A protective cytotoxic T cell response to a subdominant epitope is influenced by the stability of the MHC class I/peptide complex and the overall spectrum of viral peptides generated within infected cells

European Journal of Immunology

Volumn 28, Issue 10, 1998, Pages 3301-3311

  Gallimore, Awen ^a,c   Hombach, Joachim ^a,d   Dumrese, Tilman ^b   Rammensee, Hans Georg ^b   Zinkernagel, Rolf M ^a   Hengartner, Hans ^a  

^a INSTITUTE OF EXPERIMENTAL IMMUNOLOGY   (Switzerland)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^d WORLD HEALTH ORGANIZATION   (Switzerland)

Author keywords

Antiviral protection; Cytotoxic lymphocyte; Lymphocytic choriomeningitis virus; Peptide elution

Indexed keywords

ASPARAGINE; LEUCINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; SERINE; VALINE; VIRUS PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN STABILITY; VACCINATION;

ANIMALS; BASE SEQUENCE; CELL LINE; DNA; EPITOPE MAPPING; EPITOPES, T-LYMPHOCYTE; GENETIC VECTORS; H-2 ANTIGENS; IMMUNIZATION; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; PEPTIDES; RECOMBINANT FUSION PROTEINS; T-LYMPHOCYTES, CYTOTOXIC; VACCINIA VIRUS; VIRAL PROTEINS;

EID: 0031658742     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199810)28:10<3301::AID-IMMU3301>3.0.CO;2-Q     Document Type: Article

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