Nuclear proteome analysis of cisplatin-treated HeLa cells

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 691, Issue 1-2, 2010, Pages 1-8

  Wu, Wei ^a,b   Yan, Chunlan ^a   Gan, Tieer ^a   Chen, Zhanghui ^a   Lu, Xianghong ^c   Duerksen Hughes, Penelope J ^d   Zhu, Xinqiang ^a   Yang, Jun ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b INSTITUTE OF MATERIA MEDICA   (China)

^c LISHUI PEOPLE S HOSPITAL   (China)

^d LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alternative splicing; Cisplatin; DNA damage; Nuclear proteome; Two dimensional electrophoresis

Indexed keywords

CISPLATIN; DNA; FAS ANTIGEN; MESSENGER RNA; PROTEOME;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CELL CYCLE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DRUG RESPONSE; GLYCOLYSIS; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; UTERINE CERVIX CARCINOMA;

ALTERNATIVE SPLICING; ANTIGENS, CD95; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL DEATH; CISPLATIN; DNA DAMAGE; GENE EXPRESSION REGULATION, NEOPLASTIC; HELA CELLS; HUMANS; NUCLEAR PROTEINS; PROTEOME;

EID: 77956169692     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2010.06.002     Document Type: Article

References (49)

1. Rosenberg B., VanCamp L., Trosko J.E., Mansour V.H. Platinum compounds: a new class of potent antitumour agents. Nature 1969, 222:385-386.
2. Johnson N.P., Butour J.L., Villani G., Wimmer F.L., Defais M., Pierson V., Brabec V. Metal antitumor compounds: the mechanism of action of platinum complexes. Progress Clin. Biochem. Med. 1989, 10:1-24.
3. Chvalova K., Brabec V., Kasparkova J. Mechanism of the formation of DNA-protein cross-links by antitumor cisplatin. Nucleic Acids Res. 2007, 35:1812-1821.
4. Eastman A. The formation, isolation and characterization of DNA adducts produced by anticancer platinum complexes. Pharmacol. Ther. 1987, 34:155-166.
5. Yu Y., Zhu W., Diao H., Zhou C., Chen F.F., Yang J. A comparative study of using comet assay and gammaH2AX foci formation in the detection of N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA damage. Toxicol. In Vitro 2006, 20:959-965.
6. Kitao H., Yuan Z.M. Regulation of ionizing radiation-induced Rad52 nuclear foci formation by c-Abl-mediated phosphorylation. J. Biol. Chem. 2002, 277:48944-48948.
7. Kumari A., Schultz N., Helleday T. p53 protects from replication-associated DNA double-strand breaks in mammalian cells. Oncogene 2004, 23:2324-2329.
8. Mabuchi S., Ohmichi M., Nishio Y., Hayasaka T., Kimura A., Ohta T., Saito M., Kawagoe J., Takahashi K., Yada-Hashimoto N., Sakata M., Motoyama T., Kurachi H., Tasaka K., Murata Y. Inhibition of NFkappaB increases the efficacy of cisplatin in in vitro and in vivo ovarian cancer models. J. Biol. Chem. 2004, 279:23477-23485.
9. Pedraza-Alva G., Koulnis M., Charland C., Thornton T., Clements J.L., Schlissel M.S., Rincon M. Activation of p38 MAP kinase by DNA double-strand breaks in V(D)J recombination induces a G2/M cell cycle checkpoint. EMBO J. 2006, 25:763-773.
10. Rogakou E.P., Boon C., Redon C., Bonner W.M. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol. 1999, 146:905-916.
11. Rogakou E.P., Pilch D.R., Orr A.H., Ivanova V.S., Bonner W.M. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 1998, 273:5858-5868.
12. Chowdhury D., Keogh M.C., Ishii H., Peterson C.L., Buratowski S., Lieberman J. γ-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair. Mol. Cell 2005, 20:801-809.
13. Kusch T., Florens L., Macdonald W.H., Swanson S.K., Glaser R.L., Yates J.R., 3rd S.M., Abmayr M.P., Washburn J.L., Workman Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions. Science 2004, 306:2084-2087.
14. Paull T.T., Rogakou E.P., Yamazaki V., Kirchgessner C.U., Gellert M., Bonner W.M. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol. 2000, 10:886-895.
15. Rao V.A., Agama K., Holbeck S., Pommier Y. Batracylin (NSC 320846), a dual inhibitor of DNA topoisomerases I and II induces histone gamma-H2AX as a biomarker of DNA damage. Cancer Res. 2007, 67:9971-9979.
16. Redon C.E, Dickey J.S., Bonner W.M., Sedelnikova O.A. γ-H2AX as a biomarker of DNA damage induced by ionizing radiation in human peripheral blood lymphocytes and artificial skin. Adv. Space Res. 2009, 43:1171-1178.
17. Vercauteren F.G., Arckens L., Quirion R. Applications and current challenges of proteomic approaches, focusing on two-dimensional electrophoresis. Amino Acids 2007, 33:405-414.
18. Le Moguen K, Lincet H., Deslandes E., Hubert-Roux M., Lange C., Poulain L., Gauduchon P., Baudin B. Comparative proteomic analysis of cisplatin sensitive IGROV1 ovarian carcinoma cell line and its resistant counterpart IGROV1-R10. Proteomics 2006, 6:5183-5192.
19. Le Moguen K., Lincet H., Marcelo P., Lemoisson E., Heutte N., Duval M., Poulain L., Vinh J., Gauduchon P., Baudin B. A proteomic kinetic analysis of IGROV1 ovarian carcinoma cell line response to cisplatin treatment. Proteomics 2007, 7:4090-4101.
20. Schmidt F., Hustoft H.K., Strozynski M., Dimmler C., Rudel T., Thiede B. Quantitative proteome analysis of cisplatin-induced apoptotic Jurkat T cells by stable isotope labeling with amino acids in cell culture, SDS-PAGE, and LC-MALDI-TOF/TOF MS. Electrophoresis 2007, 28:4359-4368.
21. Fox A.H, Lam Y.W., Leung A.K., Lyon C.E., Andersen J., Mann M., Lamond A.I. Paraspeckles: a novel nuclear domain. Curr. Biol. 2002, 12:13-25.
22. Dong Z., Hu H., Chen W., Li Z., Liu G., Yang J. Heat shock does not induce gammaH2AX foci formation but protects cells from N-methyl-N'-nitro-N-nitrosoguanidine-induced genotoxicity. Mutat. Res. 2007, 629:40-48.
23. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
24. Sun G., Xu X., Wang Y., Shen X., Chen Z., Yang J. Mycoplasma pneumoniae infection induces reactive oxygen species and DNA damage in A549 human lung carcinoma cells. Infect. Immun. 2008, 76:4405-4413.
25. Shevchenko A., Wilm M., Vorm O., Mann M. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem. 1996, 68:850-858.
26. Josic D., Brown M.K., Huang F., Lim Y.P., Rucevic M., Clifton J.G., Hixson D.C. Proteomic characterization of inter-alpha inhibitor proteins from human plasma. Proteomics 2006, 6:2874-2885.
27. Filippov V., Schmidt E.L., Filippova M., Duerksen-Hughes P.J. Splicing and splice factor SRp55 participate in the response to DNA damage by changing isoform ratios of target genes. Gene 2008, 420:34-41.
28. Manju K., Muralikrishna B., Parnaik V.K. Expression of disease-causing lamin A mutants impairs the formation of DNA repair foci. J. Cell Sci. 2006, 119:2704-2714.
29. di Masi A., D'Apice M.R., Ricordy R., Tanzarella C., Novelli G. The R527H mutation in LMNA gene causes an increased sensitivity to ionizing radiation. Cell Cycle 2008, 7:2030-2037.
30. Kim E.M., Burke D.J. DNA damage activates the SAC in an ATM/ATR-dependent manner, independently of the kinetochore. PLoS Genet. 2008, 4:e1000015.
31. Matsuoka S, Ballif B.A., Smogorzewska A., McDonald E.R., Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N., Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 2007, 316:1160-1166.
32. Filippov V., Filippova M., Duerksen-Hughes P.J. The early response to DNA damage can lead to activation of alternative splicing activity resulting in CD44 splice pattern changes. Cancer Res. 2007, 67:7621-7630.
33. Marengo M.S., Wassarman D.A. A DNA damage signal activates and derepresses exon inclusion in Drosophila TAF1 alternative splicing. RNA 2008, 14:1681-1695.
34. Johnson J.M., Castle J., Garrett-Engele P., Kan Z., Loerch P.M., Armour C.D., Santos R., Schadt E.E., Stoughton R., Shoemaker D.D. Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. Science 2003, 302:2141-2144.
35. Black D.L. Mechanisms of alternative pre-messenger RNA splicing. Annu. Rev. Biochem. 2003, 72:291-336.
36. Yan C., Wu W., Li H., Zhang G., Duerksen-Hughes P.J., Zhu X., Yang J. Benzo[a]pyrene treatment leads to changes in nuclear protein expression and alternative splicing. Mutat. Res. 2010, 686:47-56.
37. Castagna A., Antonioli P., Astner H., Hamdan M., Righetti S.C., Perego P., Zunino F., Righetti P.G. A proteomic approach to cisplatin resistance in the cervix squamous cell carcinoma cell line A431. Proteomics 2004, 4:3246-3267.
38. Coling D.E., Ding D., Young R., Lis M., Stofko E., Blumenthal K.M., Salvi R.J. Proteomic analysis of cisplatin-induced cochlear damage: methods and early changes in protein expression. Hear. Res. 2007, 226:140-156.
39. Gonzalez-Suarez I., Redwood A.B., Perkins S.M., Vermolen B., Lichtensztejin D., Grotsky D.A., Morgado-Palacin L., Gapud E.J., Sleckman B.P., Sullivan T., Sage J., Stewart C.L., Mai S., Gonzalo S. Novel roles for A-type lamins in telomere biology and the DNA damage response pathway. EMBO J. 2009, 28:2414-2427.
40. Kalitsis P., Earle E., Fowler K.J., Choo K.H. Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis. Genes Dev. 2000, 14:2277-2282.
41. Logarinho E., Bousbaa H., Dias J.M., Lopes C., Amorim I., Antunes-Martins A., Sunkel C.E. Different spindle checkpoint proteins monitor microtubule attachment and tension at kinetochores in Drosophila cells. J. Cell Sci. 2004, 117:1757-1771.
42. Perera D., Tilston V., Hopwood J.A., Barchi M., Boot-Handford R.P., Taylor S.S. Bub1 maintains centromeric cohesion by activation of the spindle checkpoint. Dev. Cell 2007, 13:566-579.
43. Kameoka S., Duque P., Konarska M.M. p54(nrb) associates with the 5' splice site within large transcription/splicing complexes. EMBO J. 2004, 23:1782-1791.
44. Kuwahara S., Ikei A., Taguchi Y., Tabuchi Y., Fujimoto N., Obinata M., Uesugi S., Kurihara Y. PSPC1, NONO, and SFPQ are expressed in mouse Sertoli cells and may function as coregulators of androgen receptor-mediated transcription. Biol. Reprod. 2006, 75:352-359.
45. Myojin R., Kuwahara S., Yasaki T., Matsunaga T., Sakurai T., Kimura M., Uesugi S., Kurihara Y. Expression and functional significance of mouse paraspeckle protein 1 on spermatogenesis. Biol. Reprod. 2004, 71:926-932.
46. Riches L.C., Lynch A.M., Gooderham N.J. Early events in the mammalian response to DNA double-strand breaks. Mutagenesis 2008, 23:331-339.
47. Chen Z., Gore B.B., Long H., Ma L., Tessier-Lavigne M. Alternative splicing of the Robo3 axon guidance receptor governs the midline switch from attraction to repulsion. Neuron 2008, 58:325-332.
48. Jiang Z.H., Wu J.Y. Alternative splicing and programmed cell death. Proc. Soc. Exp. Biol. Med. 1999, 220:64-72.
49. Scotlandi K., Zuntini M., Manara M.C., Sciandra M., Rocchi A., Benini S., Nicoletti G., Bernard G., Nanni P., Lollini P.L., Bernard A., Picci P. CD99 isoforms dictate opposite functions in tumour malignancy and metastases by activating or repressing c-Src kinase activity. Oncogene 2007, 26:6604-6618.