Mice lacking asparaginyl endopeptidase develop disorders resembling hemophagocytic syndrome

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 2, 2009, Pages 468-473

  Chan, Chi Bun ^a   Abe, Michiyo ^b   Hashimoto, Noriyoshi ^b   Hao, Chunhai ^a   Williams, Ifor R ^a   Liu, Xia ^a   Nakao, Shinji ^b   Yamamoto, Akitsugu ^c   Li, Shi Yong ^a   Hara Nishimura, Ikuko ^d   Asano, Masahide ^b   Ye, Keqiang ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KANAZAWA UNIVERSITY   (Japan)

^c NAGAHAMA INSTITUTE OF BIO SCIENCE AND TECHNOLOGY   (Japan)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

Hematopoiesis; Legumain; Lysosomal disorder; Macrophage

Indexed keywords

CYTOKINE; LEGUMAIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CELL MEMBRANE; CLINICAL FEATURE; CONTROLLED STUDY; CYTOPENIA; ERYTHROCYTE; ERYTHROPHAGOCYTOSIS; EXTRAMEDULLARY HEMATOPOIESIS; FEVER; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; HEPATOSPLENOMEGALY; HISTIOCYTE; MOUSE; MUTANT; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; SPLEEN;

ANIMALS; BONE MARROW; CYSTEINE ENDOPEPTIDASES; HEMATOPOIESIS, EXTRAMEDULLARY; KILLER CELLS, NATURAL; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; MICE; MICE, KNOCKOUT; PANCYTOPENIA; SPLEEN; SPLENOMEGALY;

MUS;

EID: 58849134849     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0809824105     Document Type: Article

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