Human and mouse perforin are processed in part through cleavage by the lysosomal cysteine proteinase cathepsin L

Immunology

Volumn 131, Issue 2, 2010, Pages 257-267

  Konjar, Špela ^a   Sutton, Vivien R ^b   Hoves, Sabine ^b   Repnik, Urška ^a   Yagita, Hideo ^c   Reinheckel, Thomas ^d   Peters, Christoph ^d   Turk, Vito ^a   Turk, Boris ^a   Trapani, Joseph A ^b   Kopitar Jerala, Nataša ^a  

^a JO EF STEFAN INSTITUTE   (Slovenia)

^b PETER MACCALLUM CANCER CENTRE   (Australia)

^c JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

cathepsin L; cytotoxic T cells; cytotoxicity; natural killer cells; perforin deficiency

Indexed keywords

CATHEPSIN L; GRANZYME; PERFORIN;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL KILLING; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOUSE; NATURAL KILLER CELL; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PROCESSING;

ANIMALS; BIOCATALYSIS; CATHEPSIN L; CELL LINE, TUMOR; CYSTEINE PROTEINASE INHIBITORS; CYTOTOXICITY, IMMUNOLOGIC; EGTAZIC ACID; GRANZYMES; HUMANS; K562 CELLS; KILLER CELLS, NATURAL; LEUCINE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; OVALBUMIN; PEPTIDE FRAGMENTS; PEPTIDE HYDROLASES; PORE FORMING CYTOTOXIC PROTEINS; RECOMBINANT PROTEINS; T-LYMPHOCYTES, CYTOTOXIC;

EID: 77955935962     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2010.03299.x     Document Type: Article

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