메뉴 건너뛰기




Volumn 185, Issue 1, 2010, Pages 560-568

CD8+ T cells specific for immunodominant trans-sialidase epitopes contribute to control of trypanosoma cruzi infection but are not required for resistance

Author keywords

[No Author keywords available]

Indexed keywords

ALANYLASPARAGINYLTYROSYLLYSYLPHENYLALANYLTHREONYLLEUCYLVALINE; EPITOPE; ISOLEUCYLTYROSYLASPARAGINYLVALYLGLYCYLGLUTAMINYLVALYLSERYLISOLEUCINE; SIALIDASE; UNCLASSIFIED DRUG; VALYLASPARAGINYLTYROSYLASPARTYLPHENYLALANYLTHREONYLLEUCYLVALINE; GLYCOPROTEIN; PEPTIDE FRAGMENT; TRANS SIALIDASE; TRANS-SIALIDASE;

EID: 77956209421     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1000432     Document Type: Article
Times cited : (59)

References (67)
  • 1
    • 0041468870 scopus 로고    scopus 로고
    • CD8 T cell responses to infectious pathogens
    • Wong, P., and E. G. Pamer. 2003. CD8 T cell responses to infectious pathogens. Annu. Rev. Immunol. 21: 29-70.
    • (2003) Annu. Rev. Immunol. , vol.21 , pp. 29-70
    • Wong, P.1    Pamer, E.G.2
  • 2
    • 0034097041 scopus 로고    scopus 로고
    • CD8+ T cell effector mechanisms in resistance to infection
    • Harty, J. T., A. R. Tvinnereim, and D. W. White. 2000. CD8+ T cell effector mechanisms in resistance to infection. Annu. Rev. Immunol. 18: 275-308.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 275-308
    • Harty, J.T.1    Tvinnereim, A.R.2    White, D.W.3
  • 3
    • 0033046472 scopus 로고    scopus 로고
    • Immunodominance in major histo-compatibility complex class I-restricted T lymphocyte responses
    • Yewdell, J. W., and J. R. Bennink. 1999. Immunodominance in major histo-compatibility complex class I-restricted T lymphocyte responses. Annu. Rev. Immunol. 17: 51-88.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 51-88
    • Yewdell, J.W.1    Bennink, J.R.2
  • 4
    • 5044222206 scopus 로고    scopus 로고
    • Immune responses to Listeria monocytogenes
    • Pamer, E. G. 2004. Immune responses to Listeria monocytogenes. Nat. Rev. Immunol. 4: 812-823.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 812-823
    • Pamer, E.G.1
  • 5
    • 33749528390 scopus 로고    scopus 로고
    • Confronting complexity: Real-world immunodominance in antiviral CD8+ T cell responses
    • Yewdell, J. W. 2006. Confronting complexity: real-world immunodominance in antiviral CD8+ T cell responses. Immunity 25: 533-543.
    • (2006) Immunity , vol.25 , pp. 533-543
    • Yewdell, J.W.1
  • 6
    • 47849095938 scopus 로고    scopus 로고
    • Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum
    • Blanchard, N., F. Gonzalez, M. Schaeffer, N. T. Joncker, T. Cheng, A. J. Shastri, E. A. Robey, and N. Shastri. 2008. Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum. Nat. Immunol. 9: 937-944.
    • (2008) Nat. Immunol. , vol.9 , pp. 937-944
    • Blanchard, N.1    Gonzalez, F.2    Schaeffer, M.3    Joncker, N.T.4    Cheng, T.5    Shastri, A.J.6    Robey, E.A.7    Shastri, N.8
  • 14
    • 34548050436 scopus 로고    scopus 로고
    • CD8 T cell dysfunction during chronic viral infection
    • Shin, H., and E. J. Wherry. 2007. CD8 T cell dysfunction during chronic viral infection. Curr. Opin. Immunol. 19: 408-415.
    • (2007) Curr. Opin. Immunol. , vol.19 , pp. 408-415
    • Shin, H.1    Wherry, E.J.2
  • 15
    • 12444258695 scopus 로고    scopus 로고
    • Antigen-specific T cells maintain an effector memory phenotype during persistent Trypanosoma cruzi infection
    • Martin, D. L., and R. L. Tarleton. 2005. Antigen-specific T cells maintain an effector memory phenotype during persistent Trypanosoma cruzi infection. J. Immunol. 174: 1594-1601.
    • (2005) J. Immunol. , vol.174 , pp. 1594-1601
    • Martin, D.L.1    Tarleton, R.L.2
  • 16
    • 43249116465 scopus 로고    scopus 로고
    • Drug-induced cure drives conversion to a stable and protective CD8+ T central memory response in chronic Chagas disease
    • Bustamante, J. M., L. M. Bixby, and R. L. Tarleton. 2008. Drug-induced cure drives conversion to a stable and protective CD8+ T central memory response in chronic Chagas disease. Nat. Med. 14: 542-550.
    • (2008) Nat. Med. , vol.14 , pp. 542-550
    • Bustamante, J.M.1    Bixby, L.M.2    Tarleton, R.L.3
  • 17
    • 38449108012 scopus 로고    scopus 로고
    • Trans-sialidase recombinant protein mixed with CpG motif-containing oligodeoxynucleotide induces protective mucosal and systemic trypanosoma cruzi immunity involving CD8+ CTL and B cell-mediated cross-priming
    • Hoft, D. F., C. S. Eickhoff, O. K. Giddings, J. R. Vasconcelos, and M. M. Rodrigues. 2007. Trans-sialidase recombinant protein mixed with CpG motif-containing oligodeoxynucleotide induces protective mucosal and systemic trypanosoma cruzi immunity involving CD8+ CTL and B cell-mediated cross-priming. J. Immunol. 179: 6889-6900.
    • (2007) J. Immunol. , vol.179 , pp. 6889-6900
    • Hoft, D.F.1    Eickhoff, C.S.2    Giddings, O.K.3    Vasconcelos, J.R.4    Rodrigues, M.M.5
  • 18
    • 53149087102 scopus 로고    scopus 로고
    • Stable CD8+ T cell memory during persistent Trypanosoma cruzi infection
    • Bixby, L. M., and R. L. Tarleton. 2008. Stable CD8+ T cell memory during persistent Trypanosoma cruzi infection. J. Immunol. 181: 2644-2650.
    • (2008) J. Immunol. , vol.181 , pp. 2644-2650
    • Bixby, L.M.1    Tarleton, R.L.2
  • 19
    • 0034234658 scopus 로고    scopus 로고
    • Functional diversity in the trans-sialidase and mucin families in Trypanosoma cruzi
    • Frasch, A. C. 2000. Functional diversity in the trans-sialidase and mucin families in Trypanosoma cruzi. Parasitol. Today 16: 282-286.
    • (2000) Parasitol. Today , vol.16 , pp. 282-286
    • Frasch, A.C.1
  • 21
    • 23944437463 scopus 로고    scopus 로고
    • CD8+-T-cell-dependent control of Trypanosoma cruzi infection in a highly susceptible mouse strain after immunization with recombinant proteins based on amastigote surface protein 2
    • Araújo, A. F., B. C. de Alencar, J. R. Vasconcelos, M. I. Hiyane, C. R. Marinho, M. L. Penido, S. B. Boscardin, D. F. Hoft, R. T. Gazzinelli, and M. M. Rodrigues. 2005. CD8+-T-cell-dependent control of Trypanosoma cruzi infection in a highly susceptible mouse strain after immunization with recombinant proteins based on amastigote surface protein 2. Infect. Immun. 73: 6017-6025.
    • (2005) Infect. Immun. , vol.73 , pp. 6017-6025
    • Araújo, A.F.1    De Alencar, B.C.2    Vasconcelos, J.R.3    Hiyane, M.I.4    Marinho, C.R.5    Penido, M.L.6    Boscardin, S.B.7    Hoft, D.F.8    Gazzinelli, R.T.9    Rodrigues, M.M.10
  • 23
    • 65549136160 scopus 로고    scopus 로고
    • Immunodominance: A new hypothesis to explain parasite escape and host/parasite equilibrium leading to the chronic phase of Chagas' disease?
    • Rodrigues, M. M., B. C. Alencar, C. Claser, and F. Tzelepis. 2009. Immunodominance: a new hypothesis to explain parasite escape and host/parasite equilibrium leading to the chronic phase of Chagas' disease? Braz. J. Med. Biol. Res. 42: 220-223.
    • (2009) Braz. J. Med. Biol. Res. , vol.42 , pp. 220-223
    • Rodrigues, M.M.1    Alencar, B.C.2    Claser, C.3    Tzelepis, F.4
  • 24
    • 4844220220 scopus 로고    scopus 로고
    • Generation, specificity, and function of CD8+ T cells in Trypanosoma cruzi infection
    • Martin, D., and R. Tarleton. 2004. Generation, specificity, and function of CD8+ T cells in Trypanosoma cruzi infection. Immunol. Rev. 201: 304-317.
    • (2004) Immunol. Rev. , vol.201 , pp. 304-317
    • Martin, D.1    Tarleton, R.2
  • 25
    • 0033563014 scopus 로고    scopus 로고
    • The surface protein superfamily of Trypanosoma cruzi stimulates a polarized Th1 response that becomes anergic
    • Millar, A. E., M. Wleklinski-Lee, and S. J. Kahn. 1999. The surface protein superfamily of Trypanosoma cruzi stimulates a polarized Th1 response that becomes anergic. J. Immunol. 162: 6092-6099.
    • (1999) J. Immunol. , vol.162 , pp. 6092-6099
    • Millar, A.E.1    Wleklinski-Lee, M.2    Kahn, S.J.3
  • 26
    • 34548021449 scopus 로고    scopus 로고
    • Immune system recognition of Trypanosoma cruzi
    • Tarleton, R. L. 2007. Immune system recognition of Trypanosoma cruzi. Curr. Opin. Immunol. 19: 430-434.
    • (2007) Curr. Opin. Immunol. , vol.19 , pp. 430-434
    • Tarleton, R.L.1
  • 27
    • 0038512547 scopus 로고    scopus 로고
    • Rapid quantitation of Trypanosoma cruzi in host tissue by real-time PCR
    • Cummings, K. L., and R. L. Tarleton. 2003. Rapid quantitation of Trypanosoma cruzi in host tissue by real-time PCR. Mol. Biochem. Parasitol. 129: 53-59.
    • (2003) Mol. Biochem. Parasitol. , vol.129 , pp. 53-59
    • Cummings, K.L.1    Tarleton, R.L.2
  • 28
    • 0030982709 scopus 로고    scopus 로고
    • Peptide antigen treatment of naive and virus-immune mice: Antigen-specific tolerance versus immunopathology
    • DOI 10.1016/S1074-7613(00)80340-4
    • Aichele, P., K. Brduscha-Riem, S. Oehen, B. Odermatt, R. M. Zinkernagel, H. Hengartner, and H. Pircher. 1997. Peptide antigen treatment of naive and virus-immune mice: antigen-specific tolerance versus immunopathology. Immunity 6: 519-529. (Pubitemid 27239343)
    • (1997) Immunity , vol.6 , Issue.5 , pp. 519-529
    • Aichele, P.1    Brduscha-Riem, K.2    Oehen, S.3    Odermatt, B.4    Zinkernagel, R.M.5    Hengartner, H.6    Pircher, H.7
  • 29
    • 13544262687 scopus 로고    scopus 로고
    • Distinct requirements for deletion versus anergy during CD8 T cell peripheral tolerance in vivo
    • Redmond, W. L., B. C. Marincek, and L. A. Sherman. 2005. Distinct requirements for deletion versus anergy during CD8 T cell peripheral tolerance in vivo. J. Immunol. 174: 2046-2053.
    • (2005) J. Immunol. , vol.174 , pp. 2046-2053
    • Redmond, W.L.1    Marincek, B.C.2    Sherman, L.A.3
  • 30
    • 0035656533 scopus 로고    scopus 로고
    • Preservation of motor function by inhibition of CD8+ virus peptide-specific T cells in Theiler's virus infection
    • Johnson, A. J., J. Upshaw, K. D. Pavelko, M. Rodriguez, and L. R. Pease. 2001. Preservation of motor function by inhibition of CD8+ virus peptide-specific T cells in Theiler's virus infection. FASEB J. 15: 2760-2762.
    • (2001) FASEB J. , vol.15 , pp. 2760-2762
    • Johnson, A.J.1    Upshaw, J.2    Pavelko, K.D.3    Rodriguez, M.4    Pease, L.R.5
  • 31
    • 0141427768 scopus 로고    scopus 로고
    • Clearance of Theiler's virus infection depends on the ability to generate a CD8+ T cell response against a single immunodominant viral peptide
    • Mendez-Fernandez, Y. V., A. J. Johnson, M. Rodriguez, and L. R. Pease. 2003. Clearance of Theiler's virus infection depends on the ability to generate a CD8+ T cell response against a single immunodominant viral peptide. Eur. J. Immunol. 33: 2501-2510.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 2501-2510
    • Mendez-Fernandez, Y.V.1    Johnson, A.J.2    Rodriguez, M.3    Pease, L.R.4
  • 32
    • 34447637424 scopus 로고    scopus 로고
    • CD8+ T cells directed against a viral peptide contribute to loss of motor function by disrupting axonal transport in a viral model of fulminant demyelination
    • Howe, C. L., D. Ure, J. D. Adelson, R. LaFrance-Corey, A. Johnson, and M. Rodriguez. 2007. CD8+ T cells directed against a viral peptide contribute to loss of motor function by disrupting axonal transport in a viral model of fulminant demyelination. J. Neuroimmunol. 188: 13-21.
    • (2007) J. Neuroimmunol. , vol.188 , pp. 13-21
    • Howe, C.L.1    Ure, D.2    Adelson, J.D.3    LaFrance-Corey, R.4    Johnson, A.5    Rodriguez, M.6
  • 33
    • 0242300038 scopus 로고    scopus 로고
    • Changing immunodominance patterns in antiviral CD8 T-cell responses after loss of epitope presentation or chronic antigenic stimulation
    • van der Most, R. G., K. Murali-Krishna, J. G. Lanier, E. J. Wherry, M. T. Puglielli, J. N. Blattman, A. Sette, and R. Ahmed. 2003. Changing immunodominance patterns in antiviral CD8 T-cell responses after loss of epitope presentation or chronic antigenic stimulation. Virology 315: 93-102.
    • (2003) Virology , vol.315 , pp. 93-102
    • Van Der Most, R.G.1    Murali-Krishna, K.2    Lanier, J.G.3    Wherry, E.J.4    Puglielli, M.T.5    Blattman, J.N.6    Sette, A.7    Ahmed, R.8
  • 35
    • 15244345880 scopus 로고    scopus 로고
    • Consequences of immunodominant epitope deletion for minor influenza virus-specific CD8+-T-cell responses
    • Andreansky, S. S., J. Stambas, P. G. Thomas, W. Xie, R. J. Webby, and P. C. Doherty. 2005. Consequences of immunodominant epitope deletion for minor influenza virus-specific CD8+-T-cell responses. J. Virol. 79: 4329-4339.
    • (2005) J. Virol. , vol.79 , pp. 4329-4339
    • Andreansky, S.S.1    Stambas, J.2    Thomas, P.G.3    Xie, W.4    Webby, R.J.5    Doherty, P.C.6
  • 37
    • 33846838637 scopus 로고    scopus 로고
    • Endogenous CD4(+) CD25(+) regulatory T cells have a limited role in the control of Trypanosoma cruzi infection in mice
    • Kotner, J., and R. Tarleton. 2007. Endogenous CD4(+) CD25(+) regulatory T cells have a limited role in the control of Trypanosoma cruzi infection in mice. Infect. Immun. 75: 861-869.
    • (2007) Infect. Immun. , vol.75 , pp. 861-869
    • Kotner, J.1    Tarleton, R.2
  • 38
    • 44449096726 scopus 로고    scopus 로고
    • IL-10: The master regulator of immunity to infection
    • Couper, K. N., D. G. Blount, and E. M. Riley. 2008. IL-10: the master regulator of immunity to infection. J. Immunol. 180: 5771-5777.
    • (2008) J. Immunol. , vol.180 , pp. 5771-5777
    • Couper, K.N.1    Blount, D.G.2    Riley, E.M.3
  • 39
    • 0025117462 scopus 로고
    • Depletion of CD8+ T cells increases susceptibility and reverses vaccine-induced immunity in mice infected with Trypanosoma cruzi
    • Tarleton, R. L. 1990. Depletion of CD8+ T cells increases susceptibility and reverses vaccine-induced immunity in mice infected with Trypanosoma cruzi. J. Immunol. 144: 717-724.
    • (1990) J. Immunol. , vol.144 , pp. 717-724
    • Tarleton, R.L.1
  • 40
    • 0026536194 scopus 로고
    • Susceptibility of beta 2-microglobulin-deficient mice to Trypanosoma cruzi infection
    • Tarleton, R. L., B. H. Koller, A. Latour, and M. Postan. 1992. Susceptibility of beta 2-microglobulin-deficient mice to Trypanosoma cruzi infection. Nature 356: 338-340.
    • (1992) Nature , vol.356 , pp. 338-340
    • Tarleton, R.L.1    Koller, B.H.2    Latour, A.3    Postan, M.4
  • 41
    • 0030051238 scopus 로고    scopus 로고
    • Trypanosoma cruzi infection in MHC-deficient mice: Further evidence for the role of both class I- And class II-restricted T cells in immune resistance and disease
    • Tarleton, R. L., M. J. Grusby, M. Postan, and L. H. Glimcher. 1996. Trypanosoma cruzi infection in MHC-deficient mice: further evidence for the role of both class I- and class II-restricted T cells in immune resistance and disease. Int. Immunol. 8: 13-22.
    • (1996) Int. Immunol. , vol.8 , pp. 13-22
    • Tarleton, R.L.1    Grusby, M.J.2    Postan, M.3    Glimcher, L.H.4
  • 42
    • 33645513235 scopus 로고    scopus 로고
    • Distinct kinetics of effector CD8+ cytotoxic T cells after infection with Trypanosoma cruzi in naive or vaccinated mice
    • Tzelepis, F., B. C. de Alencar, M. L. Penido, R. T. Gazzinelli, P. M. Persechini, and M. M. Rodrigues. 2006. Distinct kinetics of effector CD8+ cytotoxic T cells after infection with Trypanosoma cruzi in naive or vaccinated mice. Infect. Immun. 74: 2477-2481.
    • (2006) Infect. Immun. , vol.74 , pp. 2477-2481
    • Tzelepis, F.1    De Alencar, B.C.2    Penido, M.L.3    Gazzinelli, R.T.4    Persechini, P.M.5    Rodrigues, M.M.6
  • 43
    • 0031658742 scopus 로고    scopus 로고
    • A protective cytotoxic T cell response to a subdominant epitope is influenced by the stability of the MHC class I/peptide complex and the overall spectrum of viral peptides generated within infected cells
    • Gallimore, A., J. Hombach, T. Dumrese, H. G. Rammensee, R. M. Zinkernagel, and H. Hengartner. 1998. A protective cytotoxic T cell response to a subdominant epitope is influenced by the stability of the MHC class I/peptide complex and the overall spectrum of viral peptides generated within infected cells. Eur. J. Immunol. 28: 3301-3311.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 3301-3311
    • Gallimore, A.1    Hombach, J.2    Dumrese, T.3    Rammensee, H.G.4    Zinkernagel, R.M.5    Hengartner, H.6
  • 44
    • 0028930288 scopus 로고
    • Immunobiology of cytotoxic T-cell escape mutants of lymphocytic choriomeningitis virus
    • Moskophidis, D., and R. M. Zinkernagel. 1995. Immunobiology of cytotoxic T-cell escape mutants of lymphocytic choriomeningitis virus. J. Virol. 69: 2187-2193.
    • (1995) J. Virol. , vol.69 , pp. 2187-2193
    • Moskophidis, D.1    Zinkernagel, R.M.2
  • 46
    • 33750473417 scopus 로고    scopus 로고
    • CTL response compensation for the loss of an immunodominant class I-restricted HSV-1 determinant
    • Stock, A. T., C. M. Jones, W. R. Heath, and F. R. Carbone. 2006. CTL response compensation for the loss of an immunodominant class I-restricted HSV-1 determinant. Immunol. Cell Biol. 84: 543-550.
    • (2006) Immunol. Cell Biol. , vol.84 , pp. 543-550
    • Stock, A.T.1    Jones, C.M.2    Heath, W.R.3    Carbone, F.R.4
  • 47
    • 40049095195 scopus 로고    scopus 로고
    • Influence of a single viral epitope on T cell response and disease after infection of mice with respiratory syncytial virus
    • Vallbracht, S., B. Jessen, S. Mrusek, A. Enders, P. L. Collins, S. Ehl, and C. D. Krempl. 2007. Influence of a single viral epitope on T cell response and disease after infection of mice with respiratory syncytial virus. J. Immunol. 179: 8264-8273.
    • (2007) J. Immunol. , vol.179 , pp. 8264-8273
    • Vallbracht, S.1    Jessen, B.2    Mrusek, S.3    Enders, A.4    Collins, P.L.5    Ehl, S.6    Krempl, C.D.7
  • 48
    • 2642704191 scopus 로고    scopus 로고
    • Relationship among immunodominance of single CD8+ T cell epitopes, virus load, and kinetics of primary antiviral CTL response
    • Weidt, G., O. Utermöhlen, J. Heukeshoven, F. Lehmann-Grube, and W. Deppert. 1998. Relationship among immunodominance of single CD8+ T cell epitopes, virus load, and kinetics of primary antiviral CTL response. J. Immunol. 160: 2923-2931.
    • (1998) J. Immunol. , vol.160 , pp. 2923-2931
    • Weidt, G.1    Utermöhlen, O.2    Heukeshoven, J.3    Lehmann-Grube, F.4    Deppert, W.5
  • 49
    • 0032975871 scopus 로고    scopus 로고
    • Noncompetitive expansion of cytotoxic T lymphocytes specific for different antigens during bacterial infection
    • Vijh, S., I. M. Pilip, and E. G. Pamer. 1999. Noncompetitive expansion of cytotoxic T lymphocytes specific for different antigens during bacterial infection. Infect. Immun. 67: 1303-1309.
    • (1999) Infect. Immun. , vol.67 , pp. 1303-1309
    • Vijh, S.1    Pilip, I.M.2    Pamer, E.G.3
  • 50
    • 34249950141 scopus 로고    scopus 로고
    • Differential outcome of tolerance induction in naive versus activated Theiler's virus epitope-specific CD8+ cytotoxic T cells
    • Getts, M. T., B. S. Kim, and S. D. Miller. 2007. Differential outcome of tolerance induction in naive versus activated Theiler's virus epitope-specific CD8+ cytotoxic T cells. J. Virol. 81: 6584-6593.
    • (2007) J. Virol. , vol.81 , pp. 6584-6593
    • Getts, M.T.1    Kim, B.S.2    Miller, S.D.3
  • 51
    • 0036310249 scopus 로고    scopus 로고
    • b mice inhibits resistance to virus-induced demyelination
    • DOI 10.1128/JVI.76.15.7799-7811.2002
    • Lin, X., M. K. Njenga, A. J. Johnson, K. D. Pavelko, C. S. David, L. R. Pease, and M. Rodriguez. 2002. Transgenic expression of Theiler's murine encephalomyelitis virus genes in H-2(b) mice inhibits resistance to virus-induced demyelination. J. Virol. 76: 7799-7811. (Pubitemid 34761002)
    • (2002) Journal of Virology , vol.76 , Issue.15 , pp. 7799-7811
    • Lin, X.1    Njenga, M.K.2    Johnson, A.J.3    Pavelko, K.D.4    David, C.S.5    Pease, L.R.6    Rodriguez, M.7
  • 52
    • 43949122908 scopus 로고    scopus 로고
    • Anticapsid immunity level, not viral persistence level, correlates with the progression of Theiler's virus-induced demyelinating disease in viral P1-transgenic mice
    • Myoung, J., Y. Y. Bahk, H. S. Kang, M. C. Dal Canto, and B. S. Kim. 2008. Anticapsid immunity level, not viral persistence level, correlates with the progression of Theiler's virus-induced demyelinating disease in viral P1-transgenic mice. J. Virol. 82: 5606-5617.
    • (2008) J. Virol. , vol.82 , pp. 5606-5617
    • Myoung, J.1    Bahk, Y.Y.2    Kang, H.S.3    Dal Canto, M.C.4    Kim, B.S.5
  • 53
    • 33947510838 scopus 로고    scopus 로고
    • Genetic deletion of a single immunodominant T-cell response confers susceptibility to virus-induced demyelination
    • Pavelko, K. D., L. R. Pease, C. S. David, and M. Rodriguez. 2007. Genetic deletion of a single immunodominant T-cell response confers susceptibility to virus-induced demyelination. Brain Pathol. 17: 184-196.
    • (2007) Brain Pathol. , vol.17 , pp. 184-196
    • Pavelko, K.D.1    Pease, L.R.2    David, C.S.3    Rodriguez, M.4
  • 54
    • 49149084519 scopus 로고    scopus 로고
    • Absence of CTL responses to early viral antigens facilitates viral persistence
    • Schildknecht, A., S. Welti, M. B. Geuking, L. Hangartner, and M. van den Broek. 2008. Absence of CTL responses to early viral antigens facilitates viral persistence. J. Immunol. 180: 3113-3121.
    • (2008) J. Immunol. , vol.180 , pp. 3113-3121
    • Schildknecht, A.1    Welti, S.2    Geuking, M.B.3    Hangartner, L.4    Van Den Broek, M.5
  • 55
    • 0033059961 scopus 로고    scopus 로고
    • Thymic tolerance to only one viral protein reduces lymphocytic choriomeningitis virus-induced immunopathology and increases survival in perforin-deficient mice
    • von Herrath, M., B. Coon, D. Homann, T. Wolfe, and L. G. Guidotti. 1999. Thymic tolerance to only one viral protein reduces lymphocytic choriomeningitis virus-induced immunopathology and increases survival in perforin-deficient mice. J. Virol. 73: 5918-5925.
    • (1999) J. Virol. , vol.73 , pp. 5918-5925
    • Von Herrath, M.1    Coon, B.2    Homann, D.3    Wolfe, T.4    Guidotti, L.G.5
  • 57
    • 67649403394 scopus 로고    scopus 로고
    • Common strategies for antigenic variation by bacterial, fungal and protozoan pathogens
    • Deitsch, K. W., S. A. Lukehart, and J. R. Stringer. 2009. Common strategies for antigenic variation by bacterial, fungal and protozoan pathogens. Nat. Rev. Microbiol. 7: 493-503.
    • (2009) Nat. Rev. Microbiol. , vol.7 , pp. 493-503
    • Deitsch, K.W.1    Lukehart, S.A.2    Stringer, J.R.3
  • 58
    • 0031114082 scopus 로고    scopus 로고
    • Delivery by Trypanosoma cruzi of proteins into the MHC class I antigen processing and presentation pathway
    • Garg, N., M. P. Nunes, and R. L. Tarleton. 1997. Delivery by Trypanosoma cruzi of proteins into the MHC class I antigen processing and presentation pathway. J. Immunol. 158: 3293-3302.
    • (1997) J. Immunol. , vol.158 , pp. 3293-3302
    • Garg, N.1    Nunes, M.P.2    Tarleton, R.L.3
  • 59
    • 0031278587 scopus 로고    scopus 로고
    • The surface glycoproteins of Trypanosoma cruzi encode a superfamily of variant T cell epitopes
    • Kahn, S. J., and M. Wleklinski. 1997. The surface glycoproteins of Trypanosoma cruzi encode a superfamily of variant T cell epitopes. J. Immunol. 159: 4444-4451.
    • (1997) J. Immunol. , vol.159 , pp. 4444-4451
    • Kahn, S.J.1    Wleklinski, M.2
  • 62
    • 4143141923 scopus 로고    scopus 로고
    • Antigenic variation in Trypanosoma brucei: Facts, challenges and mysteries
    • Pays, E., L. Vanhamme, and D. Pérez-Morga. 2004. Antigenic variation in Trypanosoma brucei: facts, challenges and mysteries. Curr. Opin. Microbiol. 7: 369-374.
    • (2004) Curr. Opin. Microbiol. , vol.7 , pp. 369-374
    • Pays, E.1    Vanhamme, L.2    Pérez-Morga, D.3
  • 63
    • 36148956192 scopus 로고    scopus 로고
    • Trypanosoma cruzi infection from the view of CD8+ T cell immunity - An infection model for developing T cell vaccine
    • Miyahira, Y. 2008. Trypanosoma cruzi infection from the view of CD8+ T cell immunity - an infection model for developing T cell vaccine. Parasitol. Int. 57: 38-48.
    • (2008) Parasitol. Int. , vol.57 , pp. 38-48
    • Miyahira, Y.1
  • 65
    • 0032169558 scopus 로고    scopus 로고
    • Human infection with Trypanosoma cruzi induces parasite antigen-specific cytotoxic T lymphocyte responses
    • Wizel, B., M. Palmieri, C. Mendoza, B. Arana, J. Sidney, A. Sette, and R. Tarleton. 1998. Human infection with Trypanosoma cruzi induces parasite antigen-specific cytotoxic T lymphocyte responses. J. Clin. Invest. 102: 1062-1071.
    • (1998) J. Clin. Invest. , vol.102 , pp. 1062-1071
    • Wizel, B.1    Palmieri, M.2    Mendoza, C.3    Arana, B.4    Sidney, J.5    Sette, A.6    Tarleton, R.7
  • 66
    • 0034118186 scopus 로고    scopus 로고
    • The SA85-1.1 protein of the Trypanosoma cruzi trans-sialidase superfamily is a dominant T-cell antigen
    • Millar, A. E., and S. J. Kahn. 2000. The SA85-1.1 protein of the Trypanosoma cruzi trans-sialidase superfamily is a dominant T-cell antigen. Infect. Immun. 68: 3574-3580.
    • (2000) Infect. Immun. , vol.68 , pp. 3574-3580
    • Millar, A.E.1    Kahn, S.J.2
  • 67
    • 40749153135 scopus 로고    scopus 로고
    • Cross-species immunity in malaria vaccine development: Two, three, or even four for the price of one?
    • Douradinha, B., M. M. Mota, A. J. Luty, and R. W. Sauerwein. 2008. Cross-species immunity in malaria vaccine development: two, three, or even four for the price of one? Infect. Immun. 76: 873-878.
    • (2008) Infect. Immun. , vol.76 , pp. 873-878
    • Douradinha, B.1    Mota, M.M.2    Luty, A.J.3    Sauerwein, R.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.