메뉴 건너뛰기




Volumn 45, Issue 3, 2008, Pages 229-234

Novel bromomelatonin derivatives as potentially effective drugs to treat bone diseases

Author keywords

Bone diseases; Bromomelatonin derivatives; Low calcium diet rats; Osteoblasts; Osteoclasts; Ovariectomized rats; Scales

Indexed keywords

1 BENZYL 2,4,6 TRIBOMOMELATONIN; BENZYL TRIBOMOMELATONIN; BROMOMELATONIN DERIVATIVE; MELATONIN DERIVATIVE; TRIBOMOMELATONIN DERIVATIVE; UNCLASSIFIED DRUG;

EID: 51649105998     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2008.00623.x     Document Type: Short Survey
Times cited : (78)

References (55)
  • 1
    • 0025915557 scopus 로고
    • Melatonin: The chemical expression of darkness
    • Reiter RJ. Melatonin: the chemical expression of darkness. Mol Cell Endocrinol 1991 79: C153 C158.
    • (1991) Mol Cell Endocrinol , vol.79
    • Reiter, R.J.1
  • 2
    • 0027210003 scopus 로고
    • The melatonin rhythm: Both a clock and a calendar
    • Reiter RJ. The melatonin rhythm: both a clock and a calendar. Experientia 1993 49: 654 664.
    • (1993) Experientia , vol.49 , pp. 654-664
    • Reiter, R.J.1
  • 3
    • 0019405864 scopus 로고
    • Age-associated reduction in nocturnal pineal melatonin levels in female rats
    • Reiter RJ, Craft CM, Johnson JE Jr et al. Age-associated reduction in nocturnal pineal melatonin levels in female rats. Endocrinology 1981 109: 1295 1297.
    • (1981) Endocrinology , vol.109 , pp. 1295-1297
    • Reiter, R.J.1    Craft, C.M.2    Johnson Jr., J.E.3
  • 4
    • 0022973346 scopus 로고
    • Human melatonin production decreases with age
    • Sack RL, Lewy AJ, Erb DL et al. Human melatonin production decreases with age. J Pineal Res 1986 3: 379 388.
    • (1986) J Pineal Res , vol.3 , pp. 379-388
    • Sack, R.L.1    Lewy, A.J.2    Erb, D.L.3
  • 5
    • 0026830761 scopus 로고
    • The ageing pineal gland and its physiological consequences
    • Reiter RJ. The ageing pineal gland and its physiological consequences. BioEssays 1992 14: 169 175.
    • (1992) BioEssays , vol.14 , pp. 169-175
    • Reiter, R.J.1
  • 6
    • 0019788322 scopus 로고
    • Phototherapy-induced hypocalcemia in newborn rats: Prevention by melatonin
    • Hakanson DO, Bergstrom WH. Phototherapy-induced hypocalcemia in newborn rats: prevention by melatonin. Science 1981 214: 807 809.
    • (1981) Science , vol.214 , pp. 807-809
    • Hakanson, D.O.1    Bergstrom, W.H.2
  • 7
    • 0036830138 scopus 로고    scopus 로고
    • Melatonin suppresses osteoclastic and osteoblastic activities in the scales of goldfish
    • Suzuki N, Hattori A. Melatonin suppresses osteoclastic and osteoblastic activities in the scales of goldfish. J Pineal Res 2002 33: 253 258.
    • (2002) J Pineal Res , vol.33 , pp. 253-258
    • Suzuki, N.1    Hattori, A.2
  • 8
    • 0033994210 scopus 로고    scopus 로고
    • Suppression of osteoclastic activities by calcitonin in the scales of goldfish (freshwater teleost) and nibbler fish (seawater teleost)
    • Suzuki N, Suzuki T, Kurokawa T. Suppression of osteoclastic activities by calcitonin in the scales of goldfish (freshwater teleost) and nibbler fish (seawater teleost). Peptides 2000 21: 115 124.
    • (2000) Peptides , vol.21 , pp. 115-124
    • Suzuki, N.1    Suzuki, T.2    Kurokawa, T.3
  • 9
    • 40849131148 scopus 로고    scopus 로고
    • Novel bromomelatonin derivatives suppress osteoclastic activity and increase osteoblastic activity: Implications for the treatment of bone diseases
    • Suzuki N, Somei M, Kitamura K et al. Novel bromomelatonin derivatives suppress osteoclastic activity and increase osteoblastic activity: implications for the treatment of bone diseases. J Pineal Res 2008 44: 326 334.
    • (2008) J Pineal Res , vol.44 , pp. 326-334
    • Suzuki, N.1    Somei, M.2    Kitamura, K.3
  • 10
    • 0014645812 scopus 로고
    • Endocrine regulation of blood calcium level. II. Relationship between the pineal body and the parathyroid glands
    • Kiss J, Banhegyi D, Csaba G. Endocrine regulation of blood calcium level. II. Relationship between the pineal body and the parathyroid glands. Acta Med Acad Sci Hung 1969 26: 363 370.
    • (1969) Acta Med Acad Sci Hung , vol.26 , pp. 363-370
    • Kiss, J.1    Banhegyi, D.2    Csaba, G.3
  • 11
    • 0016152379 scopus 로고
    • The effect of pinealectomy on the parafollicular cells of the rat thyroid gland
    • Csaba G, Barath P. The effect of pinealectomy on the parafollicular cells of the rat thyroid gland. Acta Anat (Basel) 1974 88: 137 146.
    • (1974) Acta Anat (Basel) , vol.88 , pp. 137-146
    • Csaba, G.1    Barath, P.2
  • 12
    • 0016663618 scopus 로고
    • Morphological changes of thymus and the thyroid gland after postnatal extirpation of pineal body
    • Csaba G, Barath P. Morphological changes of thymus and the thyroid gland after postnatal extirpation of pineal body. Endcrinol Exp 1975 9: 59 67.
    • (1975) Endcrinol Exp , vol.9 , pp. 59-67
    • Csaba, G.1    Barath, P.2
  • 13
    • 0026069187 scopus 로고
    • Effects of melatonin on the ultrastructure of the golden hamster parathyroid gland
    • Chen H, Shoumura S, Emura S et al. Effects of melatonin on the ultrastructure of the golden hamster parathyroid gland. Histol Histopath 1991 6: 1 7.
    • (1991) Histol Histopath , vol.6 , pp. 1-7
    • Chen, H.1    Shoumura, S.2    Emura, S.3
  • 14
    • 0026474714 scopus 로고
    • An in vitro study on the effects of melatonin on the ultrastructure of the hamster parathyroid gland
    • Shoumura S, Chen H, Emura S et al. An in vitro study on the effects of melatonin on the ultrastructure of the hamster parathyroid gland. Histol Histopath 1992 7: 715 718.
    • (1992) Histol Histopath , vol.7 , pp. 715-718
    • Shoumura, S.1    Chen, H.2    Emura, S.3
  • 15
    • 0017709090 scopus 로고
    • The effect of melatonin and corpus pineal extract on serum electrolytes in the rat
    • Csaba G, Bokay J. The effect of melatonin and corpus pineal extract on serum electrolytes in the rat. Acta Biol Acad Sci Hung 1977 28: 143 144.
    • (1977) Acta Biol Acad Sci Hung , vol.28 , pp. 143-144
    • Csaba, G.1    Bokay, J.2
  • 16
    • 0027261283 scopus 로고
    • An experimental study in chickens for the pathogenesis of idiopathic scoliosis
    • Machida M, Dubousset J, Imamura Y et al. An experimental study in chickens for the pathogenesis of idiopathic scoliosis. Spine 1993 18: 1609 1615.
    • (1993) Spine , vol.18 , pp. 1609-1615
    • MacHida, M.1    Dubousset, J.2    Imamura, Y.3
  • 17
    • 0033015041 scopus 로고    scopus 로고
    • The effects of melatonin therapy on the development of scoliosis after pinealectomy in the chicken
    • Bagnall K, Raso VJ, Moreau M et al. The effects of melatonin therapy on the development of scoliosis after pinealectomy in the chicken. J Bone Joint Surg Am 1999 81: 191 199.
    • (1999) J Bone Joint Surg Am , vol.81 , pp. 191-199
    • Bagnall, K.1    Raso, V.J.2    Moreau, M.3
  • 18
    • 0033994607 scopus 로고    scopus 로고
    • Adolescent idiopathic scoliosis. Is low melatonin a cause?
    • Sadat-Ali M, Al-Habdan I, Al-Othman A. Adolescent idiopathic scoliosis. Is low melatonin a cause? Joint Bone Spine 2000 67: 62 64.
    • (2000) Joint Bone Spine , vol.67 , pp. 62-64
    • Sadat-Ali, M.1    Al-Habdan, I.2    Al-Othman, A.3
  • 19
    • 18044404578 scopus 로고    scopus 로고
    • Pathologic mechanism of experimental scoliosis in pinealectomized chickens
    • Machida M, Duboussent J, Satoh T et al. Pathologic mechanism of experimental scoliosis in pinealectomized chickens. Spine 2001 26: E385 E391.
    • (2001) Spine , vol.26
    • MacHida, M.1    Duboussent, J.2    Satoh, T.3
  • 20
    • 27744539112 scopus 로고    scopus 로고
    • Morphological, stereological and radiological changes in pinealectomized chicken cervical vertebrae
    • Turgut M, Kaplan S, Turgut AT et al. Morphological, stereological and radiological changes in pinealectomized chicken cervical vertebrae. J Pineal Res 2005 39: 392 399.
    • (2005) J Pineal Res , vol.39 , pp. 392-399
    • Turgut, M.1    Kaplan, S.2    Turgut, A.T.3
  • 21
    • 0033215118 scopus 로고    scopus 로고
    • Pathogenesis of idiopathic scoliosis: Experimental study in rats
    • Machida M, Murai I, Miyashita Y et al. Pathogenesis of idiopathic scoliosis: experimental study in rats. Spine 1999 24: 1985 1989.
    • (1999) Spine , vol.24 , pp. 1985-1989
    • MacHida, M.1    Murai, I.2    Miyashita, Y.3
  • 22
    • 1342280383 scopus 로고    scopus 로고
    • Pinealectomy induces malformation of the spine and reduces the mechanical strength of the vertebrae in Atlantic salmon, Salmo salar
    • Fjelldal PG, Grotmol S, Kryvi H et al. Pinealectomy induces malformation of the spine and reduces the mechanical strength of the vertebrae in Atlantic salmon, Salmo salar. J Pineal Res 2004 36: 132 139.
    • (2004) J Pineal Res , vol.36 , pp. 132-139
    • Fjelldal, P.G.1    Grotmol, S.2    Kryvi, H.3
  • 23
    • 0242404593 scopus 로고    scopus 로고
    • The effects of pineal gland transplantation on the production of spinal deformity and serum melatonin level following pinealectomy in the chicken
    • Turgut M, Yenisey C, Uysal A et al. The effects of pineal gland transplantation on the production of spinal deformity and serum melatonin level following pinealectomy in the chicken. Eur Spine J 2003 12: 487 494.
    • (2003) Eur Spine J , vol.12 , pp. 487-494
    • Turgut, M.1    Yenisey, C.2    Uysal, A.3
  • 24
    • 0032829442 scopus 로고    scopus 로고
    • Identification of highly elevated levels of melatonin in bone marrow: Its origin and significance
    • Tan DX, Manchester LC, Reiter RJ et al. Identification of highly elevated levels of melatonin in bone marrow: its origin and significance. Biochim Biophys Acta 1999 1472: 206 214.
    • (1999) Biochim Biophys Acta , vol.1472 , pp. 206-214
    • Tan, D.X.1    Manchester, L.C.2    Reiter, R.J.3
  • 25
    • 0034013426 scopus 로고    scopus 로고
    • Evidence for melatonin synthesis in mouse and human bone marrow cells
    • Conti A, Conconi S, Hertens E et al. Evidence for melatonin synthesis in mouse and human bone marrow cells. J Pineal Res 2000 28: 193 202.
    • (2000) J Pineal Res , vol.28 , pp. 193-202
    • Conti, A.1    Conconi, S.2    Hertens, E.3
  • 26
    • 0033618379 scopus 로고    scopus 로고
    • Melatonin promotes osteoblast differentiation and bone formation.
    • Roth JA, Kim B-G, Lin W-L, Cho M-I. Melatonin promotes osteoblast differentiation and bone formation. J Biol Chem 1999 274: 22041 22047.
    • (1999) J Biol Chem , vol.274 , pp. 22041-22047
    • Roth, J.A.1    Kim, B.-G.2    Lin, W.-L.3    Cho, M.-I.4
  • 27
    • 0032873439 scopus 로고    scopus 로고
    • Melatonin stimulates proliferation and type I collagen synthesis in human bone cells in vitro
    • Nakade O, Koyama H, Ariji H et al. Melatonin stimulates proliferation and type I collagen synthesis in human bone cells in vitro. J Pineal Res 1999 27: 106 110.
    • (1999) J Pineal Res , vol.27 , pp. 106-110
    • Nakade, O.1    Koyama, H.2    Ariji, H.3
  • 28
    • 33847635533 scopus 로고    scopus 로고
    • Melatonin at pharmacological doses enhances human osteoblastic differentiation in vitro and promotes mouse cortical bone formation in vivo
    • Satomura K, Tobiume S, Tokuyama R et al. Melatonin at pharmacological doses enhances human osteoblastic differentiation in vitro and promotes mouse cortical bone formation in vivo. J Pineal Res 2007 42: 231 239.
    • (2007) J Pineal Res , vol.42 , pp. 231-239
    • Satomura, K.1    Tobiume, S.2    Tokuyama, R.3
  • 29
    • 0035034468 scopus 로고    scopus 로고
    • Assessment of the relationship between dynamic pattern of nighttime levels of melatonin and chosen biochemical markers of bone metabolism in a rat model of postmenopausal osteoporosis
    • Ostrowska Z, Kos-Kudla B, Swietochowska E et al. Assessment of the relationship between dynamic pattern of nighttime levels of melatonin and chosen biochemical markers of bone metabolism in a rat model of postmenopausal osteoporosis. Neuro Endocrinol Lett 2001 22: 129 136.
    • (2001) Neuro Endocrinol Lett , vol.22 , pp. 129-136
    • Ostrowska, Z.1    Kos-Kudla, B.2    Swietochowska, E.3
  • 30
    • 0035030275 scopus 로고    scopus 로고
    • Assessment of the relationship between circadian variations of salivary melatonin levels and type I collagen metabolism in postmenopausal obese women
    • Ostrowska Z, Kos-Kudla B, Marek B et al. Assessment of the relationship between circadian variations of salivary melatonin levels and type I collagen metabolism in postmenopausal obese women. Neuro Endocrinol Lett 2001 22: 121 127.
    • (2001) Neuro Endocrinol Lett , vol.22 , pp. 121-127
    • Ostrowska, Z.1    Kos-Kudla, B.2    Marek, B.3
  • 31
    • 0035931019 scopus 로고    scopus 로고
    • Effect of melatonin on bone metabolism in ovariectomized rats
    • Ladizesky MG, Cutrera RA, Boggio V et al. Effect of melatonin on bone metabolism in ovariectomized rats. Life Sci 2001 70: 557 565.
    • (2001) Life Sci , vol.70 , pp. 557-565
    • Ladizesky, M.G.1    Cutrera, R.A.2    Boggio, V.3
  • 32
    • 0037371271 scopus 로고    scopus 로고
    • Melatonin increases oestradiol-induced bone formation in ovariectomized rats
    • Ladizesky MG, Boggio V, Albornoz LE et al. Melatonin increases oestradiol-induced bone formation in ovariectomized rats. J Pineal Res 2003 34: 143 151.
    • (2003) J Pineal Res , vol.34 , pp. 143-151
    • Ladizesky, M.G.1    Boggio, V.2    Albornoz, L.E.3
  • 33
    • 0035991254 scopus 로고    scopus 로고
    • Melatonin at pharmacologic doses increases bone mass by suppressing resorption through down-regulation of the RANKL-mediated osteoclast formation and activation
    • Koyama H, Nakade O, Takada Y et al. Melatonin at pharmacologic doses increases bone mass by suppressing resorption through down-regulation of the RANKL-mediated osteoclast formation and activation. J Bone Miner Res 2002 17: 1219 1229.
    • (2002) J Bone Miner Res , vol.17 , pp. 1219-1229
    • Koyama, H.1    Nakade, O.2    Takada, Y.3
  • 34
    • 35348933859 scopus 로고    scopus 로고
    • Constructive effect exogenous melatonin against osteoporosis after ovariectomy in rats
    • Uslu S, Uysal A, Öktem G et al. Constructive effect exogenous melatonin against osteoporosis after ovariectomy in rats. Anal Quant Cytol Histol 2007 29: 317 325.
    • (2007) Anal Quant Cytol Histol , vol.29 , pp. 317-325
    • Uslu, S.1    Uysal, A.2    Öktem, G.3
  • 35
    • 0001475252 scopus 로고
    • Studies on the structure and growth of the scales in the goldfish
    • Yamada J. Studies on the structure and growth of the scales in the goldfish. Mem Fac Fish Hokkaido Univ 1961 9: 181 226.
    • (1961) Mem Fac Fish Hokkaido Univ , vol.9 , pp. 181-226
    • Yamada, J.1
  • 36
    • 85004390325 scopus 로고
    • A fine structural aspect of the development of scales in the chum salmon fry
    • Yamada J. A fine structural aspect of the development of scales in the chum salmon fry. Bull Jap Soc Sci Fish 1971 37: 18 29.
    • (1971) Bull Jap Soc Sci Fish , vol.37 , pp. 18-29
    • Yamada, J.1
  • 38
    • 15544375639 scopus 로고    scopus 로고
    • Osteoblastic activity and estrogenic response in the regenerating scale of goldfish, a good model of osteogenesis
    • Yoshikubo H, Suzuki N, Takemura K et al. Osteoblastic activity and estrogenic response in the regenerating scale of goldfish, a good model of osteogenesis. Life Sci 2005 76: 2699 2709.
    • (2005) Life Sci , vol.76 , pp. 2699-2709
    • Yoshikubo, H.1    Suzuki, N.2    Takemura, K.3
  • 39
    • 0026806878 scopus 로고
    • Organization and characterization of fibrillar collagens in fish scales in situ and in vitro
    • Zylberberg L, Bonaventure J, Cohen-Solal L et al. Organization and characterization of fibrillar collagens in fish scales in situ and in vitro. J Cell Sci 1992 103: 273 285.
    • (1992) J Cell Sci , vol.103 , pp. 273-285
    • Zylberberg, L.1    Bonaventure, J.2    Cohen-Solal, L.3
  • 40
    • 0026656754 scopus 로고
    • Discovery of bone γ-carboxyglutamic acid protein in mineralized scales
    • Nishimoto SK, Araki N, Robinson FD, Waite JH. Discovery of bone γ-carboxyglutamic acid protein in mineralized scales. J Biol Chem 1992 267: 11600 11605.
    • (1992) J Biol Chem , vol.267 , pp. 11600-11605
    • Nishimoto, S.K.1    Araki, N.2    Robinson, F.D.3    Waite, J.H.4
  • 41
    • 0032933279 scopus 로고    scopus 로고
    • Cloning of a fragment of the osteonectin gene from goldfish, Carassius auratus: Its expression and potential regulation by estrogen
    • Lehane DB, Mckie N, Russell RGG, Henderson IW. Cloning of a fragment of the osteonectin gene from goldfish, Carassius auratus: its expression and potential regulation by estrogen. Gen Comp Endocrinol 1999 114: 80 87.
    • (1999) Gen Comp Endocrinol , vol.114 , pp. 80-87
    • Lehane, D.B.1    McKie, N.2    Russell, R.G.G.3    Henderson, I.W.4
  • 42
    • 0018574414 scopus 로고
    • Studies on fish scale formation and resorption. III. Fine structure and calcification of the fibrillary plates of the scales in Carassius auratus (Cypriniformes: Cyprinidae)
    • Onozato H, Watabe N. Studies on fish scale formation and resorption. III. Fine structure and calcification of the fibrillary plates of the scales in Carassius auratus (Cypriniformes: Cyprinidae). Cell Tissue Res 1979 201: 409 422.
    • (1979) Cell Tissue Res , vol.201 , pp. 409-422
    • Onozato, H.1    Watabe, N.2
  • 43
    • 34548384725 scopus 로고    scopus 로고
    • Two osteoclastic markers expressed in multinucleate osteoclasts of goldfish scales
    • Azuma K, Kobayashi M, Nakamura M et al. Two osteoclastic markers expressed in multinucleate osteoclasts of goldfish scales. Biochem Biophys Res Commun 2007 362: 594 600.
    • (2007) Biochem Biophys Res Commun , vol.362 , pp. 594-600
    • Azuma, K.1    Kobayashi, M.2    Nakamura, M.3
  • 44
    • 0001323684 scopus 로고
    • Studies on the metabolism of calcium and strontium in freshwater fish. I. Relative contribution of direct and intestinal absorption
    • Berg A. Studies on the metabolism of calcium and strontium in freshwater fish. I. Relative contribution of direct and intestinal absorption. Mem Ist Ital Idrobiol 1968 23: 161 196.
    • (1968) Mem Ist Ital Idrobiol , vol.23 , pp. 161-196
    • Berg, A.1
  • 45
    • 0017364187 scopus 로고
    • Studies on fish scale formation and resorption II: Effect of estradiol on calcium homeostasis and skeletal tissue resorption in the goldfish, Carassius auratus, and the killifish, Fundulus heteroclitus
    • Mugiya Y, Watabe N. Studies on fish scale formation and resorption II: effect of estradiol on calcium homeostasis and skeletal tissue resorption in the goldfish, Carassius auratus, and the killifish, Fundulus heteroclitus. Comp Biochem Physiol 1977 57A: 197 202.
    • (1977) Comp Biochem Physiol , vol.57 , pp. 197-202
    • Mugiya, Y.1    Watabe, N.2
  • 46
    • 0023784985 scopus 로고
    • Cellular biology and biochemical mechanism of bone resorption
    • Vaes G. Cellular biology and biochemical mechanism of bone resorption. Clin Ortop 1988 231: 239 271.
    • (1988) Clin Ortop , vol.231 , pp. 239-271
    • Vaes, G.1
  • 47
    • 0032030521 scopus 로고    scopus 로고
    • Alkaline phosphatase levels and osteoprogenitor cell numbers suggest bone formation may contribute to peak bone density differences between two inbred strains of mice
    • Dimai HP, Linkhart TA, Linkhart SG et al. Alkaline phosphatase levels and osteoprogenitor cell numbers suggest bone formation may contribute to peak bone density differences between two inbred strains of mice. Bone 1998 22: 211 216.
    • (1998) Bone , vol.22 , pp. 211-216
    • Dimai, H.P.1    Linkhart, T.A.2    Linkhart, S.G.3
  • 48
    • 0242443191 scopus 로고    scopus 로고
    • Influence of lighting conditions on daily rhythm of bone metabolism in rats and possible involvement of melatonin and other hormones in this process
    • Ostrowska Z, Kos-Kudla B, Marek B, Kajdaniuk D. Influence of lighting conditions on daily rhythm of bone metabolism in rats and possible involvement of melatonin and other hormones in this process. Endocr Regul 2003 37: 163 174.
    • (2003) Endocr Regul , vol.37 , pp. 163-174
    • Ostrowska, Z.1    Kos-Kudla, B.2    Marek, B.3    Kajdaniuk, D.4
  • 49
    • 0033304730 scopus 로고    scopus 로고
    • Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families
    • Suda T, Takahashi N, Udagawa N et al. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev 1999 20: 345 357.
    • (1999) Endocr Rev , vol.20 , pp. 345-357
    • Suda, T.1    Takahashi, N.2    Udagawa, N.3
  • 50
    • 0034455103 scopus 로고    scopus 로고
    • Birth and death of bone cells: Basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis
    • Manolagas SC. Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocr Rev 2000 21: 115 137.
    • (2000) Endocr Rev , vol.21 , pp. 115-137
    • Manolagas, S.C.1
  • 51
    • 0034284970 scopus 로고    scopus 로고
    • Bone resorption by osteoclasts
    • Teitelbaum SL. Bone resorption by osteoclasts. Science 2000 289: 1504 1508.
    • (2000) Science , vol.289 , pp. 1504-1508
    • Teitelbaum, S.L.1
  • 52
    • 0022003590 scopus 로고
    • Circadian variations in the inhibition of dopamine release from adult and newborn rat hypothalamus by melatonin
    • Zisapel N, Egozi Y, Laudon M. Circadian variations in the inhibition of dopamine release from adult and newborn rat hypothalamus by melatonin. Neuroendocrinology 1985 40: 102 108.
    • (1985) Neuroendocrinology , vol.40 , pp. 102-108
    • Zisapel, N.1    Egozi, Y.2    Laudon, M.3
  • 53
    • 0030882965 scopus 로고    scopus 로고
    • Effect of melatonin and metabolites on copper-mediated oxidation of low density lipoprotein
    • Seeger H, Mueck AO, Lippert TH. Effect of melatonin and metabolites on copper-mediated oxidation of low density lipoprotein. Br J Clin Pharmacol 1997 44: 283 284.
    • (1997) Br J Clin Pharmacol , vol.44 , pp. 283-284
    • Seeger, H.1    Mueck, A.O.2    Lippert, T.H.3
  • 54
    • 9644275747 scopus 로고    scopus 로고
    • Recovery of experimental Parkinson's disease with the melatonin analogues ML-23 and S-20928 in a chronic, bilateral 6-OHDA model: A new mechanism involving antagonism of the melatonin receptor
    • Willis GL, Robertson AD. Recovery of experimental Parkinson's disease with the melatonin analogues ML-23 and S-20928 in a chronic, bilateral 6-OHDA model: a new mechanism involving antagonism of the melatonin receptor. Pharmacol Biochem Behav 2004 79: 413 429.
    • (2004) Pharmacol Biochem Behav , vol.79 , pp. 413-429
    • Willis, G.L.1    Robertson, A.D.2
  • 55
    • 36048931674 scopus 로고    scopus 로고
    • Oral bisphosphonate-induced osteonecrosis: Risk factors, prediction of risk using serum CTX testing, prevention, and treatment
    • Marx RE, Cillo JE Jr, Ulloa JJ. Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment. J Oral Maxillofac Surg 2007 65: 2397 2410.
    • (2007) J Oral Maxillofac Surg , vol.65 , pp. 2397-2410
    • Marx, R.E.1    Cillo Jr., J.E.2    Ulloa, J.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.