Distribution of Intramyocellular Lipids in Human Calf Muscles as Determined by MR Spectroscopic Imaging

Magnetic Resonance in Medicine

Volumn 51, Issue 2, 2004, Pages 253-262

  Vermathen, Peter ^a   Kreis, Roland ^a   Boesch, Chris ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Fiber orientation; Intramyocellular lipids; Lipid extrapolation; MR spectroscopic imaging; Skeletal muscle

Indexed keywords

AMINO ACIDS; EXTRAPOLATION; FIBER REINFORCED MATERIALS; IMAGE SEGMENTATION; LIPIDS; METABOLITES;

BIOMECHANICAL PROPERTIES; DIPOLAR COUPLINGS; GASTROCNEMIUS MUSCLE; MR SPECTROSCOPIC IMAGING; ORIENTATION DEPENDENT; SKELETAL MUSCLE; SPECTROSCOPIC IMAGING; TIBIALIS ANTERIOR;

MUSCLE;

CREATINE; LIPID; TAURINE;

ADULT; ARTICLE; CLINICAL ARTICLE; FEMALE; GASTROCNEMIUS MUSCLE; HUMAN; IMAGING; MALE; METABOLITE; MUSCLE CELL; MUSCLE TISSUE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; SKELETAL MUSCLE; SOLEUS MUSCLE; TIBIALIS ANTERIOR MUSCLE; TIBIALIS POSTERIOR MUSCLE;

EID: 0842264091     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.10721     Document Type: Article

References (33)

1. Schick F, Eismann B, Jung WI, Bongers H, Bunse M, Lutz O. Comparison of localized proton NMR signals of skeletal muscle and fat tissue in vivo: two lipid compartments in muscle tissue. Magn Reson Med 1993;29:158-167.
2. Boesch C, Slotboom J, Hoppeler H, Kreis R. In vivo determination of intra-myocellular lipids in human muscle by means of localized 1H-MR spectroscopy. Magn Reson Med 1997;37:484-493.
3. Jacob S, Machann J, Rett K, Brechtel K, Volk A, Renn W, Maerker E, Matthaei S, Schick F, Claussen CD, Haring HU. Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects. Diabetes 1999;48:1113-1119.
4. Krssak M, Falk Petersen K, Dresner A, DiPietro L, Vogel SM, Rothman DL, Roden M, Shulman GI. Intramyocellular-lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. Diabetologia 1999;42:113-116.
5. Hwang JH, Pan JW, Heydari S, Hetherington HP, Stein DT. Regional differences in intramyocellular lipids in humans observed by in vivo 1H-MR spectroscopic imaging. J Appl Physiol 2001;90:1267-1274.
6. Larson-Meyer DE, Newcomer BR, Hunter GR. Influence of endurance running and recovery diet on intramyocellular lipid content in women: a 1H NMR study. Am J Physiol Endocrinol Metab 2002;282: E95-E106.
7. Howald H, Boesch C, Kreis R, Matter S, Billeter R, Essen-Gustavsson B, Hoppeler H. Content of intramyocellular lipids derived by electron microscopy, biochemical assays, and 1H-MR spectroscopy. J Appl Physiol 2002;92:2264-2272.
8. Watt MJ, Heigenhauser GJ, Spriet LL. Intramuscular triacylglycerol utilization in human skeletal muscle during exercise: is there a controversy? J Appl Physiol 2002;93:1185-1195.
9. Haupt CI, Schuff N, Weiner MW, Maudsley AA. Removal of lipid artifacts in 1H spectroscopic imaging by data extrapolation. Magn Reson Med 1996;35:678-687.
10. Rico-Sanz J, Thomas EL, Jenkinson G, Mierisova S, Iles R, Bell JD. Diversity in levels of intracellular total creatine and triglycerides in human skeletal muscles observed by (1)H-MRS. J Appl Physiol 1999;87:2068-2072.
11. Decombaz J, Schmitt B, Ith M, Decarli B, Diem P, Kreis R, Hoppeler H, Boesch C. Postexercise fat intake repletes intramyocellular lipids, but no faster in trained than in sedentary subjects. Am J Physiol Regul Integr Comp Physiol 2001;281:R760-R769.
12. Vermathen P, Boesch C, Kreis R. Mapping fiber orientation in human muscle by proton MR spectroscopic imaging. Magn Reson Med 2003;49:424-432.
13. Kreis R, Boesch C. Spatially localized, one- and two-dimensional NMR spectroscopy and in vivo application to human muscle. J Magn Reson Ser B 1996;113:103-118.
14. Slotboom J, Boesch C, Kreis R. Versatile frequency domain fitting using time domain models and prior knowledge. Magn Reson Med 1998;39:899-911.
15. Steidle G, Machann J, Claussen CD, Schick F. Separation of intra- and extramyocellular lipid signals in proton MR spectra by determination of their magnetic field distribution. J Magn Reson 2002;154:228-235.
16. Kelso TB, Hodgson DR, Visscher AR, Gollnick PD. Some properties of different skeletal muscle fiber types: comparison of reference bases. J Appl Physiol 1987;62:1436-1441.
17. Kreis R, Kamber M, Koster M, Felblinger J, Slotboom J, Hoppeler H, Boesch C. Creatine supplementation. Part II: in vivo magnetic resonance spectroscopy. Med Sci Sports Exerc 1999;31:1770-1777.
18. Michaelis T, Merboldt KD, Bruhn H, Hänicke W, Frahm J. Absolute concentrations of metabolites in the adult human brain in vivo: quantification of localized proton MR spectra. Radiology 1993;187:219-227.
19. Vermathen P, Kreis R, Boesch C. Metabolite quantitation in muscles using 1H MR spectroscopic imaging and validation by single voxel MR spectroscopy. In: Proceedings of the 11th Annual Meeting of ISMRM, Toronto, Canada, 2003. p 1152.
20. Boesch C. Kreis R. Observation of intramyocellular lipids by 1H-magnetic resonance spectroscopy. Ann NY Acad Sci 2000;904:25-31.
21. Essen B. Intramuscular substrate utilization during prolonged exercise. Ann NY Acad Sci 1977;301:30-44.
22. Howald H, Hoppeler H, Claassen H, Mathieu O, Straub R. Influences of endurance training on the ultrastructural composition of the different muscle fiber types in humans. Pflugers Arch 1985;403:369-376.
23. Johnson MA, Polgar J, Weightman D, Appleton D. Data on the distribution of fibre types in thirty-six human muscles. An autopsy study. J Neurol Sci 1973;18:111-129.
24. Porter MM, Stuart S, Boij M, Lexell J. Capillary supply of the tibialis anterior muscle in young, healthy, and moderately active men and women. J Appl Physiol 2002;92:1451-1457.
25. Burkholder TJ, Fingado B, Baron S, Lieber RL. Relationship between muscle fiber types and sizes and muscle architectural properties in the mouse hindlimb. J Morphol 1994;221:177-190.
26. Wickiewicz TL, Roy RR, Powell PL, Perrine JJ, Edgerton VR. Muscle architecture and force-velocity relationships in humans. J Appl Physiol 1984;57:435-443.
27. Kawakami Y, Ichinose Y, Fukunaga T. Architectural and functional features of human triceps surae muscles during contraction. J Appl Physiol 1998;85:398-404.
28. Blazevich AJ, Giorgi A. Effect of testosterone administration and weight training on muscle architecture. Med Sci Sports Exerc 2001;33:1688-1693.
29. Aagaard P, Andersen JL, Dyhre-Poulsen P, Leffers AM, Wagner A, Magnusson SP, Halkjaer-Kristensen J, Simonsen EB. A mechanism for increased contractile strength of human pennate muscle in response to strength training: changes in muscle architecture. J Physiol 2001;534:613-623.
30. Kawakami Y, Abe T, Fukunaga T. Muscle-fiber pennation angles are greater in hypertrophied than in normal muscles. J Appl Physiol 1993;74:2740-2744.
31. Narici M, Cerretelli P. Changes in human muscle architecture in disuse-atrophy evaluated by ultrasound imaging. J Gravit Physiol 1998;5:73-74.
32. Abe T, Kumagai K, Brechue WF. Fascicle length of leg muscles is greater in sprinters than distance runners. Med Sci Sports Exerc 2000;32:1125-1129.
33. Powell PL, Roy RR, Kanim P, Bello MA, Edgerton VR. Predictability of skeletal muscle tension from architectural determinations in guinea pig hindlimbs. J Appl Physiol 1984;57:1715-1721.