-
1
-
-
33750705653
-
A century of Alzheimer's disease
-
Goedert, M. and Spillantini, M.G. (2006) A century of Alzheimer's disease. Science 314, 777-781
-
(2006)
Science
, vol.314
, pp. 777-781
-
-
Goedert, M.1
Spillantini, M.G.2
-
2
-
-
0025863618
-
Neuropathological staging of Alzheimer-related changes
-
Braak, H. and Braak, E. (1991) Neuropathological staging of Alzheimer-related changes. Acta Neuropathol. 82, 239-259
-
(1991)
Acta Neuropathol.
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
3
-
-
0037172826
-
Phases of Aβ-deposition in the human brain and its relevance for the development of AD
-
Thal, D.R., Rub, U., Orantes, M. and Braak, H. (2002) Phases of Aβ-deposition in the human brain and its relevance for the development of AD. Neurology 58, 1791-1800
-
(2002)
Neurology
, vol.58
, pp. 1791-1800
-
-
Thal, D.R.1
Rub, U.2
Orantes, M.3
Braak, H.4
-
4
-
-
84880188055
-
Immunological demonstration of tau protein in neurofibrillary tangles of Alzheimer's disease
-
Brion, J.-P. (2006) Immunological demonstration of tau protein in neurofibrillary tangles of Alzheimer's disease. J. Alzheimer's Dis. 9, 177-185
-
(2006)
J. Alzheimer's Dis.
, vol.9
, pp. 177-185
-
-
Brion, J.-P.1
-
5
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy, J. and Selkoe, D.J. (2002) The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297, 353-356
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
6
-
-
0026740795
-
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
-
Arriagada, P.V., Growdon, J.H., Hedley-Whyte, E.T. and Hyman, B.T. (1992) Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology 42, 631-639
-
(1992)
Neurology
, vol.42
, pp. 631-639
-
-
Arriagada, P.V.1
Growdon, J.H.2
Hedley-Whyte, E.T.3
Hyman, B.T.4
-
7
-
-
34548036227
-
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
-
Ballatore, C., Lee, V.M. Y. and Trojanowski, J.Q. (2007) Tau-mediated neurodegeneration in Alzheimer's disease and related disorders. Nat. Rev. Neurosci. 8, 663-672
-
(2007)
Nat. Rev. Neurosci.
, vol.8
, pp. 663-672
-
-
Ballatore, C.1
Lee, V.M.Y.2
Trojanowski, J.Q.3
-
8
-
-
61649085621
-
Tau pathophysiology in neurodegeneration: A tangled issue
-
Spires-Jones, T.L., Stoothoff, W.H., de Calignon, A., Jones, P.B. and Hyman, B.T. (2009) Tau pathophysiology in neurodegeneration: a tangled issue. Trends Neurosci. 32, 150-159
-
(2009)
Trends Neurosci.
, vol.32
, pp. 150-159
-
-
Spires-Jones, T.L.1
Stoothoff, W.H.2
De Calignon, A.3
Jones, P.B.4
Hyman, B.T.5
-
9
-
-
45749151056
-
Animal models of Alzheimer's disease and frontotemporal dementia
-
Gotz, J. and Ittner, L.M. (2008) Animal models of Alzheimer's disease and frontotemporal dementia. Nat. Rev. Neurosci. 9, 532-544
-
(2008)
Nat. Rev. Neurosci.
, vol.9
, pp. 532-544
-
-
Gotz, J.1
Ittner, L.M.2
-
10
-
-
0024804051
-
Neurofibrillary degeneration and neuronal loss in Alzheimer's disease
-
Bondareff, W., Mountjoy, C.Q., Roth, M. and Hauser, D.L. (1989) Neurofibrillary degeneration and neuronal loss in Alzheimer's disease. Neurobiol. Aging 10, 709-715
-
(1989)
Neurobiol. Aging
, vol.10
, pp. 709-715
-
-
Bondareff, W.1
Mountjoy, C.Q.2
Roth, M.3
Hauser, D.L.4
-
11
-
-
0344653664
-
Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease
-
Gómez-Isla, T., Hollister, R., West, H., Mui, S., Growdon, J.H., Petersen, R.C., Parisi, J.E. and Hyman, B.T. (1997) Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease. Ann. Neurol. 41, 17-24
-
(1997)
Ann. Neurol.
, vol.41
, pp. 17-24
-
-
Gómez-Isla, T.1
Hollister, R.2
West, H.3
Mui, S.4
Growdon, J.H.5
Petersen, R.C.6
Parisi, J.E.7
Hyman, B.T.8
-
12
-
-
66249141245
-
Age, neuropathology, and dementia
-
Savva, G.M., Wharton, S.B., Ince, P.G., Forster, G., Matthews, F.E. and Brayne, C. (2009) Age, neuropathology, and dementia. N. Engl. J. Med. 360, 2302-2309
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 2302-2309
-
-
Savva, G.M.1
Wharton, S.B.2
Ince, P.G.3
Forster, G.4
Matthews, F.E.5
Brayne, C.6
-
13
-
-
33746652117
-
Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits
-
Schindowski, K., Bretteville, A., Leroy, K., Begard, S., Brion, J.-P., Hamdane, M. and Buée, L. (2006) Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits. Am. J. Pathol. 169, 599-616
-
(2006)
Am. J. Pathol.
, vol.169
, pp. 599-616
-
-
Schindowski, K.1
Bretteville, A.2
Leroy, K.3
Begard, S.4
Brion, J.-P.5
Hamdane, M.6
Buée, L.7
-
14
-
-
33847199377
-
A decade of tau transgenic animal models and beyond
-
Gotz, J., Deters, N., Doldissen, A., Bokhari, L., Ke, Y.Z., Wiesner, A., Schonrock, N. and Ittner, L.M. (2007) A decade of tau transgenic animal models and beyond. Brain Pathol. 17, 91-103
-
(2007)
Brain Pathol.
, vol.17
, pp. 91-103
-
-
Gotz, J.1
Deters, N.2
Doldissen, A.3
Bokhari, L.4
Ke, Y.Z.5
Wiesner, A.6
Schonrock, N.7
Ittner, L.M.8
-
15
-
-
35748954923
-
The β-propensity of Tau determines aggregation and synaptic loss in inducible mouse models of tauopathy
-
Eckermann, K., Mocanu, M.M., Khlistunova, I., Biernat, J., Nissen, A., Hofmann, A., Schonig, K., Bujard, H., Haemisch, A., Mandelkow, E. et al. (2007) The β-propensity of Tau determines aggregation and synaptic loss in inducible mouse models of tauopathy. J. Biol. Chem. 282, 31755-31765
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 31755-31765
-
-
Eckermann, K.1
Mocanu, M.M.2
Khlistunova, I.3
Biernat, J.4
Nissen, A.5
Hofmann, A.6
Schonig, K.7
Bujard, H.8
Haemisch, A.9
Mandelkow, E.10
-
16
-
-
33646519920
-
Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy
-
Spires, T.L., Orne, J.D., SantaCruz, K., Pitstick, R., Carlson, G.A., Ashe, K.H. and Hyman, B.T. (2006) Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy. Am. J. Pathol. 168, 1598-1607
-
(2006)
Am. J. Pathol.
, vol.168
, pp. 1598-1607
-
-
Spires, T.L.1
Orne, J.D.2
SantaCruz, K.3
Pitstick, R.4
Carlson, G.A.5
Ashe, K.H.6
Hyman, B.T.7
-
17
-
-
22344438508
-
Tau suppression in a neurodegenerative mouse model improves memory function
-
SantaCruz, K., Lewis, J., Spires, T., Paulson, J., Kotilinek, L., Ingelsson, M., Guimaraes, A., DeTure, M., Ramsden, M., McGowan, E. et al. (2005) Tau suppression in a neurodegenerative mouse model improves memory function. Science 309, 476-481
-
(2005)
Science
, vol.309
, pp. 476-481
-
-
SantaCruz, K.1
Lewis, J.2
Spires, T.3
Paulson, J.4
Kotilinek, L.5
Ingelsson, M.6
Guimaraes, A.7
DeTure, M.8
Ramsden, M.9
McGowan, E.10
-
18
-
-
38549120646
-
In vivo imaging reveals dissociation between caspase activation and acute neuronal death in tangle-bearing neurons
-
Spires-Jones, T.L., de Calignon, A., Matsui, T., Zehr, C., Pitstick, R., Wu, H.Y., Osetek, J.D., Jones, P.B., Bacskai, B.J., Feany, M.B. et al. (2008) In vivo imaging reveals dissociation between caspase activation and acute neuronal death in tangle-bearing neurons. J. Neurosci. 28, 862-867
-
(2008)
J. Neurosci.
, vol.28
, pp. 862-867
-
-
Spires-Jones, T.L.1
De Calignon, A.2
Matsui, T.3
Zehr, C.4
Pitstick, R.5
Wu, H.Y.6
Osetek, J.D.7
Jones, P.B.8
Bacskai, B.J.9
Feany, M.B.10
-
19
-
-
34548829896
-
Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice
-
Leroy, K., Bretteville, A., Schindowski, K., Gilissen, E., Authelet, M., De Decker, R., Yilmaz, Z., Buée, L. and Brion, J.-P. (2007) Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice. Am. J. Pathol. 171, 976-992
-
(2007)
Am. J. Pathol.
, vol.171
, pp. 976-992
-
-
Leroy, K.1
Bretteville, A.2
Schindowski, K.3
Gilissen, E.4
Authelet, M.5
De Decker, R.6
Yilmaz, Z.7
Buée, L.8
Brion, J.-P.9
-
20
-
-
77049116286
-
Lithium treatment arrests the development of neurofibrillary tangles in mutant tau transgenic mice with advanced neurofibrillary pathology
-
Leroy, K., Ando, K., Heraud, C., Yilmaz, Z., Authelet, M., Boeynaems, J.M., Buée, L., De Decker, R. and Brion, J.-P. (2010) Lithium treatment arrests the development of neurofibrillary tangles in mutant tau transgenic mice with advanced neurofibrillary pathology. J. Alzheimer's Dis. 19, 705-719
-
(2010)
J. Alzheimer's Dis.
, vol.19
, pp. 705-719
-
-
Leroy, K.1
Ando, K.2
Heraud, C.3
Yilmaz, Z.4
Authelet, M.5
Boeynaems, J.M.6
Buée, L.7
De Decker, R.8
Brion, J.-P.9
-
21
-
-
77955938694
-
Deletion of murine tau gene increases tau aggregation in a human mutant tau transgenic mouse model
-
Ando, K., Leroy, K., Heraud, C., Kabova, A., Yilmaz, Z., Authelet, M., Suain, V., De Decker, R. and Brion, J.-P. (2010) Deletion of murine tau gene increases tau aggregation in a human mutant tau transgenic mouse model. Biochem. Soc. Trans. 38, 1001-1005
-
(2010)
Biochem. Soc. Trans.
, vol.38
, pp. 1001-1005
-
-
Ando, K.1
Leroy, K.2
Heraud, C.3
Kabova, A.4
Yilmaz, Z.5
Authelet, M.6
Suain, V.7
De Decker, R.8
Brion, J.-P.9
-
22
-
-
0035958642
-
Tauopathy in Drosophila: Neurodegeneration without neurofibrillary tangles
-
Wittmann, C.W., Wszolek, M.F., Shulman, J.M., Salvaterra, P.M., Lewis, J., Hutton, M. and Feany, M.B. (2001) Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles. Science 293, 711-714
-
(2001)
Science
, vol.293
, pp. 711-714
-
-
Wittmann, C.W.1
Wszolek, M.F.2
Shulman, J.M.3
Salvaterra, P.M.4
Lewis, J.5
Hutton, M.6
Feany, M.B.7
-
23
-
-
0037118247
-
Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila
-
Jackson, G.R., Wiedau-Pazos, M., Sang, T.K., Wagle, N., Brown, C.A., Massachi, S. and Geschwind, D.H. (2002) Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila. Neuron 34, 509-519
-
(2002)
Neuron
, vol.34
, pp. 509-519
-
-
Jackson, G.R.1
Wiedau-Pazos, M.2
Sang, T.K.3
Wagle, N.4
Brown, C.A.5
Massachi, S.6
Geschwind, D.H.7
-
24
-
-
67349142329
-
Mechanisms of tau-induced neurodegeneration
-
Iqbal, K., Liu, F., Gong, C.X., Alonso, A.D. and Grundke-Iqbal, I. (2009) Mechanisms of tau-induced neurodegeneration. Acta Neuropathol. 118, 53-69
-
(2009)
Acta Neuropathol.
, vol.118
, pp. 53-69
-
-
Iqbal, K.1
Liu, F.2
Gong, C.X.3
Alonso, A.D.4
Grundke-Iqbal, I.5
-
25
-
-
0037111833
-
Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease
-
Fath, T., Eidenmüller, J. and Brandt, R. (2002) Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease. J. Neurosci. 22, 9733-9741
-
(2002)
J. Neurosci.
, vol.22
, pp. 9733-9741
-
-
Fath, T.1
Eidenmüller, J.2
Brandt, R.3
-
26
-
-
34147125835
-
Accumulation of pathological tau species and memory loss in a conditional model of tauopathy
-
Berger, Z., Roder, H., Hanna, A., Carlson, A., Rangachari, V., Yue, M., Wszolek, Z., Ashe, K., Knight, J., Dickson, D. et al. (2007) Accumulation of pathological tau species and memory loss in a conditional model of tauopathy. J. Neurosci. 27, 3650-3662
-
(2007)
J. Neurosci.
, vol.27
, pp. 3650-3662
-
-
Berger, Z.1
Roder, H.2
Hanna, A.3
Carlson, A.4
Rangachari, V.5
Yue, M.6
Wszolek, Z.7
Ashe, K.8
Knight, J.9
Dickson, D.10
-
27
-
-
67650077008
-
Transmission and spreading of tauopathy in transgenic mouse brain
-
Clavaguera, F., Bolmont, T., Crowther, R.A., Abramowski, D., Frank, S., Probst, A., Fraser, G., Stalder, A.K., Beibel, M., Staufenbiel, M. et al. (2009) Transmission and spreading of tauopathy in transgenic mouse brain. Nat. Cell Biol. 11, 909-913
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 909-913
-
-
Clavaguera, F.1
Bolmont, T.2
Crowther, R.A.3
Abramowski, D.4
Frank, S.5
Probst, A.6
Fraser, G.7
Stalder, A.K.8
Beibel, M.9
Staufenbiel, M.10
-
28
-
-
33846538660
-
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
-
Yoshiyama, Y., Higuchi, M., Zhang, B., Huang, S.M., Iwata, N., Saido, T.C., Maeda, J., Suhara, T., Trojanowski, J.Q. and Lee, V.M.Y. (2007) Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model. Neuron 53, 337-351
-
(2007)
Neuron
, vol.53
, pp. 337-351
-
-
Yoshiyama, Y.1
Higuchi, M.2
Zhang, B.3
Huang, S.M.4
Iwata, N.5
Saido, T.C.6
Maeda, J.7
Suhara, T.8
Trojanowski, J.Q.9
Lee, V.M.Y.10
-
29
-
-
2542632693
-
Looting for the link between plaques and tangles
-
Duyckaerts, C. (2004) Looting for the link between plaques and tangles. Neurobiol. Aging 25, 735-739
-
(2004)
Neurobiol. Aging
, vol.25
, pp. 735-739
-
-
Duyckaerts, C.1
-
30
-
-
56349119351
-
Linking aβ and tau in late-onset Alzheimer's disease: A dual pathway hypothesis
-
Small, S.A. and Duff, K. (2008) Linking Aβ and tau in late-onset Alzheimer's disease: a dual pathway hypothesis. Neuron 60, 534-542
-
(2008)
Neuron
, vol.60
, pp. 534-542
-
-
Small, S.A.1
Duff, K.2
-
31
-
-
0037126952
-
Increased tau phosphorylation but absence of formation of neurofibrillary tangles in mice double transgenic for human tau and Alzheimer mutant (M146L) presenilin-1
-
Boutajangout, A., Leroy, K., Touchet, N., Authelet, M., Blanchard, V., Tremp, G., Pradier, L. and Brion, J.-P. (2002) Increased tau phosphorylation but absence of formation of neurofibrillary tangles in mice double transgenic for human tau and Alzheimer mutant (M146L) presenilin-1. Neurosci. Lett. 318, 29-33
-
(2002)
Neurosci. Lett.
, vol.318
, pp. 29-33
-
-
Boutajangout, A.1
Leroy, K.2
Touchet, N.3
Authelet, M.4
Blanchard, V.5
Tremp, G.6
Pradier, L.7
Brion, J.-P.8
-
32
-
-
1642578930
-
Cytoskeletal abnormalities in mice transgenic for human tau and familial Alzheimer's disease mutants of APP and presenilin-1
-
Boutajangout, A., Authelet, M., Blanchard, V., Touchet, N., Tremp, G., Pradier, L. and Brion, J.-P. (2004) Cytoskeletal abnormalities in mice transgenic for human tau and familial Alzheimer's disease mutants of APP and presenilin-1. Neurobiol. Dis. 15, 47-60
-
(2004)
Neurobiol. Dis.
, vol.15
, pp. 47-60
-
-
Boutajangout, A.1
Authelet, M.2
Blanchard, V.3
Touchet, N.4
Tremp, G.5
Pradier, L.6
Brion, J.-P.7
-
33
-
-
17944382037
-
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
-
Lewis, J., Dickson, D.W., Lin, W.L., Chisholm, L., Corral, A., Jones, G., Yen, S.H., Sahara, N., Skipper, L., Yager, D. et al. (2001) Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science 293, 1487-1491
-
(2001)
Science
, vol.293
, pp. 1487-1491
-
-
Lewis, J.1
Dickson, D.W.2
Lin, W.L.3
Chisholm, L.4
Corral, A.5
Jones, G.6
Yen, S.H.7
Sahara, N.8
Skipper, L.9
Yager, D.10
-
34
-
-
12344306018
-
Characterization of a double (amyloid precursor protein-tau) transgenic: Tau phosphorylation and aggregation
-
Perez, M., Ribe, E., Rubio, A., Lim, F., Moran, M.A., Ramos, P.G., Ferrer, I., Isla, M.T. and Avila, J. (2005) Characterization of a double (amyloid precursor protein-tau) transgenic: tau phosphorylation and aggregation. Neuroscience 130, 339-347
-
(2005)
Neuroscience
, vol.130
, pp. 339-347
-
-
Perez, M.1
Ribe, E.2
Rubio, A.3
Lim, F.4
Moran, M.A.5
Ramos, P.G.6
Ferrer, I.7
Isla, M.T.8
Avila, J.9
-
35
-
-
38349013141
-
Induction of tau pathology by intracerebral infusion of amyloid-β-containing brain extract and by amyloid-β deposition in APP x tau transgenic mice
-
Bolmont, T., Clavaguera, F., Meyer-Luehmann, M., Herzig, M.C., Radde, R., Staufenbiel, M., Lewis, J., Hutton, M., Tolnay, M. and Jucker, M. (2007) Induction of tau pathology by intracerebral infusion of amyloid-β- containing brain extract and by amyloid-β deposition in APP x tau transgenic mice. Am. J. Pathol. 171, 2012-2020
-
(2007)
Am. J. Pathol.
, vol.171
, pp. 2012-2020
-
-
Bolmont, T.1
Clavaguera, F.2
Meyer-Luehmann, M.3
Herzig, M.C.4
Radde, R.5
Staufenbiel, M.6
Lewis, J.7
Hutton, M.8
Tolnay, M.9
Jucker, M.10
-
36
-
-
40449098952
-
Amyloid activates GSK-3β to aggravate neuronal tauopathy in bigenic mice
-
Terwel, D., Muyllaert, D., Dewachter, I., Borghgraef, P., Croes, S., Devijver, H. and Van Leuven, F. (2008) Amyloid activates GSK-3β to aggravate neuronal tauopathy in bigenic mice. Am. J. Pathol. 172, 786-798
-
(2008)
Am. J. Pathol.
, vol.172
, pp. 786-798
-
-
Terwel, D.1
Muyllaert, D.2
Dewachter, I.3
Borghgraef, P.4
Croes, S.5
Devijver, H.6
Van Leuven, F.7
-
37
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Aβ and synaptic dysfunction
-
Oddo, S., Caccamo, A., Shepherd, J.D., Murphy, M.P., Golde, T.E., Kayed, R., Metherate, R., Mattson, M.P., Akbari, Y. and LaFerla, F.M. (2003) Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Aβ and synaptic dysfunction. Neuron 39, 409-421
-
(2003)
Neuron
, vol.39
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
Metherate, R.7
Mattson, M.P.8
Akbari, Y.9
LaFerla, F.M.10
-
38
-
-
4043167747
-
Aβ immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
-
Oddo, S., Billings, L., Kesslak, J.-P., Cribbs, D.H. and LaFerla, F.M. (2004) Aβ immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome. Neuron 43, 321-332
-
(2004)
Neuron
, vol.43
, pp. 321-332
-
-
Oddo, S.1
Billings, L.2
Kesslak, J.-P.3
Cribbs, D.H.4
LaFerla, F.M.5
-
39
-
-
0035943436
-
Formation of neurofibrillary tangles in P301L tau transgenic mice induced by Aβ42 fibrils
-
Götz, J., Chen, F., Van Dorpe, J. and Nitsch, R.M. (2001) Formation of neurofibrillary tangles in P301L tau transgenic mice induced by Aβ42 fibrils. Science 293, 1491-1495
-
(2001)
Science
, vol.293
, pp. 1491-1495
-
-
Götz, J.1
Chen, F.2
Van Dorpe, J.3
Nitsch, R.M.4
-
40
-
-
27744435409
-
Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice
-
Ribe, E.M., Perez, M., Puig, B., Gich, I., Lim, F., Cuadrado, M., Sesma, T., Catena, S., Sanchez, B., Nieto, M. et al. (2005) Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice. Neurobiol. Dis. 20, 814-822
-
(2005)
Neurobiol. Dis.
, vol.20
, pp. 814-822
-
-
Ribe, E.M.1
Perez, M.2
Puig, B.3
Gich, I.4
Lim, F.5
Cuadrado, M.6
Sesma, T.7
Catena, S.8
Sanchez, B.9
Nieto, M.10
-
41
-
-
34547464672
-
Genetically augmenting tau levels does not modulate the onset or progression of Aβ pathology in transgenic mice
-
Oddo, S., Caccamo, A., Cheng, D., Jouleh, B., Torp, R. and LaFerla, F.M. (2007) Genetically augmenting tau levels does not modulate the onset or progression of Aβ pathology in transgenic mice. J. Neurochem. 102, 1053-1063
-
(2007)
J. Neurochem.
, vol.102
, pp. 1053-1063
-
-
Oddo, S.1
Caccamo, A.2
Cheng, D.3
Jouleh, B.4
Torp, R.5
LaFerla, F.M.6
-
42
-
-
33749521100
-
Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: Potential factors in amyloid plaque formation
-
Oakley, H., Cole, S.L., Logan, S., Maus, E., Shao, P., Craft, J., Guillozet-Bongaarts, A., Ohno, M., Disterhoft, J., Van Eldik, L. et al. (2006) Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation. J. Neurosci. 26, 10129-10140
-
(2006)
J. Neurosci.
, vol.26
, pp. 10129-10140
-
-
Oakley, H.1
Cole, S.L.2
Logan, S.3
Maus, E.4
Shao, P.5
Craft, J.6
Guillozet-Bongaarts, A.7
Ohno, M.8
Disterhoft, J.9
Van Eldik, L.10
-
43
-
-
23844494418
-
Mechanisms of memory loss in Aβ and tau mouse models
-
Ashe, K.H. (2005) Mechanisms of memory loss in Aβ and tau mouse models. Biochem. Soc. Trans. 33, 591-594
-
(2005)
Biochem. Soc. Trans.
, vol.33
, pp. 591-594
-
-
Ashe, K.H.1
-
44
-
-
51449096696
-
Aβ inhibits the proteasome and enhances amyloid and tau accumulation
-
Tseng, B.P., Green, K.N., Chan, J.L., Blurton-Jones, M. and LaFerla, F.M. (2008) Aβ inhibits the proteasome and enhances amyloid and tau accumulation. Neurobiol. Aging 29, 1607-1618
-
(2008)
Neurobiol. Aging
, vol.29
, pp. 1607-1618
-
-
Tseng, B.P.1
Green, K.N.2
Chan, J.L.3
Blurton-Jones, M.4
LaFerla, F.M.5
-
45
-
-
41149176407
-
Lack of pathology in a triple transgenic mouse model of Alzheimer's disease after overexpression of the anti-apoptotic protein Bcl-2
-
Rohn, T.T., Vyas, V., Hernandez-Estrada, T., Nichol, K.E., Christie, L.A. and Head, E. (2008) Lack of pathology in a triple transgenic mouse model of Alzheimer's disease after overexpression of the anti-apoptotic protein Bcl-2. J. Neurosci. 28, 3051-3059
-
(2008)
J. Neurosci.
, vol.28
, pp. 3051-3059
-
-
Rohn, T.T.1
Vyas, V.2
Hernandez-Estrada, T.3
Nichol, K.E.4
Christie, L.A.5
Head, E.6
-
46
-
-
0037197836
-
Tau is essential to β-amyloid-induced neurotoxicity
-
Rapoport, M., Dawson, H.N., Binder, L.I., Vitek, M.P. and Ferreira, A. (2002) Tau is essential to β-amyloid-induced neurotoxicity. Proc. Natl. Acad. Sci. U.S.A. 99, 6364-6369
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 6364-6369
-
-
Rapoport, M.1
Dawson, H.N.2
Binder, L.I.3
Vitek, M.P.4
Ferreira, A.5
-
47
-
-
34248181511
-
Reducing endogenous tau ameliorates amyloid β-induced deficits in an Alzheimer's disease mouse model
-
Roberson, E.D., Scearce-Levie, K., Palop, J.J., Yan, F.R., Cheng, I.H., Wu, T., Gerstein, H., Yu, G.Q. and Mucke, L. (2007) Reducing endogenous tau ameliorates amyloid β-induced deficits in an Alzheimer's disease mouse model. Science 316, 750-754
-
(2007)
Science
, vol.316
, pp. 750-754
-
-
Roberson, E.D.1
Scearce-Levie, K.2
Palop, J.J.3
Yan, F.R.4
Cheng, I.H.5
Wu, T.6
Gerstein, H.7
Yu, G.Q.8
Mucke, L.9
-
48
-
-
0035152814
-
Neurotrophins are required for nerve growth during development
-
Tucker, K.L., Meyer, M. and Barde, Y.A. (2001) Neurotrophins are required for nerve growth during development. Nat. Neurosci. 4, 29-37
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 29-37
-
-
Tucker, K.L.1
Meyer, M.2
Barde, Y.A.3
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