Role of the Zn1 and Zn2 sites in metallo-β- lactamase L1

Journal of the American Chemical Society

Volumn 130, Issue 43, 2008, Pages 14207-14216

  Hu, Zhenxin ^a   Periyannan, Gopalraj ^a,b   Bennett, Brian ^a,b   Crowder, Michael W ^a  

^a MIAMI UNIVERSITY   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTRON RESONANCE; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENZYMES; IONS; IRON COMPOUNDS; METAL IONS; METALS; NUCLEAR MAGNETIC RESONANCE; PARAMAGNETIC RESONANCE; QUANTUM THEORY; SPECTROSCOPIC ANALYSIS; ZINC COMPOUNDS;

EPR STUDIES; HETEROBIMETALLIC; KINETIC; KINETIC STUDIES; LACTAMASE; NITROCEFIN; PRODUCT COMPLEXES; REACTION INTERMEDIATES; SPECTROSCOPIC STUDIES;

ZINC;

CUPRIC ION; FERROUS ION; METAL ION; METALLO BETA LACTAMASE; NITROCEFIN; ZINC; BETA LACTAMASE; BETA LACTAMASE L1; BETA-LACTAMASE L1; CEPHALOSPORIN DERIVATIVE; COBALT; HISTIDINE; IRON; ORGANOMETALLIC COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; ELECTRON SPIN RESONANCE; ENZYME STABILITY; ENZYME SYNTHESIS; FLOW KINETICS; HYDROLYSIS; MEMBRANE STEADY POTENTIAL; NUCLEAR MAGNETIC RESONANCE; STEADY STATE; BINDING SITE; CHEMISTRY; GENETICS; KINETICS; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SITE DIRECTED MUTAGENESIS; STANDARD; TIME;

BETA-LACTAMASES; BINDING SITES; CEPHALOSPORINS; COBALT; ELECTRON SPIN RESONANCE SPECTROSCOPY; HISTIDINE; IRON; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MUTAGENESIS, SITE-DIRECTED; ORGANOMETALLIC COMPOUNDS; REFERENCE STANDARDS; TIME FACTORS; ZINC;

EID: 54849420301     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja8035916     Document Type: Article

References (54)

1. Fisher, J. F.; Meroueh, S. O.; Mobashery, S. Chem. Rev. 2005, 105, 395-424.
2. Perez, F.; Endimiani, A.; Hujer, K. M.; Bonomo, R. A. Curr. Opin. Pharmacol. 2007, 7, 459-469.
3. Walsh, T. R.; Toleman, M. A.; Poirel, L.; Nordmann, P. Clin. Microbiol. Rev. 2005, 18, 306-325.
4. Crowder, M. W.; Spencer, J.; Vila, A. J. Acc. Chem. Res. 2006, 39, 721-728.
5. Moran-Barrio, J.; Gonzalez, J. M.; Lisa, M. N.; Costello, A. L.; Dal Peraro, M.; Carloni, P.; Bennett, B.; Tierney, D. L.; Limansky, A. S.; Viale, A. M.; Vila, A. J. J. Biol. Chem. 2007, 282, 18286-18293.
6. Carfi, A.; Pares, S.; Duee, E.; Galleni, M.; Duez, C.; Frere, J. M.; Dideberg, O. EMBO J. 1995, 14, 4914-4921.
7. Fabiane, S. M.; Sohi, M. K.; Wan, T.; Payne, D. J.; Bateson, J. H.; Mitchell, T.; Sutton, B. J. Biochemistry 1998, 37, 12404-12411.
8. Davies, A. M.; Rasia, R. M.; Vila, A. J.; Sutton, B. J.; Fabiane, S. M. Biochemistry 2005, 44, 4841-4849.
9. Wommer, S.; Rival, S.; Heinz, U.; Galleni, M.; Frere, J. M.; Franceschini, N.; Amicosante, G.; Rasmussen, B.; Bauer, R.; Adolph, H. W. J. Biol. Chem. 2002, 277, 24142-24147.
10. Badarau, A.; Page, M. 1. Biochemistry 2006, 45, 11012-11020.
11. Badarau, A.; Page, M. 1. Biochemistry 2006, 45, 10654-10666.
12. Badarau, A.; Damblon, C.; Page, M. I. Biochem. J. 2007, 401, 197-203.
13. Llarrull, L. I.; Tioni, M. F.; Kowalski, J.; Bennett, B.; Vila, A. J. J. Biol. Chem. 2007, 282, 30586-30595.
14. Gonzalez, J. M.; Medrano Martin, F. J.; Costello, A. L.; Tierney, D. L.; Vila, A. J. J. Mol. Biol. 2007, 373, 1141-1156.
15. Heinz, U.; Adolph, H. W. Cell. Mol. Life Sci. 2004, 61, 2827-2839.
16. Sambrook, J.; Fritsch, E. F.; Maniatis, T. Molecular Cloning: A Laboratory Manual, 2nd ed.; Cold Spring Harbor Laboratory Press: Plainview, New York, 1989; Vol. 1.
17. Crowder, M. W.; Walsh, T. R.; Banovic, L.; Pettit, M.; Spencer, J. Antimicrob. Agents Chemother. 1998, 42, 921-926.
18. Hu, Z.; Gunasekera, T. S.; Spadafora, L.; Bennett, B.; Crowder, M. W. Biochemistry 2008, 47, 7947-7953.
19. Sharma, N. P.; Hajdin, C.; Chandrasekar, S.; Bennett, B.; Yang, K. W.; Crowder, M. W. Biochemistry 2006, 45, 10729-10738.
20. Garrity, J. D.; Bennett, B.; Crowder, M. W. Biochemistry 2005, 44, 1078-1087.
21. Carenbauer, A. L.; Garrity, J. A.; Periyannan, G.; Yates, R. B.; Crowder, M. W. BMC Biochemistry 2002, 3, 4-10.
22. Garrity, J. D.; Pauff, J. M.; Crowder, M. W. J. Biol. Chem. 2004, 279, 39663-39670.
23. Garrity, J. D.; Carenbauer, A. L.; Herron, L. R.; Crowder, M. W. J. Biol. Chem. 2004, 279, 920-927.
24. Crowder, M. W.; Yang, K. W.; Carenbauer, A. L.; Periyannan, G.; Seifert, M. A.; Rude, N. E.; Walsh, T. R. J. Biol. Inorg. Chem. 2001, 6, 91-99.
25. Garmer, D. R.; Krauss, M. J. Am. Chem. Soc. 1993, 115, 10247-10257.
26. Hu, Z.; Periyannan, G. R.; Crowder, M. W. Anal. Biochem. 2008, 378, 177-183.
27. Ullah, J. H.; Walsh, T. R.; Taylor, I. A.; Emery, D. C.; Verma, C. S.; Gamblin, S. J.; Spencer, J. J. Mol. Biol. 1998, 284, 125-136.
28. Costello, A.; Periyannan, G.; Yang, K. W.; Crowder, M. W.; Tierney, D. L. J. Biol. Inorg. Chem. 2006, 11, 351-358.
29. Outten, C. E.; O'Halloran, T. V. Science 2001, 292 (5526), 2488-2492.
30. Bennett, B.; Antholine, W. E.; D'Souza, V. M.; Chen, G. J.; Ustinyuk, L.; Holz, R. C. J. Am. Chem. Soc. 2002, 124, 13025-13034.
31. Bennett, B.; Holz, R. C. Biochemistry 1997, 36, 9837-9846.
32. Bennett, B. Curr. Top. Biophys. 2002, 26, 49-57.
33. Marasinghe, G. P. K.; Sander, I. M.; Bennett, B.; Periyannan, G.; Yang, K. W.; Makaroff, C. A.; Crowder, M. W. J. Biol. Chem. 2005, 280, 40668-40675.
34. Schilling, O.; Wenzel, N.; Naylor, M.; Vogel, A.; Crowder, M.; Makaroff, C.; Meyer-Klaucke, W. Biochemistry 2003, 42 (40), 11777-11786.
35. Bou-Abdallah, F.; Chasteen, N. D. J. Biol. Inorg. Chem. 2008, 13, 15-24.
36. Bertini, I.; Turano, P.; Vila, A. J. Chem. Rev. 1993, 93, 2833-2932.
37. Auld, D. S. Zinc Catalysis in Metalloproteases. In Metal Sites in Proteins and Models: Phosphatases, Lewis Acids, and Vanadium; Hill, H. A. O., Sadler, P. J., Thomson, A. J., Eds.; Springer-Verlag: New York, 1997; Vol. 89, pp 29-50.
38. Auld, D. S. Biometals 2001, 14, 271-313.
39. Auld, D. S. Cocatalytic zinc sites. In Handbook of Metalloproteins; Messerschmidt, A., Ed.; John Wiley & Sons: New York, 2004; Vol. 3, pp 416-431.
40. Bertini, I.; Luchinat, C. Adv. Inorg. Biochem. 1984, 6, 72-111.
41. Bertini, I.; Luchinat, C.; Scozzafava, A. Struct. Bonding (Ber.) 1982, 48, 45-92.
42. Bennett, B.; Holz, R. C. J. Am. Chem. Soc. 1997, 119, 1923-1933.
43. Nauton, L.; Kahn, R.; Garau, G.; Hernandez, J. F.; Dideberg, O. J. Mol. Biol. 2008, 375, 257-269.
44. Bertini, I.; Luchinat, C. NMR of Paramagnetic Molecules in Biological Systems; Benjamin Cummings Publishing Company: Menlo Park, CA, 1986; p 317.
45. Hegg, E. L.; Que, L. Eur. J. Biochem. 1997, 250, 625-629.
46. Wang, Z.; Fast, W.; Benkovic, S. J. Biochemistry 1999, 38, 10013-10023.
47. Kaminshaia, N. V.; Spingler, B.; Lippard, S. J. J. Am. Chem. Soc. 2000, 122, 6411-6422.
48. Kaminskaia, N. V.; Spingler, B.; Lippard, S. J. J. Am. Chem. Soc. 2001, 123, 6555-6563.
49. Wang, Z.; Benkovic, S. J. J. Biol. Chem. 1998, 273, 22402-22408.
50. Wang, Z.; Fast, W.; Benkovic, S. J. J. Am. Chem. Soc. 1998, 120, 10788.
51. Rasia, R. M.; Vila, A. J. ARKIVOC 2003, 3, 507-516.
52. Spencer, J.; Read, J.; Sessions, R. B.; Howell, S.; Blackburn, G. M.; Gamblin, S. J. J. Am. Chem. Soc. 2005, 127, 14439-14444.
53. Spencer, J.; Clark, A. R.; Walsh, T. R. J. Biol. Chem. 2001, 276, 33638-33644.
54. McMannus-Munoz, S.; Crowder, M. W. Biochemistry 1999, 38, 1547-1553.