Actin-sequestering protein, thymosin beta-4, induces paclitaxel resistance through ROS/HIF-1α stabilization in HeLa human cervical tumor cells

Life Sciences

Volumn 87, Issue 9-10, 2010, Pages 286-293

  Oh, Jin Mi ^a   Moon, Eun Yi ^a  

^a Sejong University   (South Korea)

Author keywords

HIF 1 ; Paclitaxel; Resistance; ROS; Thymosin beta 4

Indexed keywords

ACETYLCYSTEINE; ACTIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PACLITAXEL; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; THYMOSIN BETA4;

ARTICLE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SENSITIVITY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MELANOMA; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; TRANSGENIC MOUSE; UTERINE CERVIX TUMOR; WILD TYPE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BLOTTING, WESTERN; CELL NUCLEUS; CELL SURVIVAL; CYTOSOL; DRUG RESISTANCE, NEOPLASM; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FLOW CYTOMETRY; HELA CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEOPLASM TRANSPLANTATION; NF-KAPPA B; PACLITAXEL; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THYMOSIN;

MUS; MUS MUSCULUS;

EID: 77955768685     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2010.07.002     Document Type: Article

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