanen, E.I.5
  • 48
    • 0345550400 scopus 로고    scopus 로고
    • Impact of mannose-binding lectin on susceptibility to infectious diseases
    • Eisen DP, Minchinton RM. Impact of mannose-binding lectin on susceptibility to infectious diseases. Clin. Infect. Dis. 37, 1496-1505 (2003).
    • (2003) Clin. Infect. Dis. , vol.37 , pp. 1496-1505
    • Eisen, D.P.1    Minchinton, R.M.2
  • 49
    • 0037093083 scopus 로고    scopus 로고
    • Mannose-binding lectin gene polymorphisms are associated with major infection following allogeneic hemopoietic stem cell transplantation
    • Mullighan CG, Heatley S, Doherty K et al. Mannose-binding lectin gene polymorphisms are associated with major infection following allogeneic hemopoietic stem cell transplantation. Blood 99, 3524-3529 (2002).
    • (2002) Blood , vol.99 , pp. 3524-3529
    • Mullighan, C.G.1    Heatley, S.2    Doherty, K.3
  • 50
    • 0037136413 scopus 로고    scopus 로고
    • Mannan-binding lectin: Clinical signifcance and applications
    • Kilpatrick DC. Mannan-binding lectin: clinical signifcance and applications. Biochim. Biophys. Acta 1572, 401-413 (2002).
    • (2002) Biochim. Biophys. Acta , vol.1572 , pp. 401-413
    • Kilpatrick, D.C.1
  • 51
    • 0030986151 scopus 로고    scopus 로고
    • Association of mutations in mannose binding protein gene with childhood infection in consecutive hospital series
    • Summerfeld JA, Sumiya M, Levin M et al. Association of mutations in mannose binding protein gene with childhood infection in consecutive hospital series. Br. Med. J. 314, 1229-1232 (1997).
    • (1997) Br. Med. J. , vol.314 , pp. 1229-1232
    • Summerfeld, J.A.1    Sumiya, M.2    Levin, M.3
  • 52
    • 0037018768 scopus 로고    scopus 로고
    • MBL genotype and risk of invasive pneumococcal disease: A case-control study
    • Roy S, Knox K, Segal S et al. MBL genotype and risk of invasive pneumococcal disease: a case-control study. Lancet 359, 1569-1573 (2002).
    • (2002) Lancet , vol.359 , pp. 1569-1573
    • Roy, S.1    Knox, K.2    Segal, S.3
  • 53
    • 0037068967 scopus 로고    scopus 로고
    • Mannose-binding lectin genotype as a risk factor for invasive pneumococcal infection
    • Kronborg G, Garred P. Mannose-binding lectin genotype as a risk factor for invasive pneumococcal infection. Lancet 360, 1176 (2002).
    • (2002) Lancet , vol.360 , pp. 1176
    • Kronborg, G.1    Garred, P.2
  • 54
    • 0033608862 scopus 로고    scopus 로고
    • Association of variants of the gene for mannose-binding lectin with susceptibility to meningococcal disease
    • Hibberd ML, Sumiya M, Summerfeld JA et al. Association of variants of the gene for mannose-binding lectin with susceptibility to meningococcal disease. Lancet 353, 1049-1053 (1999).
    • (1999) Lancet , vol.353 , pp. 1049-1053
    • Hibberd, M.L.1    Sumiya, M.2    Summerfeld, J.A.3
  • 55
    • 0035857775 scopus 로고    scopus 로고
    • Acute respiratory tract infections and mannose-binding lectin insuffciency during early childhood
    • Koch A, Melbye M, Sorensen P et al. Acute respiratory tract infections and mannose-binding lectin insuffciency during early childhood. JAMA 285, 1316-1321 (2001).
    • (2001) JAMA , vol.285 , pp. 1316-1321
    • Koch, A.1    Melbye, M.2    Sorensen, P.3
  • 56
    • 0242551989 scopus 로고    scopus 로고
    • Association of mannose-binding lectin polymorphisms with sepsis and fatal outcome, in patients with systemic infammatory response syndrome
    • Garred P, Strom JJ, Quist L et al. Association of mannose-binding lectin polymorphisms with sepsis and fatal outcome, in patients with systemic infammatory response syndrome. J. Infect. Dis. 188, 1394-1403 (2003).
    • (2003) J. Infect. Dis. , vol.188 , pp. 1394-1403
    • Garred, P.1    Strom, J.J.2    Quist, L.3
  • 57
    • 0035949119 scopus 로고    scopus 로고
    • Association between defciency of mannose-binding lectin and severe infections after chemotherapy
    • Peterslund NA, Koch C, Jensenius JC et al. Association between defciency of mannose-binding lectin and severe infections after chemotherapy. Lancet 358, 636-638 (2001).
    • (2001) Lancet , vol.358 , pp. 636-638
    • Peterslund, N.A.1    Koch, C.2    Jensenius, J.C.3
  • 58
    • 0035949107 scopus 로고    scopus 로고
    • Defciency of mannose-binding lectin and burden of infection in children with malignancy: A prospective study
    • Neth O, Hann I, Turner MW et al. Defciency of mannose-binding lectin and burden of infection in children with malignancy: a prospective study. Lancet 358, 614-618 (2001).
    • (2001) Lancet , vol.358 , pp. 614-618
    • Neth, O.1    Hann, I.2    Turner, M.W.3
  • 59
    • 48349147408 scopus 로고    scopus 로고
    • Mannose-binding lectin and mannose-binding lectin-associated serine protease 2 in susceptibility, severity, and outcome of pneumonia in adults
    • Garcia-Laorden MI, Sole-Violan J, Rodriguez de Castro F et al. Mannose-binding lectin and mannose-binding lectin-associated serine protease 2 in susceptibility, severity, and outcome of pneumonia in adults. J. Allergy Clin. Immunol. 122(2), 368-374 (2008).
    • (2008) J. Allergy Clin. Immunol. , vol.122 , Issue.2 , pp. 368-374
    • Garcia-Laorden, M.I.1    Sole-Violan, J.2    Rodriguez De Castro, F.3
  • 60
    • 57349143352 scopus 로고    scopus 로고
    • Mannose-binding lectin genotypes in susceptibility to community acquired pneumonia
    • Endeman H, Herpers BL, de Jong BA et al. Mannose-binding lectin genotypes in susceptibility to community acquired pneumonia. Chest 134(6), 1135-1140 (2008).
    • (2008) Chest , vol.134 , Issue.6 , pp. 1135-1140
    • Endeman, H.1    Herpers, B.L.2    De Jong, B.A.3
  • 61
    • 54749146284 scopus 로고    scopus 로고
    • Mannose-binding lectin concentrations, MBL2 polymorphisms, and susceptibility to respiratory tract infections in young men
    • Rantala A, Lajunen T, Juvonen R et al. Mannose-binding lectin concentrations, MBL2 polymorphisms, and susceptibility to respiratory tract infections in young men. J. Infect. Dis. 198(8), 1247-1253 (2008).
    • (2008) J. Infect. Dis. , vol.198 , Issue.8 , pp. 1247-1253
    • Rantala, A.1    Lajunen, T.2    Juvonen, R.3
  • 62
    • 48749126099 scopus 로고    scopus 로고
    • Low serum mannose-binding lectin level increases the risk of death due to pneumococcal infection
    • Eisen DP, Dean MM, Boermeester MA et al. Low serum mannose-binding lectin level increases the risk of death due to pneumococcal infection. Clin. Infect. Dis. 47(4), 510-516 (2008).
    • (2008) Clin. Infect. Dis. , vol.47 , Issue.4 , pp. 510-516
    • Eisen, D.P.1    Dean, M.M.2    Boermeester, M.A.3
  • 64
    • 12144291502 scopus 로고    scopus 로고
    • A functional variant of lymphoid tyrosine phosphatase is associated with type i diabetes
    • Bottini N, Musumeci L, Alonso A et al. A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat. Genet. 36, 337-338 (2004).
    • (2004) Nat. Genet. , vol.36 , pp. 337-338
    • Bottini, N.1    Musumeci, L.2    Alonso, A.3
  • 66
    • 3242713277 scopus 로고    scopus 로고
    • A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis
    • Begovich AB, Carlton VE, Honigberg LA et al. A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am. J. Hum. Genet. 75, 330-337 (2004).
    • (2004) Am. J. Hum. Genet. , vol.75 , pp. 330-337
    • Begovich, A.B.1    Carlton, V.E.2    Honigberg, L.A.3
  • 67
    • 4143105691 scopus 로고    scopus 로고
    • Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE
    • Kyogoku C, Langefeld CD, Ortmann WA et al. Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. Am. J. Hum. Genet. 75, 504-507 (2004).
    • (2004) Am. J. Hum. Genet. , vol.75 , pp. 504-507
    • Kyogoku, C.1    Langefeld, C.D.2    Ortmann, W.A.3
  • 68
    • 25444483876 scopus 로고    scopus 로고
    • PTPN22 genetic variation: Evidence for multiple variants associated with rheumatoid arthritis
    • Carlton VEH, Hu X, Chokkalingam AP et al. PTPN22 genetic variation: evidence for multiple variants associated with rheumatoid arthritis. Am. J. Hum. Genet. 7 7, 567-581 (2005).
    • (2005) Am. J. Hum. Genet. , vol.7 , Issue.7 , pp. 567-581
    • Veh, C.1    Hu, X.2    Chokkalingam, A.P.3
  • 69
    • 7044253358 scopus 로고    scopus 로고
    • Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus
    • Smyth D, Cooper JD, Collins JE et al. Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus. Diabetes 53, 3020-3023 (2004).
    • (2004) Diabetes , vol.53 , pp. 3020-3023
    • Smyth, D.1    Cooper, J.D.2    Collins, J.E.3
  • 70
    • 8744266374 scopus 로고    scopus 로고
    • The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease
    • Velaga MR, Wilson V, Jennings CE et al. The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease. J. Clin. End. Met. 89, 5862-5865 (2004).
    • (2004) J. Clin. End. Met. , vol.89 , pp. 5862-5865
    • Velaga, M.R.1    Wilson, V.2    Jennings, C.E.3
  • 71
    • 27844531635 scopus 로고    scopus 로고
    • A single-nucleotide polymorphism in the gene encoding lymphoid protein tyrosine phosphatase (PTPN22) confers susceptibility to generalised vitiligo
    • Canton I, Akhtar S, Gavalas NG et al. A single-nucleotide polymorphism in the gene encoding lymphoid protein tyrosine phosphatase (PTPN22) confers susceptibility to generalised vitiligo. Genes Immun. 6, 584-587 (2005).
    • (2005) Genes Immun , vol.6 , pp. 584-587
    • Canton, I.1    Akhtar, S.2    Gavalas, N.G.3
  • 72
    • 33846828820 scopus 로고    scopus 로고
    • Linkage proof for PTPN22, a rheumatoid arthritis susceptibility gene and a human autoimmunity gene
    • Michou L, Lasbleiz S, Rat AC et al. Linkage proof for PTPN22, a rheumatoid arthritis susceptibility gene and a human autoimmunity gene. Proc. Natl Acad. Sci. USA 104, 1649-1654 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 1649-1654
    • Michou, L.1    Lasbleiz, S.2    Rat, A.C.3
  • 73
    • 9644257170 scopus 로고    scopus 로고
    • PTPN22 and autoimmune disease
    • Siminovitch KA. PTPN22 and autoimmune disease. Nat. Genet. 36, 1248-1249 (2004).
    • (2004) Nat. Genet. , vol.36 , pp. 1248-1249
    • Siminovitch, K.A.1
  • 74
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium
    • Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447, 661-678 (2007).
    • (2007) Nature , vol.447 , pp. 661-678
  • 75
    • 33745169029 scopus 로고    scopus 로고
    • Role of PTPN22 in type 1 diabetes and other autoimmune diseases
    • Bottini N, Vang T, Cucca F, Mustelin T. Role of PTPN22 in type 1 diabetes and other autoimmune diseases. Sem. Immunol. 18, 207-213 (2006).
    • (2006) Sem. Immunol. , vol.18 , pp. 207-213
    • Bottini, N.1    Vang, T.2    Cucca, F.3    Mustelin, T.4
  • 76
    • 28444460249 scopus 로고    scopus 로고
    • Gaining insight into PTPN22 and autoimmunity
    • Gregersen PK. Gaining insight into PTPN22 and autoimmunity. Nat. Genet. 37, 1300-1302 (2005).
    • (2005) Nat. Genet. , vol.37 , pp. 1300-1302
    • Gregersen, P.K.1
  • 77
    • 28444469783 scopus 로고    scopus 로고
    • Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant
    • Vang T, Congia M, Macis MD et al. Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant. Nat. Genet. 37, 1317-1319 (2005).
    • (2005) Nat. Genet. , vol.37 , pp. 1317-1319
    • Vang, T.1    Congia, M.2    MacIs, M.D.3
  • 78
    • 65449176044 scopus 로고    scopus 로고
    • Cutting edge: The PTPN22 allelic variant associated with autoimmunity impairs B cell signaling
    • Arechiga AF, Habib T, He Y et al. Cutting edge: the PTPN22 allelic variant associated with autoimmunity impairs B cell signaling. J. Immunol. 182(6), 3343-3347 (2009).
    • (2009) J. Immunol. , vol.182 , Issue.6 , pp. 3343-3347
    • Arechiga, A.F.1    Habib, T.2    He, Y.3
  • 79
    • 33646342772 scopus 로고    scopus 로고
    • PTPN22 and invasive bacterial disease
    • Chapman SJ, Khor CC, Vannberg FO et al. PTPN22 and invasive bacterial disease. Nat. Genet. 38(5), 499-500 (2006).
    • (2006) Nat. Genet. , vol.38 , Issue.5 , pp. 499-500
    • Chapman, S.J.1    Khor, C.C.2    Vannberg, F.O.3
  • 80
    • 72849122933 scopus 로고    scopus 로고
    • From evolutionary genetics to human immunology: How selection shapes host defence genes
    • Barreiro LB, Quintana-Murci L. From evolutionary genetics to human immunology: how selection shapes host defence genes. Nat. Rev. Genet. 11(1), 17-30 (2010).
    • (2010) Nat. Rev. Genet. , vol.11 , Issue.1 , pp. 17-30
    • Barreiro, L.B.1    Quintana-Murci, L.2
  • 81
    • 42349112088 scopus 로고    scopus 로고
    • Genome-wide association studies for complex traits: Consensus, uncertainty and challenges
    • McCarthy MI, Abecasis GR, Cardon LR et al. Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat. Rev. Genet. 9(5), 356-369 (2008).
    • (2008) Nat. Rev. Genet. , vol.9 , Issue.5 , pp. 356-369
    • McCarthy, M.I.1    Abecasis, G.R.2    Cardon, L.R.3
  • 82
    • 44349132708 scopus 로고    scopus 로고
    • Common and rare variants in multifactorial susceptibility to common diseases
    • Bodmer W, Bonilla C. Common and rare variants in multifactorial susceptibility to common diseases. Nat. Genet. 40(6), 695-701 (2008).
    • (2008) Nat. Genet. , vol.40 , Issue.6 , pp. 695-701
    • Bodmer, W.1    Bonilla, C.2
  • 83
    • 34547732069 scopus 로고    scopus 로고
    • Primary immunodefciencies: A feld in its infancy
    • Casanova JL, Abel L. Primary immunodefciencies: a feld in its infancy. Science 317(5838), 617-619 (2007).
    • (2007) Science , vol.317 , Issue.5838 , pp. 617-619
    • Casanova, J.L.1    Abel, L.2


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