-
1
-
-
0033850407
-
Tau protein isoforms: Phosphorylation and role in neurodegenerative disorders
-
Buée, L., Bussière, T., Buée-Scherrer, V., Delacourte, A. and Hof, P.R. (2000) Tau protein isoforms: phosphorylation and role in neurodegenerative disorders. Brain Res. Rev. 33, 95-130
-
(2000)
Brain Res. Rev.
, vol.33
, pp. 95-130
-
-
Buée, L.1
Bussière, T.2
Buée-Scherrer, V.3
Delacourte, A.4
Hof, P.R.5
-
2
-
-
0025098891
-
Inhibition of neurite polarity by tau antisense oligonucleotides in primary cerebellar neurons
-
Caceres, A. and Kosik, K.S. (1990) Inhibition of neurite polarity by tau antisense oligonucleotides in primary cerebellar neurons. Nature 343, 461-463
-
(1990)
Nature
, vol.343
, pp. 461-463
-
-
Caceres, A.1
Kosik, K.S.2
-
3
-
-
0028301455
-
Altered microtubule organization in small-calibre axons of mice lacking tau protein
-
Harada, A., Oguchi, K., Okabe, S., Kuno, J., Terada, S., Ohshima, T., Sato-Yoshitake, R., Takei, Y., Noda, T. and Hirokawa, N. (1994) Altered microtubule organization in small-calibre axons of mice lacking tau protein. Nature 369, 488-491
-
(1994)
Nature
, vol.369
, pp. 488-491
-
-
Harada, A.1
Oguchi, K.2
Okabe, S.3
Kuno, J.4
Terada, S.5
Ohshima, T.6
Sato-Yoshitake, R.7
Takei, Y.8
Noda, T.9
Hirokawa, N.10
-
4
-
-
0035067021
-
Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice
-
Dawson, H.N., Ferreira, A., Eyster, M.V., Ghoshal, N., Binder, L.I. and Vitek, M.P. (2001) Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice. J. Cell Sci. 114, 1179-1187
-
(2001)
J. Cell Sci.
, vol.114
, pp. 1179-1187
-
-
Dawson, H.N.1
Ferreira, A.2
Eyster, M.V.3
Ghoshal, N.4
Binder, L.I.5
Vitek, M.P.6
-
5
-
-
0035152814
-
Neurotrophins are required for nerve growth during development
-
Tucker, K.L., Meyer, M. and Barde, Y.A. (2001) Neurotrophins are required for nerve growth during development. Nat. Neurosci. 4, 29-37
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 29-37
-
-
Tucker, K.L.1
Meyer, M.2
Barde, Y.A.3
-
6
-
-
0033969771
-
Muscle weakness, hyperactivity, and impairment in fear conditioning in tau-deficient mice
-
Ikegami, S., Harada, A. and Hirokawa, N. (2000) Muscle weakness, hyperactivity, and impairment in fear conditioning in tau-deficient mice. Neurosci. Lett. 279, 129-132
-
(2000)
Neurosci. Lett.
, vol.279
, pp. 129-132
-
-
Ikegami, S.1
Harada, A.2
Hirokawa, N.3
-
7
-
-
49549083278
-
Histone deacetylase 6 interacts with the microtubule-associated protein tau
-
Ding, H., Dolan, P.J. and Johnson, G.V. (2008) Histone deacetylase 6 interacts with the microtubule-associated protein tau. J. Neurochem. 106, 2119-2130
-
(2008)
J. Neurochem.
, vol.106
, pp. 2119-2130
-
-
Ding, H.1
Dolan, P.J.2
Johnson, G.V.3
-
8
-
-
65949122957
-
Tau: An inhibitor of deacetylase HDAC6 function
-
Perez, M., Santa-Maria, I., de Barreda, E.G., Zhu, X.W., Cuadros, R., Cabrero, J.R., Sanchez-Madrid, F., Dawson, H.N., Vitek, M.P., Perry, G. et al. (2009) Tau: an inhibitor of deacetylase HDAC6 function. J. Neurochem. 109, 1756-1766
-
(2009)
J. Neurochem.
, vol.109
, pp. 1756-1766
-
-
Perez, M.1
Santa-Maria, I.2
De Barreda, E.G.3
Zhu, X.W.4
Cuadros, R.5
Cabrero, J.R.6
Sanchez-Madrid, F.7
Dawson, H.N.8
Vitek, M.P.9
Perry, G.10
-
9
-
-
77951812710
-
Essential role of tau phosphorylation in adult hippocampal neurogenesis
-
doi:10.1002/hipo.20712
-
Hong, X.P., Peng, C.X., Wei, W., Tian, Q., Liu, Y.H., Yao, X.Q., Zhang, Y., Cao, F.Y., Wang, Q. and Wang, J.Z. (2009) Essential role of tau phosphorylation in adult hippocampal neurogenesis. Hippocampus, doi:10.1002/hipo.20712
-
(2009)
Hippocampus
-
-
Hong, X.P.1
Peng, C.X.2
Wei, W.3
Tian, Q.4
Liu, Y.H.5
Yao, X.Q.6
Zhang, Y.7
Cao, F.Y.8
Wang, Q.9
Wang, J.Z.10
-
10
-
-
33847194237
-
Hereditary frontotemporal dementia caused by Tau gene mutations
-
van Swieten, J. and Spillantini, M.G. (2007) Hereditary frontotemporal dementia caused by Tau gene mutations. Brain Pathol. 17, 63-73
-
(2007)
Brain Pathol.
, vol.17
, pp. 63-73
-
-
Van Swieten, J.1
Spillantini, M.G.2
-
11
-
-
56049124560
-
Knock-out and transgenic mouse models of tauopathies
-
Denk, F. and Wade-Martins, R. (2009) Knock-out and transgenic mouse models of tauopathies. Neurobiol. Aging 30, 1-13
-
(2009)
Neurobiol. Aging
, vol.30
, pp. 1-13
-
-
Denk, F.1
Wade-Martins, R.2
-
12
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Aβ and synaptic dysfunction
-
Oddo, S., Caccamo, A., Shepherd, J.D., Murphy, M.P., Golde, T.E., Kayed, R., Metherate, R., Mattson, M.P., Akbari, Y. and LaFerla, F.M. (2003) Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Aβ and synaptic dysfunction. Neuron 39, 409-421
-
(2003)
Neuron
, vol.39
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
Metherate, R.7
Mattson, M.P.8
Akbari, Y.9
Laferla, F.M.10
-
13
-
-
12344306018
-
Characterization of a double (amyloid precursor protein-tau) transgenic: Tau phosphorylation and aggregation
-
Perez, M., Ribe, E., Rubio, A., Lim, F., Moran, M.A., Ramos, P.G., Ferrer, I., Isla, M.T. and Avila, J. (2005) Characterization of a double (amyloid precursor protein-tau) transgenic: tau phosphorylation and aggregation. Neuroscience 130, 339-347
-
(2005)
Neuroscience
, vol.130
, pp. 339-347
-
-
Perez, M.1
Ribe, E.2
Rubio, A.3
Lim, F.4
Moran, M.A.5
Ramos, P.G.6
Ferrer, I.7
Isla, M.T.8
Avila, J.9
-
14
-
-
40449098952
-
Amyloid activates GSK-3β to aggravate neuronal tauopathy in bigenic mice
-
Terwel, D., Muyllaert, D., Dewachter, I., Borghgraef, P., Croes, S., Devijver, H. and Van Leuven, F. (2008) Amyloid activates GSK-3β to aggravate neuronal tauopathy in bigenic mice. Am. J. Pathol. 172, 786-798
-
(2008)
Am. J. Pathol.
, vol.172
, pp. 786-798
-
-
Terwel, D.1
Muyllaert, D.2
Dewachter, I.3
Borghgraef, P.4
Croes, S.5
Devijver, H.6
Van Leuven, F.7
-
15
-
-
33746652117
-
Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits
-
Schindowski, K., Bretteville, A., Leroy, K., Begard, S., Brion, J.P., Hamdane, M. and Buée, L. (2006) Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits. Am. J. Pathol. 169, 599-616
-
(2006)
Am. J. Pathol.
, vol.169
, pp. 599-616
-
-
Schindowski, K.1
Bretteville, A.2
Leroy, K.3
Begard, S.4
Brion, J.P.5
Hamdane, M.6
Buée, L.7
-
16
-
-
34548829896
-
Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice
-
Leroy, K., Bretteville, A., Schindowski, K., Gilissen, E., Authelet, M., De Decker, R., Yilmaz, Z., Buée, L. and Brion, J.P. (2007) Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice. Am. J. Pathol. 171, 976-992
-
(2007)
Am. J. Pathol.
, vol.171
, pp. 976-992
-
-
Leroy, K.1
Bretteville, A.2
Schindowski, K.3
Gilissen, E.4
Authelet, M.5
De Decker, R.6
Yilmaz, Z.7
Buée, L.8
Brion, J.P.9
-
17
-
-
0345580607
-
Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer disease
-
Brion, J.P., Tremp, G. and Octave, J.N. (1999) Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer disease. Am. J. Pathol. 154, 255-270
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 255-270
-
-
Brion, J.P.1
Tremp, G.2
Octave, J.N.3
-
18
-
-
0028965635
-
Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform
-
Götz, J., Probst, A., Spillantini, M.G., Schäfer, T., Jakes, R., Bürki, K. and Goedert, M. (1995) Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform. EMBO J. 14, 1304-1313
-
(1995)
EMBO J.
, vol.14
, pp. 1304-1313
-
-
Götz, J.1
Probst, A.2
Spillantini, M.G.3
Schäfer, T.4
Jakes, R.5
Bürki, K.6
Goedert, M.7
-
19
-
-
0036685608
-
Transgenic mouse model of tauopathies with glial pathology and nervous system degeneration
-
Higuchi, M., Ishihara, T., Zhang, B., Hong, M., Andreadis, A., Trojanowski, J.Q. and Lee, V.M.Y. (2002) Transgenic mouse model of tauopathies with glial pathology and nervous system degeneration. Neuron 35, 433-446
-
(2002)
Neuron
, vol.35
, pp. 433-446
-
-
Higuchi, M.1
Ishihara, T.2
Zhang, B.3
Hong, M.4
Andreadis, A.5
Trojanowski, J.Q.6
Lee, V.M.Y.7
-
20
-
-
0033230886
-
Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform
-
Ishihara, T., Hong, M., Zhang, B., Nakagawa, Y., Lee, M.K., Trojanowski, J.Q. and Lee, V.M.Y. (1999) Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform. Neuron 24, 751-762
-
(1999)
Neuron
, vol.24
, pp. 751-762
-
-
Ishihara, T.1
Hong, M.2
Zhang, B.3
Nakagawa, Y.4
Lee, M.K.5
Trojanowski, J.Q.6
Lee, V.M.Y.7
-
21
-
-
0035134081
-
Age-dependent induction of congophilic neurofibrillary tau inclusions in tau transgenic mice
-
Ishihara, T., Zhang, B., Higuchi, M., Yoshiyama, Y., Trojanowski, J.Q. and Lee, V.M.Y. (2001) Age-dependent induction of congophilic neurofibrillary tau inclusions in tau transgenic mice. Am. J. Pathol. 158, 555-562
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 555-562
-
-
Ishihara, T.1
Zhang, B.2
Higuchi, M.3
Yoshiyama, Y.4
Trojanowski, J.Q.5
Lee, V.M.Y.6
-
22
-
-
0342803685
-
Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein
-
Probst, A., Götz, J., Wiederhold, K.H., Tolnay, M., Mistl, C., Jaton, A.L., Hong, M., Ishihara, T., Lee, V.M.Y., Trojanowski, J.Q. et al. (2000) Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein. Acta Neuropathol. 99, 469-481
-
(2000)
Acta Neuropathol.
, vol.99
, pp. 469-481
-
-
Probst, A.1
Götz, J.2
Wiederhold, K.H.3
Tolnay, M.4
Mistl, C.5
Jaton, A.L.6
Hong, M.7
Ishihara, T.8
Lee, V.M.Y.9
Trojanowski, J.Q.10
-
23
-
-
0034016093
-
Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes
-
Duff, K., Knight, H., Refolo, L.M., Sanders, S., Yu, X., Picciano, M., Malester, B., Hutton, M., Adamson, J., Goedert, M. et al. (2000) Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes. Neurobiol. Dis. 7, 87-98
-
(2000)
Neurobiol. Dis.
, vol.7
, pp. 87-98
-
-
Duff, K.1
Knight, H.2
Refolo, L.M.3
Sanders, S.4
Yu, X.5
Picciano, M.6
Malester, B.7
Hutton, M.8
Adamson, J.9
Goedert, M.10
-
24
-
-
0041803006
-
Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms
-
Andorfer, C., Kress, Y., Espinoza, M., De Silva, R., Tucker, K.L., Barde, Y.A., Duff, K. and Davies, P. (2003) Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms. J. Neurochem. 86, 582-590
-
(2003)
J. Neurochem.
, vol.86
, pp. 582-590
-
-
Andorfer, C.1
Kress, Y.2
Espinoza, M.3
De Silva, R.4
Tucker, K.L.5
Barde, Y.A.6
Duff, K.7
Davies, P.8
-
25
-
-
20044367108
-
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms
-
Andorfer, C., Acker, C.M., Kress, Y., Hof, P.R., Duff, K. and Davies, P. (2005) Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms. J. Neurosci. 25, 5446-5454
-
(2005)
J. Neurosci.
, vol.25
, pp. 5446-5454
-
-
Andorfer, C.1
Acker, C.M.2
Kress, Y.3
Hof, P.R.4
Duff, K.5
Davies, P.6
-
26
-
-
13644268449
-
Changed conformation of mutant tau-P301L underlies the moribund tauopathy, absent in progressive, nonlethal axonopathy of tau-4R/2N transgenic mice
-
Terwel, D., Lasrado, R., Snauwaert, J., Vandeweert, E., Van Haesendonck, C., Borghgraef, P. and Van Leuven, F. (2005) Changed conformation of mutant tau-P301L underlies the moribund tauopathy, absent in progressive, nonlethal axonopathy of tau-4R/2N transgenic mice. J. Biol. Chem. 280, 3963-3973
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 3963-3973
-
-
Terwel, D.1
Lasrado, R.2
Snauwaert, J.3
Vandeweert, E.4
Van Haesendonck, C.5
Borghgraef, P.6
Van Leuven, F.7
-
27
-
-
0036850725
-
Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein
-
Allen, B., Ingram, E., Takao, M., Smith, M.J., Jakes, R., Virdee, K., Yoshida, H., Holzer, M., Craxton, M., Emson, P.C. et al. (2002) Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein. J. Neurosci. 22, 9340-9351
-
(2002)
J. Neurosci.
, vol.22
, pp. 9340-9351
-
-
Allen, B.1
Ingram, E.2
Takao, M.3
Smith, M.J.4
Jakes, R.5
Virdee, K.6
Yoshida, H.7
Holzer, M.8
Craxton, M.9
Emson, P.C.10
-
28
-
-
67650077008
-
Transmission and spreading of tauopathy in transgenic mouse brain
-
Clavaguera, F., Bolmont, T., Crowther, R.A., Abramowski, D., Frank, S., Probst, A., Fraser, G., Stalder, A.K., Beibel, M., Staufenbiel, M. et al. (2009) Transmission and spreading of tauopathy in transgenic mouse brain. Nat. Cell Biol. 11, 909-913
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 909-913
-
-
Clavaguera, F.1
Bolmont, T.2
Crowther, R.A.3
Abramowski, D.4
Frank, S.5
Probst, A.6
Fraser, G.7
Stalder, A.K.8
Beibel, M.9
Staufenbiel, M.10
-
29
-
-
0032938625
-
Assembly of paired helical filaments from mouse tau: Implications for the neurofibrillary pathology in transgenic mouse models for Alzheimer's disease
-
Kampers, T., Pangalos, M., Geerts, H., Wiech, H. and Mandelkow, E. (1999) Assembly of paired helical filaments from mouse tau: implications for the neurofibrillary pathology in transgenic mouse models for Alzheimer's disease. FEBS Lett. 451, 39-44
-
(1999)
FEBS Lett.
, vol.451
, pp. 39-44
-
-
Kampers, T.1
Pangalos, M.2
Geerts, H.3
Wiech, H.4
Mandelkow, E.5
-
30
-
-
33947495186
-
Post-translational modifications of tau protein
-
Pevalova, M., Filipcik, P., Novak, M., Avila, J. and Iqbal, K. (2006) Post-translational modifications of tau protein. Bratisl. Lek. Listy 107, 346-353
-
(2006)
Bratisl. Lek. Listy
, vol.107
, pp. 346-353
-
-
Pevalova, M.1
Filipcik, P.2
Novak, M.3
Avila, J.4
Iqbal, K.5
-
31
-
-
61849088424
-
Tau phosphorylation: The therapeutic challenge for neurodegenerative disease
-
Hanger, D.P., Anderton, B.H. and Noble, W. (2009) Tau phosphorylation: the therapeutic challenge for neurodegenerative disease. Trends Mol. Med. 15, 112-119
-
(2009)
Trends Mol. Med.
, vol.15
, pp. 112-119
-
-
Hanger, D.P.1
Anderton, B.H.2
Noble, W.3
-
32
-
-
0028049937
-
Casein kinase II preferentially phosphorylates human tau isoforms containing an amino-terminal insert: Identification of threonine 39 as the primary phosphate acceptor
-
Greenwood, J.A., Scott, C.W., Spreen, R.C., Caputo, C.B. and Johnson, G.V.W. (1994) Casein kinase II preferentially phosphorylates human tau isoforms containing an amino-terminal insert: identification of threonine 39 as the primary phosphate acceptor. J. Biol. Chem. 269, 4373-4380
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 4373-4380
-
-
Greenwood, J.A.1
Scott, C.W.2
Spreen, R.C.3
Caputo, C.B.4
Johnson, G.V.W.5
-
33
-
-
34548191034
-
Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis
-
Hanger, D.P., Byers, H.L., Wray, S., Leung, K.Y., Saxton, M.J., Seereeram, A., Reynolds, C.H., Ward, M.A. and Anderton, B.H. (2007) Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis. J. Biol. Chem. 282, 23645-23654
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 23645-23654
-
-
Hanger, D.P.1
Byers, H.L.2
Wray, S.3
Leung, K.Y.4
Saxton, M.J.5
Seereeram, A.6
Reynolds, C.H.7
Ward, M.A.8
Anderton, B.H.9
-
34
-
-
0024808569
-
Aberrant protein phosphorylation and cytoarchitecture in Alzheimer's disease
-
Saitoh, T. and Iimoto, D. (1989) Aberrant protein phosphorylation and cytoarchitecture in Alzheimer's disease. Prog. Clin. Biol. Res. 317, 769-780
-
(1989)
Prog. Clin. Biol. Res.
, vol.317
, pp. 769-780
-
-
Saitoh, T.1
Iimoto, D.2
-
35
-
-
12144288564
-
Phosphorylation of tau by fyn: Implications for Alzheimer's disease
-
Lee, G., Thangavel, R., Sharma, V.M., Litersky, J.M., Bhaskar, K., Fang, S.M., Do, L.H., Andreadis, A., Van Hoesen, G. and Ksiezak-Reding, H. (2004) Phosphorylation of tau by fyn: implications for Alzheimer's disease. J. Neurosci. 24, 2304-2312
-
(2004)
J. Neurosci.
, vol.24
, pp. 2304-2312
-
-
Lee, G.1
Thangavel, R.2
Sharma, V.M.3
Litersky, J.M.4
Bhaskar, K.5
Fang, S.M.6
Do, L.H.7
Andreadis, A.8
Van Hoesen, G.9
Ksiezak-Reding, H.10
-
37
-
-
0029872638
-
Structure, microtubule interactions, and phosphorylation of tau protein
-
Mandelkow, E.M., Schweers, O., Drewes, G., Biernat, J., Gustke, N., Trinczek, B. and Mandelkow, E. (1996) Structure, microtubule interactions, and phosphorylation of tau protein. Ann. N.Y. Acad. Sci. 777, 96-106
-
(1996)
Ann. N.Y. Acad. Sci.
, vol.777
, pp. 96-106
-
-
Mandelkow, E.M.1
Schweers, O.2
Drewes, G.3
Biernat, J.4
Gustke, N.5
Trinczek, B.6
Mandelkow, E.7
-
38
-
-
12644260802
-
The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology
-
Carmel, G., Mager, E.M., Binder, L.I. and Kuret, J. (1996) The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology. J. Biol. Chem. 271, 32789-32795
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32789-32795
-
-
Carmel, G.1
Mager, E.M.2
Binder, L.I.3
Kuret, J.4
-
39
-
-
0030936599
-
Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau
-
Jicha, G.A., Bowser, R., Kazam, I.G. and Davies, P. (1997) Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau. J. Neurosci. Res. 48, 128-132
-
(1997)
J. Neurosci. Res.
, vol.48
, pp. 128-132
-
-
Jicha, G.A.1
Bowser, R.2
Kazam, I.G.3
Davies, P.4
-
40
-
-
10944248857
-
Tau, tangles, and Alzheimer's disease
-
Binder, L.I., Guillozet-Bongaarts, A.L., Garcia-Sierra, F. and Berry, R.W. (2005) Tau, tangles, and Alzheimer's disease. Biochim. Biophys. Acta 1739, 216-223
-
(2005)
Biochim. Biophys. Acta
, vol.1739
, pp. 216-223
-
-
Binder, L.I.1
Guillozet-Bongaarts, A.L.2
Garcia-Sierra, F.3
Berry, R.W.4
-
41
-
-
0034282067
-
Conformational change as one of the earliest alterations of tan in Alzheimer's disease
-
Weaver, C.L., Espinoza, M., Kress, Y. and Davies, P. (2000) Conformational change as one of the earliest alterations of tan in Alzheimer's disease. Neurobiol. Aging 21, 719-727
-
(2000)
Neurobiol. Aging
, vol.21
, pp. 719-727
-
-
Weaver, C.L.1
Espinoza, M.2
Kress, Y.3
Davies, P.4
-
42
-
-
0025753852
-
The molecular pathology of Alzheimer's disease
-
Selkoe, D.J. (1991) The molecular pathology of Alzheimer's disease. Neuron 6, 487-498
-
(1991)
Neuron
, vol.6
, pp. 487-498
-
-
Selkoe, D.J.1
-
43
-
-
0026597063
-
Alzheimer's disease: The amyloid cascade hypothesis
-
Hardy, J.A. and Higgins, G.A. (1992) Alzheimer's disease: the amyloid cascade hypothesis. Science 256, 184-185
-
(1992)
Science
, vol.256
, pp. 184-185
-
-
Hardy, J.A.1
Higgins, G.A.2
-
44
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy, J. and Selkoe, D.J. (2002) The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297, 353-356
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
45
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
-
Games, D., Adams, D., Alessandrini, R., Barbour, R., Berthelette, P., Blackwell, C., Carr, T., Clemens, J., Donaldson, T., Gillespie, F. et al. (1995) Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature 373, 523-527
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
Carr, T.7
Clemens, J.8
Donaldson, T.9
Gillespie, F.10
-
46
-
-
0029742199
-
Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice
-
Hsiao, K., Chapman, P., Nilsen, S., Eckman, C., Harigaya, Y., Younkin, S., Yang, F.S. and Cole, G. (1996) Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice. Science 274, 99-102
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.S.7
Cole, G.8
-
47
-
-
0035936683
-
Sw mice
-
Sw mice. Neurosci. Lett. 299, 169-172
-
(2001)
Neurosci. Lett.
, vol.299
, pp. 169-172
-
-
Tomidokoro, Y.1
Ishiguro, K.2
Harigaya, Y.3
Matsubara, E.4
Ikeda, M.5
Park, J.M.6
Yasutake, K.7
Kawarabayashi, T.8
Okamoto, K.9
Shoji, M.10
-
48
-
-
0011444914
-
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
-
Sturchler-Pierrat, C., Abramowski, D., Duke, M., Wiederhold, K.H., Mistl, C., Rothacher, S., Ledermann, B., Bürki, K., Frey, P., Paganetti, P.A. et al. (1997) Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. Proc. Natl. Acad. Sci. U.S.A. 94, 13287-13292
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 13287-13292
-
-
Sturchler-Pierrat, C.1
Abramowski, D.2
Duke, M.3
Wiederhold, K.H.4
Mistl, C.5
Rothacher, S.6
Ledermann, B.7
Bürki, K.8
Frey, P.9
Paganetti, P.A.10
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