Determination of the minimal melatonin exposure required to induce osteoblast differentiation from human mesenchymal stem cells and these effects on downstream signaling pathways

Journal of Pineal Research

Volumn 49, Issue 3, 2010, Pages 222-238

  Sethi, Shalini ^a   Radio, Nicholas M ^b   Kotlarczyk, Mary P ^a   Chen, Chien Tsun ^c,d   Wei, Yau Huei ^c,d   Jockers, Ralf ^e,f   Witt Enderby, Paula A ^a  

^a DUQUESNE UNIVERSITY   (United States)

^b Thermo Fisher Scientific   (United States)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d MACKAY MEDICAL COLLEGE   (Taiwan)

^e INSTITUT COCHIN   (France)

^f INSERM   (France)

Author keywords

beta arrestin scaffolds; MEK ERK1 2; mesenchymal stem cells; MT2 melatonin receptors; osteoblasts

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; CALCIUM; CYCLIC AMP; FORSKOLIN; MELATONIN; MELATONIN 2 RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; OSTEOCALCIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; TRANSCRIPTION FACTOR RUNX2;

ARTICLE; CELL DIFFERENTIATION; CELLULAR DISTRIBUTION; DRUG ACTIVITY; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MESENCHYMAL STEM CELL; OSTEOBLAST; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ALKALINE PHOSPHATASE; ANTIOXIDANTS; ARRESTINS; BONE MORPHOGENETIC PROTEIN 6; CELL DIFFERENTIATION; HUMANS; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MELATONIN; MESENCHYMAL STEM CELLS; OSTEOBLASTS; OSTEOGENESIS; RECEPTOR, MELATONIN, MT2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 77956325376     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2010.00784.x     Document Type: Article

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