In vivo high-resolution magic angle spinning magnetic resonance spectroscopy of Drosophila melanogaster at 14.1 T shows trauma in aging and in innate immune-deficiency is linked to reduced insulin signaling

International Journal of Molecular Medicine

Volumn 26, Issue 2, 2010, Pages 175-184

  Righi, Valeria ^a,b   Apidianakis, Yiorgos ^a,b   Mintzopoulos, Dionyssios ^a,b   Astrakas, Loukas ^a,b   Rahme, Laurence G ^b   Tzika, A Aria ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Aging; Biomarkers; Drosophila melanogaster; High resolution magic angle spinning; Immunity; Insulin signaling; Magnetic resonance spectroscopy; Obesity; Total through bond correlation spectroscopy

Indexed keywords

INSULIN; AKHR PROTEIN, DROSOPHILA; AMINO ACID; CHICO PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; GLUCAGON RECEPTOR; IMMUNE DEFICIENCY PROTEIN, DROSOPHILA; INSULIN RECEPTOR SUBSTRATE; LIPID; SIGNAL PEPTIDE;

AGED; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; FEASIBILITY STUDY; IMMUNE DEFICIENCY; IN VIVO STUDY; INJURY; INNATE IMMUNITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SIGNAL TRANSDUCTION; AGE; ANALYSIS OF VARIANCE; ANIMAL; CHEMISTRY; GENETICS; LIPID METABOLISM; MALE; METABOLISM; PHYSIOLOGY; PROCEDURES;

AGE FACTORS; AMINO ACIDS; ANALYSIS OF VARIANCE; ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; IMMUNOLOGIC DEFICIENCY SYNDROMES; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPID METABOLISM; LIPIDS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; RECEPTORS, GLUCAGON; SIGNAL TRANSDUCTION; WOUNDS AND INJURIES;

EID: 77955752844     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm_00000450     Document Type: Article

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